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Clobezine (Clobetasol)

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Clobezine is an inexpensive steroid used on the skin to treat itching, redness, and swelling caused by some skin conditions. This drug is slightly more popular than comparable drugs. It is available in multiple generic and brand versions.

Other names for this medication:
Agiclob, Betalic, Clobate, Clobecos, Cloberis, Clobesym, Clobetamil, Clobetasol, Clobex, Clobezine, Clobin, Clomad, Clomic, Clonate, Cloriv, Clotof, Clovate, Cortaz, Covate, Cutivate, Cvate, Eavone, Ecziclo, Embeline, Etavone, Gracederm, Hinate, Isovate, Kloryl, Klosol, Lobate, Magclo, Miclogenta, Miconit, Salyco, Sonaderm, Steriderm, Steridom, Taxalic, Tenovate, Tigerderm, Topifort, Topisal, Zincoderm

Similar Products:
Vermox, Risperdal, Imovane, Sildigra, Detrol, Antivert, Nizoral, Eldepryl

Also known as: Clobetasol


Clobetasol topical is used to help relieve redness, itching, swelling, or other discomfort caused by certain skin conditions. The solution is used for scalp problems, the foam is used for mild to moderate plaque psoriasis, the cream, lotion, and spray are used for moderate to severe plaque psoriasis, and the foam and shampoo are used for moderate to severe scalp psoriasis. This medicine is a corticosteroid (cortisone-like medicine or steroid).

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain clobetasol. It may not be specific to Temovate E. Please read with care.

It is very important that you use this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause unwanted side effects or skin irritation.

This medicine comes with a patient information leaflet. Read and follow the instructions carefully. Ask your doctor if you have any questions.

This medicine is for use on the skin only. Do not get it into your eyes, nose, mouth, or vagina. Do not use it on skin areas that have cuts, scrapes, or burns. If it does get on these areas, rinse it off right away with water.

To help clear up your skin or scalp problem completely, it is very important that you keep using this medicine for the full time of treatment. Do not miss any doses.

This medicine should only be used for skin conditions that your doctor is treating. Check with your doctor first before using it for other conditions, especially if you think that a skin infection may be present. This medicine should not be used to treat certain kinds of skin infections or conditions, such as severe burns.

Do not use this medicine on the face, groin, or underarms, or if you have skin thinning, unless directed to do so by your doctor.

To use the cream, foam, gel, lotion, ointment, or spray:

Wash your hands with soap and water before and after using this medicine. Apply or spray a thin layer of this medicine to the affected area of the skin. Rub it in gently. With the lotion, protect the skin from water, clothing, or anything that causes rubbing until the medicine has dried. Also, shake the lotion well before using it. With the foam, do not dispense directly from the can into your hands, unless the hands are the affected area. Do not bandage or otherwise wrap the skin being treated unless directed to do so by your doctor. Do not use Clobex® spray or Impoyz™ cream for more than 2 weeks unless your doctor told you to.

To use the foam, scalp solution, or shampoo:

Wash your hands with soap and water before and after using this medicine. Apply a thin layer of this medicine to the affected area of the scalp. Rub it in gently. Do not cover the scalp (eg, shower cap, bathing cap) while it is being treated. With the shampoo, do not wet your hair before using it. And if the shampoo gets on any part of your body other than your scalp, rinse the area well with water. Do not use the shampoo for more than 4 weeks, and the foam and scalp solution for more than 2 weeks unless your doctor told you to.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For redness, itching, and swelling of the skin: For topical dosage forms (cream, gel, or ointment): Adults—Apply to the affected area of the skin 2 times per day. Children 12 to 17 years of age—Apply to the affected area of the skin 2 times per day. Children younger than 12 years of age—Use is not recommended. For topical dosage form (lotion): Adults—Apply to the affected area of the skin 2 times per day. Children—Use is not recommended. For plaque psoriasis: For topical dosage form (cream): Impoyz™: Adults—Apply to the affected area of the skin 2 times per day. Children—Use is not recommended. Temovate®: Adults and children older than 16 years of age—Apply to the affected area of the skin 2 times per day. Children younger than 16 years of age—Use is not recommended. For topical dosage form (foam): Adults—Apply to the affected area of the skin 2 times per day, once in the morning and once at night. Children 12 to 17 years of age—Apply to the affected area of the skin 2 times per day, once in the morning and once at night. Children younger than 12 years of age—Use is not recommended. For topical dosage form (spray): Adults—Spray directly to the affected area of the skin 2 times per day. Children—Use is not recommended. For scalp problems: For topical dosage forms (foam or scalp solution): Adults—Apply to the affected area of the scalp 2 times per day, once in the morning and once at night. Children 12 to 17 years of age—Apply to the affected area of the scalp 2 times per day, once in the morning and once at night. Children younger than 12 years of age—Use is not recommended. For topical dosage form (shampoo): Adults—Apply to the affected area of the scalp once a day. Children—Use is not recommended.


Generic Clobezine is not expected to cause overdose symptoms. But long-term use of high Generic Clobezine doses can lead to symptoms such as: thinning skin, easy bruising, changes in the shape or location of body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Clobezine are:

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Development of one-tube multiplex polymerase chain reaction (PCR) for detecting Mycobacterium bovis. This localized type of infection was successfully treated with oral cotrimoxazole. Presently available studies have demonstrated, however, that beta blockers are well tolerated in the setting of an acute infarction as long as none of the usual contraindications are present. Mivacurium is a muscle relaxant with a short duration of action. Local muscle blood flow and sustained contractions of human arm and back muscles. The biopsy from the superior mucous membrane of the rectum disclose an inflammatory chronic granulomatous process. This study tests a hypothesis that high-risk human papillomavirus (HR-HPV) infection may correlate with proinflammatory Stat3 signaling activities and IL-17 levels in breast cancer (BC) patients. pneumoniae in 60-week-old mice did not differ from that in 4-week-old mice. Structural and evolutionary implications of the packaging of DNA for differentiation and proliferation in the lymphocyte.

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Inhibition of human bone marrow lymphoid progenitor colonies by antibodies to VLA integrins. In addition, expression of the c-src gene product increases when bone marrow cells are induced to express an osteoclast-like phenotype by 1,25-dihydroxy-vitamin D3, further suggesting that high expression of pp60c-src is part of the osteoclast phenotype. Effects of levorphanol and several kappa-selective opioids on respiration and behavior in rhesus monkeys. Alanine was by far the strictest requirement, because no residue could fully substitute for it in the case of HIF-P4H-1, and only serine or isoleucine, valine, and serine did this in the cases of HIF-P4Hs 2 and 3. Fixture placement posterior to the mental foramen with transpositioning of the inferior alveolar nerve. Separate mediation analyses indicated that metacognition mediated the relationship between executive functioning and self-regulated learning as well as between specific executive functions and self-regulated learning. In both M-F and F-M, height was a strong predictor of muscle mass. The national impact of alcohol and drug problems and HIV infection and AIDS among the poor and underserved.

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Combination therapy of theophylline tetracycline antibiotics bid and terbutaline as sustained-release preparations in patients with asthmatic bronchitis. Although non-toxic, our data do not justify the widespread use of low-dose oral nHuIFN alpha in HIV-infected patients outside controlled clinical trials. The records of 58 patients were considered, and all were available for analysis and follow-up. These results indicate that the encephalitogenic peptide can induce anergy in T cells when presented on class II MHC in the absence of the costimulatory signal. Yet our understanding of the inter-relationship between brain and mind remains hampered by the lack of a theoretical language for expressing cognitive functions in neural terms.

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Electrophysiological basis of the reinforcing effects of cocaine. Laparoscopic bipolar coagulation of uterine vessels: a new method for treating symptomatic fibroids. These results suggest that blood pressure should be monitored for at least 10 min after patients receive and intravenous NAPA injection, and that repeated NAPA doses probably should not be administered more frequently. This report reflects the interest of the Section of Hemodynamics and Interventional Cardiology of the Spanish Society of Cardiology in increasing quality, safety and applicability of percutaneous procedures, by giving scientific keys aimed at improving related functions of teaching or planning in this field and enhancing competence and prestige of Spanish interventional cardiologists. Spatial dissipative structures formed by spontaneous molecular aggregation at interfaces. At basal conditions and following exposure to UVA light alone, no changes in the normal platelet aggregation patterns were observed. However, many technologies that should reduce medical errors have been abandoned because of problems with their design, their impact on workflow, and general dissatisfaction with them by end users. Targeting apoptosis and DNA synthesis: understanding treatment concepts and nursing considerations.

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