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Urobactrim (Trimethoprim)

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This medication is a combination of two antibiotics: sulfamethoxazole and trimethoprim. It is used to treat a wide variety of bacterial infections (such as middle ear, urine, respiratory, and intestinal infections). It is also used to prevent and treat a certain type of pneumonia (pneumocystis-type). This medication treats only certain types of infections. It will not work for viral infections (such as flu). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.

Other names for this medication:
Actrim, Anitrim, Avlotrin, Bacsul, Bacta, Bactelan, Bactipront, Bactropin, Bascul, Cotreich, Dhatrin, Ditrim, Dotrim, Eliprim, Erphatrim, Forcrim, Groprim, Ifitrim, Ikaprim, Kaftrim, Letus, Metrim, Momentol, Neotrim, Nufaprim, Omsat, Organosol, Ottoprim, Primazole, Purbac, Sigaprim, Sitrim, Sulfatrim, Sulfoid, Sulphax, Supreme, Tabrol, Trimecor, Trisulfose, Trisulin, Trizole, Urisept, Vanadyl

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Also known as: Trimethoprim


Bactrim contains a combination of sulfamethoxazole and trimethoprim. Sulfamethoxazole and trimethoprim are are both antibiotics that treat different types of infection caused by bacteria.

Bactrim is used to treat ear infections, urinary tract infections, bronchitis, traveler's diarrhea, shigellosis, and Pneumocystis jiroveci pneumonia.


Adults: The usual adult dosage in the treatment of urinary tract infections is 1 Urobactrim DS (double strength) tablet or 2 Urobactrim tablets every 12 hours for 10 to 14 days. An identical daily dosage is used for 5 days in the treatment of shigellosis.

Children: The recommended dose for children with urinary tract infections or acute otitis media is 40 mg/kg sulfamethoxazole and 8 mg/kg trimethoprim per 24 hours, given in two divided doses every 12 hours for 10 days. An identical daily dosage is used for 5 days in the treatment of shigellosis.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include loss of appetite, vomiting, fever, blood in your urine, yellowing of your skin or eyes, confusion, or loss of consciousness.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Side effects

The most common side effects associated with Urobactrim are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Urobactrim is contraindicated in patients with a known hypersensitivity to trimethoprim or sulfonamides, in patients with a history of drug-induced immune thrombocytopenia with use of trimethoprim and/or sulfonamides, and in patients with documented megaloblastic anemia due to folate deficiency.

Urobactrim is contraindicated in pediatric patients less than 2 months of age. Urobactrim is also contraindicated in patients with marked hepatic damage or with severe renal insufficiency when renal function status cannot be monitored.

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