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Capres (Capecitabine)
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Capres

Capres is a chemotherapy drug. It treats certain types of cancer like breast cancer, colon cancer, and rectal cancer. Capres belongs to the group of medicines called antineoplastics (cancer medicines).

Other names for this medication:
Capecitabine, Capegard, Capehope, Capget, Capiibine, Capres, Capscare, Captabin, Capxcel, Distamine, Naprocap, Xabine, Xelocel

Similar Products:
Fulvicin, Flonase, Maxalt, Aristocort, Precose, Imdur, Coreg

Also known as: Capecitabine

Description

Xeloda (capecitabine) is a cancer medicine that interferes with the growth of cancer cells and slows their spread in the body.

Xeloda is used alone or in combination chemotherapy to treat colon cancer, breast cancer, or colorectal cancer.

Xeloda is sometimes used when cancer has spread to other parts of the body (metastatic).

Dosage

Usual Adult Dose of Xeloda for Colorectal Cancer:

MONOTHERAPY: For first line treatment of patients with metastatic colorectal carcinoma when treatment with fluoropyrimidine therapy alone is preferred: -RECOMMENDED DOSE: 1250 mg/m2 orally 2 times a day (morning and evening; equivalent to 2500 mg/m2 total daily dose) for 2 weeks followed by a 1 week rest period given as 3 week cycles ADJUVANT TREATMENT IN PATIENTS WITH DUKES' C COLON CANCER: -RECOMMENDED DOSE: 1250 mg/m2 orally 2 times a day (morning and evening; equivalent to 2500 mg/m2 total daily dose) for 2 weeks followed by a 1 week rest period given as 3 week cycles for a total of 8 cycles (24 weeks) Comments: -The tablets should be swallowed whole with water within 30 minutes after a meal. Use: Colorectal Cancer: -As monotherapy for adjuvant treatment in patients with Dukes' C colon cancer who have undergone complete resection of the primary tumor when treatment with fluoropyrimidine therapy alone is preferred; this drug was non-inferior to 5-fluorouracil and leucovorin (5-FU/LV) for disease-free survival (DFS); physicians should consider results of combination chemotherapy trials, which have shown improvement in DFS and OS, when prescribing this drug as a single-agent in the adjuvant treatment of Dukes' C colon cancer -As first-line treatment of patients with metastatic colorectal carcinoma when treatment with fluoropyrimidine therapy alone is preferred; combination chemotherapy has shown a survival benefit compared to 5-FU/LV alone; survival benefit over 5-FU/LV has not been demonstrated with this drug as monotherapy; use of this drug instead of 5-FU/LV in combinations has not been adequately studied to assure safety or preservation of the survival advantage

Usual Adult Dose of Xeloda for Breast Cancer:

MONOTHERAPY: -RECOMMENDED DOSE: 1250 mg/m2 orally 2 times a day (morning and evening; equivalent to 2500 mg/m2 total daily dose) for 2 weeks followed by a 1 week rest period combined with docetaxel 75 mg/m2 as a 1 hour IV infusion, every 3 weeks IN COMBINATION WITH DOCETAXEL: -RECOMMENDED DOSE: 1250 mg/m2 orally 2 times a day (morning and evening; equivalent to 2500 mg/m2 total daily dose) for 2 weeks followed by a 1 week rest period given as 3 week cycles Comments: -The manufacturer prescribing information for docetaxel should be consulted for premedication advice. -The tablets should be swallowed whole with water within 30 minutes after a meal. Use: Breast Cancer: -In combination with docetaxel for the treatment of patients with metastatic breast cancer after failure of prior anthracycline-containing chemotherapy -As monotherapy for the treatment of patients with metastatic breast cancer resistant to both paclitaxel and an anthracycline-containing chemotherapy regimen or resistant to paclitaxel and for whom further anthracycline therapy is not indicated (e.g., patients who have received cumulative doses of 400 mg/m2 of doxorubicin or doxorubicin equivalents); resistance is defined as progressive disease while on treatment, with or without an initial response, or relapse within 6 months of completing treatment with an anthracycline-containing adjuvant regimen

Detailed Xeloda dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Capres are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not take Xeloda if you are allergic to capecitabine or fluorouracil, or if you have:

severe kidney disease.

To make sure Xeloda is safe for you, tell your doctor if you have ever had:

a metabolic disorder called DPD (dihydropyrimidine dehydrogenase) deficiency; liver or kidney disease; heart problems; or if you use a blood thinner and you have routine "INR" or prothrombin time tests.

Capecitabine can harm an unborn baby if the mother or the father is using Xeloda .

If you are a woman, you may need a pregnancy test to make sure you are not pregnant. Use birth control while using Xeloda and for at least 6 months after your last dose. If you are a man, use birth control if your sex partner is able to get pregnant. Keep using birth control for at least 3 months after your last dose. Tell your doctor right away if a pregnancy occurs.

Pregnancy may be less likely to occur while the mother or the father is using this medicine. Both men and women should still use birth control to prevent pregnancy because the medicine can harm an unborn baby.

Do not breastfeed while using Xeloda, and for at least 2 weeks after your last dose.

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Distal myopathies: clinical and molecular diagnosis and classification. An airline captain with a presenting sign of some premature ventricular contractions. Resilience of perinatally HIV-infected youth in European countries is poorly studied. Caution should be exercised when comparing the results of surface texture studies of dental hard tissues and restorative materials using varying types of stylus attached to a surface profilometer. This study investigated the relationship between the donor-recipient age gradient (DRAG) and posttransplant outcomes after DDLT. It was suggested that the X-to-Y ratio difference could stem from the abnormalities in retinogeniculate terminal arbors that have been shown to follow early eye removal.(ABSTRACT TRUNCATED AT 400 WORDS). The method is useful for assaying on the order of tens to hundreds of genes in multiple samples. Circulating Chlamydia pneumoniae DNA as a predictor of coronary artery disease. Quisinostat was selected for clinical development as it showed prolonged pharmacodynamic effects in vivo and demonstrated improved single agent antitumoral efficacy compared to other analogs. RelB, with RelA activity, maintained the basal survival of CLL cells from BM.

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b-AP15 is a recently described inhibitor of the USP14/UCHL5 deubiquitinases (DUBs) of the 19S proteasome. Infrared Thermography Investigation of an Evaporating Water/Oil Meniscus in Confined Geometry. We found that HFD-fed mice showed obesity, hyperlipidemia, NASH, and significantly increased levels of serum Ang-(1-7). In all protozoa described here and elsewhere microvilli represent the dominant structure. The selenium/irradiated group was similar to the irradiated group with respect to the thickness and irregularity of the enamel organic matrix region in the evaluated birefringence, as the intercuspal dimensions of the molars.

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A novel polyrotaxane-based delivery system for scutellarin: preparation, characterization, and in vitro evaluation. In addition, the lowest creatinine level during follow-up was taken into account as the optimum level of renal function recovery. Average auditory brain-stem responses (ABRs) evoked by left and right ear stimulation of varying intensities were recorded from ipsilateral and contralateral scalp placements in human neonates. The interaction of 3-indoleacetic acid and eosin in light and in darkness. With respect to disease severity, addition of bortezomib to the multimodal immunosuppressive treatment regimen was associated with an acceptable safety profile. After investigating the environment, it was found that the source of the transmission was a home humidifier. FACS analysis using these mCD22.Rgs revealed that ligands for mCD22 are expressed on both B and T cell lines and also normal B and T cells. Furthermore, TA regimen did not cause signs of internal-bleeding or damage to vital tissues in mice. The aim of this study was to evaluate the renal effects of NAC using neutrophil gelatinase-associated lipocalin (NGAL) blood levels in elderly patients undergoing coronary artery bypass grafting (CABG). Live oak (Quercus virginiana Mill.) trees are hosts to a complex of gall making arthropods.

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Effects of rocuronium pretreatment on muscle enzyme levels following succinylcholine. Human TAFII250 interacts with RAP74: implications for RNA polymerase II initiation. Disorders of creatine metabolism in patients with bronchial asthma. We conclude that machine learning has a useful place in molecular biology as a pattern discovery tool. Donor management remains one of the most neglected areas of transplantation. The aim of this study was to assess the prevalence, risk factors and spatial distribution of taeniasis in a rural area of the Democratic Republic of Congo (DRC), in the prospect of upcoming control activities. Activation of T cells recognizing an epitope of heat-shock protein 70 can protect against rat adjuvant arthritis. Chemically Driven Enhancement of Oxygen Reduction Electrocatalysis in Supported Perovskite Oxides. The evaluation tool of the clinical pharmacology unit has an acceptable construct validity and satisfactory reliability and validity. Aggressive antibiotic treatment, removal of the prosthesis, and flap advancement is advocated.

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Multiple organ metastases from ameloblastoma detected by FDG PET/CT imaging. A study of the correlation of antigen phagocytosis and the splenic histologic reaction with antibody formation in protein-depleted rats. Fluocinolone acetonide (FA) is commonly used as a steroidal anti-inflammatory drug. The effect of pH and time course of fibril formation was studied by light scattering spectroscopy. Importantly, 2 weeks after B treatment was started, increased cardiac VEGF expression and Akt and endothelial NO synthase activation were observed by comparing B-treated with drug-untreated failing hearts. We conclude that DTI measures in these tracts show relative stability, and that alternative explanations for the recent failures of replication must be considered. We have identified a novel immune semaphorin induced in human and murine B-cells under Th2 conditions. After purification and assessment of those active compounds from A. We propose a method for shortcut to adiabatic control of soliton matter waves in harmonic traps.

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