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Penamox (Amoxicillin)
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Penamox

Penamox is a penicillin-like (beta-lactam) antibiotic. It belongs to the most widely-used group of antibiotics available. Penamox is usually the drug of choice within the class because it is better absorbed, following oral administration, than other beta-lactam antibiotics.

Other names for this medication:
Alfamox, Almodan, Aloxyn, Amoclen, Amoksicilin, Amopen, Amoram, Amoxi, Amoxicilina, Amoxicillin, Amoxicillinum, Amoxiline, Amoxisol, Amoxivet, Amoxypen, Amurol, Bimoxan, Bristamox, Cipmox, Flemoxin, Flemoxon, Gimalxina, Hidramox, Hydramox, Moxicillin, Novamoxin, Ospamox, Penamox, Penimox, Polymox, Raylina, Reloxyl, Robamox, Servamox, Solciclina, Stacillin, Sumox, Tolodina, Utimox, Velamox, Wymox

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Also known as: Amoxicillin

Description

Amoxil (amoxicillin) is a penicillin antibiotic that fights bacteria.

Amoxil is used to treat many different types of infection caused by bacteria, such as tonsillitis, bronchitis, pneumonia, and infections of the ear, nose, throat, skin, or urinary tract.

Amoxil is also sometimes used together with another antibiotic called clarithromycin (Biaxin) to treat stomach ulcers caused by Helicobacter pylori infection. This combination is sometimes used with a stomach acid reducer called lansoprazole (Prevacid).

Dosage

Adults: 500 mg PO every 12 hours or 250 mg PO every 8 hours for mild/moderate infections and 875 mg PO every 12 hours or 500 mg PO every 8 hours for severe infections.

Infants older than 3 months, Children, and Adolescents: 20 mg/kg/day PO in divided doses every 8 hours (Max: 250 mg/dose) or 25 mg/kg/day PO in divided doses every 12 hours (Max: 500 mg/dose) for mild to moderate infections and 40 mg/kg/day PO in divided doses every 8 hours (Max: 500 mg/dose) or 45 mg/kg/day PO in divided doses every 12 hours (Max: 875 mg/dose) for severe infections.

Neonates and Infants 3 months and younger: 30 mg/kg/day PO given in divided doses every 12 hours.

Overdose

In case of overdosage, discontinue medication, treat symptomatically, and institute supportive measures as required. If the overdosage is very recent and there is no contraindication, an attempt at emesis or other means of removal of drug from the stomach may be performed. A prospective study of 51 pediatric patients at a poison-control center suggested that overdosages of less than 250 mg/kg of Penamox are not associated with significant clinical symptoms and do not require gastric emptying.

Interstitial nephritis resulting in oliguric renal failure has been reported in a small number of patients after overdosage with Penamox.

Crystalluria, in some cases leading to renal failure, has also been reported after Penamox overdosage in adult and pediatric patients. In case of overdosage, adequate fluid intake and diuresis should be maintained to reduce the risk of Penamox crystalluria.

Renal impairment appears to be reversible with cessation of drug administration. High blood levels may occur more readily in patients with impaired renal function because of decreased renal clearance of Penamox. Penamox may be removed from circulation by hemodialysis.

Storage

Store between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Keep bottle closed tightly. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Penamox are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Crossreactivity of IgE antibody against Dermatophagoides farinae (Der f) with Limulus polyphemus agglutinin (LPA) was examined using RAST and immunoblot analysis. Upon binding of fasciculin, subtle structural rearrangements of AChE occur that could explain the observed residual catalytic activity of the fasciculin-enzyme complex. The translated amino acid sequence consists of 601 amino acids (65.8 kDa) with a single putative membrane-spanning region and a N-terminal cytoplasmic domain of 106 amino acids. To determine the tolerability and pharmacokinetics of oral CI-1033, a pan-erbB tyrosine kinase inhibitor, administered over 14 consecutive days of a 21-day cycle. The changes of oxidant and anti-oxidant system of alveolar macrophage under the influence of quartz were studied from different angles such as in vitro cell test, experimental rat silicosis and patients with silicosis. Acute hypotension in the setting of hemorrhage most often signifies abrupt and dangerous blood loss. Frozen sections of liver tissue were stained according to alkaline phosphatase anti-alkaline phosphatase method. A low level of inducible NO synthase mRNA was detectable in tumors by Northern blotting, with a weak increase during tumor growth.

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