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Sphingosine equally inhibited the activity of primase complexed with DNA polymerase alpha, as well as its free form, with a Ki value of 4 microM. Samples were collected as the first draw at the beginning of the work week. Disease: Ehlers-Danlos syndrome and periventricular nodular heterotopia. This report describes a toxicity testing procedure using the inhibition of dehydrogenase enzyme activity of Bacillus cereus as test parameter. Improvement and validation of an HPLC method for examining the effects of the MDR1 gene polymorphism on sparfloxacin pharmacokinetics.
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Total cytoplasmic RNA was analyzed by Northern blot and slot-blot hybridization to examine the prolactin mRNA level. Thus, the optimal ascertainment strategy in genetic association studies depends on the unknown underlying multilocus genetic model, and on whether the goal of the study is to detect an effect or to accurately estimate the resulting disease risks. Proposal for a new method for testing the drug sensitivity of tubercle bacilli by colony counting. GnRH and substance P regulate prostaglandins and sex steroids from reptilian (Podarcis sicula sicula) ovarian follicles and corpora lutea. Impact of vision on the development of topographical orientation abilities. The activity of the novel enzyme was decreased by the treatment with the anti-novel enzyme antibody, but not with the anti-classic enzyme antibody, and vice versa for the classic enzyme. A study on human dental embryology in an endemic high fluorosis region. Expression of L-selectin ligands in human endometrium during the implantation window after controlled ovarian stimulation for oocyte donation.
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In comparison to a three-hour first incubation, an overnight first stage incubation did not contribute to an improvement in the over-all clinical effectiveness of the test system. These results, taken together, suggest that HIV can induce antiviral cellular gene expression, independent of IFN. Biopsy samples were taken from six locations of the entire colon and from the terminal ileum in 10 patients with active total UC, 10 patients with inactive total UC, eight patients with active distal UC, and 11 control subjects. Although it is rare, a supratentorial VA, without associated cavernous angioma, may lead to intraventricular hemorrhage. For both types, multiple interacting nuclear genes were demonstrated. Use of adenosine-sensitive nondecremental accessory pathways in assessing the results of radiofrequency catheter ablation.
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The clinical signs and gross lesions were similar to those in goats. The dispersion of the hyperchromic effect in thermally induced transitions of nucleic acids. Seven p-terphenyl derivatives named terrestrins A-G together with three known ganbajunin B, thelephantins F and H, were isolated from the methanol extract of fruiting bodies of the Japanese inedible mushroom Thelephora terrestris (Thelephoraceae). An inverted insertion of a segment 7q22-q34 into 3q21 was found in a mentally normal male infant with ectrodactyly of a hand and the feet. Germline mutation analysis identified the C407T mutation, which has been related to a VHL phenotype in which pheochromocytomas are rare. In vivo methylation studies revealed that cells grown on palmitoleic acid produce 2.6 fold more phosphatidylcholine via the CDP-DAG (methylation) pathway than cells grown on oleic acid, although oleic acid facilitated the direct phosphorylation of exogenously supplied choline. Recognition of this distinctive clinical syndrome associated with LSD use might avoid unnecessary anxiety and excessive diagnostic tests for patients with this disorder. The desorption of the immobilized macromolecules from the azopolymer surface in an aqueous medium was observed to be very slow, on the time scale of 10 min to weeks, depending on the photoirradiation time. Reports in the literature also indicate acute liver intoxication, including a number of fatal cases.
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The efficacy of paired measurements for gastric or small-intestinal bacterial overgrowth is poor. All 12 eyes received an intravitreal injection of vancomycin hydrochloride, 1 mg, on development of the first signs of endophthalmitis. Italian Cooperative Study Group on the Epidemiology of Cluster Headache (ICECH). Frequently MRI data is characterised by a relatively low signal to noise ratio (SNR) or contrast to noise ratio (CNR). Successful legal complaint of a physician against a sentence by the Chief Finance Directorate. The effects of combined physical and psychological stress on cardiovascular and respiratory responses were examined.
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On the contrary, the electronic magnification on the monitor yields the same spatial resolution as non-magnified digital images (up to 4.3 lp/mm). Ecabet, an antiulcer drug, is reported to be effective in patients with ulcerative colitis. Attrition in randomized controlled clinical trials: methodological issues in psychopharmacology. Our experiments demonstrated that calreticulin, like calnexin, associated transiently with numerous newly synthesized proteins in the endoplasmic reticulum. Tumor cells were negative for markers of epithelial, muscular, neural, histiocytic, melanocytic, and vascular differentiation. Emergency assessment of severity in iron overdose by clinical and laboratory methods. By comparing the V3 sequences of virus gp120s able and unable to bind 19b, we were able to define the canonical 19b epitope as -I----G--FY-T, where residues at the positions indicated by the gaps do not contribute directly to the 19b-binding site. Enhancement of splenic glucose metabolism during acute malarial infection: correlation of findings of FDG-PET imaging with pathological changes in a primate model of severe human malaria. Lymphoid cells in the spots could take up very small amounts of HRP just after HRP injection, whereas lymphocytes showed no HRP uptake.
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Developmental genetic basis for the evolution of pelvic fin loss in the pufferfish Takifugu rubripes. Pore-forming bacteriocins of gram-positive bacteria and self-protection mechanisms of producer organisms. However, PBSC which contain a large number of T cells represent a potential risk for graft-versus-host disease (GVHD) in allogeneic (allo) transplantation. The place of bronchoscopy in the therapy of dyspnea due to respiratory insufficiency. Simultaneous amplification of wild-type and variant GR mRNAs indicates that the variant GR is more highly expressed in cells that are resistant to glucocorticoids. These results suggest that cellular proteins of 55KDa might be potential substrates of Tec in vivo. Surfactant delayed the absorption of furosemide but did not alter the fraction absorbed. One hundred one acute and chronic renal failure patients requiring subclavian venipuncture and catheterization.
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Platyfish and swordtails: a genetic system for the analysis of molecular mechanisms in tumor formation. A solitary massive tumor developed in the left eye of a 61-year-old female who had a history of insulin-independent diabetes mellitus for 20 years and whose left eye had become blind due to repeated anterior uveitis in the recent several years. These differences may be helpful in identifying the predisposing genes in familial patients with JIA. Comparison of two different methods for the vitrification of hatched blastocysts from the dromedary camel (Camelus dromedarius). Pain ratings were measured on a visual analog scale at 10-second intervals over 2 minutes of thermal pain stimulation. Increasing interest in the well-known activity of sulbactam against the genus Acinetobacter has been aroused. Luciferase assays, RT-PCR, cell proliferation, alkaline phosphatases assays, staining procedures, TUNEL assays, and caspase activity assays were performed to study the chondrocyte response to overexpression of Rac1 and Cdc42 proteins. A colourimetric dye assay to detect anti-viral activity of interferons: sensitivity for measuring cellular responsiveness to interferons.
A highly efficient polyethylene glycol-mediated transformation method for mushrooms. In general, there were cortisol increases over base to the procedures. At 1 year, variable degrees of incontinence for a liquid stool persisted in 7 of 9 patients who had low fistulas with a low anastomosis at dentate line level. For the surgical treatment of these defects we proposed (1989) a technique of contrarotation of the tunica albuginea which was later abandoned because it was too invasive. In this position three important anatomical points--the left and right anterior superior iliac spines and the upper medial point of the pubic bone--form one frontal plane. Isoprenoids targeted to the inhibition of the isoprenylation of oncogenic forms of ras proteins may offer a novel approach to chemotherapy. Systemic activation of coagulation may occur in a variety of disorders, including sepsis, severe infections, malignancies, obstetric or vascular disorders, and severe toxic or immunological reactions. Permanently transfected cell-lines expressing varying levels of alkaline phosphatase were established. Stroke volume was derived from the dynamic PET data according to the Stewart-Hamilton principle and, furthermore, cardiac efficiency using the work metabolic index. The culture supernatants of HK cells had costimulatory activity on the proliferation of anti-mu- or anti-CD40-activated B cells, and the activity dramatically increased after 12-O-tetradecanoylphorbol 13-acetate stimulation.