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Sustiva

Sustiva works by preventing the HIV virus from multiplying in your body. It helps control the infection and makes your immune system work better. This lowers your chances of getting complications such as new infections and improves your quality of life.

Other names for this medication:
Cytocom, Duovir, Efavir, Efavirenz, Efcure, Efferven, Emduo, Estiva, Evirenz, Lamivir, Lazid, Odivir, Retrodel, Revenz, Tenola, Trioday, Trustiva, Viraday, Viranz, Virocmb, Virolis, Vonavir, Zidolam

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Also known as: Efavirenz

Description

Sustiva (efavirenz) is an antiviral medicine that prevents human immunodeficiency virus (HIV) from multiplying in your body.

Sustiva is used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS).

Sustiva is for adults and children who are at least 3 months old and weigh at least 8 pounds. This medicine is not a cure for HIV or AIDS.

Dosage

Usual Adult Dose for HIV Infection:

600 mg orally once a day Comments: -This drug should be used with a protease inhibitor and/or NRTIs. Use: In combination with other antiretroviral agents, for the treatment of HIV-1 infection

Usual Adult Dose for Nonoccupational Exposure:

US CDC recommendations: 600 mg orally once a day Duration of therapy: 28 days Comments: -This drug should be used with (lamivudine or emtricitabine) plus (zidovudine or tenofovir); recommended as the preferred NNRTI-based regimen for nonoccupational postexposure prophylaxis of HIV infection. -Prophylaxis should be started as soon as possible, within 72 hours of exposure. -Not approved by US FDA.

Usual Adult Dose for Occupational Exposure:

US Public Health Service working group recommendations: 600 mg orally once a day Duration of therapy: 28 days, if tolerated Comments: -An alternative antiretroviral agent for use as HIV postexposure prophylaxis only with expert consultation -Prophylaxis should be started as soon as possible, preferably within hours after exposure. -The optimal duration of prophylaxis is unknown and may differ based on institution protocol. -The most current therapeutic guidelines should be consulted for more information. -Not approved by US FDA.

Usual Pediatric Dose for HIV Infection:

3 months or older: 3.5 to less than 5 kg: 100 mg orally once a day 5 to less than 7.5 kg: 150 mg orally once a day 7.5 to less than 15 kg: 200 mg orally once a day 15 to less than 20 kg: 250 mg orally once a day 20 to less than 25 kg: 300 mg orally once a day 25 to less than 32.5 kg: 350 mg orally once a day 32.5 to less than 40 kg: 400 mg orally once a day 40 kg or more: 600 mg orally once a day Use: In combination with other antiretroviral agents, for the treatment of HIV-1 infection

Detailed Sustiva dosage information

Overdose

If you overdose Sustiva and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Sustiva are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Sustiva if you are allergic to Sustiva components. Do not take Sustiva if you are pregnant, planning to become pregnant, or are breast-feeding. It is unknown if Sustiva is excreted in breast milk. Avoid breast-feeding because breast milk can transmit HIV. Be careful with Sustiva if you have mental disorders, liver disease (such as hepatitis). Avoid machine driving. Limit alcohol intake, as it may intensify drug side effects. It can be dangerous to stop Sustiva taking suddenly.

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