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Octrim (Trimethoprim)

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This medication is a combination of two antibiotics: sulfamethoxazole and trimethoprim. It is used to treat a wide variety of bacterial infections (such as middle ear, urine, respiratory, and intestinal infections). It is also used to prevent and treat a certain type of pneumonia (pneumocystis-type). This medication treats only certain types of infections. It will not work for viral infections (such as flu). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.

Other names for this medication:
Alfatrim, Bactelan, Bacticel, Bactipront, Bactiver, Baktimol, Betam, Chemitrim, Cotrimox, Cotripharm, Diseptyl, Dosulfin, Editrim, Esbesul, Eusaprim, Gantrisin, Gentrim, Irgagen, Kanprim, Methotrin, Metoxiprim, Neoset, Novidrine, Onetrim, Primazole, Purbac, Qiftrim, Regtin, Septrin, Sinatrim, Sulbron, Sulfamethoxazole, Sulfametoxazol, Sultrian, Trimetoger, Trimexazol, Trimoxsul, Tripur, Trisulin, Trizole, Urisept, Vanadyl, Wiatrim, Zoltrim

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Also known as: Trimethoprim


Generic Octrim is taken to fight against ear infections, urinary tract infections, bronchitis, traveler's diarrhea, Pneumocystis carinii pneumonia. Generic Octrim works by killing or slowing the growth of sensitive bacteria. Generic Octrim can't be given to children younger than 2 months old. Octrim is also known as Co-trimoxazole, Septra, Ciplin, Septrin. Generic names of Generic Octrim are Sulfamethoxazole, Trimethoprim. Brand names of Generic Octrim are Octrim, Octrim DS, Septra, Septra DS, Sulfatrim Pediatric.


Adults: The usual adult dosage in the treatment of urinary tract infections is 1 Octrim DS (double strength) tablet or 2 Octrim tablets every 12 hours for 10 to 14 days. An identical daily dosage is used for 5 days in the treatment of shigellosis.

Children: The recommended dose for children with urinary tract infections or acute otitis media is 40 mg/kg sulfamethoxazole and 8 mg/kg trimethoprim per 24 hours, given in two divided doses every 12 hours for 10 days. An identical daily dosage is used for 5 days in the treatment of shigellosis.


If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe nausea/vomiting/diarrhea, severe dizziness or drowsiness, mental/mood changes.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Bactrim DS dosage information

Side effects

The most common side effects associated with Octrim are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Octrim is contraindicated in patients with a known hypersensitivity to trimethoprim or sulfonamides, in patients with a history of drug-induced immune thrombocytopenia with use of trimethoprim and/or sulfonamides, and in patients with documented megaloblastic anemia due to folate deficiency.

Octrim is contraindicated in pediatric patients less than 2 months of age. Octrim is also contraindicated in patients with marked hepatic damage or with severe renal insufficiency when renal function status cannot be monitored.

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The condylar movements during jaw opening were introduced as the loading condition in the analysis. In situ screening assay for cell viability using a dimeric cyanine nucleic acid stain. The biochemical changes leading to this reduction are summarized, and a suggestion is made regarding the optimal dosage of progestogen. Progression of insufficiency and operative results in young children. In contrast, morphine (1-5 mg kg-1, s.c.) inhibited both phases of formalin-induced pain with an ID50 of 2.5 mg kg-1. Symptoms of TM were abolished in 26 of the 28 patients after aortopexy. The response of human retinal cells to growth factors and hormones is similar to the response of rodent retinal cells to the same factors, suggesting that the effects of these factors are conserved across species. Thalidomide therapy reduced not only serum TNF alpha levels and the clinical symptoms but also the dermal infiltration of polymorphonuclear leukocytes and T cells. Titanium and alumina prostheses for the hip, femur, tibia, shoulder and humerus have been designed by the senior author. Impact of previously unrecognized benign prostatic hyperplasia on the daily activities of middle-aged and elderly men.

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The dacryocystorhinostomy remains the first choice operation for obstructions below the lacrimal sac. Also, a repeated dosage of diazepam (3 x 5 mg/kg/day SC on postnatal days 5 to 7) induced a significant depression of humoral immune response in 7-month-old rats. A comparison of the teratogenic activity of thalidomide in rabbits and rats. This study comprised all complaints submitted from 1980 to 1990 by coronary patients and their relatives to the Finnish National Board of Health (NBH). The Stat91 pathway regulated c-fos gene transcription involves activation by tyrosine phosphorylation of the DNA binding factor SIF (sis-inducing factor) in the cytoplasm, its nuclear translocation, and interaction with the regulatory element SIE (sis-inducing element). Hemagglutination titers of La Crosse virus antigens prepared in BHK-21 suspension cell cultures were substantially increased by precipitating the antigens with polyethylene glycol. Short-term improvement in submaximal exercise capacity by optimized therapy with ACE inhibitors and beta blockers in heart failure patients is associated with restoration of peripheral endothelial function. The average duration of mechanical supportive care was 99 hours. Direct-to-consumer advertising: should there be a free market in healthcare information?. Intermediate segment outgrowth (ISOs) are transitory specialisations of the plasma membrane of intermediate segments of the posterior median photoreceptors of Dinopis.

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All of these studies have shown a beneficial effect in preserving renal function. Most of them demonstrated their correct understandings about menopause issue and daily life in menopause and half of them demonstrated their correct understandings about HRT. However, it is disturbing that most in vitro studies have failed to prove that hCG is truly capable of stimulating the human thyroid. Histological examination of duodenal biopsy specimens revealed a decreased number of intraepithelial lymphocytes. This review considers the current literature on the prevalence, presentation, treatment and assessment of depression in autism and Asperger syndrome. Therefore subjects aged above 60 years are recommended to be included into active immunizations against tetanus. Both biomaterials caused a foreign body reaction, persisting up to 12 wk after surgery. Datasets obtained in this way are subjected to simultaneous pharmacokinetic/pharmacodynamic modelling to obtain estimates of pharmacodynamic parameters such as EC50, Emax, Hill factor and the rate of biophase equilibration. The effects of age and the Charlson comorbidity index on the baseline probability of adverse outcomes following total knee replacement were shown to be similar to or greater than the effect of hospital volume.

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Immunostaining was present, but less intense, in normal arteries of comparable size. Chronological changes in subjective symptoms during pregnancy in nulliparous and multiparous women. Safety and efficacy study of delapril versus enalapril in patients with congestive heart failure. Chromosome rearrangements involving band 19p13 have been described in about half of all ovarian carcinomas. Two pathways leaving the rostral part of the Edinger-Westphal nucleus were studied, a peripheral and a central descending pathway. Only sponges with small pores (less than 50 micrometer) were able to withstand weight-bearing. Km for aspartate as well as Kd for the binding of the bisubstrate analog N-(phosphonacetyl)-L-aspartate are significantly higher than the analogous values for wild-type ATCase. These cells may be useful for potentiation of wound healing because they retain their pluripotential differentiation ability.

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Results showed the average effective dose for spiral CT to be less than conventional CT, and the dose in the body surface was generally lower than the dose in the central region. Shotgun proteomics has emerged as a powerful approach for the analysis of complex protein mixtures, including biofluids, tissues, cells, organelles or protein complexes. Fine specificity of peptide determinants for indirect T cell recognition of class I MHC alloantigens. Regulation of ribonucleotide reductase M2 expression by the upstream AUGs. From April 2000 through April 2001, 33 internal medicine residents completed pretest-posttest questionnaires evaluating changes in their knowledge, attitudes and intention to care for HIV-infected patients.

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In this study, we synthesized several isostructural analogs of estrone sulfate (estrone-3-methylsulfonate, estrone phosphate, 3-desoxyestradiol-3-methylenesulfonate, and 3-desoxyestrone-3-methylenesulfonate) and tested them on human placental sterylsulfatase. We have used acylated analogs of gramicidin as a model to study the interaction between a covalently coupled fatty acid and the hydrophobic part of a membrane-spanning protein in a bilayer environment. Inhibition of cultivable bacteria by chlorhexidine treatment of dentin lesions treated with the ART technique. Characterization of two classes of ribonucleoprotein complexes possibly involved in RNA editing from Leishmania tarentolae mitochondria. This suggests that there are no significant differences in the metabolism of galactocerebroside in the myelin and myelin-forming cells in individual nerve fiber tracts throughout the murine brain. Effect of methanol on endogenous and exogenous carnitine levels in rat plasma. In contrast, down-regulation of caveolin 1 with antisense oligonucleotide significantly inhibited the features of chondrocyte senescence induced by catabolic factors. Metabolic coupling is investigated with a recent mathematical model incorporating glycolytic oscillations.

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This study was to evaluate the feasibility of inducing immunotherapy on pancreatic cancer by K-ras mutated peptides, give experimental evidence to clinical individual therapy on pancreatic cancer. Platelet activation markers: sP-selectin, platelet factor 4 (PF4), beta-thromboglobulin (betaTG) and monocyte chemotactic peptide-1 (MCP-1) were measured and compared in different stages of LC. Molecular basis of cross-reactivity among allergen-specific human T cells: T-cell receptor V alpha gene usage and epitope structure. Histochemically, cytochrome c oxidase activity decreased, especially at the anterior lobe in the cerebellar cortex of the heterozygote. To localize cells in axotomized ganglia which increase their expression of these mRNAs, we performed in situ hybridization studies. Androgens were not able to induce the epithelial prometrium capsules inserted vaginally differentiation in vitro before the first signs of mesenchymal differentiation were evident in vivo.

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No difference in survival was found according to occupation, size of town of residence, place of birth, or type of hospital. Docetaxel is subject to extensive metabolic conversion by the cytochrome P450 (CYP) 3A isoenzymes, which results in several pharmacologically inactive oxidation products. Increased levels of fibrin monomer, increased fibrin/fibrinogen degradation products, and absent or low levels of fibrinogen in the ascites of all patients tested confirmed the presence of intraperitoneal coagulation when ascites is present. Eleven patients were studied before and 3 months after a floppy Nissen fundoplication. Results on multipatient 3-D MRI registration illustrate the ability of the method to preserve topology on the continuous image domain. Somatosensory evoked potentials elicited by mechanical and electrical stimulation of each single pain can you buy celebrex over the counter in australia or tactile spot of the skin. The function of IL-18R was confirmed by induction of IL-8 release from epithelial cells in response to recombinant IL-18. Bile duct involvement in hepatocellular carcinoma: MR demonstration. The testing of the carcinogenic potential of different chemical substances and radiations. Alcian blue--positive areas were dominant over MUC-1 core protein--expressing areas in well-differentiated cholangiocarcinoma, whereas the reverse was the case in poorly differentiated cholangiocarcinomas and also in cholangiocarcinoma areas of hepatocellular-cholangiocellular carcinoma.

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SGCaller: a program to call and review genotypes measured by sequencing. HIV counselling and testing of pregnant women attending antenatal clinics in Botswana, 2001. Probing perturbation of bovine lung surfactant extracts by albumin using DSC and 2H-NMR. Bronchiolitis obliterans, defined histologically or clinically, is the most significant long-term cause of morbidity and mortality after lung transplantation. Comprehensive treatment, including bone marrow transplantation (BMT) and biotin, resulted in immunological recovery, but no improvement of neurological condition. Whether CTX affects exercise-induced changes in cardiac deformation and mitral regurgitation (MR) in patients with end-stage heart failure has not been studied. SGS1 encodes a DNA helicase whose homologues in human cells include the BLM, WRN, and RECQ4 genes, mutations in which lead to cancer-predisposition syndromes.

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The experimental transmission of myxomatosis in brush rabbits (Sylvilagus bachmani theolair 250 mg ) by several species of mosquitoes. VEGF develops a cell-protective influence on endothelial cells exposed to simulated microgravity. Scaphoid nonunion: treatment by open reduction, bone graft, and staple fixation. This was a prospective, hospital-based study, undertaken on liveborn infants born over a 3-year period, 1 May 1986 to 30 April 1989. In 10-day-old rats, the oral epithelium over the mesial cusp gradually thickened, and nerve fibres with substance P- or CGRP-IR were found especially in its basal layer. PAPU reserve existed in all the patients, but those with rapidly progressive LN. The presence of carriers without neuromuscular symptomatology is of note, this fact reinforcing the need to incorporate DNA examination in the evaluation of asymptomatic relatives or with exclusive ocular symptomatology. We conclude that the smooth pursuit system and the cerebellum are critical for generating the eye movements required as subjects fixate a near target during translational head movements. Part of these SIV-neutralizing antibodies were directed specifically to the V2 region, as shown by neutralization-blocking experiments.

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Comparison of autogenous vein bypass grafts with patch angioplasty for short femoropopliteal occlusions. The adherence between the free end of the bovine penis and its sheath. Transapical left ventricular bypass which withdraws blood directly from the left ventricular apex through a roller pump and outflow filter with return to the femoral artery has been applied in 6 patients with cardiac failure. These results are in agreement with previous data obtained in adult rats and indicate that aging does not compromise the social memory improving and antidepressant-like activities of oxytocin. Fifty-five cerebrospinal fluid (CSF) specimens from 42 patients with suspected meningeal tumor involvement were reviewed. The double intubation technique is a good option in lower lacrimal system obstructions when conventional techniques have a high index of failure. MFH-1, a new member of the fork head domain family, is expressed in developing mesenchyme. The binding of p55 to a heterologous nuclear localization sequence of the SV40 large T suggests that it may also be involved in the transport of proteins other than the ER.

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Advances in treatment of gastric hypersecretion and the gastrinoma. Three of them were typical chordomas and 6 were chondroid chordomas. Only one other patient with an interstitial deletion of this band has been previously reported. Effect of Pasteurella bacterin on mortality and pneumonia in lambs. In the case of bone, extensive analysis of the pathogenetic mechanisms of systemic bone diseases may provide new important information on the factors in bone metabolism. Growth characteristics and Ha-ras mutations of cell cultures isolated from chemically induced mouse liver tumours. The site where transcranial magnetic stimulation excites the accessory nerve was studied in 5 cats. The dose-effect curves were linear-quadratic for all the parameters studied.

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The immunoperoxidase test was used to detect influenza virus in cells of a chorionallanthois shell of infected chicken embryos. This survey also revealed 192 epididymal tumours, essentially cysts, 8 squamous cell carcinomas of the penis and 3 adenocarcinomas of the female urethra. While only slight but significant differences could be detected of the average spontaneous, DEB- and bleomycin (G2)-induced chromosome breakage between patient and control lymphocytes, individual patients and two of the control individuals showed a more distinct increase in the frequency of the studied end points. Ontogeny of total body oxygen stores and aerobic dive potential in Steller sea lions (Eumetopias jubatus). The method was evaluated by comparing DNA yields using different DNA extraction procedures, after which the DNA was used for microbial community analysis by PCR-denaturing gradient gel electrophoresis (PCR-DGGE) of 16S ribosomal RNA (rRNA) and for quantification of 16S rRNA gene copy numbers in environmental samples by real-time PCR. Spasm scores and colonoscopy yield did not differ between glucagon and placebo in either study. Poly-drug abusers, who had undergone psychosocial treatment, had scores somewhat below normative scores.

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Because of potentially significant differences in skin permeation and metabolism between small animals and humans, we have used Yucatan microswine as an alternative model for testing topical retinoids. Reduction of blue tetrazolium in developing sea urchin eggs after addition of various substrates and phosphopyridine nucleotides. The suggested determination of the modified characteristic directions of the magnetic field due to anisotropy enhances the insight in the structural details of the system and analytical solutions of the secular equation for these conditions are derived. When subjected to TX-114 phase partitioning, a significant fraction of all of the proteins, including those with no palmitate, was found in the detergent-rich phase. Non-pharmacologic interventions to treat OAB can be effective but require patients to be highly motivated. Emerging pharmacological strategies in the fight against cocaine addiction.

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The contractile response of an isolated rabbit dilator muscle to a field stimulation was inhibited by pilocarpine. In order to monitor the efficacy of the drug and any side effects the patient should preferably be evaluated every three to six months. Short term memory and coding behavior as a function of set during sequential trials. The enzyme was active in vivo during arginine fermentation and at the onset of oxygen limitation in batch cultures. The results indicated that at short ISIs, variations in both talker and speaking rate imposed a processing cost that was reflected in poorer serial recall for the primary portion of word lists.

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Several recently developed techniques circumvent this problem, allowing accurate quantitation of RNA using RT-PCR. The article substantiates the influence of transthoracic microelecrostimulation on the healing of infarcted myocardium. A comparison of baccalaureate nursing programs in the United States and in Taiwan, R.O.C. This tumor inhibition was correlated to a marked reduction in tumor vascularization and mitotic activity. Transcriptional organization and regulation of the Vibrio anguillarum heme uptake gene cluster. MAP values and perfusion-CT results in these groups were compared using Kruskal-Wallis and Wilcoxon (Mann-Whitney) tests. Aspects of science in Scandinavian rheumatology--the making of a specialty. Epidemiologic studies indicate that paternal exposure to lead or mercury might be associated with the risk of spontaneous abortion. Standards and guidelines are useful elements in quality development and helpful to influence practice of health professionals. The compound was produced at a maximal level when cell cultures reached the onset what over the counter medicine is similar to protonix of stationary phase.

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The physiology of granulocytic cells in normal and leukemic states. Intensive chemotherapy with autologous peripheral blood stem cell transplantation during a 10-year period in 64 patients with germ cell tumor. The diagnosis was confirmed radiologically and with radioisotope examinations. There have been no previous reports of daily home activities of individuals with dementia being guided by the combination of music and verbal messages. Following separation of the preincubated samples by SDS-PAGE, a distinct pattern of degradation fragments was observed which was similar in all cases.

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