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Evodiamine inhibited PKC activity, down-regulated the expression of ERK, phospho-ERK and Bcl-2, and staurosporine was capable of augmenting these effects induced by evodiamine. The effect of various antiinflammatory agents on the spontaneous cytotoxicity of human mononuclear cells in vitro was assessed. Together, these results suggest that the restricted regional pattern of cocaine-induced c-fos expression is related, in part, to the basal level of dynorphin expression, and that cocaine treatment elevates dynorphin expression in striatal regions with a strong c-fos response, thereby limiting subsequent c-fos induction by cocaine. These results demonstrate, in vivo, the functional involvement of VLA-4 on melanoma cells in IL-1-mediated lung colony augmentation, most probably involving the interaction of tumor cells with VCAM-1 on activated endothelial cells. MRI is extremely effective at detecting and characterizing focal hepatic lesions. Thirteen patients with mild heart failure without LBBB served as a comparison group.
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The Q1 (A) strains of Salmonella typhimurium: induction phenomena. Northern hybridization revealed that the messenger RNA level for transforming growth factor-beta 2 and IGF-II in stromal cell was reduced by tail suspension. A dense band of small, round cells was stained in layer 2 of pyriform cortex. And in people without disorders, phenomena such as hypnosis, automatic writing, Ouija board spelling, water dowsing, facilitated communication, speaking in tongues, spirit possession, and trance channeling also illustrate anomalies of will--cases when actions occur without will or will occurs without action. A new method of deriving the vectorcardiogram from routine clinical electrocardiographic leads. In addition, elderly persons demonstrated a significantly lower distribution of vascular tissue and a significantly higher presence of dense connective tissue in the central third of the posterior disc attachment. The essential components of psychiatric rehabilitation technology clearly are defined practitioner skills and the underlying knowledge about how to use the skills most effectively.
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burneti in wild animals in a natural focus of Q-fever and under experimental conditions. During shotgun cloning of an amylase gene, we found a transformant of Escherichia coli with a reddish color. Abdominal aortic aneurysms: preliminary technical and clinical results with transfemoral placement of endovascular self-expanding stent-grafts. Pulmonary angiography showed severe pulmonary artery anastomotic stenosis. Coronary vasomotion is influenced by a variety of factors, including atherosclerosis and diurnal variations in alpha-adrenergic tone. We report the presence of a candidate EGF precursor-processing enzyme in the lactating mouse mammary gland. In benign adenomatous colon polyps, villous adenomas were more frequently stained than tubular adenomas.
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New techniques of imaging are needed to locate the target lesion. Thus, the monoclonal antibody (mAb) Lp-3 may be the first mAb to murine CD43 defined by primary target structure analysis. This is followed by two other transitions, corresponding to orthoradial and radial diffusion, for which both individual and collective excitations play a significant role. Measurements were also made on ears from which the stratum corneum had been removed by stripping with Sellotape. Effects of acetazolamide, chlorothiazide and chlormerodrin on inulin clearance, true endogenous creatinine, para-aminohippuric acid and urea.
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Individuals of both species also covered more area while foraging and spent less time in shelter when crowded than when at lower densities. Studies on the antigenic structure of this protein show it to have several highly conserved epitopes, confirming similar earlier conclusions from amino acid sequence analyses. Hybridization of restriction digests of this fragment to individual probes for Methylobacterium extorquens AM1 mxaA, K and L indicated that the relative mxa gene order in Methylobacter albus BG8 is A-K-L. Overexpression of wild-type rab7 protein allowed normal transport to late endosomes (mannose 6-phosphate receptor positive), while the rab7N125I mutant caused the VSV G protein to accumulate specifically in early (transferrin receptor positive) endosomes. The myoarchitecture of the tongue is believed to consist of a complex network of interwoven fibers, which function together to produce a near limitless array of functional deformations. Fingerprinting of DNA and RNA by arbitrarily primed polymerase chain reaction: applications in cancer research. Mutations throughout an Arabidopsis blue-light photoreceptor impair blue-light-responsive anthocyanin accumulation and inhibition of hypocotyl elongation. Vascular considerations and complications in cranial base surgery.
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Abdominal colposacropexy shows a particularly favorable result on prolapse-related complaints. It also gives predictive information and might be of value as a marker in adjuvant therapy. The examinations were performed on the application of the Polish epoxide resin Epidian 51 for anatomical technics. In the tectum opticum neurons, the inhibition restricting the excitation, seems to facilitate responses of separate groups of neurons related to analysis of direction--velocity parameters. In addition, the available data suggest that anticoagulation can be used safely and effectively in most of these patients. Cancer Trials comprises an on-line database of all randomized trials of cancer therapy, whether phase III or randomized phase II trials. A case of pulmonary solitary metastasis of renal cell carcinoma nine years after radical nephrectomy. Patients who had endoscopic and pathologic evidence of IBD were identified, and their pathology was reviewed.
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Inadequate generation of atrial natriuretic peptide (ANP) has been one of the mechanisms discussed as to possibly contribute to the development of hypertension. Medical grand rounds from the University of Alabama Medical Center. Conjugation of wide-host-range octopine-type Ti plasmids requires a tumor-released arginine derivative called octopine. Evidence is presented which indicates that fluorides are transmitted from vegetation to herbivores and on to carnivores along food chains. Based on the molecular composition of the human erythrocyte cytoplasm, the contribution of each of the components (proteins, metabolites, electrolytes) in the overall values of the cytoplasm viscosity has been estimated. This phenomenon implies that phagocytosis of Abeta coincides with production of phosphorylated tau in the same reactive astrocytes. Three protocols for RBC and total WBC counts were compared, as were different centrifugation times for PCV determination, and 2 methods for Hgb concentration.
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Cell damage for cells grown on microcarriers in suspension is a critical problem for scale-up of microcarrier reactors. Many children showed clinical manifestations and eggs in their faeces on day 1-26 after birth, and more cases occurred within 3 months of birth. While gsb is a segment-polarity gene and mainly expressed in the epidermis, gsbn is expressed in the central nervous system. All three were treated with bromocriptine (5 mg/d in 2 doses) after verification of normal baseline and protirelin-stimulation prolactin levels. The 27 kDa polypeptide could no longer interact with the oriC region, and therefore the cleavage-site is likely to reside within the N-terminal DNA-binding domain of the IciA protein. The acclimative value of these changes was investigated by assessing photosynthetic function in these plants when exposed to two spectrally distinct actinic lights. Although governmental healthcare reform initiatives have come to a stop in Washington, DC, the healthcare delivery system is, nevertheless, being transformed. Heart rate variability did not differ between the two groups, and no consistent trends in heart rate variability were observed before ventricular fibrillation occurred.
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The administration of SP, 15 nmol, was found to transform feeding induced by stimulation of LH into escape. Autopsy of animals at hourly and daily intervals demonstrated that treatment with allopurinol provided protection against the untoward pathophysiologic changes which attend this kind of experimental infarct. Responses of isolated uterine arteries to local anesthetic agents. Study on the latest ramifications of arterial, venous and portal hepatotectonic in normal and pathological (cirrhotic) conditions: experimental research with the method of plastic reconstruction. Assess the pregnancies of our female renal transplant recipients and to document long term maternal and fetal outcome.
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In this assay (i) antigen specific lymphocyte priming activity of the three monoclonal Ab-2 and (ii) the in vitro stimulating ability of these Ab-2 for gb-1 primed mouse lymphocytes were tested. Structure-activity relationship studies of chemical mutagens and carcinogens: mechanistic investigations and prediction approaches. Endocrine factors (including testosterone, follicle-stimulating hormone, and luteotropic hormone), PSA level, prostate volume, and Gleason score were measured in 134 patients with untreated, biopsy-verified PCa. We suggest that interactions between the amino- and carboxy-terminal zippers normally mask the NLS sequences of HSF2 and that these interactions are disrupted upon activation to expose the NLS sequences and allow transport of HSF2 to the nucleus. Its value may also correspond to those which have been induced with accute irradiation. For each subject in both groups a key respondent best acquainted with the subject was interviewed by clinicians using standardized schedules.
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By comparing this interaction pattern with that detected in vitro in a nonfunctional complex, we proposed that a distinct conformation rearrangement takes place when the enzyme complex changes from the nonfunctional state to the activated functional state. The cellular changes found in the dental papilla were considerably different from those found in inflammation, resolution and repair of fibrous connective tissue. Histopathological examination of the traumatized spinal cord showed malacic and degenerative lesions. A patient was brought to the Emergency Department in presumed status epilepticus. An algorithm for treating shield ulcers and/or plaques is presented based on the experience at this institution. The use of a limbal approach allows removal of an IOL from the retinal surface and secondary IOL implantation in the preferred site during the same surgical procedure. Immunolocalization and expression of insulin-like growth factor I (IGF-I) in the mammary gland during rat gestation and lactation.
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43 women with physiologically proceeding pregnancy have been examined during 1st, 2nd and 3d terms. Pretreatment of L-carnitine also reduced the grade of ventricular arrhythmias induced both by acute myocardial ischemia and by supplemented of excess FFA. Considerable intersubject variability was observed for both slight and moderate pain thresholds, more so on glabrous than on hairy skin sites. To analyse CXCR3 expression in primary cutaneous malignant melanomas and its comparison with clinicopathological and prognostic factors. Pharmacological evaluation of selected, orally active, peptidyl inhibitors of human neutrophil elastase. Infection-associated loss of the ability of spleen cells to secrete interleukin-2 on stimulation with concanavalin A suggested transient immunosuppression.