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Damadol (Tramadol)

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Damadol is used for the management of pain in adults. Although it's a little weaker than other opioids, it can still be addictive and habit-forming. Damadol is available as both an immediate-acting tablet and an extended-release tablet.

Other names for this medication:
Acupain, Arodol, Arrestadol, Bolodol, Damadol, Dolex, Doltel, Haledol, Ibudol, Movon, Omodol, Ospidol, Postadol, Redimol, Sedate, Topspas, Traceta, Tramacip, Tramak, Tramol, Trectadol, Typhon, Ultracon, Ultrazac, Unidol, Victadol

Similar Products:
Pyridium, Seroquel, Prometrium, Soma, Dilantin, Lipitor, Acticin

Also known as: Tramadol


Ultram ER is an pain medicine similar to an opioid. This medicine is used to treat moderate to severe pain.

The extended-release form of tramadol is for around-the-clock treatment of pain. This form of tramadol is not for use on an as-needed basis for pain.


Usual Adult Dose for Pain:

Adults (17 years or older): 50 to 100 mg orally every 4 to 6 hours as needed for pain -For patients not requiring rapid onset of analgesic effect: Initial dose: 25 mg orally once a day; titrate in 25 mg increments every 3 days to reach a dose of 25 mg four times a day; thereafter increase by 50 mg as tolerated every 3 days Maximum dose: 400 mg per day.

Usual Adult Dose for Chronic Pain:

Extended-Release (ER): 18 years or older (tramadol-naive): 100 mg orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day For patients CURRENTLY receiving Immediate-Release (IR) Ultram: Initial Dose: Calculate 24-hour IR requirement and initiate with a total daily ER dose rounded down to the next lowest 100 mg increment orally once a day Conversion from OTHER Opioids: Discontinue all other around the clock opioid drugs prior to initiating therapy -Initial dose: 100 mg ER orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day.

Usual Geriatric Dose for Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Geriatric Dose for Chronic Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Pediatric Dose for Pain:

Ultram is not recommended for use in pediatric patients 17 years or older: See Adult Dose.

Detailed Ultram dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Damadol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Ultram if you are allergic to tramadol, or if you have:

severe asthma or breathing problems; a stomach or bowel obstruction (including paralytic ileus); if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications; or if you have used an MAO inhibitor in the past 14 days (such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine).

Ultram should not be given to a child younger than 12 years old. Ultram ER should not be given to anyone younger than 18 years old.

Do not give Ultram to anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids.

Seizures have occurred in some people taking Ultram. Your seizure risk may be higher if you have ever had:

a head injury, epilepsy or other seizure disorder; drug or alcohol addiction; or a metabolic disorder.

To make sure Ultram is safe for you, tell your doctor if you have ever had:

breathing problems, sleep apnea; liver or kidney disease; urination problems; problems with your gallbladder, pancreas, or thyroid; a stomach disorder; or mental illness, or suicide attempt.

If you use tramadol during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.

Ask a doctor before using tramadol if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.

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The discovery of genetic exchange in African trypanosomes belonging to the Trypanosoma brucei group is an important development in our understanding of these organisms. These findings from different animal models as well as in clinical trials lead to the hypothesis that tetrahydrobiopterin, or a precursor thereof, could be a new and an effective therapeutic approach for the improvement of endothelium function in pathophysiological conditions. Apoptosis of CD4 and non-CD4 T cells in the pleural space occurred in both HIV/TB and TB. Redox Activity of Copper(II) Complexes with NSFRY Pentapeptide and Its Analogues. We describe a case of visceral leishmaniasis in a 15-month-old German child. Changes in the blood concentration of trace elements in rheumatism and other internal diseases. Respondents did not deal with the simulated ethical problems in a uniform manner and often tended to respond more to specific details of a case rather than the overall ethical dilemma posed. Substitution of an enzymatic peroxide-generating system for PMN did not alter the effect of colostrum. The mutator phenotype suggests that the wild-type RAD3 gene product may be involved in the maintenance of fidelity of DNA replication in addition to its known role in excision repair.

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In eyes with primary OAG that are receiving maximally tolerated medical therapy, SLT was found to be as effective as ALT in lowering IOP over a 5-year period. Results of blind testing a method to detect carriers of the Duchenne muscular dystrophy gene. We report here that reduced pyridine nucleotides and reduced glutathione result in an oxidation of Amplex Red by dioxygen that is dependent on the presence of horseradish peroxidase (HRP). Tamm-Horsfall glycoprotein (THG) released into the media was measured by radioimmunoassay and at the end of each experiment the slices were homogenized and assayed for THG content. In an eye with a proton beam-irradiated malignant melanoma of the ciliary body a second melanoma appeared episclerally on the opposite side of the globe. When esophageal perforation caused by EMR is immediately recognized, endoscopic application of metallic clips is appropriate therapy. Our aims were to study the timing of AR and factors affecting AR in children with CH. However, bud emergence was delayed to G2 during transition to the stationary phase, and in the early stationary phase budding scarcely occurred, although roughly half of the cells completed DNA synthesis. They were divided into control (20 patients) and test groups (20 patients) randomly.

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Thus, an increased local level of MCA is a feature of cancers with high inflammatory cell infiltration, and the presence of an in vivo concentration gradient of MCA suggests the direct role of this biologic activity in recruiting blood monocytes to the cancer site. Synergistic effects of maternal malnutrition and infection on the infant. Dental enamel defects, caries experience and oral health-related quality of life: a cohort study. Illness caused by a Barmah Forest-like virus in New South Wales. Venous sample two was transported in a tube containing FE (without ice) (customary practice). A moderately mentally retarded woman learned coin equivalences (with 5-, 10-, and 15-cent values) via matching to sample. As with gold, platinum and diamonds, it owes its value to a demand based on ritual, fashion and scarcity.

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The value of MRI for pre-operative evaluation of the rotator cuff is proven. Anesthetic agents which may activate complement or may be hepatotoxic are to be avoided. Results of a previous study using renal cell carcinoma (RCC) as a model pointed towards cancer-related features, which could be visualized as three groups by microarray based gene expression analysis. Differential effects on the hepatitis C virus (HCV) internal ribosome entry site by vitamin B12 and the HCV core protein. Standardized hepatitis C virus RNA panels for nucleic acid testing assays.

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Left anterior, lateral, and posterior views on 50 consecutive RES-lung scams were examined. Lower concentrations were effective in generating conductances in epithelial cells than in bilayers. Report of two cases with isolated stenosis at the bifurcation of the common femoral artery. US Justice Department appeals against the rulings that banning partial birth abortion is unconstitutional. The basic rules governing the folding of small, single-domain proteins are being discovered. Here we review the reasons for the hitherto partial HSV vaccine success and align these with our current knowledge of how natural HSV immunity develops. Micromorphological characters by which there species are distinguished include interspecific inversions, different sets of intraspecific inversions, different sets of sex chromosomes and a few micromorphological features other than the banding pattern. Mouse strains which develop tumors at a high incidence with characteristics very similar to human cancers have been derived over the last 8 years. The present study describes the findings of retrospective autopsy findings of 158 patients with AIDS which revealed infectious diseases from a time period before the use of highly active antiretroviral regimen. In depressed patients, a significant relationship between strong LDAEP, indicating low serotonergic function, and a favorable response to SSRI has been found.

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Seeds were exposed to ambient rainfall at the wetter high-elevation garden. 7 of 22 children were found to have developed a stricture of the ileal loop. To reveal the genetic interaction of Sox7, another Sox member, with Sox17 in developmental angiogenesis and their functional relationship with VEGF signaling. In animals the antibodies specific for the 44-68 were the most sensitive of the 3 types. To examine the value of continuous cardiac output monitoring for predicting those at risk, 40 consecutive patients were monitored using Doppler-derived cardiac output. Estimation of blood loss caused by Ancylostoma caninum in dogs using 51-CR-labelled red cells. Recognition of simian virus 40 T antigen synthesized during viral lytic cycle in monkey kidney cells expressing mouse H-2Kb- and H-2Db-transfected genes by SV40-specific cytotoxic T lymphocytes leads to the abrogation of virus lytic cycle. Patient 4: man, 60 years old, with HHC diagnosed in 1981, who referred fever in 1996 related to an abscess of the HHC.

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Postoperative analgesia for the ambulatory surgery patient is frequently inadequate. Confirmation of this hypothesis was obtained by amino acid composition of the major immunoreactive peptides produced by thermolysin digestion of human basic protein and isolated by high-performance liquid chromatography. This raises a puzzle: why has evolution left us vulnerable to anxiety disorders?. Investigations were made into the effects of crude and pure preparations of cholera toxin on the release of prostaglandin-like substances (PLS) from rabbit ileum. Atrial appendage aneurysm is a rare cardiac disease and may be complicated by embolic events and rhythm disturbances. Retinoic acid is essential for normal development and growth of structures such as head and limbs, and it can act as morphogen or teratogen. RNA editing of atp6 transcripts from male-sterile and normal cytoplasms of rapeseed (Brassica napus L.). Experimental studies on renal blood circulation after unilateral nephrectomy. Electron microscopic study of the thick hairs of dogs (but not the tiny hairs of rodents) reveals intricate infoldings of non-keratinized and keratinized cells. Partial pressures of oxygen and carbon dioxide in bone and their correlation with bone-blood flow: effect of decreased arterial supply and venous congestion on intraosseous oxygen and carbon dioxide in an animal model.

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Migration of porous coated acetabular prostheses fixed with screws: roentgen stereophotogrammetric analysis. Ma adam va-teda-ehu: halakhic criteria for defining human beings. Effect of irradiation on the properties of pollen in Austrian and Scotch pines. Nasal natural killer cell lymphoma presenting as lethal midline granuloma. It is thought that many more cases of SSPE occur in Saudi Arabia and also in many other tropical countries than are currently recognized. The radioactive microsphere technique appears to provide a means for reasonably reliable ovarian blood flow measurements in laboratory animals.

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However, three months after her initial hospitalization, we found that the lesions were probably secondary to self-injection with a chemical agent rather than a result of insulin allergy. It is concluded that the use of maternal plasma or serum AFP in the early detection of low birthweight babies is optimal in the period most suitable for screening for fetal neural tube defects. Macrophage depletion was carried out by the administration of liposome-encapsulated dichloromethylene diphosphate (Cl(2)MDP), 4 days before MRSA injection. Intravenous administration of hPTH1R or green fluorescence protein-tagged hPTH1R in pcDNA3 resulted 3 wk later, in generalized expression of hPTH1R (mRNA and protein), especially in vessels, liver, heart, kidney, and central nervous system, where it is expressed physiologically. Application of benzo(a)pyrene and coal tar tumor dose-response data to a modified benchmark dose method of guideline development.

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On the syndrome pathogenesis of cerebral arteriosclerotic psychoses. A multifactorial disperse analysis, using Statistica 6 for Windows (StatSoft), was applied for prognostication of risk for the infectious complications occurrence while a simultant operative interventions conduction for biliary calculous disease. Twenty to 25 min after entry, EGF, but not TF, appeared in a second clathrin-associated compartment. Furthermore, our results suggest a linkage of the biochemical events underlying ouabain resistance and expression of differentiation phenotypes in the mouse neuroblastoma cells. In 12 patients, BM biopsies were taken before and after splenectomy. To investigate the prevalence, persistence and genome heterogeneity of transfusion-transmitted (TTV) in HIV-1-infected patients, a group at high risk both of contracting blood-borne viruses and having viral persistence relating to immunodepression. This inflammatory response does not abate after smoking cessation, and in this cross-sectional study, appears to be independent of the presence or absence of emphysema, but related to destruction of the peribronchiolar alveolar attachments.

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Examination of these problems presents a solution by means of reinterpreting does biaxin treat a urinary tract infection the results. Our findings indicated that this mouse model is a useful system to study the physiological roles of Aurora-A and the genetic pathways of Aurora-A-induced carcinogenesis. Clinical evaluation--continuous real-time intra-arterial blood gas monitoring during anesthesia and surgery by fiber optic sensor. The insoluble glucan possessed strong glucan-associated glucosyltransferase activity even after extensive washing and lyophilization. A novel drill guide template was designed for atlantoaxial pedicle screw placement in this study. Palato-maxillary reconstruction by the angular branch-based tip of scapula free flap. In contrast, it was found that a branched (1----3)-beta-D-glucan is effective not only in either saline solutions of the triple helical sample or the lyophilized sample from DMSO, but also in DMSO solution. That applies also to the secondary immune response, in which course thiocyanate was not supplied. RsrII: a restriction endonuclease with a heptanucleotide recognition sequence.

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A mechanism for the ultrasonic effect is discussed in detail on the basis of the reaction pathway of the debromination of stilbenedibromides. Nineteen women and nine men with refractory genital warts were treated in an open-label, dose-response trial of intramuscular recombinant human interferon gamma. Evaluation of dressing protocols that reduce peritoneal dialysis catheter exit site infections. Under similar conditions of pH, fluorinated alcohol enhanced the intrinsic a-helicity of the protein molecule, whereas the addition of acetonitrile reduced the helical content. A concave area was artificially formed on the stacked lamellar crystals by the AFM tip. Quality of life impact of three different doses of suramin in patients with metastatic hormone-refractory prostate carcinoma: results of Intergroup O159/Cancer and Leukemia Group B 9480. Their remarkable clinical benefit has led to regulatory approvals in several malignancies including the genitourinary cancers, renal cell carcinoma, and urothelial carcinoma.

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The aim of this study was to assess the contribution of CGH to the unraveling of complex GTG karyotypes, which are difficult to evaluate by banding analysis, and to compare these results with those by CC and FISH. Ultrastructure of brain and neurosecretory cells in Catenulida (Turbellaria). Effects of baicalein on leukotriene biosynthesis and degranulation in human polymorphonuclear leukocytes. J G Du Verney (1684-1730): author of the first scientific account of the ear. If some medium is added on the third day this first exponential growth phase continues up to the eleventh day. Rheumatoid factors in serum and synovial fluid of the knee joint in reactive synovitis of local origin. Use of the weight efficacy lifestyle questionnaire with African American women: validation lamictal 25mg tab and extension of previous findings. Improved method for the absorption of streptococcal M and T antisera. This modification in the inflammatory response resulted in an accelerated loss of proteoglycan by the implanted femoral heads.

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Pathological pain, consisting of tissue injury-induced inflammatory and nerve injury-induced neuropathic pain, is an expression of neuronal plasticity. It seems that any beneficial effect of a substance P antagonist on functional outcome following TBI may be related to improvement in brain Mg homeostasis induced by the compound. Mild glial swelling, particularly of oligodendroglia, was noted at 12 hours and was obvious by 24 hours. The heterogeneity of isolated adult rat Leydig cells separated on Percoll density gradients: an immunological, cytochemical, and functional analysis. The average predrug myocardial clearance of Rb was 89.3 plus vantin medication name or minus 29.9 ml/min per 100 g myocardium. Renal dysfunction can be a common complication in patients with myotonic dystrophy 1. Since the family, not the individual, is the more important unit in Chinese culture, the model offers the opportunity for the total family to participate in changing dysfunctional individual and family patterns. with respect to lytically infected MOLT4 cells, suggesting that the defective expression of H and M proteins was not due to a restriction in the transcription of their mRNAs. Periodontitis is the most common chronic inflammatory disease caused by complex interaction between the microbial biofilm and host immune responses.

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Tryptophan 95, an amino acid residue of the Caprine arthritis encephalitis virus vif protein which is essential for virus replication. Examination of type-specific neutralizing antibody showed that the prevalent serotypes varied from year to year. When age was included in the model, this was the only variable predicting recall after 5 and 30 minutes, whereas age and hippocampus gave contributions in prediction of recall after several weeks. This work presents measurements of the polarization observables A(y), iT11, and C(y,y) in proton-deuteron elastic scattering. Additionally, such findings could potentially inform the development of personalized, early stages of quitting interventions for smoking cessation. To prevent lung edema, the left pump was controlled automatically to maintain the left atrial pressure below 20 mm Hg. When Triton X-100/EDTA extracts of the outer membrane of Escherichia coli K12 were passed through a column containing maltose-binding protein covalently linked to Sepharose 6MB beads, the phage lambda receptor protein or LamB protein was quantitatively and specifically adsorbed to the column and was eluted with a solution containing 1 M NaCl, but not with that containing 0.5 M maltose. CART and a multivariate logistic regression analysis (MLRA) were performed. False-negative results were encountered in seven patients (1.9 per cent) and false-positive results in two (0.6 per cent). Nine 40S and nine 60S ribosomal proteins cozaar generic version were bound to poly(U)-Sepharose.

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Bacteria isolated from fermented cucumbers were identified as Lact. Two-hundred-micrometer-thick, eosin-stained sections from these segments were analyzed by confocal laser scanning microscopy. Pregnancy may represent an immune complex-state if the presence of ICs represents a physiologic state, or an immune complex-disease if ICs occur under special circumstances only, such as in the EPH-gestosis syndrome. Preretinal neovascularization alone will be discussed, since other papers will examine the intra-and subretinal locations. Aminoacid composition and sequence of litorin, a bombesin-like nonapeptide from the skin of the Australian leptodactylid frog Litoria aurea.

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To examine the feasibility and clinical effects of a telephone counseling and medication monitoring program for adults starting treatment for depression in primary care. This increase in the promoter activity was not observed in a pho4Delta mutant or with a mutant UGP1 promoter that is devoid of putative Pho4 and Bas2 binding sites, suggesting that UGP1 expression is modulated by Pho85 through Pho4. The results of this study showed that in situ cross-linking of curcumin with collagen leads to the development of aerogels with enhanced physical and mechanical properties. Utilization of published right heart reference values in older adults seems to be problematic and in clinical practice, they always have to be interpreted within the clinical and functional context and in relation to other right heart echocardiographic parameters. Precipitation of a selenium deficiency by high dietary levels of copper and zinc. DNA repair genes involved in repair of the damages may be induced by growth stimulation. Cases were divided into those undergoing retrograde facial nerve dissection and those undergoing standard anterograde facial nerve dissection. Uterine uptake of alpha 2-macroglobulin and alpha 1-proteinase inhibitor from the blood during early implantation in the mouse. Recovery of herpes simplex virus from ocular tissues of latently infected inbred mice. Stromal tumors of the gastro-intestinal tract may require correlated immunocytochemical and ultrastructural studies for their identification: 9 of the 50 cases examined were positive with immunostaining for S-100 protein, and 16 tumors with epithelioid transformation did not show evidence of smooth muscle differentiation by electron microscopy.

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Liquid chromatography of porcine duodenal extracts, in conjugation with bioassay on guinea-pig ileum myenteric plexus longitudinal muscle preparation, yielded substances which inhibited electrically-evoked twitches uroxatral medication how long to take effect of the preparations, but whose actions could not be reversed by naloxone, an opioid antagonist. The identification and treatment of modifiable Ischemic stroke risk factors, in addition to appropriate antithrombotic therapy, can reduce the likelihood of first or recurrent stroke, prevent long-term morbidity and mortality after first stroke or transient Ischemic attack, and lower health care costs. The effects of surgery and radiation therapy of metastatic brain tumors from lung cancer. However, a recent study of VLBW children in 3 health maintenance organizations found no significant delays in immunizations. The positive inotropic effect was attenuated in part by propranolol, but not by either tetrodotoxin or imipramine.

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