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Phenergan (Promethazine)

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Phenergan is an inexpensive drug used to treat allergic reactions and to treat or prevent nausea and vomiting from illness. It is also used to help treat pain or nausea after surgery.

Other names for this medication:
Abrozin, Admol, Avomine, Biodol, Brumol, Ceedokid, Citazine, Cofcodyl, Crophen, Ethamol, Febrinil, Fevril, Hyperex, Kelvin, Kosgan, Lagesic, Lincotuss, Metacet, Nimkair, Paracee, Paral, Paramax, Parapro, Phenomet, Pinex, Pizol, Primozyn, Progene, Promacot, Promegan, Promethazine, Promethegan, Promit, Promyoz, Propar, Prophen, Prosed, Prosip, Prosym, Prozine, Pyrex, Pyrhist, Symol, Tussdex, Tymol, Vomica, Vomin, Zinmol

Similar Products:
Ambien, Neoral, Wellbutrin, Tricor, Adalat

Also known as: Promethazine


Cough/cold combinations are used mainly to relieve the cough due to colds, influenza, or hay fever. They are not to be used for the chronic cough that occurs with smoking, asthma, or emphysema or when there is an unusually large amount of mucus or phlegm (pronounced flem) with the cough.

Cough/cold combination products contain more than one ingredient. For example, some products may contain an antihistamine, a decongestant, and an analgesic, in addition to a medicine for coughing. If you are treating yourself, it is important to select a product that is best for your symptoms. Also, in general, it is best to buy a product that includes only those medicines you really need. If you have questions about which product to buy, check with your pharmacist.

Since different products contain ingredients that will have different precautions and side effects, it is important that you know the ingredients of the medicine you are taking. The different kinds of ingredients that may be found in cough/cold combinations include:

Antihistamines—Antihistamines are used to relieve or prevent the symptoms of hay fever and other types of allergy. They also help relieve some symptoms of the common cold, such as sneezing and runny nose. They work by preventing the effects of a substance called histamine, which is produced by the body. Some examples of antihistamines contained in these combinations are:

Bromodiphenhydramine Brompheniramine Carbinoxamine Chlorpheniramine Dexchlorpheniramine Diphenhydramine Doxylamine Phenindamine Pheniramine Phenyltoloxamine Pyrilamine Promethazine Triprolidine

Decongestants—Decongestants produce a narrowing of blood vessels. This leads to clearing of nasal congestion. However, this effect may also increase blood pressure in patients who have high blood pressure. These include:

Ephedrine Phenylephrine Pseudoephedrine

Antitussives—Antitussives help relieve coughing and are some contain a narcotic. These antitussives act directly on the cough center in the brain. Narcotics may become habit-forming, causing mental or physical dependence, if used for a long time. Physical dependence may lead to withdrawal side effects when you stop taking the medicine.

Narcotic antitussives Codeine Dihydrocodeine Hydrocodone Hydromorphone

Non-narcotic antitussives Carbetapentane Caramiphen Dextromethorphan

Expectorants—Expectorants work by loosening the mucus or phlegm in the lungs. The main expectorant used in cough and cold medicines is guaifenesin. Other ingredients added as expectorants (for example, ammonium chloride, calcium iodide, iodinated glycerol, ipecac, potassium guaiacolsulfonate, potassium iodide, and sodium citrate) have not been proven to be effective. In general, the best thing you can do to loosen mucus or phlegm is to drink plenty of water.

Analgesics—Analgesics are used in these combination medicines to help relieve the aches and pain that may occur with the common cold. These include:

Acetaminophen Aspirin Other salicylates such as salicylamide and sodium salicylate

The use of too much acetaminophen and salicylates at the same time may cause kidney damage or cancer of the kidney or urinary bladder. This may occur if large amounts of both medicines are taken together for a long time. However, taking the recommended amounts of combination medicines that contain both acetaminophen and a salicylate for short periods of time has not been shown to cause these unwanted effects.

Anticholinergics—Anticholinergics, such as homatropine may help produce a drying effect in the nose and chest.

These cough and cold combinations are available both over-the-counter (OTC) and with your doctor's prescription.

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .


Take Phenergan exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Phenergan is often taken at bedtime or before meals. For motion sickness, Phenergan is usually started within 1 hour before traveling. When used for surgery, Phenergan is usually taken the night before the surgery.

How often you take Phenergan and the timing of your dose will depend on the condition being treated.

Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

If a child is using this medicine, tell your doctor if the child has any changes in weight. Phenergan doses are based on weight in children, and any changes may affect your child's dose.

Call your doctor if your symptoms do not improve, or if they get worse while using Phenergan.

This medicine can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using Phenergan.

Store Phenergan at room temperature away from moisture, heat, and light.

Detailed Phenergan dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include overactive reflexes, loss of coordination, severe drowsiness or weakness, fainting, dilated pupils, weak or shallow breathing, or seizure (convulsions).


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Do not keep outdated medicine or medicine no longer needed.

Keep out of the reach of children.

Detailed Phenergan dosage information

Side effects

The most common side effects associated with Phenergan are:

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Diagnosis and treatment of acute abdominal conditions with special reference to roentgenographic findings. Compared with previous studies in this population, we can estimate a modest and non-significant reduction of regular smoking, and a reduction in daily and regular alcohol use. Metabonomic strategy for the investigation of the mode of action of the phytotoxin (5S,8R,13S,16R)-(-)-pyrenophorol using 1H nuclear magnetic resonance fingerprinting. mRNA levels varied from case to case, but they were lower than those observed in MCLs. The action of laser and light-emitting diode radiation in the visible region on the content of reactive nitrogen species and activity of superoxide dismutase in rat wound fluid was studied, and efficiency of action of coherent laser and incoherent light emitting diode radiations in the red region of the spectrum on the parameters under study was compared. Accuracy of intraoperative staging of the NO neck in squamous cell carcinoma.

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Marsupialization of fistulotomy and fistulectomy wounds improves healing and decreases bleeding: a randomized controlled trial. This scFv 6009F was able to neutralize 2 LD(50) of Cn2 toxin when a 1 : 10 molar ratio of toxin-to-antibody fragment was used. Information processing during physical exercise: a chronometric and electromyographic study. The aim of this article is to present a new and challenging model of treatment that combines two therapeutic interventions: hydrotherapy and Snoezelen or controlled multisensory stimulation. It is clear that the risk of toxicity to normal tissues in combined therapy is reduced by separating drug administration and radiation exposure in time. Examination of the excised material by light and electron microscopy, and immunohistochemistry, revealed cells with features compatible with fibrocytes that did not stain positive for cytokeratin.

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Both B-cell epitopes and T-cell epitopes remain antigenic and immunogenic in the PhoE-associated conformation. Activated gelatinase-B (MMP-9) and urokinase-type plasminogen activator in synovial fluids of patients with arthritis. Strikingly, this mechanism leads to quantitative disassembly of the 19S into subcomplexes and free Rpn10, the polyubiquitin binding subunit. The MTRF is thus effective when target cells have been exposed to five genotoxic agents that act by different mechanisms. We show that even the most complete set of data do not allow to determine the absolute contributions of monomeric units, while their relative contributions may be determined. Retrospective cases involving 801 patients admitted to hospitals in Beijing between March and June 2003, with a diagnosis of probable SARS, moderate type. Pathological alterations of capillaries, accelerated epidermopoesis, increased rate and extent of metabolism in the psoriatic lesion and first manifestation of psoriasis rarely in the first 20 years of life made us decide to investigate the human growth hormone (STH) in blood serum.

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Contribution of the pudendal nerve to sensation of the distal rectum. Selection, evaluation, and control of the assay of the pharmaceutical product. Molecular characterization of 12q14-15 rearrangements in three pulmonary chondroid hamartomas. The complex is built up of at least two subunits of M(r) 20,000 and 22,000, which are encoded in the nucleus as precursor proteins of M(r) 27,000. While the answer appears to be obvious, we had to overcome two challenges. A 72-year-old man presented with a 6-month history of dysphagia, fatigue, 60-lb weight loss, and central nervous system (CNS) deficits. gingivalis that are recognised by sera from patients with periodontitis. A 5 MHz phase arrayed 12 mm ultrasound probe was used as guidance system. Oxidation of 1-14C-ascorbic acid in the guinea pig: effect of the route of administration.

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The results suggest a need for an in vivo study of serum drug levels after RYGB surgery in patients taking psychiatric medications. Genotyping for this marker in 234 F2 progeny of a SHR x BN intercross mapped the gene to rat chromosome 13. Pneumonia due to respiratory syncytial virus diagnosed myambutol 400 mg tablet by transtracheal aspiration in an adult. By comparing results from this technique with results from a conventional electrophoresis technique (FDR assay) that detects all rejoining events, it was possible to quantitate the misrejoining frequency after 50Gy of X irradiation. Assessment of high doses of bacterial antigen-antibody in various eye, ear, nose and throat diseases. Iron- and sulfur-oxidizing autotrophic bacteria were present wherever mine water entered a stream system.

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The aggregation para que es el enalapril maleato 20 mg number has been determined at different temperatures. Cystic hydatic disease in sheep: treatment with percutaneous aspiration and injection with dipeptide methyl ester. The exact mechanism of the interaction is unknown but it has been suggested that there is a direct effect on plasma heparin characterised by a reduction in circulating plasma heparin levels. rhGH appears to be capable of directly altering the adhesive and migratory capacity of human T cells to molecules of either murine or human origin. The effects of nicotine on glutamate-induced cytotoxicity were examined using primary cultures of rat cortical neurons. Among postmenopausal women with coronary artery disease, the 2003 definition for impaired fasting glucose was not associated with increased risk for new CHD, stroke or TIA, or CHF. A field study of 182 university students in their residences tested the relationships among subjective time pressure, Type A scores, and organizational citizenship behavior.

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Three exposure times (20, 10, and 5 minutes) and four exposure concentrations (2, 1, 0.8, and 0.5 ppm) were used to define 12 inhalation exposure scenarios for BD. Occurrence of de novo ABL kinase domain mutations in primary bone marrow cells after BCR-ABL gene transfer and Imatinib mesylate selection. Synthetical and real data are used to demonstrate the obstructions caused by this effect and the quality improvement of the reconstructions. The patient had bilateral optic disc dysplasia in association with a basal encephalocele, but had no midline facial anomalies. An institutional review board-approved retrospective database and record review from 1994 through 2004 at a quaternary referral center for vascular anomalies was conducted.

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Recent progress of structural biology of tRNA processing and modification. The 98-day study was divided into one 2-week preperiod and two 6-week experimental periods in a cross-over design. Protein L-isoaspartyl methyltransferase: developmentally regulated gene expression and protein localization in the central nervous system of aged rat. The stereoselectivity for the formation of 1,2-trans-glycosidic bonds was the highest with the p-methoxy-benzylidene derivative with triphenylmethylium triflate as the promoter. Mesenteric lymphadenitis due to Pasteurella pseudotuberculosis with symptoms simulating acute appendicitis. Metabolites that accumulate in blood of the affected organism diffuse into the transport medium and, from there, into blood of the healthy organism, which metabolizes them. It was shown by gel filtration that ribonucleases U(1), U(2) and U(3) have molecular weights about 10000 like ribonuclease T(1), and that ribonuclease U(4) is much larger. Determination of the enzymes of glycolysis and of the citric acid cycle in synovial fluid.

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In several countries, including the US, active management of MND is practised using ventilatory support to manage respiratory insufficiency. The importance of individual calculation of the digoxin dosing regimen in patients with renal failure is reemphasized. Both indirect and direct evidence is presented in support of the Prescribed Evolutionary Hypothesis. Cells expressing EPOR-ME exhibited increased Epo sensitivity compared to cells expressing wild type EPOR. Fifty eight Spanish BD patients and 116 ethnically matched unrelated healthy subjects were typed at the HLA-DRB1 and HLA-DQB1 loci using polymerase chain reaction/sequence specific oligotyping (PCR/SSO).

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Echocardiographic, electrophysiologic, Holter monitoring, cardiac catheterization, and endomyocardial biopsy results were analyzed. SkinTemp dressing appears to be less painful and has a better healing rate compared with Xeroform. Dynamics of hip joint effusion after posterior soft tissue repair in total hip arthroplasty. There was a significantly higher incidence for boys (18.8/100 000/year) than for girls (16.4/100 000/year). The cDNAs of AdR and Adx on the first plasmid were separated by a ribosome binding sequence, with the reductase preceding the ferredoxin. Prognosis is very grave, and median survival time is only several weeks. The lysozyme gene is expressed at a low level in myeloblasts and is progressively activated to constitutively high expression in mature macrophages. Further investigations demonstrated that human pulmonary fibroblast cells cultured on line and point micropatterns showed inflammatory response. Both laparoscopic Nissen fundoplication (LNF) and proton-pump inhibitor (PPI) therapy are established in the treatment of gastro-oesophageal reflux disease (GORD). In considerable attendant disorders of pulmonary hemodynamics the dose of biaxin antibiotic uses hypothiazide should be proportionally increased, while the dose of obsidan is reduced.

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Mouse peritoneal macrophages cultured in the presence of IFN-gamma alone or IFN-gamma plus LPS rapidly depleted the medium of L-arginine, a substrate for iNOS, and stopped producing NO. We analyzed the effectiveness of quinacrine as an inhibitor of MMP activation in leukocytes and investigated the mode of action. Bartonella quintana was isolated from 34 BACTEC nonradiometric aerobic resin blood cultures for 10 adults. Although a parasitic association cannot be excluded, no evidence was obtained of the midge biting activity, neither by direct observation nor indirectly, by detecting the expected lesions on the host cuticle. Modulation of expression risperdal anxiety medicine of superantigens by human transferrin and lactoferrin: a novel mechanism in host-Streptococcus interactions.

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Long-term highly active antiretroviral therapy in chronic HIV-1 infection: evidence for reconstitution of antiviral immunity. Expression of major histocompatibility antigens and vascular adhesion molecules on human cardiac allografts preserved in University of Wisconsin solution. The observed difference in virulence toward apterous and winged aphids may have an ecological impact, and this deserves specific attention in future research. Sarafotoxins and endothelins: evolution, structure and function. The dose-response effect of gliclazide and glibenclamide on ischaemic preconditioning and the action of glibenclamide on signal transduction in human myocardium were investigated using right atrial appendages from cardiac surgery patients. Conformationally, I and II appear identical and both can i drink alcohol when taking zithromax manifest several unusual resonance shifts suggestive of a glycopeptide secondary structure involving four specific hydrogen bonds. Liver function (liver function and serologic parameters for liver fibrosis) was observed at wk 0, 6, 12, 18 and 24. The function of a hydrogen peroxide-detecting electroenzymatic glucose electrode is markedly impaired in human sub-cutaneous tissue and plasma.

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