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Conducil (Nifedipine)
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Conducil

Conducil is used to treat high blood pressure or angina (chest pain). For high blood pressure: Conducil works by relaxing and expanding the blood vessels. This makes the blood flow more easily and lowers blood pressure. Lower blood pressure reduces the strain on your heart. For angina: Conducil works by relaxing and expanding the arteries supplying the heart. This allows more blood and oxygen to reach the heart and decreases the strain on it. Your angina attacks will be less severe and less frequent if there is less strain on the heart.

Other names for this medication:
Addos, Afeditab, Antrolin, Aprical, Atanaal, Calchan, Calcigard, Cardifen, Cardules, Chronadalate, Cobalat, Cordaflex, Cordalat, Corinfar, Duranifin, Emaberin, Fedip, Herlat, Hypan, Menoprizin, Nedipin, Nidipine, Nifangin, Nifecard, Nifedate, Nifedical, Nifedipina, Nifelong, Nifensar, Nifeslow, Nifestad, Niften, Nipidin, Nipress, Sidalat, Tenif, Tredalat, Valni, Viscard, Xepalat

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Azulfidine, Zudena, Avodart, Celebrex, Aygestin, Nuvigil, Glyburide, Temovate

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Also known as: Nifedipine

Description

Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Adalat OROS. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Conducil and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nifedipine dosage information

Side effects

The most common side effects associated with Conducil are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies have not been performed on the relationship of age to the effects of nifedipine in the pediatric population. Safety and efficacy have not been established.

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Immunohistochemical study identified enhanced caspase-3 expression in the cytoplasm and nuclei of airway and alveolar epithelial cells and vascular endothelial cells in rats with high VT ventilation, and the enhancement was especially obvious in the bronchial epithelial cells. We describe a method for generating a plasmid library expressing random truncations of a recombinant protein and for epitope mapping by screening the library with monoclonal antibodies. Boys had an increased risk for ADHD compared with girls, but only among siblings from antisocial families. It was concluded that norepinephrine exerted a favourable effect on right ventricular function. As shown previously, transforming growth factor (TGF)-alpha stimulated proliferation of type II cells in vitro. Relationship of components of papilloma virus to papilloma and carcinoma cells. The cylindrical organ can be broken down into three longitudinal regions arranged in an apical-basal order: stigma, style, and ovary. These findings support the hypothesis that after removal of trophic support, post-mitotic neuronal cells die due to an attempt to re-enter the cell cycle in an uncoordinated and inappropriate manner. GAP was readily phosphorylated on tyrosine by WT but not K269E Hck. DNA-dependent DNA polymerase induced by herpes virus papio (HVP) in producing cells.

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Determination of protein catabolic rate in patients on chronic intermittent hemodialysis: urea output measurements compared with dietary protein intake and with calculation of urea generation rate. Overexpression of 14-3-3sigma in both NPC cell lines reduced the tumor volume in nude mice, which could have significance for clinical application. It is unclear whether this unusually good articulation is linked to the ability of such persons to process speech signals containing energy that falls within the range of their residual, high-frequency hearing (for example, certain consonants). Overexpression of a surface-membrane permeability glycoprotein (Pgp) was identified in ovarian cancer of patients who had clinical multidrug resistance in 1985. Maximal temperature reduction by ipsapirone was significantly blunted in older subjects and was inversely related to age.

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Evaluation of susceptibility in macrophage and animal models is helpful because drugs concentrated in cells may be more efficacious against MAC--an intracellular pathogen--than would be predicted by results in cell-free systems. A diagnostic and prognostic tool for epidemiologic and economic analyses of dairy herd health management. Biliary sludge: necessity for a better distinction between crushable and noncrushable microconcrements. Such an involvement has been established in several animal models and in hypertensive patients. To describe and evaluate an application of sonography, transorbital color Doppler flow imaging of the carotid siphon and major intracranial arteries, and to compare it with transtemporal color Doppler flow imaging.

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The barrel-stave model as applied to alamethicin and its analogs reevaluated. An immunoconjugate, CD5 Plus, composed of ricin A chain and murine IgG1 anti-CD5 monoclonal antibody is under investigation for treatment of rheumatoid arthritis. Only type 4 photosensitivity (photoparoxysmal response, PPR) was considered in the study. After growth hormone treatment, expression levels of insulin-like growth factors-I and II, and growth hormone receptor were determined in the bone regenerate of the original defects. The role of endothelin-1 in regulating human granulosa cell proliferation and steroidogenesis in vitro. Moreover, the maintenance of this form of synaptic plasticity does not seem to require a sustained change in transmitter release.

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Crystalline eye degeneration as the 1st sign of plasmocytic myeloma. Liver and eye have previously been shown to be effective matrices for the detection of residual concentrations of the drug. Using a microinjection technique, we report here that HBx efficiently blocks p53-mediated apoptosis and describe the results of studies exploring two possible mechanisms of HBx action. Overexpression of myotonic dystrophy kinase in BC3H1 cells induces the skeletal muscle phenotype. This type of combined procedure offers both the benefits of extra capsular surgery: avoids neovascular glaucoma in diabetic patients, keeps silicone oil in good position, possible implantation in the capsular bag, and those of a small incision: absence of leakage, of myosis, of corneal clouding, rapid rehabilitation. Alloimmunization to Gm markers is common in rheumatoid arthritis, an allegedly autoimmune disease. Finally, molecular blockade of NF-kappaB (Ad5IkappaBAA) or p38MAPK (Ad5dnp38) signaling strongly inhibited enterocyte restitution. The re-endothelialization was followed by a return to normal fibrinolytic activity.

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Visual acuity deteriorates as a result of nystagmus, glaucoma, cataract, corneal opacities and retinal hypoplasia. Stereoscopic macroradiography was used to study the pattern of union of scaphoid fractures. The causal enzymatic defect, the virtual absence of fructose-1-phosphate aldolase, occurs in the kidney as well as in the liver of patients with HFI. Differential distribution of CaM kinases and induction of c-fos expression by flashing and sustained light in rat retinal cells. All virus polypeptide profiles consisted of 7--10 polypeptides of which two were glycosylated. It was hypothesized that percutaneous instillation of fibrin sealant is effective for the postoperative treatment of refractory donor-site seromas. Assessment of cerebrovascular risk profiles in healthy persons: definition of research goals and the Austrian Stroke Prevention Study (ASPS).

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Issues of the restoration treatment optimization of patients with locally spread extracerebral tumors (LSET) were discerned basing on analysis of 54 observations. The small reversible movements of the mammalian type I vestibular hair cells are discussed in terms of mechanical adaptation processes and morphological features. The aim of the current study was to investigate the effect of pre-treatment with SOD on the chemical mediators in hyperoxic lung injury. This paper deals with the organization, the data processing and some of the results obtained in Italian external quality assessment (EQA) schemes for hormones, tumor markers and hepatitis B markers. In a study of cervical injury in New Zealand rugby football in the years 1973 to 1978 inclusive, 54 cases of injury were identified of which five were fatal. Reaction mechanisms of the ultrafast photoisomerization between cyclohexadiene and hexatriene have been elucidated by the quantum dynamics on the ab initio potential energy surfaces calculated by multireference configuration interaction method.

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Enzymatic conversion of 32-oxygenated delta-7-lanosterol derivatives and of delta-8(14)-4,4-dimethyl-cholestenol to cholesterol. A computer program framework was established to enable a dairy herd production consultant to perform whole-herd analysis. However, this effect was not antagonised by p-aminobenzoate or folic acid. Short-term juvenile crowding arrests the developmental formation of dendritic spines on tectal interneurons in jewel fish. They were dominated by the representatives of the genera Penicillium, Paecilomyces, Trichoderma, and Rhizopus. Despite these deleterious effects of sleep deprivation, even on healthy subjects, intensive care patients are rarely permitted sufficient natural sleep. Human serum low-density lipoprotein protein: its conformation studied by circular dichroism. The accumulation of mesangial matrix is a common histologic abnormality observed over the course of various glomerular disease. Clinical trial of ethynodiol diacetate in a sequential oral contraceptive. As a model system for this study, we analyzed a chromatin-enriched fraction from the yeast Saccharomyces cerevisiae.

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The existence of immunolabeled neuropile in the zebrafish retinorecipient strata could be related to the turnover of retinotectal projections. The implications of this study are that monitoring of self-concept throughout the transitional period for new nurses can lead to early detection and appropriate intervention strategies thereby improving retention rates for new nurses. Novelty of the pyruvate metabolic enzyme dihydrolipoamide dehydrogenase in spermatozoa: correlation of its localization, tyrosine phosphorylation, and activity during sperm capacitation. Three-year outcome of family work in an early psychosis program. J chain and HNP-1 cDNA were amplified from the plasmids pCH-J and pBabeNeo-HNP-1 respectively, then the J-HNP-1 DNA fragment was obtained by recombinant polymerase chain reaction (PCR). These results also have implications for cardiac excitability under conditions, such as ischemia, where membranes are depolarized. We describe three novel human Anp32 proteins, reveal the evolutionary relationships of the members of the Anp32 family, provide insights into their biochemical and structural properties, and review their macromolecular interactions, substrate specificities, tissue distribution/expression patterns, and physiological and pathological roles. This article offers practical advice on which topic to select and on how to develop and implement guidelines.

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Atropine is no better than placebo in the treatment of biliary tract pain. Gestation day (GD) 12 mouse embryos and HEPM cells were used to test the hypothesis that the cell-cycle block induced by SAD results from a disruption of stage-specific regulatory components both in vivo and in vitro. The packing of the layers, however, is different for the two polymorphs. Vascular responses to smoking tobacco compared with responses to skin testing of tobacco extracts. CTP assessment of ROI surrounding an oxygen probe in the intraparenchymal brain tissue is feasible and showed a significant correlation between P(br)O(2) and MTT. In addition, this model can be useful for the development of meaningful therapeutic animal models. For purposes of comparison, another lesion was placed in area V1 in one animal. These studies demonstrate efficacy in both the supine and upright positions, suggesting the potential of MMS technology to significantly improve post-surgical patient care. To compare the analgesic effect of single doses of etoricoxib 120 mg, oxycodone/ acetaminophen 10 mg/650 mg and codeine/ acetaminophen 60 mg/600 mg in acute pain using the dental impaction model. To determine if this effect was longer-lasting (because of the possible role of the pineal in bowel malignancy) the crypt cell proliferation rate was determined in rat small bowel and colon 6 months after pinealectomy, using a stathmokinetic technique.

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The aim of the present study was to determine the rate of neoplastic seeding after RFA in a large series of unselected patients with HCC who had a long follow-up. Monoolein and oleic acid did not enhance the topical and transdermal delivery of TAT or YARA but increased the topical delivery of YKAc. On a method of calculating the true cervico-diaphyseal angle of the femur. Bronchological treatment of chronic nonspecific lung diseases with bronchospastic syndrome. Cloning, expression and purification of a recombinant poly-histidine-linked HIV-1 protease. Lymphocyte subpopulations including CD2, CD3, CD4, CD8, CD19, CD20, and CD25 were also measured, rhG-CSF was administered once daily as a 30-min infusion. In F344 but not in BDE rats, an additional indirect mechanism involving 5-HT release and mast-cell activation participates in the neurogenic PPE. The new 4-quinolones DU-6859a and DV-7751a show enhanced activity against Streptococcus pneumoniae.

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The peripheral blood transcriptome dynamically reflects system wide biology: a potential diagnostic tool. Reactivation of the initial retinal condition presumably results from the rupture of quiescent parasitic cysts lying adjacent to pre-existing scars and may secondarily involve the choroid (leading to retinochoroiditis). The effect of squint surgery on pupil size was investigated in 19 patients. Cytoskeleton reorganization mediates alpha6beta1 integrin-associated actions of laminin on proliferation and survival, but not on steroidogenesis of ovine granulosa cells. A lower extremity venous duplex scan demonstrated isolated dilatation of the popliteal veins in both lower extremities. Curcumin can suppress the growth of LNCaP, and promotes their apoptosis. Two different MR techniques were used to guide the ultrasound beam.

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On the problem of the effect of interoceptive irritation on electrical activity of the cerebral cortex following the administration of aminazin. Comparison of data sets from the different species showed that most of the receptor subgroups that form the glutamate family are present in both mammalian and bony fish lineage. An intraocular lens was implanted using the recommended insertion system. Simple photografting method to chemically modify and micropattern the surface of SU-8 photoresist. There are barriers to doctors detecting depression in general practice. No plant materials have been investigated for its activity against B. We yielded network sub-graphs from these top ranking features representing formate fermentation, in good agreement with the anaerobic response of hetero-fermentative bacteria. Weak-acid transport in the small intestine: discrimination in the lamina propria. The underlying mechanisms leading to the association are not yet established, but it is possible that small dense LDL are per se atherogenic.

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A 68-year-old man who ingested an improperly prepared extract of pokeweed had sweating, confusion, tremor, weakness, incontinence, and syncope. The resulting HAT-sensitive hybrid cells were stained with the fluorescence marker tetramethyl rhodamine isothiocyanate (TRITC) and fused by polyethylene glycol (PEG) with HAT-non-sensitive unstained hybrid cells producing antibodies to horseradish peroxidase (POD). We conclude that, as far as diversity measurement is concerned, quadratic entropy is most relevant when applied to ultrametric dissimilarities. This anti-inflammatory effect is mediated by an interaction between acetylcholine, the principal neurotransmitter of the vagus nerve, and cholinergic nicotinic acetylcholine receptors on macrophages. The rat phospholipase C beta 4 gene is expressed at high abundance in cerebellar Purkinje cells. 6654 participants in 27 centres had lung function measured in 1991-93, when aged 20-44 years, and in 1998-2002.

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By six months of age, transgenic mice lost their ability to respond to training in a spatial learning water maze test, whereas they performed normally in this test at the age of four weeks. Instant evaluation of thyroid function using peripheral indicators in various glimepiride 1 mg tablet picture combinations. The characteristic features are failure to take phosphate-binding antacids on a regular basis, intractable congestive heart failure, atrioventricular block, a calcium phosphate product consistently greater than 60, and sudden irreversible cardia arrest. We describe a case where a further occlusion of the ipsilateral common carotid artery (CCA) resulted in an intermittent reversal of flow in the ipsilateral external carotid artery (ECA), to siphon blood up the internal carotid artery (ICA) and down the ipsilateral vertebral artery. Our results are of interest for the management of antiretroviral therapy in NRTI-experienced patients. 58 m/s), but the rise times were significantly prolonged (mean, 2.0 ms vs 1.2 ms). Disruptions of the external ear canals were confirmed at surgery, and the dogs each responded to total ear canal ablation and lateral bulla osteotomy. In this article the possible role of tyrosine phosphorylation is discussed. The fibronectin receptor, alpha 5 beta 1, has been shown to be required for fibronectin matrix assembly and plays an important role in cell migration on fibronectin.

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This study investigated whether neural mechanisms of self-face recognition are modulated by attention by recording event-related brain potentials associated with self-face recognition. Menthol has a selective potentiating action on cutaneous cold receptors and shifts the temperature response curve of the bladder cooling reflex towards higher temperatures in animal experiments. Current molecular genetic results indicate that the gene for the X linked form is located in the proximal Xq28 region. Medical research on child abuse has a short history of only 20 years. Among the VH CDR3 of these 10 antibodies, 4 displayed arginine residues as a result of N region additions. There is evidence that a common polymorphism in CYP17 (T27C) is associated with estrogen levels, making it a potential marker of disease risk.

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Mutants of Toxoplasma gondii resistant to atovaquone (566C80) or decoquinate. The lens as an osmometer and the effects of medium osmolarity on water transport, 86Rb efflux and 86Rb transport by the lens. Plasma lysozyme level and reticuloendothelial system function in human liver disease. Olfactory neuroepithelial (OE) cells were dissociated from late stage embryonic mice and analysed for carnosine expression. However, it seems that even more general entropies could be useful in order to describe other complex physical systems, a task which has already been undertaken in the literature. Significance of various factors in patients with functional dyspepsia and peptic ulcer disease in Greece. Our results show for the first time that Wolbachia is recognized specifically by D. The mechanisms by which lesions are produced are sometimes difficult to pinpoint but all are generally preventable. Autonomic reflexes in patients with cardioinhibitory carotid sinus syncope.

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Thin, frozen sections were labelled with antibodies against two resident Golgi markers, beta-(1,4)-galactosyltransferase and N-acetylglucosaminyltransferase I. Simultaneous measurement of pulmonary venous flow by intravascular catheter Doppler velocimetry and transesophageal Doppler echocardiography: relation to left atrial pressure and left atrial and left ventricular function. However, our study also suggests an indirect negative effect of acculturation on safety belt use through drinking and driving. Ethanol induced DNA single-strand breaks in repair deficient but not in repair proficient Saccharomyces cerevisiae. The prevalence of intestinal helminths in religious groups of a rural community near mometasone furoate topical solution brand name Calcutta. In addition, coexpression of NOS and vasoactive intestinal peptide (VIP) or calcitonin gene-related peptide (CGRP) was studied using a combination of histochemistry for NADPH-d and immunohistochemistry for VIP or CGRP. Hepatitis and pneumonia associated with ECHO virus, type 9, infection in two adult siblings.

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SDS-PAGE analyses revealed proteins of 29, 60 and 70 kDa for R and L. We also found that expression of genes involved in cell-cycle control, DNA repair, and lipid metabolism was suppressed by IFN-gamma. In normal bladder zithromax suspension dosing , the alpha 6 beta 4 integrin co-localized with collagen VII at the junction of the basolateral surface of the basal urothelial cells and the lamina propria. Low-dose cytosine arabinoside in patients with acute myeloid leukemia not eligible for standard chemotherapy. Long-time results and associations between subjective visual difficulties with car driving and objective visual function 5 years after cataract surgery. The method was rapid, reproducible, and accurate in comparison to thermoplaster casts.

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In a second experiment plasma cholecystokinin levels were measured before and during intravenous administration of bombesin in six patients with ileal pouch and five healthy volunteers. The number and area of AgNORs per nucleus were decreased significantly by dietary treatment with these four phenolics. Elevated levels of proinflammatory cytokines, including tumor necrosis factor-alpha, are found in skin lesions and plasma of patients with psoriasis. A significant difference in the proportion of large micronuclei between high and low doses was observed. The response to carbemazepine was dramatic, with complete cessation of the crisis and disappearance of the spontaneous activity in the electromyogram. Post-operative and complications of repair operations for prolapse. In Neurospora, transformation of spheroplasts is quite efficient and usually occurs with the transforming DNA integrated at ectopic sites in the chromosome.

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