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Sildenafila (Sildenafil)

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Sildenafila is a brand name of a synthetically produced agent called Sildenafil. It was discovered in the early 2000s as a medicine for the treatment of erectile disorders in men. Clinical trials proved its safety and efficiency, and the drug was launched into the market under the name of Viagra. Its principle of action is similar to all existing medicines relating to the family of PDE-5 inhibitors. Sildenafil speeds up the blood flow in the pelvic area by making vessels relaxed, thus providing a better penile blood supply and causing a firmer erection. Later on it was discovered that Viagra can be also used for relieving symptoms of benign prostatic hyperplasia. It stimulates fluid circulation providing its efflux from the prostate gland.

Other names for this medication:
Caverta, Intagra, Kamagra, Penegra, Revatio, Silagra, Sildenafil, Sildenafila, Sildenafilo, Sildenafilum, Sildigra, Suhagra, Veega, Zenegra

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Also known as: Sildenafil


Sildenafil citrate was the first medicine formulated for the treatment of male impotence in the year 1998 by the researchers of drug manufacturing company Pfizer. The drug is also used for the treatment of the pulmonary arterial hypertension which is rare pulmonary disorder that occurs in mountaineers and people living at high altitude.

Millions of individuals visit their doctors after suffering from erectile dysfunction or male impotence. The doctors will look after the individual's health record for all the ailments and give out best possible treatment. Most of the individuals are prescribed with sildenafil citrate for the cure of impotence. This is the 1st line of treatment opted by all the physicians in case of impotence in men.

People who cannot get proper erection is on sexual stimulation needed sildenafil 100mg. This medicine will help in improvement of blood flow to the muscles of penis. As the blood flow increases owing to sexual stimulation and erection takes place, the man can indulge into sexual activity and perform to satisfaction. This medicine has helped millions of individuals to save their relationships that would have been devastated because of impotence.


For most patients, the recommended dose is 50 mg taken, as needed, approximately 1 hour before sexual activity. However, VIAGRA may be taken anywhere from 30 minutes to 4 hours before sexual activity.

The maximum recommended dosing frequency is once per day.

Based on effectiveness and toleration, the dose may be increased to a maximum recommended dose of 100 mg or decreased to 25 mg.

VIAGRA may be taken with or without food.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Sildenafil is contraindicated in patients with a known hypersensitivity to any component of the tablet or injection. The safety and efficacy of combinations of sildenafil with other treatments for erectile dysfunction have not been studied. Therefore, the use of such combinations is not recommended.

The use of sildenafil is not recommended in patients with pulmonary veno-occlusive disease (PVOD). Administration of sildenafil in this population may significantly worsen cardiovascular status. In addition, if signs of pulmonary edema occur during sildenafil administration, the possibility of associated PVOD should be considered.

Sildenafil is contraindicated in patients who are currently on nitrate/nitrite therapy (see Drug Interactions). Consistent with its known effects on the nitric oxide/cGMP pathway, sildenafil was shown to potentiate the hypotensive effects of organic nitrates and nitrites. Patients receiving nitrates in any form are not to receive sildenafil. This includes any patient who receives intermittent nitrate therapies. It is unknown if it is safe for patients to receive nitrates once sildenafil has been administered.

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Effect of Perceived Politics and Perceived Support on Bullying and Emotional Exhaustion: The Moderating Role of Type A Personality. We report the novel finding that upper body exercise increases lower extremity venous blood flow in healthy volunteers and in acute DVT patients. The main objective of this study was to assess the knowledge and attitude among Pharmacy students of the University of Prishtina in regards to the antibiotics. Both groups received fluticasone propionate nasal drops twice daily for 12 weeks after initial treatment. In addition, abrogation of anti-Fc reactivity was observed when affinity-labelled MoAbs were used as coating antigens in solid-phase ELISAs.

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DIFFUSE INTERSTITIAL PULMONARY FIBROSIS: A VISCERAL MANIFESTATION OF A NUMBER OF DISEASES OF DIVERSE NATURE. The object of this study was to conduct and analyze the output of a survey involving a cohort of all Italian hospitals performing thoracic surgery to gather data on anesthetic management, one-lung ventilation (OLV) management, and post-thoracotomy pain relief in thoracic anesthesia. The first case was a colonic fistula for cecal defect, surgical intervention was carried out because treatment during 14 days with hormonal treatment after the third consecutive day of somatostatin application. THE EFFECT OF GLUCOSE PRETREATMENT ON THE ANTI-TUMOUR ACTION OF MANNITOL MYLERAN. Mcm1 is required to coordinate G2-specific transcription in Saccharomyces cerevisiae. Our results add to evidence for a negative impact of RRMS on HRQoL and they demonstrate the benefits of BG-12 on HRQoL measures, which coupled with significant clinical efficacy, further support its use as a new treatment for RRMS. Results of this pre-planned meta-analysis in elderly patients with diabetes demonstrate a significant reduction in hypoglycaemic events with IDeg relative to IGlar. 16S rRNA gene-based identification of bacteria in postoperative endophthalmitis by PCR-Denaturing Gradient Gel Electrophoresis (PCR-DGGE) fingerprinting.

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Purification, crystallization, and preliminary X-ray characterization of a 36 kDa amaranth globulin. Percutaneous coronary intervention (PCI) for anomalous left coronary artery (LCA) originating from the noncoronary cusp (NCC) is challenging, as it poses difficulties with the engagement of the guiding catheter and the establishment of backup support. The reasoning why axillary dissection is still the gold standard in breast cancer management is explained and related to the other methods of axillary assessment and therapy. The levels of glutamate and homocystein are increased in autism while the levels of glutamine and tryptophan are decreased. ON THE SURGICAL TREATMENT OF OSTEOCHONDROSIS DISSECANS OF THE HIP JOINT. The aim of the work was to investigate the effect of pharmacological blockade and activation of brain MC receptors on food intake under stress. In 170 participants, plasma levels of miR-29a were assessed by quantitative real-time polymerase chain reaction (qRT-PCR) while plasma ox-LDL levels were determined using enzyme-linked immunosorbent assay (ELISA) kits. Cardio-Oncology: An Update on Cardiotoxicity of Cancer-Related Treatment.

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A total of 707 endosonographers were contacted and asked to complete an online survey encompassing both demographic and practice data. None of the patients, irrespective of group, had returned to their pre-injury level of activity. Tumor stiffness was quantitatively measured by shear-wave elastography in preoperative ultrasound examination, calculated as mean elasticity value (kPa). The structure described here establishes the fundamentals for a better understanding of the mechanism ruling events such as prohormone processing and will enable modelling of regulatory carboxypeptidases as well as a more rational design of inhibitors of carboxypeptidase D. In clones which were recovered in the distal domain, different effects were seen dependent on position with respect to the dorsal-ventral axis. The effect of NA on fluidity may be attributed to a mechanical interaction of the drug molecules with the lipid molecules. In mammals, structures and functions of various TRAPP complexes are beginning to be understood. A two-exponential behavior for the spin-lattice relaxation was observed with the appearance of denatured collagen.

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