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These include formation of carcinogenic N-nitroso compounds, direct deamination of DNA bases, and oxidation of DNA after formation of peroxynitrite and/or hydroxyl radicals. Although the neuroprotective effects of estrogens are well recognized, the exact mechanisms involved in the ability of these sex steroids to protect the cerebral tissue still remain unclear. Marked hyperinsulinaemia in postmenopausal, healthy Indian (Asian) women. We describe a case of digoxin intoxication due to an unadjusted loading dose in a patient with renal failure. Some studies suggest weight gain with insulin therapy, others contradict it.
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However, pulse sequence, echo time, and concentration of contrast agent have profound effects on the vessel size dependence of delta R2. Regulation of Chlamydomonas flagellar dynein by an axonemal protein kinase. Clinical, methodological and pharmacological problems may explain these discrepancies and are of great interest. Effect of reduced aprotinin dosage on blood loss and use of blood products in patients undergoing cardiopulmonary bypass. The assessment of the histomorphological characteristics of the arteria gastroepiploica dextra and its potential as an artery for myocardial revascularization.
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Crossed immunoelectrophoresis and other related quantitative immunoelectrophoresis techniques have been used to elucidate the antigenic complexity of a reference preparation of capsular extract, potassium thiocyanate extract, lipopolysaccharide, heat-stable antigens, and free endotoxin from Pasteurella multocida serotype 1. Therefore, it is recommended that non-parametrical method is used to analyze this data. (18)F-FDG PET/CT in the evaluation of recurrent ovarian cancer: a prospective study on forty-one patients. An example of the social-doctor problem is the mal distribution of doctors in rural areas. Pulmonary endothelial permeability in patients with severe lung injury.
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Thus, monoclonal antibodies to (a) the CH region of Ig (anti-mu and anti-allotype), (b) the C kappa region, (c) the V region (anti-idiotype) of surface IgM, as well as (d) multivalent antigen (2,4,6-trinitrophenyl-bovine serum albumin), all show similar effects and dose-response curves. Heat-denatured mitochondrial DNA renatured more readily than nuclear DNA. AA (0.5-16 microM) also induced an increasing release of the AA metabolite thromboxane B2 (TXB2). An interview was conducted using a modified questionnaire recommended by the American Thoracic Society for epidemiologic studies. Severe myocardial bridge on the anterior interventricular artery. A comparison of ion shifs with adenosine triphosphate and creatine phosphate levels in muscle. Pseudorabies virus as a transneuronal tract tracing tool: specificity and applications to the sympathetic nervous system. Removal of breast cancer cells from bone marrow by in vitro purging with ether lipids and cryopreservation.
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Fibrillin expression and localization in various types of carcinomas of the thyroid gland. Myocardial contractility was evaluated with the slope (Mw) of the regional preload recruitable stroke work relationship. Special attention should be drawn to hypomanic phases and phenomena as rapid cycling. Transfection studies indicated that 5E5 protein expressed in COS-1 is localized in cell nuclei. Investigation of the state of local thermodynamic equilibrium of a laser-produced aluminum plasma. The distribution of Kunitz-type inhibitors in different species of ruminants is compared and discussed on the basis of the expression of their encoding genes.
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The results of these experiments help us in refining existing models of visual-vestibular interaction, by providing a model which accounts for the phenomenon of oculogyral illusion. Inhibition of cytotoxicity of chicken granulocytes by serotonin and ketanserin. Tumors metastasized to the brain of wild type mice treated with EACA and plg-/- less efficiently than in untreated wild type mice. Heritability of left ventricular mass in a large cohort of twins. Pathology of JRA in Japan--Survey of autopsied as well as biopsied cases.
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The sonic and ultrasonic preparatory instruments form an exception in this respect due to their non aggressive way of shaping. Treatment with SB220025 increased also LPS-induced c-Jun N-terminal kinase (JNK) activity. Because the Cd-malate complex is relatively weak, we suggest that the complex forms inside the vacuoles as a result of an efficient tonoplast transport of Cd and a constitutively high concentration of malate in the vacuoles, and that the formation of the Cd-malate complex may lead to a decrease of subsequent Cd efflux to the cytoplasm. Ochratoxin a determination in beer by solid-phase microextraction coupled to liquid chromatography with fluorescence detection: a fast and sensitive method for assessment of noncompliance to legal limits. Southern blot of DNA obtained from alkaline lysates did not work as we could not obtain any signals in the filters. With regard to the functional specificity of tolerance induction, lymph node T cells derived from either GP-MBP-SP- or GP-68-86-SP-treated animals exhibited a marked reduction in both proliferation and production of Th1-derived cytokines (IL-2, IFN-gamma, and lymphotoxin/TNF-alpha) in response to either GP-MBP or GP-68-86 in culture.
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Deinstitutionalization has created a new type of patient--the new young chronic--who has received most or all of his treatment during brief hospital stays and through extended contact with outpatient community care programs. Fluoride concentration in saliva after consumption of a dinner meal prepared with fluoridated salt. Synthesis of a radioiodinated photoreactive MAGE-1 peptide derivative and photoaffinity labeling of cell-associated human leukocyte antigen-A1 molecules. Modifications induced by triiodothyronine on skin lesions caused by plexioroentgen irradiation. All tracheal lesions were anatomically located proximal to the stoma.
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The mean arterial pressure index in patients with atherosclerosis undergoing exercise therapy. Visualizing the pediatric airway: three-dimensional modeling of endoscopic images. Management of pituitary-adrenal suppression secondary to corticosteroid therapy. Alpha-2-macroglobulin as the major defence in acute pseudomonal septic shock in the guinea-pig model. Intensive monitoring of the usage of these new regulations facilitates health care policy making, including future planning. In summary, 8PN had very similar though milder effects than E2 on all tested parameters. Heart failure is basically a manifestation of mechanical disturbances of the heart, but not of electrical abnormalities and is not associated with specific ECG patterns. --Complete tubal occlusion, as a secondary cause of secondary sterility in the wake of therapeutic abortion, was recorded from 2.96 per cent of the above primigravidae. TD induces well-defined alterations in neurons, microglia, astrocytes, and endothelial cells.
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To describe the effect of a standardized rewarming protocol and acetaminophen on the following outcome variables: core temperature, peak core temperature, rewarming time, and hyperthermia. In DU145 cells, the apoptosis induction by PEITC was statistically significantly attenuated by pharmacological inhibition of JNKs with SP600125. Antithrombin III activity in the elderly--association with cardiovascular disease risk factors. Many filamentous fungi produce an array of extracellular enzymes that acting in cell walls release elicitors of the plant defense response These enzymes may therefore be important in biocontrol applications. Certain morphological alterations were observed in secretory tubules and epithelial cels of mammary glands. DNA repair occurs after dissociation of modified PARP from DNA strand breaks. These data indicate that PPARgamma regulates the development of the central nervous system during early embryogenesis via control of NSC proliferation.
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Core particles of serotype 10 have also been crystallized but the crystals have yet to be analyzed by X-ray diffraction. Inflammatory macrophages colocalize with BCP deposits in developing atherosclerotic lesions and in vitro can promote calcification through the release of TNF alpha. In so doing we propose that factors resulting in Type 1 diabetes be considered a result of environmental pathogenic selection (EnPS). Overall, the transvestibular procedure was thought to be technically difficult. Immunochemical methods show no detectable C3 in the serum of the affected dogs, and there is no evidence of an inhibitor of C3 in the serum. We report an unusual patient with a mediastinal bronchogenic cyst associated with rapid hemodynamic deterioration secondary to compression of vital structures. Mixed purine-pyrimidine oligodeoxynucleotides were designed to form collinear DNA triplexes with pyrimidine-rich elements in the EGFR gene promoter. In this study the authors developed new technics of study of duodenal absorption of calcium in rats: atomic absorption spectrophotometry, and dialysis to equilibrium. Satellite DNA sequences in the New World primate Cebus apella Plaatyrrhini, Primates).
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The counts at temperatures of 30 degrees C were significantly higher than at 25 degrees C. Favored models of spindle checkpoint signaling propose that two inhibitory complexes (Mad2-Cdc20 and Mad2-Mad3-Bub3-Cdc20) must be assembled at kinetochores in order to inhibit mitosis. Malignancies after marrow transplantation for aplastic anemia and fanconi anemia: a joint Seattle and Paris analysis of results in 700 patients. While surgical repair of tetralogy of Fallot has improved the long-term outlook for this patient population, sudden death late after repair remains a problem. This corresponded with, but lagged behind, the pattern of calpain activation determined using an antibody against calpain-cleaved alpha-spectrin.