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Lodine (Etodolac)

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Lodine is used to relieve pain from various conditions. It also reduces pain, swelling, and joint stiffness from arthritis. This medication is known as a nonsteroidal anti-inflammatory drug (NSAID). It works by blocking your body's production of certain natural substances that cause inflammation.

Other names for this medication:
Etios, Etobest, Etodolac, Etofree, Etogesic, Etomax, Etoron, Etosafe, Etova, Etura, Freeup, Penalgon, Proxym, Setolac, Toldin

Similar Products:
Prilosec, Exelon, Cenforce, Revia, Decadron, Arava, Propecia

Also known as: Etodolac


Etodolac is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain, and helps to relieve symptoms of arthritis (eg, osteoarthritis and rheumatoid arthritis), including inflammation, swelling, stiffness, and joint pain. However, this medicine does not cure arthritis and will help you only as long as you continue to take it.

This medicine is available only with your doctor's prescription.


Usual Adult Dose of Lodine for Osteoarthritis:

Immediate Release: -Initial dose: 300 mg orally 2 to 3 times a day or 400 mg to 500 mg orally twice a day -Maintenance dose: A lower dose of 600 mg/day may suffice for long-term use -Maximum dose: 1000 mg/day Extended Release: 400 mg to 1000 mg orally once a day Comments: -Therapeutic response can be seen within 1 week of therapy, however, is most often observed by 2 weeks; doses should be adjusted accordingly after satisfactory response is achieved. Uses: For acute and long-term use in the management of signs and symptoms of osteoarthritis and rheumatoid arthritis

Usual Adult Dose of Lodine for Rheumatoid Arthritis:

Immediate Release: -Initial dose: 300 mg orally 2 to 3 times a day or 400 mg to 500 mg orally twice a day -Maintenance dose: A lower dose of 600 mg/day may suffice for long-term use -Maximum dose: 1000 mg/day Extended Release: 400 mg to 1000 mg orally once a day Comments: -Therapeutic response can be seen within 1 week of therapy, however, is most often observed by 2 weeks; doses should be adjusted accordingly after satisfactory response is achieved. Uses: For acute and long-term use in the management of signs and symptoms of osteoarthritis and rheumatoid arthritis

Usual Adult Dose of Lodine for Pain:

Immediate Release: 200 mg to 400 mg orally every 6 to 8 hours -Maximum dose: 1000 mg/day Use: For the management of acute pain

Usual Pediatric Dose of Lodine for Juvenile Rheumatoid Arthritis:

Extended Release: 6 to 16 years: 20 to 30 kg: 400 mg orally once a day 31 to 45 kg: 600 mg orally once a day 40 to 60 kg: 480 mg orally once a day Greater than 60 kg: 1000 mg orally once a day 17 to 18 years: 400 mg to 1000 mg orally once a day Use: For the relief of signs and symptoms of juvenile rheumatoid arthritis

Detailed Lodine dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include drowsiness, vomiting, stomach pain, or stomach bleeding.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Lodine XL dosage information

Side effects

The most common side effects associated with Lodine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of etodolac in the elderly. However, elderly patients are more sensitive to the effects of etodolac than younger adults, and are more likely to have age-related kidney problems, which may require adjustment of dosage in patients receiving etodolac.

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Association between reported use of inhaled triamcinolone and differential short-term responses to aerosolized albuterol in asthmatics in an emergency department setting. The tissue was stained following the haematoxylin-eosin and van Giesson techniques. Correlation between susceptibility of infants to infections and interaction with neutrophils of Escherichia coli strains causing neonatal and infantile septicemia. The average titer of serum anti-HBsAg antibody in the mice immunized with HBsAg together with gp96 or its N-terminal fragment were much higher than those immunized with HBsAg alone detected by ELISA. To determine whether proteolytic cleavage of the S glycoprotein might be important for the newly emerged SARS-CoV, we introduced a furin recognition site at single basic residues within the putative S1-S2 junctional region. These structures were preserved by co-variations and compensatory mutations, as well as by additional complex rearrangements. The epithelial cells were cultured in the presence or absence of lipopolysaccharide (LPS), and the respective conditioned media were added to the cultures of PDL cells and GF.

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Humoral immune recognition of proteolipid protein (PLP)-specific encephalitogenic epitopes in the SJL/J mouse. Simple or association alterations of central origin of these three motor functions. In addition to new analytical results, in this work, we present a critical comparison between numerical and analytical computations. To determine the protein and mRNA expression of p53, p63, and p73 in central and peripheral human corneal endothelial cells. The metabolic pathways associated with FAME production in patients with impaired liver function remain to be identified. At birth there were two centres of ossification, one in the vertebral body and one in the base of each pedicle of the neural arch. On September 3, 2005, approximately 12,700 evacuees arrived in San Antonio and were housed in four primary evacuation centers (ECs). Two methods for improved venous access in acute leukemia patients. This is particularly evident ultram dosing adults in the hindbrain where overt segmentation occurs. Pup-killing behavior in mice: suppression by early androgen exposure.

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