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The IC, prepared in the form of an oil-emulsion, was administered intramuscularly. ir-Dynorphin A levels were significantly reduced in the hippocampus and in the striatum of kindled rats, as well as 5 and 60 min after kindled seizures, but they were increased back to control levels after 120 min. Individuals infected with HIV should be informed of their increased risk of acquiring these diseases and should be counseled on the recommended precautions. The investigation of patients who are unable to fixate the pattern visual stimulus generally requires the use of diffuse flash stimulation to elicit the visual evoked response. Changes in the endotheliocyte activity of the coronary vessels under the influence of stress.
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Immunohistochemical study identified enhanced caspase-3 expression in the cytoplasm and nuclei of airway and alveolar epithelial cells and vascular endothelial cells in rats with high VT ventilation, and the enhancement was especially obvious in the bronchial epithelial cells. We describe a method for generating a plasmid library expressing random truncations of a recombinant protein and for epitope mapping by screening the library with monoclonal antibodies. Boys had an increased risk for ADHD compared with girls, but only among siblings from antisocial families. It was concluded that norepinephrine exerted a favourable effect on right ventricular function. As shown previously, transforming growth factor (TGF)-alpha stimulated proliferation of type II cells in vitro. Relationship of components of papilloma virus to papilloma and carcinoma cells. The cylindrical organ can be broken down into three longitudinal regions arranged in an apical-basal order: stigma, style, and ovary. These findings support the hypothesis that after removal of trophic support, post-mitotic neuronal cells die due to an attempt to re-enter the cell cycle in an uncoordinated and inappropriate manner. GAP was readily phosphorylated on tyrosine by WT but not K269E Hck. DNA-dependent DNA polymerase induced by herpes virus papio (HVP) in producing cells.
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Determination of protein catabolic rate in patients on chronic intermittent hemodialysis: urea output measurements compared with dietary protein intake and with calculation of urea generation rate. Overexpression of 14-3-3sigma in both NPC cell lines reduced the tumor volume in nude mice, which could have significance for clinical application. It is unclear whether this unusually good articulation is linked to the ability of such persons to process speech signals containing energy that falls within the range of their residual, high-frequency hearing (for example, certain consonants). Overexpression of a surface-membrane permeability glycoprotein (Pgp) was identified in ovarian cancer of patients who had clinical multidrug resistance in 1985. Maximal temperature reduction by ipsapirone was significantly blunted in older subjects and was inversely related to age.
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Evaluation of susceptibility in macrophage and animal models is helpful because drugs concentrated in cells may be more efficacious against MAC--an intracellular pathogen--than would be predicted by results in cell-free systems. A diagnostic and prognostic tool for epidemiologic and economic analyses of dairy herd health management. Biliary sludge: necessity for a better distinction between crushable and noncrushable microconcrements. Such an involvement has been established in several animal models and in hypertensive patients. To describe and evaluate an application of sonography, transorbital color Doppler flow imaging of the carotid siphon and major intracranial arteries, and to compare it with transtemporal color Doppler flow imaging.
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The barrel-stave model as applied to alamethicin and its analogs reevaluated. An immunoconjugate, CD5 Plus, composed of ricin A chain and murine IgG1 anti-CD5 monoclonal antibody is under investigation for treatment of rheumatoid arthritis. Only type 4 photosensitivity (photoparoxysmal response, PPR) was considered in the study. After growth hormone treatment, expression levels of insulin-like growth factors-I and II, and growth hormone receptor were determined in the bone regenerate of the original defects. The role of endothelin-1 in regulating human granulosa cell proliferation and steroidogenesis in vitro. Moreover, the maintenance of this form of synaptic plasticity does not seem to require a sustained change in transmitter release.
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Crystalline eye degeneration as the 1st sign of plasmocytic myeloma. Liver and eye have previously been shown to be effective matrices for the detection of residual concentrations of the drug. Using a microinjection technique, we report here that HBx efficiently blocks p53-mediated apoptosis and describe the results of studies exploring two possible mechanisms of HBx action. Overexpression of myotonic dystrophy kinase in BC3H1 cells induces the skeletal muscle phenotype. This type of combined procedure offers both the benefits of extra capsular surgery: avoids neovascular glaucoma in diabetic patients, keeps silicone oil in good position, possible implantation in the capsular bag, and those of a small incision: absence of leakage, of myosis, of corneal clouding, rapid rehabilitation. Alloimmunization to Gm markers is common in rheumatoid arthritis, an allegedly autoimmune disease. Finally, molecular blockade of NF-kappaB (Ad5IkappaBAA) or p38MAPK (Ad5dnp38) signaling strongly inhibited enterocyte restitution. The re-endothelialization was followed by a return to normal fibrinolytic activity.
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Visual acuity deteriorates as a result of nystagmus, glaucoma, cataract, corneal opacities and retinal hypoplasia. Stereoscopic macroradiography was used to study the pattern of union of scaphoid fractures. The causal enzymatic defect, the virtual absence of fructose-1-phosphate aldolase, occurs in the kidney as well as in the liver of patients with HFI. Differential distribution of CaM kinases and induction of c-fos expression by flashing and sustained light in rat retinal cells. All virus polypeptide profiles consisted of 7--10 polypeptides of which two were glycosylated. It was hypothesized that percutaneous instillation of fibrin sealant is effective for the postoperative treatment of refractory donor-site seromas. Assessment of cerebrovascular risk profiles in healthy persons: definition of research goals and the Austrian Stroke Prevention Study (ASPS).
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Issues of the restoration treatment optimization of patients with locally spread extracerebral tumors (LSET) were discerned basing on analysis of 54 observations. The small reversible movements of the mammalian type I vestibular hair cells are discussed in terms of mechanical adaptation processes and morphological features. The aim of the current study was to investigate the effect of pre-treatment with SOD on the chemical mediators in hyperoxic lung injury. This paper deals with the organization, the data processing and some of the results obtained in Italian external quality assessment (EQA) schemes for hormones, tumor markers and hepatitis B markers. In a study of cervical injury in New Zealand rugby football in the years 1973 to 1978 inclusive, 54 cases of injury were identified of which five were fatal. Reaction mechanisms of the ultrafast photoisomerization between cyclohexadiene and hexatriene have been elucidated by the quantum dynamics on the ab initio potential energy surfaces calculated by multireference configuration interaction method.
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Enzymatic conversion of 32-oxygenated delta-7-lanosterol derivatives and of delta-8(14)-4,4-dimethyl-cholestenol to cholesterol. A computer program framework was established to enable a dairy herd production consultant to perform whole-herd analysis. However, this effect was not antagonised by p-aminobenzoate or folic acid. Short-term juvenile crowding arrests the developmental formation of dendritic spines on tectal interneurons in jewel fish. They were dominated by the representatives of the genera Penicillium, Paecilomyces, Trichoderma, and Rhizopus. Despite these deleterious effects of sleep deprivation, even on healthy subjects, intensive care patients are rarely permitted sufficient natural sleep. Human serum low-density lipoprotein protein: its conformation studied by circular dichroism. The accumulation of mesangial matrix is a common histologic abnormality observed over the course of various glomerular disease. Clinical trial of ethynodiol diacetate in a sequential oral contraceptive. As a model system for this study, we analyzed a chromatin-enriched fraction from the yeast Saccharomyces cerevisiae.
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The existence of immunolabeled neuropile in the zebrafish retinorecipient strata could be related to the turnover of retinotectal projections. The implications of this study are that monitoring of self-concept throughout the transitional period for new nurses can lead to early detection and appropriate intervention strategies thereby improving retention rates for new nurses. Novelty of the pyruvate metabolic enzyme dihydrolipoamide dehydrogenase in spermatozoa: correlation of its localization, tyrosine phosphorylation, and activity during sperm capacitation. Three-year outcome of family work in an early psychosis program. J chain and HNP-1 cDNA were amplified from the plasmids pCH-J and pBabeNeo-HNP-1 respectively, then the J-HNP-1 DNA fragment was obtained by recombinant polymerase chain reaction (PCR). These results also have implications for cardiac excitability under conditions, such as ischemia, where membranes are depolarized. We describe three novel human Anp32 proteins, reveal the evolutionary relationships of the members of the Anp32 family, provide insights into their biochemical and structural properties, and review their macromolecular interactions, substrate specificities, tissue distribution/expression patterns, and physiological and pathological roles. This article offers practical advice on which topic to select and on how to develop and implement guidelines.
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Atropine is no better than placebo in the treatment of biliary tract pain. Gestation day (GD) 12 mouse embryos and HEPM cells were used to test the hypothesis that the cell-cycle block induced by SAD results from a disruption of stage-specific regulatory components both in vivo and in vitro. The packing of the layers, however, is different for the two polymorphs. Vascular responses to smoking tobacco compared with responses to skin testing of tobacco extracts. CTP assessment of ROI surrounding an oxygen probe in the intraparenchymal brain tissue is feasible and showed a significant correlation between P(br)O(2) and MTT. In addition, this model can be useful for the development of meaningful therapeutic animal models. For purposes of comparison, another lesion was placed in area V1 in one animal. These studies demonstrate efficacy in both the supine and upright positions, suggesting the potential of MMS technology to significantly improve post-surgical patient care. To compare the analgesic effect of single doses of etoricoxib 120 mg, oxycodone/ acetaminophen 10 mg/650 mg and codeine/ acetaminophen 60 mg/600 mg in acute pain using the dental impaction model. To determine if this effect was longer-lasting (because of the possible role of the pineal in bowel malignancy) the crypt cell proliferation rate was determined in rat small bowel and colon 6 months after pinealectomy, using a stathmokinetic technique.
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The aim of the present study was to determine the rate of neoplastic seeding after RFA in a large series of unselected patients with HCC who had a long follow-up. Monoolein and oleic acid did not enhance the topical and transdermal delivery of TAT or YARA but increased the topical delivery of YKAc. On a method of calculating the true cervico-diaphyseal angle of the femur. Bronchological treatment of chronic nonspecific lung diseases with bronchospastic syndrome. Cloning, expression and purification of a recombinant poly-histidine-linked HIV-1 protease. Lymphocyte subpopulations including CD2, CD3, CD4, CD8, CD19, CD20, and CD25 were also measured, rhG-CSF was administered once daily as a 30-min infusion. In F344 but not in BDE rats, an additional indirect mechanism involving 5-HT release and mast-cell activation participates in the neurogenic PPE. The new 4-quinolones DU-6859a and DV-7751a show enhanced activity against Streptococcus pneumoniae.