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Both of these protein tyrosine kinases are thought to function via their interaction with cell surface receptors. In mitochondria-enriched preparations of human skeletal muscle, the measurement of pyruvate dehydrogenase activity, as determined by conventional spectrophotometric assay of NADH accumulation, is underestimated due to the oxidizing activity of the contaminating lactate dehydrogenase. Sputum was examined in 12 patients older than 10 years, (4 consecutive samples). Chronic D-amphetamine in nucleus accumbens: lack of tolerance or reverse tolerance of locomotor activity. Owing to the strong linkage of the immobilized immunoglobulin with the PVA-carrier, immunoaffinity chromatography on this sorbent does not involve contamination of the preparations with rabbit globulin allergenic for man. Therapeutic effectiveness of trichomycin in experimental keratomycosis and immunological considerations. In the placenta, a composite enhancer confers specific expression.
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Agreement and contradictions in clinical and anatomopathological diagnoses. Ulcerative colitis disease activity indices offer good statistical power but small changes in these indices may not be clinically important. A high-performance liquid chromatographic method is described for the quantitation of fenoprofen, dl-2-(3-phenoxyphenyl)-propionic acid, in human plasma. P wave changes after open heart mitral commissurotomy for isolated mitral stenosis. Protective effects of nylidrin and isoproterenol against hemorrhagic shock. Squamous cell carcinoma antigen serum levels as prognostic parameter in patients with early stage vulvar cancer. Obesity is a common comorbid condition among patients undergoing coronary bypass surgery. Cytological changes in the anterior hypophysis of the mouse following chronic exposure to heat.
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Wild-type, but not mutant, murine or human p53 expression vectors reduced the activity of reporter constructs when co-transfected into HeLa or C33 cell lines. It has been discussed controversially whether errors of choice (e.g., pressing an incorrect response button in an Eriksen flanker task) and errors of commission (e.g., pressing a button when one is not supposed to in a Go/Nogo task) are related to different ERN/Ne mechanisms. 126 cases presenting to the Child Guidance Clinic and the Eating Disorder Clinic at the Institute of Mental Health between 1994 and 2002 were identified and studied retrospectively. Spontaneous reperfusion occurred early enough to allow functional recovery in the ischemic retina. While mutant H452Q is severely crippled in catalysis of the physiological reaction, the reverse reaction is affected in the E457Q mutant. Administration of unopposed postmenopausal estrogen therapy protects against coronary heart disease (CHD) in women. One week later he died of intracerebral hemorrhage and autopsy revealed fungal prosthetic valve endocarditis.
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The therapy, as a topical formulation, is in phase II clinical trials for the potential treatment of atopic dermatitis and severe dermatological disorders. Furthermore, a repressive pattern of histone modifications was formed around the differentially methylated region in undifferentiated trophoblast stem cells with repressed Ddah2. Recombinant methionyl granulocyte colony-stimulating factor (filgrastim): a new dimension in immunotherapy. Axonal elongation of grafted, embryonic inferior olivary neurons in the adult rat cerebellum and their synaptic formation on host Purkinje cells. There is little agreement about which characteristics distinguish one type of plan from another. The selection of K65R was closely linked to the absence of TAMs at baseline and to the regimens sparing both protease inhibitors (PIs) and non-NRTIs.
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Effect of rhIL-2 in inhalant form on experimental respiratory tract infection with Klebsiella pneumoniae in mice. Fenoldopam mesylate is a selective dopamine-1 agonist, with no effect on dopamine-2 and alpha1 receptors, producing a selective renal vasodilation. Morphogenesis of the hereditary microphthalmia in a new strain of rat. At the postoperative visit to the GP a full discharge summary including histology was available for 88 patients. Aflatoxin B1 showed relatively high mutagenic activity in Ames test when incubated with human placental microsomes. When only few sequences are available for model fitting, additional prior information must be incorporated into the models.
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Morphologic manifestations of immune responses in disrupted tubal pregnancy. Grammatical features of fluent aphasic speakers have not received as much attention as those exhibited by non-fluent aphasic speakers. Osteoporosis, a metabolic disease, and periodontal disease, which is infectious, are both major health problems with multifactorial etiologies. A retrospective chart review was designed to evaluate urinary ketone levels, height and weight z scores and percentiles, and seizure reduction. Psychosocial determinants of late prenatal care: the Health Belief Model. Clinical contribution to the study of hydatid cysts of the hepatic cupola with thoracic evolution. We conclude that a high proportion of activated astrocytes and a small proportion of invading macrophages are induced to express moderate to high levels of nitric oxide synthase following neuronal damage. Evidence for an HIV-1-associated superantigen (SAg) has been presented. Discrimination of speed distributions: sensitivity to statistical properties.
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Diagnostic significance of ventricular premature beats in acute myocardial infarction. Inhibitory effect of TCV-309, a novel platelet activating factor (PAF) antagonist, on endotoxin-induced disseminated intravascular coagulation in rats: possible role of PAF in tissue factor generation. This report is a detailed biological characterization of bevacizumab in a variety of in vitro models. Transforming growth factor-beta 2 (TGF-beta 2), which is contained in the decidua and is thought to serve as a major immunosuppressive factor, reduced the NK activity of decidual CD16- CD56bright NK cells, but it hardly affected the IL-2-induced augmentation of the NK activity or DNA synthesis of decidual CD16- CD56bright NK cells. Each anesthetic is considered to bind to a site on the protein (perhaps, but not necessarily within the pore of the channel) and interrupt the flow of ions through the pore.
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Avidin was able to react with biotin when incorporated at position 106, not at 8, 179, or 286. To compare differences in coronary heart disease (CHD) risk factor levels between educational groups in the 1970s and 1980s in eastern Finland. Skeletal muscle consists of parallel bundles of myotubes formed by the fusion of myoblasts. Bactrocera dorsalis is the only representative of Group I, which is characterized by the typical metacentric X chromosome and major blocks of centromeric heterochromatin in autosomes 5 and 6. Epidemiology of leptospirosis in California: a cause of aseptic meningitis. With the recent availability of volumetric multiple exposure holograms, produced from serial image data, it is now possible to produce true 3D images of the pelvis. The levonorgestrel intrauterine system, which delivers 20 mug levonorgestrel per day, is now licensed for use as the progestogen component of continuous combined hormone replacement therapy. The radioprotective effect of IL-2 is dose dependent, does not result from the induction of cell proliferation, and does not require expression of the IL-2 receptor alpha chain.
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nov., a novel actinobacterium isolated from soil of a sugar-cane field in India. This report describes a 62-year-old woman with a history of pulmonary embolism who presented with a right ventricular cardiac mass that proved histologically to be normal thyroid tissue. N-Alkylglycine oligomers (peptoids) constitute a family of non-natural peptidomimetics attractive for the early drug discovery process because of their physicochemical features, easy of adaptation to combinatorial chemistry approaches and their proteolytic stability. Deletion mapping and sequence transfer studies have localized the determinant recognized by the Yae antibody to the region 195-208 of Pan-2. Several technical issues regarding DNA microarray are highlighted because of the rapidly increased use of this technology. A need for standardised schizophrenia pharmacoeconomic models exists. We suggest that production of NO by glomerular mesangial cells could occur, even when macrophage infiltration is not present, and could, thereby, modulate glomerular and tubular functions within the kidney. Much additional work is needed to better understand the precise mechanisms of G-CSF-induced neuroprotection. A significant tumoricidal effect was confirmed when the cells were grown and tested in conventional monolayer phase.
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Pharmacokinetic and pharmacodynamic study of amodiaquine and its two metabolites after a single oral dose in human volunteers. Treatment of pupillary block caused by aqueous pooling in vitreous. Strategies to provide career opportunities for health-care professionals in rural areas are always a challenge. The clinical evaluation of three-dimensional time-of-flight MR angiography was prospectively performed in 16 patients with intracranial meningioma. Overall, these findings provide additional evidence that the locomotor stimulant and rewarding effects of systemically administered psychomotor stimulant drugs are segregated within the ventral striatum. In conclusion, forensic age estimates of living subjects would be more powerful tools if population-specific standards were applied to evaluations of wisdom tooth mineralization. Equilibrium binding experiments showed that the formation of protein-probe complexes at increasing concentrations of protein had a sigmoidal shape for binding to RS sequences and a hyperbolic shape for binding to IR sequences.
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Late generalized tuberculosis--ie, disseminated tuberculosis occurring long after the primary infection-- is an often unrecognized cause of severe illness in patients with relative immunocompromise, such as the elderly, alcoholics, or those with chronic illnesses. N-9F cells and immature thymocytes proliferated in the presence of N-9F at 10(-12)-10(-9)M in a dose-dependent manner, but adult thymocytes were not stimulated by NPF. Quality of life is a major goal in the care of patients with terminal cancer. Carnitine depletion in rat pups of lactating mothers given sodium pivalate. To accurately determine chromosome loss, we advocate the use of single-copy probes in addition to, or in place of, pericentromeric probes. A complementary DNA encoding an ethylene-inducible acidic chitinase of azuki bean (Vigna angularis) was isolated, and its complete nucleotide sequence was determined. Since the clinical symptoms of pyomyositis are often insidious and delayed, an integrated imaging approach may be very useful for diagnosing this condition. A prospective study of laparoscopic radical nephrectomy for T1 tumors--is transperitoneal, retroperitoneal or hand assisted the best approach?.
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Value of monoclonal antibodies (PC 10, MIB1, p53 and LeuM 1) for assessing the prognosis of patients with squamous epithelial carcinoma of the larynx after partial laser resection. An outbreak of Campylobacter jejuni enteritis in a school of Madrid, Spain. In some cases, contrast-enhanced MR images may increase diagnostic confidence by showing homogeneous hypervascularization in bone marrow edema lesions and by depicting hypovascular marrow areas in AVN lesions. Chromocystoscopy could be used for monitoring cervical cancer patients. Evidence for an altered luteinizing hormone sensitivity to naloxone in pathological hyperprolactinaemia. Quantitation of myocardial iodine-123 MIBG uptake in SPET studies: a new approach using the left ventricular cavity and a blood sample as a reference. Effect of whole-body gamma irradiation on lipid peroxidation in rat tissues. Eyeblink conditioning deficits indicate timing and cerebellar abnormalities in schizophrenia. The allotetraploid nature of the crop was confirmed and molecular markers that can possibly identify the other genomic donor were proposed.