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Limited data suggest that fluticasone propionate also has considerable potential in the management of childhood asthma. Reviewed here are improvements in the treatment of four complex cardiac anomalies that occur in newborns and are associated with high mortality when left untreated. Normal specification of the extraembryonic lineage after somatic nuclear transfer. From 13C NMR, information on phi, psi and chi torsions can be obtained, permitting both assignment verification, and structure refinement and prediction. Despite significant increases in respiratory-related phasic alterations, there were no parallel increases in excitatory phenomena, i.e., eye movements or pontogeniculooccipital waves. No differences in the equilibrium constants were detected between patients and controls but a small increase in the albumin concentration was noted in the depressives. These findings indicate that Pti1 is involved in a Pto-mediated signaling pathway, probably by acting as a component downstream of Pto in a phosphorylation cascade.
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We have used a monoclonal antibody, A2, to study the structure and function on the lipid droplet capsule in steroidogenic adrenal cells. We evaluated Bio-Oss, which is a natural bone mineral derived from a bovine source that is chemically and physically identical to human bone, as a possible replacement material to reconstruct skull defects in a rabbit model. In both genotypes the dendrites of granule cells and the somata and dendrites of Golgi cells are synaptic targets of the glomeruli of the cortical projection. In this context, lysosomal proteases are essential not only for the generation of antigenic peptides but also for proteolysis of the invariant chain to allow the maturation of class II MHC molecules. Laparoscopic cystectomy: an experimental model of urinary diversion.
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Genetic and physical mapping of five novel microsatellite markers on human Xp21.1-p11.22. We used DNA fingerprinting by the arbitrarily primed polymerase chain reaction (AP-PCR) technique for an epidemiological investigation of 23 Pseudomonas cepacia isolates obtained from 11 cystic fibrosis (CF) patients attending our CF center. Diagnosis and medical treatment of pouchitis in ileal pouch-anal anastomosis in patients with ulcerative colitis. Repeated administration of dexamethasone to rats with an established hyperresponsiveness that was no longer associated with cellular inflammation had minimal effects on this hyperresponsiveness. A review of the late results indicated that the response of patients with this complication is similar to that of patients with other complications of ulcer disease treated in the same manner. We have used retrovirus-mediated gene transfer to express the terminal complement inhibitor protein, human CD59, in neonatal porcine aortic endothelial cells (nPAEC). Radioimmunoprecipitation demonstrated that the mutant envelope proteins were incorrectly processed. In addition, murine MoAbs (BALB/c) generated to native SV40 T-ag, and previously characterized as recognizing the carboxyl-terminus of SV40 T-ag by deletion mutant analysis, also bound the synthetic peptide (residues 690-708) defining the carboxyl-terminus of SV40 T-ag. 2-D Fourier analysis of electron micrographs of the lens cells quantified the dimensions of the spatial fluctuations in electron density of the lens cell microstructure.
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Eosinophils were shown to play a major role in the allergic inflammatory process leading to the clinical symptoms of atopic dermatitis. Treatment planning consists of addressing potential sources of failure of pain management, setting appropriate goals, and using the diagnostic assessment to plan pharmacologic and nonpharmacologic interventions based on pain mechanisms. A 76-year old man was referred for radiological evaluation of recurrent left sided flank pain, micro-haematuria and renal cysts. Comparative study of 6-chloropurine and 6-mercaptopurine in acute leukemia in adults. Albedo of the south pole on Mars determined by topographic forcing of atmosphere dynamics.
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Antisense technology has advanced substantially in the past few decades and now is a well-established therapeutic approach in medicinal chemistry, and it may prove to be a valuable tool in the treatment of a wide range of diseases. Our results indicate that FBP11 represents an ovule identity gene. For the first time, the adenylyl cyclase system (ACS) sensitive to biogenic amines in the mollusk Anodonta cygnea ganglions was revealed and characterized. Genomic and biochemical evidence suggests that three archaeal species (Methanocaldococcus jannaschii, Thermoplasma acidophilum and Thermoplasma volcanium) produce ribose-5-phosphate via the nonoxidative PPP (NOPPP), whereas nine species apparently lack an NOPPP but may employ a reverse RuMP pathway for pentose synthesis. Patterns of macromolecular synthesis in normal and virus-infected mammalian cells. The cells were columnar to cuboidal with eosinophilic cytoplasm, clear chromatin, nuclear grooves, and occasional nuclear pseudoinclusions. Laboratory simulated dissipation of metsulfuron methyl and chlorimuron ethyl in soils and their residual fate in rice, wheat and soybean at harvest. History and examination at this stage were not suggestive of an underlying serious disorder, but routine blood testing revealed abnormal results and prompted further investigations.
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Correlation between levels of N-terminal pro-B-type natriuretic peptide and degrees of heart failure. During the process of ischemia-reperfusion, the thioredoxin (Trx) system (consisting of thioredoxin reductase (TR), Trx and NADPH) prevents susceptible proteins from this oxidative modification. Expression of the Alcaligenes eutrophus phbA gene in Escherichia coli using a positive selection vector based on phage Lambda lysis genes. The cryptic mating type information that is copied and inserted at MAT is contained in either of two loci, HML or HMR. Since there is a 2 day lag period between the addition of T3 and the upregulation of keratin gene expression and terminal differentiation, recent studies have focused on identifying the genes activated during the lag period. Advantages over other approaches included no external scar, less damage to adjacent tissue, and wide exposure to the entire medial wall. Myelodysplastic syndrome associated with myelofibrosis, a report of 3 cases. Barbiturates, dissociative anesthetics, antidepressants, and neurosteroids have been shown to inhibit nicotinic receptors by allosteric mechanisms and/or by open- and closed-channel blockade. The most sensitive (.72) but the least specific (.86) test for RA was the latex test. Although there is no overall differential in adult cancer risk, these data support the hypothesis that the in utero environment may play an important role in specific cancers.
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The candidate tumor suppressor ING4 represses activation of the hypoxia inducible factor (HIF). The use of beta-methylthioethyl esters for the protection of carboxyl groups in peptide synthesis: removal through the beta-methylsulphonylethyl ester. with the glioma in 5 nude mice when compared to contralateral control tumors consisting of the U87 glioma and IL-4-negative control cells. Change in the definition of osteoporosis especially on bone quality. For people with disabilities, a physically active lifestyle can reduce the risk of secondary health problems and improve overall functioning. We have optimized a solid-phase extraction coupled with high-performance thin-layer chromatography (HPTLC) to provide rapid, simple, and sensitive detection of phenolphthalein, danthron, rhein, aloin, and bisacodyl and its metabolites in urine. Ischemic pain was examined in adult males with and without a parental history of hypertension. To discuss the utility of automatic ambulatory blood pressure recording in assessing antihypertensive therapy. Tryptophan hydroxylase is expressed by photoreceptors in Xenopus laevis retina. Murine macrophages (RAW 264.7) pre-incubated with CNI-1493 prior to activation with lipopolysaccharide (LPS)/interferon gamma (IFNgamma) had decreased NO production measured as NO(2)(-)/NO(3)(-) levels and reduction in inducible NO-synthase (iNOS) expression.
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The study of tuberculous infection in Hellenic army recruits for the purposes of BCG vaccination, which with chemoprophylaxis and early case-finding are the major strategies used for preventing tuberculosis (TB). Age-dependent differences in survival after severe burns: a unicentric review of 1,674 patients and 179 autopsies over 15 years. Association of 11q loss, trisomy 12, and possible 16q loss with loss of imprinting of insulin-like growth factor-II in Wilms tumor. In this report, we show that RAP binds to lipoprotein lipase (LPL) and may play a role in the maturation of LPL. In this report, we demonstrate that SIII stimulates promoter-specific transcription by increasing the overall rate of RNA chain elongation by RNA polymerase II. Similar membrane ruffling was induced by other growth factors such as insulin, IGF-I, acidic or basic FGF but not by EGF or alpha- and beta-TGF, only in TR4 cells. Middle-aged subjects had smaller WM scores, a marginally slowed down recognition performance, and a smaller and delayed N400 component. Such conditions will remove the risk of anaphylactic shock at the point of reperfusion of the transplant. Comparison of manual and automatic section positioning of brain MR images. However, the use of fluorescent microscopy was unable to do this.
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Surgery for Wolff-Parkinson-White syndrome in the first year of life. Detection of keratin subtypes in routinely processed cervical tissue: implications for tumour classification and the study of cervix cancer aetiology. Ultrasound identification of the aneurysm was then possible and percutaneous embolisation was performed successfully. Strong immunoreactions could be demonstrated for pan-cytokeratin, but not for desmin or EMA. It is proposed that Actinomyces like Candida induces pseudoepitheliomatous hyperplasia of the mucosa of the tongue and inflammatory hyperplasia of the underlying connecting tissue, resulting in the characteristic elevated lesion. Paroxysmal slow waves and spike activity were recorded from implanted electrodes in amygdala, hippocampus, and cortex following higher doses of clozapine, but the EEG abnormalities were not correlated with the myoclonic jerks. Nitric oxide mediates the formation of synaptic connections in developing and regenerating olfactory receptor neurons.
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The enhanced DCF fluorescence was inhibited by a radical scavenger, butylated hydroxytoluene. xl-mtTFA was not required for basal transcription from a minimal mtDNA promoter, and this HMG box factor could not substitute for the basal factor, which is therefore designated xl-mtTFB. A non-significant trend in favor of Gd-EOB-DTPA-enhanced MRI with regard to characterization of hepatocellular carcinoma was found, although the CT scans were not optimized as the MRI scans. Based on results from several peptide-RNA model systems, we suggest that helical peptides may be used to recognize RNA structures having particularly wide major grooves, such as those found near loops or large bulges, and that nonhelical or extended peptides may be used to recognize less accessible grooves. TCDD promoted IL-8 secretion by HPMC-U937 co-culture, but exerted a contrary effect for IL-8 secretion when combined with estradiol. However, in population studies no clear distinction between normal and abnormal is found.
NFkappaB decoy oligodeoxynucleotides ameliorates osteoporosis through inhibition of activation and differentiation of osteoclasts. Antagonistic effects of retinoic acid and triiodothyronine in the expression of corticoid-binding globulin (CBG) by cultured fetal hepatocytes. The main outcome measures included lipid and lipoprotein levels and prevalence of metabolic syndrome. The association between the yearly rate of asthma deaths and consumption of these medications was estimated using Poisson regression. 16 patients with a contact dermatitis limited to the thighs where polyamide trouser pockets contact are described. Simultaneously, adequate insulin and antibiotic therapy is conducted.
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The purpose of this study was to characterize the electrophoretic patterns of human resting and stimulated whole saliva. Combinations of stem cell factor with other hematopoietic growth factors enhance growth and sensitivity to cytosine arabinoside of blast progenitors in acute myelogenous leukemia. Predictive anatomic features have been identified that aid patient selection. A baghouse test program for oxygen lanced open hearth fume control. This retrospective cohort study analyzed all operative vaginal deliveries at a university hospital in 1989 and 1990. Risk factors include female sex, young age, lower socio-economic study, separated or divorced, positive family history, stressful life events, certain medical illness and so on. The results of a comprehensive visual assessment will be related to the specific low vision devices and its use. The effects of estradiol and progesterone on food intake, body weight, carcass adiposity, and adipose tissue lipoprotein lipase (LPL) activity were investigated in weanling female rats. Current studies of the ecology and molecular biology of baculoviruses should further improve efficacy and better define safety.