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Hoffman modulation contrast microscopy was used to develop a reliable method for sorting and collecting viable isolated retinular cells for morphological and electrophysiological studies. During contractions to carbachol, cooling evoked contractions in bronchi with epithelium but relaxations in those without epithelium. Large proportions of drug users are found in criminal justice, primary health, and welfare agencies. The sex ratio of families with ND children was not significantly biased toward boys as compared to the sex ratio of families with non-ND children, provided that the index ND child was excluded from the analysis. We applied Ad2/CFTR-1 to intrapulmonary airway epithelia of cotton rats and nasal epithelia of Rhesus monkeys. High frequency ultrasound imaging appears to be a valuable adjunct in making or corroborating the diagnosis of pupillary block glaucoma. Neither repair of the volar plate nor prolonged immobilization is necessary. Cells transfected with transferrin receptor cDNA lacking the iron regulatory domain become more sensitive to the DNA-damaging action of oxidative stress. There was a weak but significant correlation between the values of PDA and DA sulfate measured in the same specimens, but DA sulfate was more susceptible to impaired renal function. Since CFTR codes for a secretory Cl- channel, these data probably reflect the changes that occur in the lung transition from a fluid-secreting to an absorbing organ.
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Influence of atropine on the depletion of vasoactive intestinal peptide, substance P and calcitonin gene-related peptide from rat parotid gland in response to parasympathetic nerve stimulation. Venous malformations are a common form of vascular anomaly that cause pain and disfigurement and can be life threatening if they involve critical organs. Comparison of the results from the two studies showed that the median peak pressures demonstrated similar patterns with the highest pressure in the forefoot under the second/third metatarsal heads and the toes taking gradually reduced pressure from the first to the fifth toe. This study serves to prevent spurious interpretation of AP-conjugate based binding assays, be they against purified lipids/lipid mixtures or tissue samples from which lipids have not been removed. meliloti has been proposed, whereby FixL acts as an oxygen sensor as the initial event in the cascade and transmits this information to FixJ. Perioperative stimulation of erythropoiesis with intravenous iron and erythropoietin reduces transfusion requirements in patients with hip fracture. Because the short- and long-term effects of CT treatment are not the same, the actions of CT are time and concentration dependent. These results confirm C/EBP isoforms expression in intestinal epithelial cells. Before loading, the bond system in combination with acid etching the dentin provided superior results.
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Regulation of cytochrome P450 gene expression in human colon and breast tumour xenografts. Another 206 fragments varied as to their presence among individuals, but their relatedness to other fragments was not established. Evaluation of a single dose versus a divided dose regimen of amoxycillin in treatment of Actinobacillus pleuropneumoniae infection in pigs. After 6 weeks, the patient was asymptomatic, neurologic examination was normal, and the brain MRI showed only surgical cavitation. A promoter mapping immediately upstream of the dra gene was identified, and downstream of the pdp gene the nucleotide sequence indicated the existence of a factor-independent transcription terminator structure. Animals were sacrificed at 2, 6, 18, 28 and 105 days after the surgical procedure and paraffin-embedded hearts were subjected to peroxidase immunohistochemistry. Biological networks and analysis of experimental data in drug discovery. In patients with intermittent AV block and dual chamber pacemakers, a long paced AV interval of 200 msec or more can be selected to prolong pulse generator life (by avoiding the ventricular pace output) and to enable a more physiological and hemodynamically superior activation sequence.
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The unusual discovery of associated cranial and postcranial elements from a single Middle Pleistocene fossil human allows us to calculate body proportions and relative cranial capacity (encephalization quotient) for that individual rather than rely on estimates based on sample means from unassociated specimens. The timing of vitrectomy did not influence visual acuity outcomes. It was concluded that chlordiazepoxide, given in this recommended daily dose, did not potentiate what was considered a social quantity of alcohol. A significant increase for specific causes of death was obtained only for neoplasms of unknown origin. Furthermore, as a corollary to the observation that pretreatment with anti-Ia serum markedly reduced the immunogenicity of bone allografts, we conclude that much of the immunogenicity of bone allografts is attributable to a population of Ia-positive cells.
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The predicted IOL power was incorrect, as the patient had worn contact lenses during the preoperative assessment. Physicians involved in the care of patients with cardiac and vascular problems regularly employ heparin in treatment regimens of inpatients and outpatients. From the above data, we are induced to think that CLA may trigger apoptosis in the estrogen unresponsive MDA-MB-231 cell line via mechanisms involving above all the mitochondrial pathway. A monogenic senility syndrome segregating with longevity in mice. 2-Menaphthylmercapturic acid was isolated from rat urine after administration of 2-menaphthyl chloride, S-(2-menaphthyl)-l-cysteine and S-(2-menaphthyl)-glutathione, and was detected chromatographically after injecting 2-menaphthyl bromide. Urinary undiversion in myelomeningocele patients with an ileal conduit diversion. Namely, when human dermal fibroblasts and microvascular endothelial cells were seeded on the bottom of an inert filter and subsequently epidermal cells were seeded on top of it, fibroblasts produced extracellular matrix throughout which numerous branched tubes were spreading three-dimensionally. The objectives of the current study were to compare genito-urinary (GU) and gastro-intestinal (GI) toxicities as well as biochemical control (bRFS) in prostate cancer, utilizing conventional (2.0 Gy daily) (STD) or hyperfractionated (HFX) conformal irradiation (CRT). In contrast, respiratory burst, measured by nitroblue tetrazolium dye reduction, increased after OTC exposure, but only at high concentrations (500 and 1,000 micrograms/ml) of OTC.
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Adhesion of bacteria and of metastasizing tumour cells have much in common, especially the participation of lectins in this process. Antagonists of pre-anesthetic medication current state of the problem. AML: immunophenotypic heterogeneity and prognostic significance of c-kit expression. 24 hours after pancreaticography some of the animals still manifest high-grade hydropic damage to the ductal epithelium, including rupture of the apical cell-membrane focal lysis of cytoplasm, irreversible mitochondrial lesions and initial degeneration of the nucleus. Mass spectrometric identification of modified urinary nucleosides used as potential biomedical markers by LC-ITMS coupling. Muscle contraction: are the crossbridges independent force generators?. The aim of this study was to describe the pathophysiological changes in a model of dilated cardiomyopathy in turkey poults and to compare them to results obtained from failing human hearts. Sensitization of homologous and heterologous macrophages by cytophilic antibodies: inhibition of sensitization by normal serum. The abilities of platelet-derived growth factor (PDGF) and insulin-like growth factor (IGF-I) to regulate cAMP metabolism and mitogen-activated protein kinase (MAP kinase) activity were compared in human arterial smooth muscle cells (hSMC). Gentamicin-loaded microspheres for treatment of experimental Brucella abortus infection in mice.
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Brain metastasis of testicular yolk sac tumor with massive hemorrhage: case report. Candidate vaccine antigens that stimulate the cellular immune response of mice vaccinated with irradiated cercariae of Schistosoma mansoni. Firstly, analyzed the anti-proliferation effect of DHA on K562 cells and assessed the inhibitory effect on expression of VEGF in K562 cells. Pneumatic retinopexy is a procedure for reattaching the retina by injecting an expanding gas bubble and using either laser or cryopexy. There is no evidence of tumor transmission by transplantation of corneas from donor eyes with primary choroidal melanomas. All four had persistent disorders, and two had difficulties with mother/infant attachment. The plan for the future is to find therapeutic strategies that are specific for patients based on the specific biology of the disease.
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The role of gastric reflux in heartburn and diseases of the esophagus. The objective of this study was to define the optimal length of PEG chains to obtain the best tissue preservation. The screen which does not require elaborate continuous flow equipment nor special gas phase detects the activity of those compounds known to be effective against the parenteral stages of the parasite in mice. Preoperatively, sedation was observed in both groups, but children receiving OTFC had significantly less distress at time of separation from parents. However, the nature of these complexes and details of the molecular interactions are not fully understood. Effects of in vitro supplementation of bovine mammary gland macrophages and peripheral blood lymphocytes with alpha-tocopherol and sodium selenite: implications for udder defences. This suggests either that WS and NF1 are allelic or that phenotypes arise from mutations in very closely linked genes. Relaxin levels in 7 women with posterior pelvic and lumbar pain were also measured.
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We propose a possible antioxidant mechanism of action for lutein and lycopene that leads to formation of the oxidation products of these promising chemopreventive agents. In spite of the resulting potential for autocrine growth of Tera 2, we failed to observe such a situation. Lung cancer cell line CALU-1 was seeded on this artificial membrane and cell invasion was studied using the Fourier transform infrared (FTIR) imaging technique. Loco-regional treatment for esophageal cancer with bleomycin adsorbed to activated carbon particles. Demographic modeling methods were applied to data from a variety of sources, including surveys of mentally ill adults receiving public mental health services in New York State and demographic statistics on the general state population. Partial cDNA cloning and NGF regulation of a rat 5-HT3 receptor subunit. Consistent with the Na,K-ATPase cytoplasmic domain as being necessary for alpha/alpha interactions, the full-length alpha-subunit stably associates with an alpha N-terminal deletion mutant (delta Gly2-Leu273), but not with an alpha cytoplasmic deletion mutant (delta Arg350-Pro785). A total of 544 strains were studied (199 gonococci from male patients attending hospitals in the county of Avon, 204 unselected N gonorrhoeae isolates from male patients in Leeds, 20 strains referred to the Gonococcus Reference Unit because of difficulties with the Syva fluorescent antibody test (FAT), and 121 strains collected over a four year period which had not reacted with serotyping antibodies). ELC possess a light cytoplasm containing two types of granules: (i) numerous small granules, 50-110 nm in diameter, and (ii) single large granules, 290-860 nm in diameter. We have used the metamorphosis of the holometabolous insect, Manduca sexta, as a model to study effects of 20-hydroxyecdysone on the maturation of thoracic neuron membrane channel expression.
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Oligodendroglioma, ependymoma, choroid plexus papilloma, pituitary adenoma, and meningioma cells showed the same integrin pattern as their normal counterparts. Pediatric lung transplantation: expanding indications, 1985 to 1993. After giving their interpretation, they were informed of the correct meaning. The climate change scenarios used in this research are severe by climatological standards. Reverse redistribution on planar thallium scintigraphy: relationship to resting thallium uptake and long-term outcome. Patients with schizophrenia have long been observed to perform poorly on the Wisconsin Card Sorting Test (WCST). End stage renal disease requiring renal replacement therapy is a common complication of several renal diseases that are seen in the tropics.
Electron microscopy showed many lipid droplets in the cytoplasm, but no Langerhans granules. The aim of this study was to evaluate the 10-year clinical experience of this procedure in our institution. Patients without contraindications receive anticoagulation therapy immediately for documented lesions. They started to appear from 6 months onward, with increasing frequency with longer follow-up. Intradermal injection of bovine articular type II collagen produced, as expected, joint lesions in rats. Purification and characterization of hyaluronan from synovial fluid. Both ammonia-lyases have a catalytically important electrophilic group, which was believed to be dehydroalanine for 30 years but has now been revealed by X-ray crystallography and UV spectroscopy to be a highly electrophilic 5-methylene-3,5-dihydroimidazol-4-one (MIO) group. Although stem cell research has often focused on mammary development, mammary stem cells seemingly provide the basis for mammary growth and cell turnover in the mature animal. In Estonia, over the past half century, health and social policy was dictated by the Soviet socioeconomic system.