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Provera (Medroxyprogesterone)

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Provera is a progestin. It regulates menstrual periods by helping to balance the natural levels of the hormone progesterone. When taken together with estrogen-containing medications, it helps protect the uterus from the damage caused by estrogen.

Other names for this medication:
Curretab, Deviry, Empeea, Farlutal, Litmus, Medrigest, Medroxyprogesterone, Medtet, Megest, Megestone, Meprate, Orgamed, Parlutal, Premelle, Prodroxy, Regeeva, Remens, Sanigst, Topnid

Similar Products:
Duricef, Singulair, Colospa, Compazine, Seroquel, Exelon, Nimotop, Indocin, Dramamine

Also known as: Medroxyprogesterone


Medroxyprogesterone injection is used to prevent pregnancy. It is a birth control method that works by stopping a woman's egg from fully developing each month. The egg can no longer accept a sperm and fertilization is prevented.

No contraceptive method is 100 percent effective. Birth control methods such as having surgery to become sterile or not having sex are more effective than birth control pills. Discuss your options for birth control with your doctor.

This medicine does not prevent AIDS or other sexually transmitted diseases. It will not help as emergency contraception, such as after unprotected sexual contact.

Medroxyprogesterone injection is also used with other medicines to help relieve symptoms of inoperable, recurrent, and metastatic (cancer that has already spread) endometrial or kidney cancer.

This medicine is to be given only by or under the immediate supervision of your doctor.


Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Provera is usually given for only a few days in a row each month.

Have regular physical exams and self-examine your breasts for lumps on a monthly basis while using Provera.

If you need major surgery or will be on long-term bed rest, you may need to stop using Provera for a short time. Any doctor or surgeon who treats you should know that you are using Provera.

This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using Provera.

Store at room temperature away from moisture and heat.

Detailed Provera dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Provera dosage information

Side effects

The most common side effects associated with Provera are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You may need to have a negative pregnancy test before you start Depo-Provera Contraceptive.

You should not use Depo-Provera Contraceptive if you are pregnant, or if you have:

abnormal vaginal bleeding that has not been checked by a doctor; liver disease; breast cancer; or a history of stroke or blood clot.

Depo-Provera Contraceptive can decrease the calcium stored in your bones, which may cause bone loss (osteoporosis) when the medicine is used over long periods of time. Bone loss may not be reversible.

You may be more likely to have a broken bone if your bones get weak from calcium loss, especially after menopause. You should not use this medicine for longer than 2 years unless other birth control methods are not right for you. Ask your doctor.

Tell your doctor if you have ever had:

light or irregular menstrual periods; risk factors for osteoporosis (such as low bone mineral density, a family history of osteoporosis, drinking large amounts of alcohol, or if you smoke); a breast lump, an abnormal mammogram, or bleeding from your nipples; kidney disease; high blood pressure; breast cancer (in you or a family member); diabetes; depression, or an eating disorder; seizures; asthma; or migraine headaches.

Tell your doctor right away if you become pregnant, or if you plan to become pregnant soon after you stop using Depo-Provera Contraceptive.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

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