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Requip (Ropinirole)

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Requip works well to treat Parkinson's disease or restless legs syndrome. The immediate-release tablet can be used for both conditions, whereas the extended-release tablet is only approved for Parkinson's disease.

Other names for this medication:
Parkirop, Ropark, Ropeway, Ropin, Ropinirole, Ropitor

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Also known as: Ropinirole


Generic Requip is an anti-Pakirson medication. Generic Requip is used to treat symptoms of Parkinson's disease such as stiffness, tremors, muscle spasms, poor muscle control. Requip is also known as Ropinirole, Ropidon, Adartrel, Ropark. Generic Requip is also used to treat restless legs syndrome (RLS). Generic Requip has some of the same effects as a chemical called dopamine, which occurs naturally in your body. Low levels of dopamine in the brain are associated with Parkinson's disease. Generic name of Generic Requip is Ropinirole. Brand names of Generic Requip are Requip, Requip XL.


Usual Adult Dose of Requip for Parkinson's Disease:

Immediate-release tablets: Initial: 0.25 mg orally three times daily After 1 week, the dose may be titrated up in weekly increments based on individual efficacy and tolerability: Week 2: give 0.5 mg orally 3 times daily Week 3: give 0.75 mg orally 3 times daily Week 4: give 1 mg orally 3 times daily After week 4, increase by 1.5 mg/day on a weekly basis up to a dose of 9 mg/day, then increase by 3 mg/day on a weekly basis up to a maximum daily dose of 24 mg Maximum Dose: 8 mg orally three times a day Extended-release tablets: Initial: 2 mg orally once daily for 1 to 2 weeks, followed by increases of 2 mg/day at 1-week or longer intervals, depending on therapeutic response and tolerability Maximum dose: 24 mg orally once a day Patients may switch from immediate-release to extended-release: The initial dose of extended-release tablet should most closely match the total daily dose of immediate-release formulation. Following conversion, adjust dose depending on response and tolerability. Comments: -If significant interruption in therapy occurs, retitration may be necessary; upon discontinuation, this drug should be gradually tapered over a 7-day period. -The extended-release tablet is designed to release medication over a 24-hour period, if rapid gastrointestinal transit occurs, and tablet residue is observed in the stool, there is a risk of incomplete release of medication, Use: For the treatment of Parkinson's disease.

Usual Adult Dose for Restless Legs Syndrome:

Immediate-release tablets: Initial: 0.25 mg orally once a day on Day 1 and Day 2 Dose titration: May titrate as follows based on individual efficacy and tolerability: Days 3 to 7: give 0.5 mg orally once a day -Week 2: give 1 mg orally once a day -Week 3: give 1.5 mg orally once a day -Week 4: give 2 mg orally once a day -Week 5: give 2.5 mg orally once a day -Week 6: give 3 mg orally once a day -Week 7: give 4 mg orally once a day Maximum Dose: 4 mg orally once a day Comments: -Take 1 to 3 hours before bedtime. -In clinical trials, this drug was not tapered prior to discontinuation. Use: For the treatment of moderate to severe Restless Legs Syndrome.

Detailed Requip dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Requip XL if you are allergic to it.

To make sure Requip XL is safe for you, tell your doctor if you have:

high or low blood pressure; kidney disease (or if you are on dialysis); heart disease, heart rhythm problems; a sleep disorder such as narcolepsy, or other conditions that may cause daytime sleepiness; or if you smoke.

People with Parkinson's disease may have a higher risk of skin cancer (melanoma). Talk to your doctor about this risk and what skin symptoms to watch for.

It is not known whether Requip XL will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether ropinirole passes into breast milk or if it could affect the nursing baby. Ropinirole may slow breast milk production. Tell your doctor if you are breast-feeding.

Requip XL is not approved for use by anyone younger than 18 years old.

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Flashlamp-excited dye laser therapy of idiopathic vulvodynia is safe and efficacious. A modified posterior exenteration was performed in five patients. In the present study, we examined the short- and long-term effects of CT on the functionally excitatory 5-HT4 receptor-mediated decrease in the amplitude of the slow afterhyperpolarization (sAHP) that follows a calcium spike and the concomitant decrease in sAHP half decay time. Hippocampal alterations in children with temporal lobe epilepsy with or without a history of febrile convulsions: evaluations with MR volumetry and proton MR spectroscopy. Long-term infusion of benzodiazepines and opioids is strongly associated with dependence and withdrawal syndromes. Hereditary cerebello-lental degeneration with mental retardation. Age, duration of the disease, primary localization and previous operation were not prognostic factors. Although stage of disease and gestational age will largely influence the timing of the interventions, treatment of invasive cervical cancer is similar to the non-pregnant state.

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Fundamental mechanisms of enzyme action and their importance to the medical technologist. The change blindness paradigm included different attentional cueing (valid, invalid, no cue) conditions. This review discusses current knowledge of the structure, function, and regulation of the V-ATPase in S. On the other hand, the incorporation of GalCer, which is a precursor of SM4, had no effect on adherence of the cells to laminin or to fibronectin. It was also observed that tumor growth progressively becomes autonomous, through successive degradation of the multiple steps involved in the control of cell proliferation and differentiated activities.

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Postoperative pain has restricted the application of such which is stronger tretinoin gel or cream procedures in the day case setting. The taxonomy of the yeast genus Metschnikowia has undergone profound changes over the past century. Resulting values of model tissue have been interpolated and mapped into two-dimensional pattern in gray tone. The results of cure and survival from laparoscopic surgery of cancer of the rectum are being studied. Fifty-six Gluconobacter strains and one Acetobacter strain were isolated from honey bees and their environment in three different regions in Belgium and identified phenotypically. Both temporal bone findings and clinical features in partial trisomy 13 and partial trisomy 14 to some degree overlap with those of trisomy 13, partial trisomy 13 and partial trisomy 14.

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Angiogenesis is the process in which endothelial cells divide and migrate to form new capillaries, which support the continued growth of tumor through blood flow. Transfected cultures were exposed to five model mutagens and carcinogens: hydrogen peroxide (H(2)O(2)), 12-O-tetradecanoyl-phorbol-13-acetate (TPA), benzo-a-pyrene-diol-epoxide (BPDE), ethyl nitrosourea (ENU), 9-aminoacridine (9AA) and two controls: acetone and ethanol. However, immunohistochemical studies of frozen skin sections of biopsies of the two patients using monoclonal antibodies directed against three ppGalNac isoforms revealed the complete absence of immunostaining for ppGalNAc-T3 while the staining pattern for ppGalNAc-T2 and -T6 was identical in skin biopsies obtained from HFTC patients and healthy control individuals. The benefits to patient care of involving the general dental practitioner and the dental team in primary care services are emphasised. Elucidation of the specific molecular physiology of each of the genetic subtypes of long QT syndrome will not only allow precise diagnosis and, potentially, treatment of patients with the syndrome, but will enhance our understanding of the pathophysiology of arrhythmias in general, which will extend the benefit of more precise therapy to many patients in addition to those with the long QT syndrome. The solution is valid for finite strain of the cell membrane provided that the membrane is isotropic, elastic and incompressible. A fluid burr leaves cartilage with less injury and with a smoother surface than do more traditional surgical instruments.

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Porphyria in domestic animals: Danish observations in pigs and cattle and comparison with human porphyria. The aim of this study was to evaluate the efficacy of this new perineal sphincter constructed by transposing the gracilis muscles around an orthotopic colostomy in the attempt to avoid a permanent abdominal colostomy. Corrective osteotomies of the foot after compartment syndromes of the tibia. Arrival times of the labeled arterial blood bolus were measured in the carotid siphon (CS) and the middle cerebral artery (MCA) on both sides, and the corresponding side-to-side arrival time differences (ATDs) were calculated. Until now, the demonstration of cervical root pockets after root avulsion by means of the oily contrast medium Pantopaque has been considered to be the method of choice.

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Role of acyl coenzyme A cholesterol acyltransferase in intrahepatic processing of apo B-lipoprotein in suncus. The mutational mechanism consists in a misalignment between regions of almost identical sequence and the subsequent unequal recombination. Ambulatory esophageal manometry in the evaluation of unexplained chest pain. Antibody avidity of samples was measured by an inhibition EIA technique and urea denaturation test. Characterization of four variant forms of human propionyl-CoA carboxylase expressed in Escherichia coli. Understanding of feline dermatology will be furthered by including these syndromes in a broader grouping that encompasses all the feline eosinophilic dermatoses. Estimating rates of chronic fatigue syndrome from a community-based sample: a pilot study.

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