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Calsure (Calcitriol)
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Calsure

Calsure is in a class of medications called vitamin D analogs. It works by helping the body to use more of the calcium found in foods or supplements and regulating the body's production of parathyroid hormone. Calsure comes as a capsule and a solution (liquid) to take by mouth.

Other names for this medication:
Actical, Alfacal, Alfacip, Alfarich, Alphadol, Arachitol, Arcium, Aristrol, Biocal, Biocitral, Bonetuf, Calbovic, Calcibest, Calcimet, Calcitriol, Caldikind, Calgel, Calosto, Caltive, Caltop, Citroj, Denscal, Devita, Dmcal, Estovon, Ikmag, Koncal, Laretol, Novadee, Qpcal, Riecal, Rolsical, Septriol, Solbiocal, Statbone, Vezocal, Vitalpha, Zaxial

Similar Products:
Cardizem, Caverta, Cozaar, Nolvadex, Bactrim, Sovaldi, Motrin, Noroxin, Feldene, Estrace

Also known as: Calcitriol

Description

Generic Calsure is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Calsure are intestine and bone. Generic Calsure receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Calsure may also act on the kidney and the parathyroid glands. Generic Calsure is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Calsure has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Calsure, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Calsure in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Calsure produces other independent beneficial effects. Calsure is also known as Calcitriol. Generic Calsure treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Calsure is Calcitriol. Brand name of Generic Calsure is Calsure.

Dosage

Generic Calsure is available in capsules (0.25 mcg) and liquid form. Capsules must be swallowed whole. Do not crush or chew them. If you are prescribed the liquid form, use as directed. Follow dosing instructions closely. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. If you want to achieve most effective results do not stop taking Generic Calsure suddenly.

Overdose

If you overdose Generic Calsure and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Calsure are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Problems in children have not been reported with intake of normal daily recommended amounts. Some studies have shown that infants who are totally breast-fed, especially with dark-skinned mothers, and have little exposure to sunlight may be at risk of vitamin D deficiency. Your health care professional may prescribe a vitamin/mineral supplement that contains vitamin D. Some infants may be sensitive to even small amounts of alfacalcidol, calcifediol, calcitriol, dihydrotachysterol, or ergocalciferol. Also, children may show slowed growth when receiving large doses of alfacalcidol, calcifediol, calcitriol, dihydrotachysterol, or ergocalciferol for a long time.

Studies on doxercalciferol or paricalcitol have been done only in adult patients, and there is no specific information comparing the use of doxercalciferol or paricalcitol in children with use in other age groups.

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A previously undescribed projection to the prosubiculum and hippocampus has been found to originate from the prorhinal cortex which forms the medial wall of the rhinal sulcus along the lateral-most portion of the entorhinal cortex in the rhesus monkey. Its phosphorylation was stimulated in response to agents that activated either PKA or PKC. Stabilized patients maintained on fluphenazine decanoate did not show a significant change in performance during 3 months of treatment. To investigate the heterogeneity in antibody response to the various antigenic determinants of Candida albicans in patients with disseminated candidosis 201 serial serum samples from 45 patients with proven systemic candidosis were examined by immunoblotting (Western blotting) for antibodies to C albicans type A NCTC 3153. The purpose of this study was to determine masticatory and functional forces in three axes on mandibular implants supporting overdentures. The diagnosis of the limited thyroid-reserve syndrome is elucidated. A number of different mutations in the gene coding for the enzyme were found in humans causing the total or partial loss of its enzymatic function. The average time spent on scheduling, prepping, and doing the surgery was factored using employee rates. To investigate a new method of quantification of the diastolic notch of the flow velocity waveforms of uterine arteries in the prediction of hypertensive disorders of pregnancy.

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The development of snail control methods on an irrigated sugar-cane estate in northern Tanzania. To investigate the influence of nonworking-side interferences on mandibular masticatory movements and signs and symptoms of dysfunction of the masticatory system, an experimental balancing-side interference was introduced in 12 healthy subjects for 1 week. Mitochondrial granules in the normal and rachitic rat epiphysis. Vagal sensory innervation to baroreceptor regions of the cardiac outflow tract was completely absent, and the density of vestibular sensory innervation to the cristae organs was markedly decreased, compared to wild-type controls. Placental changes in perinatal death (functional-kyematopathological analysis for the initiation of preventive measures). Conversely activators of phospholipase A2 enhance the conversion. Epiregulin and amphiregulin are growth factors involved in cancer development, but their potential role in signaling in the gonads is still obscure.

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The effects of prazosin on adrenergic-stimulated fat-cell lipolysis and adenylate cyclase activity were investigated. Human JC virus is also known to produce a variety of tumors in newborn rodents, including retinoblastoma-like tumor. The goals of rehabilitation medicine programs are to promote health, restore functional impairments and improve quality of life. Antigenic Fingerprinting of Antibody Response in Humans following Exposure to Highly Pathogenic H7N7 Avian Influenza Virus: Evidence for Anti-PA-X Antibodies. Effects of intracerebroventricularly applied nicotine on enhanced gastric acid secretion and mucosal blood flow in rats. To determine whether different fractionation schemes could simulate low-dose-rate irradiation, ovarian cells of the carcinoma cell lines A2780s (radiosensitive) and A2780cp (radioresistant) and AG1522 normal human fibroblasts were irradiated in vitro using different fraction sizes and intervals between fractions with an overall average dose rate of 0.53 Gy/h. Early ossification in the skeleton of the sucker (Catostomus macrocheilus) and the guppy (Poecilia reticulata). Traffic accidents: an epidemiologic problem in the area of public health. It was concluded that a number of pituitary polypeptides have the potential to provoke androgen sulphate synthesis by the human fetal gland in early gestation. We have analysed the evolution of a series of clinical and socio-economic indicators comparing, in the patients admitted with diagnose of complicated diabetic foot, the previous period to the implantation of the clinical pathway years 1998, 1999 and 2000) with the later period to this implantation (years 2001 and 2002).

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Successful pregnancy in a patient with polycystic kidney disease and advanced renal failure without prophylactic dialysis. Nineteen specimens from primary human malignant mesotheliomas obtained from 19 patients were screened for activating point mutations in the oncogenes N-ras and CDK4 by combined RFLP-PCR/SSCP analysis. We found that the endogenous deficiency of IL-4 did not confer protection from early atherosclerosis in the IL-4T KO as compared to their WT littermates (determined at the aortic sinus). Our scoring system was an efficient clinical predictive tool to identify patients with bronchiectasis at risk of exacerbations. Cultured CHO cells were pre-exposed to either X-rays or mitomycin C and given different doses of the polycationic compound during G2 in order to analyze any effect on the frequency of chromatid-type aberrations as well as any modification of cell-cycle kinetics. The use of thrombolytic agents in myocardial infarction remains controversial. Experimental pellicles were formed by incubating these materials in fresh human parotid or submandibular-sublingual saliva for 2 hours. There have been some attempts to categorize behavioural responses to pain by people with an ID, however, they have not been developed into a useful assessment tool.

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Rationalization of the technic for construction of partial fixed prosthesis: preparation application in 2 sessions. Since the incidence of the histological subtypes of lung cancer in industrialised countries has changed dramatically over the last two decades, we reviewed trends in the incidence and prognosis in North America, Australia, New Zealand and Europe, according to period of diagnosis and birth cohort and summarized explanations for changes in mortality. Cytochrome oxidase histochemistry was used to examine the effect of visual deprivation on the development of the neuronal network in the optic lobe. This study showed that during the whole rapid reduction in blood pressure with SNP, MCA V(mean) decreases almost one on one with MAP. Identifying these targets and understanding how they are regulated will have a major impact on our understanding of the molecular basis of transformation. At the end of 6 years of storage at 2 to 4 C, the samples still contained 20 to 5,000 MLD of toxin per gram, with the usual toxin level at 200 to 500 MLD.

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Plasma renin activity in maternal and umbilical cord blood during parturition. Analysis of all three mutants indicates that they decreased the inhibition of transposition that the protein exerts (in trans) on another element. Mouse livers were stored in the University of Wisconsin solution for 24 h at 4 degrees C and reperfused for 1 h at 37 degrees C in vitro. A false aneurysm that developed at the nidus of the cerebellar AVM in a 5-year-old boy is reported. The rates of AE in the LEF group, alone and combined with MTX, were generally lower than or comparable to the AE rates seen with MTX and other agents. A stent was placed in the SMA stenosis to preserve intestinal blood flow in the SMA region after total pancreatectomy, which was performed 25 days after stent placement. miR-145-MNPF is an efficient system for miR-145 delivery and restitution in pancreas cancer that may offer a potential therapeutic treatment for PC either alone or in conjunction with conventional treatment.

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Labile blood serum globulins: the importance of their determination and the mechanisms of their change in pathology. Other cerebral ion channel genes remain candidate genes for AHC. The purpose of study was to measure the diagnostic utility of interocular retinal nerve fiber layer (RNFL) symmetry and interocular RNFL thickness comparison. The interacting domains of both proteins were mapped using yeast two-hybrid assays. Purification of an acid alpha-glucosidase by dextran-gel filtration. Studies of A, B or O (H) surface antigen specificity: carcinoma in situ fenofibrate maximum dose and non-malignant lesions of the bladder. Instead, ultrasound efficiency started even to decrease with input power at long distances from the transducer. The results have always yielded positive data even though with marked differences of a quantitative order from a case to another. Here, we review how adaptation in the laboratory by directed evolution can complement studies of natural enzymes in the effort to understand stability and function. Chronic respiratory disease and high altitude are associated with depressive symptoms in four diverse settings.

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Substrate-specific inactivation of staphylococcal penicillinase. This is the first known case of a patient with interstitial deletion of chromosome 10 with symptoms of ascites and hydrops. Some vaccines exert different effects: attenuated live measles vaccine induces interferon, pertussis vaccine activates lysosomal enzymes of macrophages. Proceedings: Antibiotic susceptibility of Streptococci isolated from blood. These may include modifying effects on plaque growth and wound healing. modification has been discussed from varius points of view, considering records of what has been observed in the present research and what reported in literature. this is a brief review about the impact of faith, spirituality, and religiosity, particularly the Spiritism philosophy as complementary treatment to neurological disorders (particularly focusing on epilepsy) and mental health. A study of the fluorometric method for phenylalanine in serum samples. Similarly, PDGF activation of S6K1 was significantly inhibited by transient transfection or stable transfection of the cells with a dominant-negative Rac1 (Rac1N17), while overexpression of constitutively active Rac1 (Rac1V12) in the cells led to an increase in basal activity of S6K1.

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Comparative Study of Improvement of Nasal Symptoms Following Septoplasty with Partial Inferior Turbinectomy Versus Septoplasty Alone in Adults by NOSE Scale: A Prospective Study. We studied the effect of tetracycline and penicillin on meningococcal and gonococcal pili. Two independent approaches were used to determine which of these three open reading frames encoded the protein. PKC epsilon-related kinase associates with and phosphorylates cytokeratin 8 and 18. The inward rotation of electron-donating sigma(CX) bonds and outward rotation of electron-withdrawing sigma(CX) bonds have been deduced from the orbital-phase theory. Engorgement of the spermatic vein proximal to the endoclip site was noted. Numbers of enhancing lesions correlated well with an increase of ventricular size. Therefore, subsequent patients were treated with dexamethasone, beginning the day of liposomal cytarabine administration and continuing for 5 days. Metabolism of 1-palmitoyl diolein and 3-palmitoyl diolein by adipose tissue. Use of the indirect fluorescent technique with anti-M sera absorbed with lyophilized nitrous acid extracts permits the possible differentiation of the two M-protein determinants in situ on the surface of streptococcal cells.

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