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Welnorm (Alprazolam)

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Alprazolam, available under the trade name Xanax, is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder, but also in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Welnorm, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Welnorm is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Actirax, Aderta, Alamflu, Alpram, Alprastan, Alprazan, Alpronit, Alrif, Altok, Alzex, Alzocum, Anxit, Axizox, Benzolam, Berest, Besquil, Cardilax, Emcalm, Endolam, Esteem, Finezol, Fledore, Fluxozam, Hiprazole, Kaprolam, Manzolam, Mentolift, Nexlpra, Nokzok, Orten, Pacyl, Paxor, Propnix, Sinaday, Somnirest, Suzilam, Tranax, Viprax, Xylonite, Zallpam, Zeecam, Zeprax, Zolax, Zomark

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Also known as: Alprazolam


Welnorm is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). Alprazolam affects chemicals in the brain that may be unbalanced in people with anxiety. Welnorm is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

You should not use Welnorm if you have narrow-angle glaucoma, if you also take itraconazole or ketoconazole, or if you are allergic to Welnorm or similar medicines (Valium, Ativan, Tranxene, and others).

Alprazolam may be habit-forming. Misuse of habit-forming medicine can cause addiction, overdose, or death.

Do not drink alcohol while taking Welnorm. This medication can increase the effects of alcohol. Alprazolam may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Xanax XR. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Xanax XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Xanax dosage information

Side effects

The most common side effects associated with Welnorm are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of alprazolam in the elderly. However, elderly patients are more likely to have unwanted effects (eg, severe drowsiness, dizziness, confusion, clumsiness, or unsteadiness) and kidney, liver, or lung problems, which may require caution and an adjustment in the dose for patients receiving this medicine.

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Retropharyngeal hematoma following blunt cervical spine injury is a known cause of airway obstruction, but it is not known to cause hemorrhagic shock. Finally, VBA and connectivity results were also correlated with functional outcome. While previously, dual-axis electron tomography was employed for reducing missing wedge artifacts, our work demonstrates the potential of dual-axis tomography for improving the resolution of a tomographic reconstruction, even for structures not affected by missing wedge artifacts. Relationship of structural and functional problems in bacteriophages. Changes of phenolic compounds in virgin olive oils with maturation of fruits were also studied. Understanding the benefits of breastfeeding for opioid-dependent pregnant women and their neonates will enable clinicians to safely recommend breastfeeding for long-term health of these high-risk women and their infants. Incidence of type 1 diabetes has doubled in Kuwaiti children 0-14 years over the last 20 years. Light microscopic examinations revealed numerous strands and islands of basaloid cells and keratinous cysts with desmoplastic stroma in the dermis and subcutaneous tissue. Crossmodal Association of Visual and Haptic Material Properties of Objects in the Monkey Ventral Visual Cortex. Interacting with divergent selection, restricted opportunity for gene flow may in some cases be as much a cause as a consequence of adaptation, with the latter being a hallmark of ecological speciation.

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The gender hormone has a causal role in the development of cardiovascular disease. Present results suggest that the brainstem lesions are located in the auditory pathways in patients with MID and DAT. Midkine is expressed and differentially processed during chronic obstructive pulmonary disease exacerbations and ventilator-associated pneumonia associated with Staphylococcus aureus infection. The study aim was to assess the value of quantitative Doppler echocardiography to monitor PVL severity. Airway obstruction (AO) in sarcoidosis is reported to be associated with respiratory symptoms, increased morbidity, and an increased mortality risk. To clarify the role of viral infection in otitis media, we intranasally inoculated mice with influenza A virus and examined histologic changes in the nasopharyngeal mucosa using a battery of lectins.

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Multivariate analysis was done to evaluate the association of clinicopathological features, incontinent vs continent diversion type and postoperative complications with decreased renal function. This study provides an experimental basis for the further study of miR-138-based therapy for CIR injury. This study provides a powerful glimpse at the potential effects of stress during development while accounting for shared genetic and environmental influences. We retrospectively evaluated the records of 103 patients who underwent rhinoplasty at our private clinic between April 2002 and December 2014. (ii) In accordance with the ICRP analysis of particulate retention in the lung for extended intervals, the airborne respirable particle intake should be multiplied by the factor 0.125 to generate an estimate of dosage of particles retained in the lung for extended intervals, leading to possible carcinogenesis from the Cr(VI) content. Biochemical, clinical, and sociodemographic data were collected. A striking heterogeneity between individuals within a given age group and across age groups characterized the reactivity of purified IgG and of IgG in whole serum with bacterial antigens. Nonsynonymous substitution rates revealed that the variant Sb and Ca2 sequences were being positively selected between 2009/10 and 2010/11.

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Evolutionary and population genomics studies hold great promise for providing valuable insights into natural selection, the effect of mutations on phenotypes, and the origin of species. Berger inhibit the invasion of LnCaP prostate carcinoma cells by inactivating Akt and modulating tight junctions. Prostaglandin E1 in the diagnosis and therapy of erectile disorders. Bone loss is a potentially debilitating condition in women with eating disorders. The Urinary Uric Acid/Creatinine Ratio is An Adjuvant Marker for Perinatal Asphyxia.

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In a patient presenting with Leigh syndrome, which has hitherto not been described as a clinical feature of NDUFAF3 deficiency, we identified a novel homozygous variant and confirmed its pathogenicity in patient fibroblasts studies. In particular, double-negative (DN) T cells are expanded in the peripheral blood of patients with SLE and in lupus-prone mice. (Coleoptera: Curculionidae: Scolytinae): the influence of temperature on activity. In a 4 h 51Cr release assay, these Vbeta3-positive cells exhibited tumor-specific cytotoxicity and also nonspecific effector cells are shown to be involved in tumor rejection. The results show that the activities of all preparations of TRF are markedly diminished or abrogated by antibody to Mu IFN-gamma but not by antibodies to human IFN-gamma (Hu IFN-gamma), nor by normal rabbit sera or purified rabbit Ig. Transmitted and polarized light microscopy of unerupted and erupted teeth affected by a pigmented anomaly found in two geographically isolated Polynesian populations, the New Zealand Maori and the French Polynesian Marquesas Islander, showed similar histological characteristics. The aim of this study was to assess the feasibility of Raman spectroscopy as a screening technique for chemical characterisation of tattoo pigments in pathologic reacting tattoos and tattoo ink stock products to depict unsafe pigments and metabolites of pigments.

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RNAi enables the inhibition of specific genes by sequence-specific gene silencing using a double-stranded RNA. oxLDL is increased in AF patients compared to sinus rhythm controls. Reduction in the number and associated costs of unindicated dual-phase head CT examinations after a quality improvement initiative. The -174G/C SNP is in the promoter region of the IL-6 gene and may be associated with changes in gene transcription and serum cytokine levels. It is likely that the cerebellum exerts the same effect on a number of different efferent targets. A liberase-based perfusion technique in combination with a low-speed centrifugation and magnetic-activated cell sorting (MACS) led to the isolation and purification of HCs, KCs, and LSECs with high yields and purity.

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Lactobacillus rhamnosus GG increases Toll-like receptor 3 gene expression in murine small intestine ex vivo and in vivo. A tree reflecting evolutionary relationships of prokaryotes was constructed. It can reduce damage and acute injury, as well as facilitating early recovery after major surgery. It helps researchers to reveal evolution relationships of different species. The electrostatic spark energy values predicted using this model were in good agreement with the corresponding experimental values. This prospective observational study included 198 medical patients admitted to the Emergency Department, at Odense University Hospital. All the anatomical components of the anorectal sphincter are present at birth. Relevant anatomical sites with age-dependent enamel optical characteristics corresponding to certain ratio of hydroxyapatite phases and the compliance of their color characteristics to composites enamel layers were revealed. Thirteen out of 20 (65 per cent) cases of reactive mesothelial hyperplasia showed occasional nuclear positivity for p53 and 5/20 (25 per cent) cases showed focal weak membrane staining for EMA.

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After taking clinical history and familial history, complete hemogram report was obtained by an automated cell counter. Same-day discharge after percutaneous coronary intervention: trial sequential analysis of outcomes. Previous studies have indicated that ticagrelor is well tolerated and exhibits linear pharmacokinetics up to doses of 600 mg/day. Within each study population, individual males sired more than one litter, suggesting that C. The protein distribution in the tooth-supporting structures was determined from site by amino acid analysis and was compared with the collagen distribution in tissue protein, based upon hydroxyproline content levaquin interaction with alcohol . The dynamics of water within ionic polymer networks formed by sulfonated poly(phenylene) (SPP), as revealed by quasi-elastic neutron scattering (QENS), is presented. The effects of NSAIDs, FAs or cyclooxygenase (COX) inhibitors on histamine release from human basophils concentrated by gravity separation were evaluated. AN EVALUATION OF THE GASTRIC ANTISECRETORY ACTION OF HEXOPYRRONIUM IN HUMAN SUBJECTS.

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Hemophilic arthritis cases, especially the mild or subclinical cases without family history and with an older age of onset, are not common. LIs of Fas and AIs of the preoperative therapy group were significantly higher than those of the control group. HMW adiponectin levels were associated with various metabolic risk factors in metabolically healthy women but not in metabolically healthy men. Drug interactions of zonisamide with phenytoin and sodium valproate: serum concentrations and protein is 40 mg of lipitor too much binding. To review systematically the literature on diagnostic tests and performance of second-trimester sonographic assessment of nasal bone (NB) in identifying fetuses affected by Down syndrome. Divergent phenotypes of both lean growth performance and humoral immune response are affected by significant and functional transcript abundance changes throughout the immune response. Lack of association between inguinal hernia and abdominal aortic aneurysm in a population-based male cohort. Evaluation of Outcomes in Patients With Carcinoma of the Cervix Treated With Concurrent Radiation and Cisplatin Versus Cisplatin/5-FU Compared With Radiation Alone.

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Our study of pediatric patch testing can provide information regarding common allergens in children, which can enhance patient care. Animals infected with sporozoites from the Tecojate strain presented a patent period of 21-32 days whereas parasitemia appeared between days 19-53 in monkeys infected with sporozites from Cartagena strain. Persistence of RNAi-Mediated Knockdown in Drosophila Complicates Mosaic Analysis Yet Enables Highly Sensitive Lineage Tracing. Pleuropulmonary blastoma (PPB) is an aggressive embryonal malignancy presenting in early childhood, presumably arising from pleuropulmonary mesenchyme. Single-center study on transplantation of livers donated after cardiac death: A report of 6 cases. The purpose of this study was to investigate whether colours other than black and white have similar effects on words related to morality and to determine the time course of these effects. The multinational prospective study on the efficacy of conservative chemotherapy and surgical treatment coordinated by the Medical Research Council has just completed a final 15-year follow-up report. Subclavian artery-esophageal fistula after placement of a self-expanding metal stent in a patient with esophagogastric anastomosis stenosis. High Current Ionic Diode Using Homogeneously Charged Asymmetric Nanochannel Network Membrane.

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As PDT lesions in the gastrointestinal tract heal so well, the technique is suitable for repeated endoscopic use. These marks were photographed and assessed by six observers before and after the application of chlorhexidine skin preparation. Evaluation of renal adverse effects of combination anti-retroviral therapy including tenofovir in HIV-infected patients. After opacification of the cisterna chyli (CC) with pedal lymphography, the CC is punctured transabdominally with a 21-gauge needle and the TD is catheterized with a 3-F catheter over a guide wire. We present a unique case of ipsilateral stroke in a 55-year-old right-handed hypertensive man with proven uncrossed pyramidal tract demonstrated by tractography. Once the preosteocytes/osteocytes leave lacunae, they can dedifferentiate, potentially providing an zyrtec treat sinus infection additional source of functional osteoblasts. The RFLP method described should prove useful in examining strains for such mutations. In children with acute lymphoblastic leukemia (ALL), the hydration is commonly initiated 4 hours before start of the methotrexate (MTX) infusion. Epoetin alfa, 150 U/kg, or a matching volume of placebo was administered subcutaneously three times per week for 6 weeks.

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Melanoplus sanguinipes entomopoxvirus encodes a similar protein, but SFV is the first mammalian virus potentially capable of photoreactivating ultraviolet DNA damage. Decades prior she had undergone a surgery for the excision of a large schwannoma. The viability of Saccharomyces cerevisiae in biocompatible polymers under different growth conditions and studied using time-resolved fluorescence techniques is presented. This paper believes that the use of the tape could enhance pediatric health care in situations, wherein weighing them is impossible. Correlations of nucleotide substitution rates and base composition of mammalian coding sequences with protein structure. controls and the prevalence of colonization in patients were pooled using the random-effects model. Probiotic Gut Microbiota Isolate Interacts with Dendritic Cells via Glycosylated Heterotrimeric Pili.

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MiR-21 is an oncomir expressed by malignant cells and/or tumor microenvironment components. Maternal Pumilio acts together with Nanos in germline development in Drosophila embryos. To date, the molecular mechanisms underlying these pathogenic events are poorly understood. Preparation of hollow nickel silicate nanospheres for separation of His-tagged proteins. This study found that there are 2 clearly distinctive reasons for self-referral to the ED: health concerns or practical motives. Such increases in ADO are not dependent on a beta 1-adrenoceptor-mediated mechanism. ESkine, a novel beta-chemokine, is differentially spliced to produce secretable and nuclear targeted isoforms. This model suggests that the activation of autoimmunity by environmental factors is probably facilitated by genetic background, and might partly explain the diversity of autoimmune manifestations in D-PEN-treated patients. The endothelial cells of the two species produced significant amounts of IFN in response to various viruses and poly (I) poly (C).

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