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Thorazine (Chlorpromazine)

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Thorazine is a psychotropic agent indicated for the treatment of schizophrenia. It also exerts sedative and antiemetic activity. Thorazine has actions at all levels of the central nervous system-primarily at subcortical levels-as well as on multiple organ systems.

Other names for this medication:
Chlorpromazine, Clozine, Megatil, Serectil

Similar Products:
Glucotrol, Celebrex, Detrol, Prevacid, Imdur, Amethopterin, Sovaldi, Hytrin, Zovirax

Also known as: Chlorpromazine


Generic Thorazine is an effective preparation developed by medical scientists to treat certain mental or mood disorders (eg, schizophrenia), the manic phase of manic-depressive disorder and severe behavioral problems in children. Generic Thorazine is also used to control nausea and vomiting, nervousness before surgery, and hiccups that will not go away. Generic Thorazine can be used to treat episodes of porphyria and in combination with other medicines to treat tetanus. Generic Thorazine is an anti-psychotic medication in a group of drugs called phenothiazines. Generic Thorazine works by changing the actions of chemicals in your brain. Generic Thorazine may also be used for other purposes. Generic name of Generic Thorazine is Chlorpromazine. Brand name of Generic Thorazine is Thorazine.


Take Generic Thorazine by mouth with a glass of water. Take Generic Thorazine at regular intervals. Do not take it more often than directed. Do not take Generic Thorazine in large amounts. If you want to achieve most effective results do not stop using Generic Thorazine suddenly.


If you overdose Generic Mellaril and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Thorazine overdose: dry mouth, constipation, bloating or stomach cramps, feeling restless or agitated, fever, seizure, muscle stiffness, jerky muscle movements, changes in heart rate, extreme drowsiness, and fainting.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Thorazine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Generic Thorazine if you are allergic to Generic Thorazine components, or other phenothiazines such as fluphenazine (Permitil), perphenazine (Trilafon), prochlorperazine (Compazine, Compro), promethazine (Adgan, Pentazine, Phenergan), thioridazine (Mellaril), or trifluoperazine (Stelazine). Do not take Generic Thorazine if you're pregnant or you plan to have a baby, or you are a nursing mother. Do not use Generic Thorazine in psychotic conditions related to dementia. Do not use Generic Thorazine if you have brain damage, bone marrow depression, or are also using large amounts of alcohol or medicines that make you sleepy. Be very careful with Generic Thorazine if you have liver or kidney disease, heart disease or high blood pressure, glaucoma, severe breathing problems, past or present breast cancer, low levels of calcium in your blood, adrenal gland tumor, enlarged prostate or urination problems, a history of seizures, Parkinson's disease. Do not take Generic Thorazine together with: atropine (Atreza, Sal-Tropine); lithium (Eskalith, Lithobid); phenytoin (Dilantin); an antibiotic; birth control pills or hormone replacement estrogens; blood pressure medication; a blood thinner such as warfarin (Coumadin, Jantoven); certain asthma medications or bronchodilators; incontinence medications; insulin or diabetes medications you take by mouth; medication for nausea, vomiting, or motion sickness; medications to treat or prevent malaria; medications used for general anesthesia; medicines used to prevent organ transplant rejection; numbing medicine such as lidocaine or Novocain; a stimulant or ADHD medication; ulcer or irritable bowel medications; or medicines to treat Parkinson's disease, restless leg syndrome, or pituitary gland tumor (prolactinoma). Avoid temperature extremes, such as saunas, hot tubs, or very hot or cold baths or showers. Dress warmly in cold weather. Avoid using other medicines that make you sleepy while using Generic Thorazine. Be careful if you drive or do anything that requires you to be awake and alert while using Generic Thorazine. Avoid exposure to sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Avoid drinking alcohol. It can be dangerous to stop Generic Thorazine taking suddenly.

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Case-control analysis of allogeneic bone marrow transplantation versus maintenance chemotherapy for relapsed ALL in children. Four patients had a very low titre and the remaining had no detectable neutralizing antibodies at all. Optimal activation of endothelial cells by nanomolar quantities of endotoxin (lipopolysaccharide, LPS) requires the presence of plasma or serum. When donor and recipient genotypes are not identical, the risk of GVHD increases. Novel aromatic isothiouronium derivatives which act as high affinity competitive antagonists of alkali metal cations on Na/K-ATPase. The extent of secretory vesicle swelling dictates the amount of intravesicular contents expelled during secretion. Identification of Moraxella-like bacteria isolated from caprine and ovine nasal flora. Massage and probing may have good results even in children older than 3 years. Fibroblasts cultured within collagen gels showed similar growth rates, an increased production of collagen but reduced levels of hyaluronan synthesis in comparison to cells in monolayer culture.

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This report describes trends of ORS reported during four consecutive seasons 2000, 2001, 2002 and 2003 in the province of Quebec, Canada. This method may be useful for quality control in the production of adenoviral vectors free of wild-type virus for gene therapy applications. A prospective multicenter study of obstetric practices was conducted in three developing countries (Benin, Congo and Senegal) to analyze oxytocic use during labor. To accomplish this, the animals were treated with heparin 150 units or 300 units twice daily following microvascular repair using standard microsurgical techniques. In order to further explore the molecular basis for G1 cyclin action, we used cell lines capable of expressing cyclin D1, E, or both prematurely and measured the effect of cyclin expression in early G1 on phosphorylation of the retinoblastoma susceptibility gene product (pRb). Telecommunication networks that link medical information with the community can support home caregivers while providing skills training and crisis intervention to prevent unnecessary hospitalization. Analysis of the additional Fc gamma RIIIa2-4 transcripts suggests the expression of novel, as yet unknown Fc gamma RIII receptor isoforms on NK cells. Eleven non-diabetic COPD patients were included in the study and equal number of age and sex-matched healthy individuals were enrolled as controls.

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Spatial patterns of protein expression in focal infections of human cytomegalovirus. Amyloid beta (A beta) immunoreactivity has been demonstrated in all extracellular neurofibrillary tangles (E-NFT) and most intraneuronal neurofibrillary tangles (I-NFT). It is surprising that the cerebellum, implicated more than 40 years ago, has not been reevaluated for its role in motion sickness in view of the explosion of new data on this structure. When expressed in COS-1 and Chinese hamster fibroblast (CHW) cells, the protein was shown to possess both transmembrane and GPI anchors, indicating that a cleavable N-terminal signal peptide is not a prerequisite for the biosynthesis of GPI-anchored proteins. Mutations in at least four loci can cause FHC: chromosomes 14q1 (beta cardiac myosin heavy chain gene), 1q3, and 15q2 and another unidentified locus, suggesting substantial genetic heterogeneity. Clorgyline stimulated pineal melatonin biosynthesis in both lines of rats. However, we have observed that submucosal fat deposition can occur in a short period of time. The idea is to give the cytostatic drugs at times of the day when optimal effect on the tumor is achieved, but at the same time causing minimal toxic side effects. In the present study, we demonstrate for the first time that activated Ras can activate ErbB4 receptor in a ligand-independent manner.

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The prevalence of enterobiasis among the boarding-school pupils in the city of Ufa. Transscleral laser photocoagulation was applied under indirect ophthalmoscope visual control with indentation of the sclera by the laser probe. Patients with less severe disabilities have an increased functional status with improved nutrition. This study was undertaken to evaluate the effects of cyclosporin A on prostanoid (prostaglandin and thromboxane) production by human decidua. Mice lacking the epsilon-subunit gene die prematurely, showing that the adult type is essential for maintenance of neuromuscular synapses in adult muscle. Lower numbers imply an additional process, possibly transformation of complex into neutral lipids. The current flowing through these junctions can be controlled by adjusting the potential applied at the electrodes with respect to the redox potential of the species by using an electrochemical system. The two sets of transmembrane helices of mammalian adenylyl cyclases are thus not necessary for the catalytic or the most characteristic regulatory activities of the enzyme. The horse deteriorated neurologically over the next 24 hours and was euthanased on humane grounds. Epitope mapping experiments using truncated IL-3R alpha-chain mutants and IL-3R alpha/GM-CSFR alpha chimeras revealed that 31 amino acids in the N-terminus of IL-3R alpha were required for MoAb 7G3 binding.

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The overall pattern of up-regulated genes indicated triggering of the proinflammatory process. Increase in cardiovascular survival leads to a further increase in major stroke prevalence among the oldest age groups. Despite a phagocytosis-related enhancement of NO2- release, reactive nitrogen intermediates (RNI) are not directly involved in the bactericidal mechanism, as revealed by increased intracellular killing owing to RNI inhibitors. The EG of slow-fast AVNRT is relatively wide, as demonstrated by single atrial extrastimulation from the interatrial septum near the AV junction. A clinical trial using the anti-depressant nomifensine in Parkinsonism is reported. A high alcohol intake is significantly associated with diseases of the gastrointestinal tract, but less is known about the effects of moderate consumption, specifically moderate average volume of alcohol consumption. The pathological anatomy of the arteries, capillaries and vascular tumors of the fetus and newborn infant.

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The VFLs on each side and the vertical differences between the vocal folds were calculated. A simple high-performance thin-layer chromatographic (HPTLC) method has been developed for the simultaneous determination of the pharmacologically important quinazoline alkaloids vasicine and vasicinone in Adhatoda vasica. Adoptive transfer of experimental allergic neuritis in the immune suppressed host. The basal caloric production of 541 subjects of both sexes between 40 and 91 years of age. There are approximately 43 species of trematodes which man acquires from eating improperly cooked fish, frogs, or crustaceans. It is hoped that the advice will make the challenge of night shift work not only easier to tolerate, but also safer for both hospital patients and their doctors.

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The influence of race and phenotype on the erythrocyte D antigen studied by I-131-labeled anti-D. Diagnosis of silicone gel breast implant rupture by ultrasonography. Three forms of DNA polymerase, named enzymes A, B, and C, that preferred (rA)n x (dT)12-18 as a template-primer, were partially purified from an extract of rat spleen. The orientation column exhibits spontaneous collective oscillations in activity in response to suitable visual stimuli. While sensitivity to nitrogen mustard of the mutant at 36 degrees C is very similar to that of the non-leaky allele snm1-1, multi-copy vector-mediated overexpression of snm1-2ts leads to a significantly reduced sensitivity to nitrogen mustard. Absorption, circular dichroism, fluorescence, and electron paramagnetic resonance spectra of mutant T54S show that this substitution has no influence on the formation and stability of the ferredoxin. The present extended thermodynamic approach is able to predict and explain why the purely electrostatic approach works better for lower analyte lipophilicity or higher organic modifier concentration. Moreover, FAS1 domains such as fastatin may be developed into drugs for blocking tumor angiogenesis. The glucocorticoid-induced receptor (GIR) is an orphan G-protein-coupled receptor awaiting pharmacological characterization.

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In vitro percutaneous absorption of all-trans retinoic acid applied in free form or encapsulated in stratum corneum lipid liposomes. Attainment of these goals will lead to a better understanding of the peroxisome biogenesis disorders, their pathophysiology and treatment. Seasonal intermittent preventive treatment with artesunate and sulfadoxine-pyrimethamine for prevention of malaria in Senegalese children: a randomised, placebo-controlled, double-blind trial. Basing antibiotic therapy solely on quantitative BAL cultures is efficacious in trauma patients. Forty-five patients with a suspected sternal fracture were examined radiographically and sonographically.

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Furthermore, the regional apparent diffusion coefficient (ADC) had already decreased significantly in both the gray and white matters of the ischemic lesion 4 h after onset, even though hyperintensity was not visible in the white matter on the DWI. A very gradual decrease occurred in vivo in the dry weight of the bars over the period of the study (up to 18 weeks). A second weaker hybridization signal also found on chromosome 17q11 and results obtained by Southern blot analysis suggest that the entire PYY-PPY region has undergone a further duplication event. Using this parametrization, a practical method has been provided for determining the transfer function between each loudspeaker and every point in the reproduction region. The negative results in pilocytic astrocytomas are in line with the benign course of these tumors, whereas for malignant gliomas no difference seems to exist in comparison with adult cases. The protein behaves as a monomer and refolds with a transient on-pathway folding intermediate. Instead, they demonstrate that the RCI proteins are highly homologous to a family of proteins, known as 14-3-3 proteins, which are thought to be involved in the regulation of multifunctional protein kinases. Symptoms of asthma occur as a direct or indirect result of many contributing factors, including influences from the natural and built environments, human behavior, and the adequacy of techniques used in its management.

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In addition, the tramadol 50 mg tablets interaction program can handle images and sound to present pictures and relevant information on the identified parasites. In HUVE, the topoisomerase II selective inhibitors novobiocin, nalidixic acid, and etoposide prevented cytokine-induced VCAM-1 surface expression, but not E-selectin or ICAM-1 surface expression. NMR microspectroscopy using 100 microns planar RF coils fabricated on gallium arsenide substrates. To alter the substrate specificity of the biphenyl dioxygenase (BphA) of Burkholderia xenovorans LB400, we applied a directed evolution approach that used structure-function relationship data to target random mutageneses to specific segments of the enzyme. Ultrasound guided fine needle aspiration cytology (FNAC) showed caseating granulomatous inflammation. This is the first molecularly characterized interstitial deletion in a patient with the clinical features of Jacobsen syndrome. A simple plasma spraying method was employed in coating hydroxyapaptite (HA) on to carbon/carbon composites (C/C composites). Monitoring development and pathology of Drosophila indirect flight muscles using green fluorescent protein. Our results demonstrate that sodium salicylate reversibly attenuates the GABA(A) response of dorsal horn neurons, suggesting that GABA(A) receptors in the region are pharmacological targets of sodium salicylate.

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TGF-alpha, in particular, has been implicated as an autocrine growth factor for several cancer cell lines. Patterns of cytokine mRNA in Trichinella spiralis infected rats. Autoradiographic study of supravital DNA synthesis in fetal human brain. Based on the physiological distinctions between P and M systems, the use of isoluminant color patterns and apparent motion display allows us to evaluate P and M systems, respectively. The strain was characterized with respect to its physiological and chemotaxonomic properties. CNTs carrying neutral electric charge sustained the highest cell growth and production of plate-shaped crystals. Cultures of five strains of Mycoplasma hyopneumoniae (syn, M suipneumoniae) were each inoculated intravenously into four pigs aged eight to nine weeks. Anti-NKH-1 antibody recognizes an isoform of the neural cell adhesion molecule (N-CAM) that is cleocin dosage oral involved in cell-cell interactions during embryonic stages and has been detected in skin autonomic nerves. Genetic conditions and the scope of the Americans with Disabilities Act.

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However, many of the commercial vectors encoding different solubility tags require different cloning and purification steps for each vector, considerably slowing down expression screening. They show initially activation of acute-phase response genes and accumulation of alpha 2- and beta-globulins in the plasma, which is followed by polyclonal hypergammaglobulinemia. The amount of insoluble mucus of the large intestine was also increased in the CF mice, an effect that was partially restored in the CF/Muc1-/- mice. The Parallel Rural Community Curriculum (PRCC) was developed by Flinders University, South Australia, in 1997 to enable senior medical students to undertake an entire clinical generic protonix side effects patient reviews year based in rural general practice in the Riverland region of South Australia. The literature suggests that patients may be categorized as having one form of the disorder or the other. This study aims to document the psychometric characteristics of the translation to Spanish of the gastrointestinal symptoms rating scale (GSRS) and quality of life in reflux and dyspepsia (QOLRAD). Psychiatric staff investigate the psychology of a nation, its desires, anxieties and defense and they recognize their role. Native pig pepsin was analysed by negative ion electrospray mass spectrometry in order to rationalize anomalies between the published sequences.

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In human studies, activation of CB1 receptors by cannabis or its active ingredient, Delta9-tetrahydrocannabinol (THC), has modest and inconsistent effects on BP. Rorschach rigidity and sensory decrement in a senescent population. The data indicate that glomerular beta 1 integrin expression is altered in a manner that would promote cell adhesion to the matrix proteins known to accumulate in this disease model. The mechanisms underlying resistance to hormones in preclinical model systems remain under intense investigation. It is concluded that pituitary adenosine is a trophic factor for hypothalamic dopaminergic neurons. The diagnosis of acute exacerbations is based on clinical observations of sputum production, cough and dyspnoea. A seven-year-old boy with a retrovesical diverticulum and ipsilateral renal dysplasia is reported.

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Thus, large HR was observed in some patients in response to helminth antigens despite low levels of both specific and total IgE content in plasma. Use of viscosigens to stabilize vitamin B12 solutions against photolysis. Clonidine in oral doses of 150 to 900 micrograms/day decreased average mean blood pressure 18.6 mm Hg (p less than 0.01), average heart rate 16.4 bpm (p less than 0.01), limb blood flow 1.63 ml/100 gm . The mechanisms of action and binding affinities of noncompetitive antagonists differ among nicotinic receptor subtypes. We further show that Drosophila FOXO is not required for normal salivary gland death and that the rescue of salivary gland death by PI3K occurs independent of FOXO. Instead, these data suggest an inverse relationship between moderate alcohol consumption and the risk of renal dysfunction.

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From the present study, it is suggested that disruption of the fodrin network may occur in association with the process leading to mast cell degranulation. On the problem of Besnier-Boeck-Schaumann disease in recent years (1954-58 zantac generic drugs ). Tallimustine shows strong selectivity by decreasing only correctly initiated transcripts. The geometry of amfenac in neutral and anionic form was totally optimized, starting from standard geometries and crystallographic data, using semiempirical AM1 and MNDO quantum-mechanical methods. Results on the reliability of the method and values for nine Finnish omnivorous and nine vegetarian women are presented. Nanomolar concentrations of leukotriene C4 and phorbol 12-myristate acetate, a protein kinase C activator, stimulated endothelin-1 release by vascular endothelial but not smooth muscle cells. The upper limit of hearing may serve as clinically useful information on the hearing impairment that precedes noticeable hearing impairment in conventional audiometry for workers exposed to intensive occupational noise. Five patients with therapeutically refractory tinnitus were selected for this study. On the development of various chronic liver diseases after peri-hepatic artery neurectomy operation.

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Several forces have resulted in the creation in Tayside of the first formally integrated unit of undergraduate and postgraduate education in general practice in the United Kingdom. A total of 437 sera were positive and 67 negative (ie, less than 1:20 titer). Four cases of VC and five cases of PSCC of larynx in our hospital between 1991 approximately 2003 were studied retrospectively, the clinical and pathology character of VC and PSCC were observed. Mortality from cancer of the cervix uteri in British Columbia and other parts of Canada. Pineal NPY contents fell during the night in long-day animals and were relatively constant in short-day hamsters. These benefits continued through the mean survival period after stenting of 134 days (range, 2 to 799 days). We have combined the strength of our synthetic combinatorial library approach for the rapid identification of highly active compounds with prior knowledge of the relationship between the antimicrobial activities of individual peptides with specific induced conformations in order to identify new peptides with enhanced activity relative to a starting known antimicrobial sequence. This formulation relieved climacteric symptoms, and did not adversely affect lipids and clotting factors, except for a slight increase in serum triglycerides.

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Neonatal erythrocytic pathology caused by glucose-6-phosphate dehydrogenase deficiency. Artificial induction of the acrosome reaction in human spermatozoa. We showed that the immunoblot technique is a sensitive and quantitative alternative to radioligand binding assays. Future measures include conducting a sero- prevalence survey to determine the feasibility of Hepatitis A immunization to the susceptible population in this area. The beta 1-integrin (CD29) receptors: mediators of T lymphocyte--extracellular matrix recognition that affect adhesion, activation and lymphokine secretion. Creating separate categories for age ranges 85 to 89, 90 to 94, 95 to 99, and 100 and older suggests different incidence patterns for a variety of cancers, including mammary carcinoma in situ (CIS).

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Persistent physiological vascular reactions are formed (within the upper normal range). It can provide remarkable help for local injection therapy and for planning surgery because of its suitability for evaluation of the extent of rheumatoid disease. These position-specific results are compared with the average values usually used for radiation protection purposes. The supporters of bone density measurement or osteodensitometry claim that it is possible to reduce the frequency of fractures if a lack of systemic bone mineral content is detected in time. The findings were compared with those for seven small cell lung carcinomas. Pilot evaluations in medical, dentistry and pharmacy courses shows that students regarded Web-SP as easy to use, engaging and to be of educational value. A pooled analysis of seven randomized crossover studies of the palatability of cefdinir oral suspension versus amoxicillin/clavulanate potassium, cefprozil, azithromycin, and amoxicillin in children aged 4 to 8 years. Studies of the organization of double-stranded DNA within bacteriophage heads during the past four decades have produced a wealth of data. Their HPRT enzyme activity was slightly lower than that of normal controls. Renin angiotensin agents are the most efficacious of therapies available at this time.

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Hyperthermia is particularly effective against some cells, such as those in late S-phase, that are resistant to radiation therapy. Health care workers need a better understanding of the barriers patients face and why patients may choose to remain in abusive relationships, even in the absence of economic or health limitations. Treatment of obesity with a new anorexiant, diethylpropion, without special stress on diet. Our aim was to test the hypothesis that nocturnal increases in antral pH are due solely to DGR. Although the available literature suggests that cytogenetic abnormalities cause some cases of schizophrenia, these abnormalities must account for only a small fraction of all schizophrenia. In previous studies of this laboratory, epitope (site contacts with TCR) and agretope (site contacts with MHC molecule) were determined on p43-58 peptide composed of residues 43 to 58 of pigeon cytochrome c. Vesicular cycling increased markedly during glutamate-induced long-term potentiation.

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The incidence of pure red cell aplasia (PRCA) in patients with chronic kidney disease associated with the subcutaneous (s.c.) administration of epoetin alfa (EPREX) began to increase in 1998. Asbestos-induced injury to cultured human pulmonary epithelial-like cells: role of neutrophil elastase. Galactomannans from Brazilian seeds: characterization of the oligosaccharides produced by mild acid hydrolysis. The percentage of children who aroused in response to acoustic stimuli, and the arousal threshold (i.e., sound level at which arousal occurred), were compared between groups and sleep stages. The SP-mediated suppression of BPO-specific memory IgE responses appeared to involve interferon gamma (IFN gamma). Tuberculous dactylitis of the thumb, mediastinal and left hilar lymphadenopathy, and probable left cervical lymphadenopathy.

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