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Lorivan (Lorazepam)
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Lorivan

Lorivan, an antianxiety agent, has the chemical formula, 7-chloro-5-(o-chlorophenyl)-1,3- dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one. It is a nearly white powder almost insoluble in water. Each Lorivan tablet, to be taken orally, contains 0.5 mg, 1 mg, or 2 mg of lorazepam. The inactive ingredients present are lactose monohydrate, magnesium stearate, microcrystalline cellulose, and polacrilin potassium.

Other names for this medication:
Almazine, Anxilor, Anxionil, Anxipose, Atipam, Biokalm, Biolar, Calmese, Dulozep, Larosh, Larpose, Lopam, Lopez, Loracalm, Lorakar, Loralite, Lorazam, Lorazepam, Lorazine, Loricon, Loripam, Lorivan, Lorpam, Lorvin, Lotweet, Nexlor, Norpose, Olraz, Trapex, Urpam, Zelor, Zepatrac, Zepnap

Similar Products:
Viramune, Flomax, Casodex, Bactrim, Revia, Theolair

Also known as: Lorazepam

Description

Lorazepam is a benzodiazepine (ben-zoe-dye-AZE-eh-peen) that is used to treat a seizure emergency called status epilepticus. Lorazepam injection is also used as a sedative to help you relax before having surgery.

Dosage

Usual Adult Dose for Anxiety:

Initial dose: 2 to 3 mg orally per day, given 2 to 3 times per day Maintenance dose: 1 to 2 mg orally 2 to 3 times a day Comments: -The daily dosage may vary from 1 to 10 mg/day. -The dosage should be increased gradually when needed to help avoid adverse effects. -When higher dosage is indicated, the evening dose should be increased before the daytime doses. -Use of anxiolytic agents is typically not needed to treat anxiety/tension associated with the stress of everyday life. -Clinical studies have not evaluated this drug for efficacy in long-term treatment (e.g., greater than 4 months). Uses: -Management of anxiety disorders -Short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms

Usual Adult Dose for Insomnia:

2 to 4 mg orally once a day at bedtime Comments: -The dosage should be increased gradually when needed to help avoid adverse effects. -Clinical studies have not evaluated this drug for efficacy in long-term treatment (e.g., greater than 4 months). Use: Management of insomnia due to anxiety of transient situational stress

Usual Geriatric Dose for Anxiety:

Older or debilitated patients: -Initial dose: 1 to 2 mg orally per day, given in divided doses Comments: -The dosage should be increased gradually when needed to help avoid adverse effects. -The daily dosage may vary from 1 to 10 mg/day. -When higher dosage is indicated, the evening dose should be increased before the daytime doses. -Use of anxiolytic agents is typically not needed to treat anxiety/tension associated with the stress of everyday life. -Clinical studies have not evaluated this drug for efficacy in long-term treatment (e.g., greater than 4 months). Uses: -Management of anxiety disorders -Short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms

Detailed Ativan dosage information

Overdose

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Lorivan can be fatal. Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, fainting, or coma.

Storage

Store Ativan at room temperature away from moisture, heat, and light.

Keep track of the amount of medicine used from each new bottle. Lorivan is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Side effects

The most common side effects associated with Lorivan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

The additive central-nervous-system effects of other drugs, such as phenothiazines, narcotic analgesics, barbiturates, antidepressants, scopolamine, and monoamine-oxidase inhibitors, should be borne in mind when these other drugs are used concomitantly with or during the period of recovery from Lorivan Injection.

Extreme caution must be used when administering Lorivan Injection to elderly patients, very ill patients, or to patients with limited pulmonary reserve because of the possibility that hypoventilation and/or hypoxic cardiac arrest may occur. Resuscitative equipment for ventilatory support should be readily available.

When Lorivan injection is used IV as the premedicant prior to regional or local anesthesia, the possibility of excessive sleepiness or drowsiness may interfere with patient cooperation in determining levels of anesthesia. This is most likely to occur when greater than 0.05 mg/kg is given and when narcotic analgesics are used concomitantly with the recommended dose.

As with all benzodiazepines, paradoxical reactions may occur in rare instances and in an unpredictable fashion. In these instances, further use of the drug in these patients should be considered with caution.

There have been reports of possible propylene glycol toxicity (e.g., lactic acidosis, hyperosmolality, hypotension) and possible polyethylene glycol toxicity (e.g., acute tubular necrosis) during administration of Lorivan Injection at higher than recommended doses. Symptoms may be more likely to develop in patients with renal impairment.

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Effect of intrafollicular indomethacin injection on gonadotropin surge-induced expression of select extracellular matrix degrading enzymes and their inhibitors in bovine preovulatory follicles. Patients who receive surgery for pediatric cataracts are at very high risk of developing ocular hypertension and glaucoma. Side effects of the most commonly used primary antituberculosis (anti-TB) drugs may be mild as well as fatal. Integration of instruction in medical microbiology, virology, and immunology with other disciplines of a therapeutic faculty. In addition, a concomitant increase in glomerular expression of transforming growth factor beta 1 (TGF-beta 1) mRNA was observed. Its potential as a therapeutic tool for RET-positive thyroid tumors, including those expressing V804 mutations merits study. Differential changes in gene expression in motor neurone disease. In particular, our approach provides a solution for the straightforward definition of target and trepanation points for the purposes of stereotactic neurosurgical operation, and an exact testing of its result.

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Previous selective strategies targeting high risk groups for immunization have failed to prevent the significant morbidity and mortality associated with hepatitis B virus infection. The walls of these tubes are composed of rod-like features which we have interpreted as columns of individual alpha-helices stacked end-to-end. Isolation of viruses from female Culex tritaeniorhynchus in Aedes albopictus cell cultures. A phylogenetic analysis of the HU-type proteins (HU and IHF) is presented, and a scheme for the origin of the hup genes and the onset of HU heterodimericity is suggested. Congenital brain tumor in neonate--case report and review of literature. Clinical trials on thiomucase, a spreading agent (preliminary note). We were unable to demonstrate rearrangement of the ETS1 gene in this group, thus confirming that the 11q23 breakpoint does not involve ETS1 protooncogene. Screening is necessary before specific invasive investigations are initiated. Small fragments of micro-organisms which elicit protective immune responses have now been identified for several disease-causing agents.

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Accumulation of ganglioside Gm2 in cerebrospinal fluid of a patient with the variant AB of infantile Gm2 gangliosidosis. These data suggest that NPY may change the value of food in ways that cannot be accounted for by changes in insulin, glucose levels or intracellular glucoprivation. The major chromatographic techniques (TLC, GC, HPLC) and combined detection systems for the determination of bile acids are critically evaluated and their advantages and disadvantages discussed. These children, whose mean (preoperative, unaided) average hearing level was 118 dB, were reported to perform at side effects of acarbose 50 mg the same level as nonimplanted children with average hearing levels in the range from 80 dB to 104 dB, depending on the outcome measure. The procedures for the initial and follow-up examinations were standardized.

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