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Calcigra (Calcitriol)

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Calcigra is used to treat and prevent low levels of calcium and bone disease in patients whose kidneys or parathyroid glands are not working normally. It is also used to treat secondary hyperparathyroidism (a condition in which the body produces too much parathyroid hormone and metabolic bone disease in people with kidney disease.

Other names for this medication:
Admax, Alfacip, Alfarich, Apcical, Arachitol, Arcium, Aristrol, Calasto, Calbovic, Calcibest, Calcimet, Calcitriol, Caldikind, Caldix, Calfa, Caltive, Caltop, Calvical, Carcal, Denscal, Devita, Duracal, Estovon, Fovit, Ikmag, Kurecal, Netxod, Novadee, Qpcal, Rical, Riecal, Ritoca, Roical, Rolsical, Romical, Septriol, Sorvate, Sunmic, Vezocal, Zaxial

Similar Products:
Avelox, Kemadrin, Symmetrel, Fosamax, Imovane

Also known as: Calcitriol


Vitamins are compounds that you must have for growth and health. They are needed in small amounts only and are available in the foods that you eat. Vitamin D is necessary for strong bones and teeth.

Lack of vitamin D may lead to a condition called rickets, especially in children, in which bones and teeth are weak. In adults it may cause a condition called osteomalacia, in which calcium is lost from bones so that they become weak. Your doctor may treat these problems by prescribing vitamin D for you. Vitamin D is also sometimes used to treat other diseases in which calcium is not used properly by the body.

Ergocalciferol is the form of vitamin D used in vitamin supplements.

Some conditions may increase your need for vitamin D. These include:

Alcoholism Intestine diseases Kidney disease Liver disease Overactivity of the parathyroid glands with kidney failure Pancreas disease Surgical removal of stomach

In addition, individuals and breast-fed infants who lack exposure to sunlight, as well as dark-skinned individuals, may be more likely to have a vitamin D deficiency. Increased need for vitamin D should be determined by your health care professional.

Alfacalcidol, calcifediol, calcitriol, and dihydrotachysterol are forms of vitamin D used to treat hypocalcemia (not enough calcium in the blood). Alfacalcidol, calcifediol, and calcitriol are also used to treat certain types of bone disease that may occur with kidney disease in patients who are undergoing kidney dialysis.

Claims that vitamin D is effective for treatment of arthritis and prevention of nearsightedness or nerve problems have not been proven. Some psoriasis patients may benefit from vitamin D supplements; however, controlled studies have not been performed.

Injectable vitamin D is given by or under the supervision of a health care professional. Some strengths of ergocalciferol and all strengths of alfacalcidol, calcifediol, calcitriol, and dihydrotachysterol are available only with your doctor's prescription. Other strengths of ergocalciferol are available without a prescription. However, it may be a good idea to check with your health care professional before taking vitamin D on your own. Taking large amounts over long periods may cause serious unwanted effects.


This section provides information on the proper use of a number of products that contain vitamin d and related compounds. It may not be specific to Rocaltrol. Please read with care.

For use as a dietary supplement:

Do not take more than the recommended daily amount. Vitamin D is stored in the body, and taking too much over a period of time can cause poisoning and even death.

If you have any questions about this, check with your health care professional.

For individuals taking the oral liquid form of this dietary supplement:

This preparation should be taken by mouth even though it comes in a dropper bottle. This dietary supplement may be dropped directly into the mouth or mixed with cereal, fruit juice, or other food.

While you are taking alfacalcidol, calcifediol, calcitriol, dihydrotachysterol, doxercalciferol or paricalcitol , your health care professional may want you to follow a special diet or take a calcium supplement. Be sure to follow instructions carefully. If you are already taking a calcium supplement or any medicine containing calcium, make sure your health care professional knows.

The dose medicines in this class will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For alfacalcidol To treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage form (capsules): Adults and teenagers—At first, 1 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For oral dosage form (drops): Adults and teenagers—At first, 1 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For oral dosage form (solution): Adults and teenagers—At first, 1 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For parenteral dosage form (injection): Adults and teenagers—At first, 1 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 12 mcg a week. To treat diseases in which calcium is not used properly by the body: For oral dosage form (capsules): Adults and teenagers—At first, 0.25 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day. For oral dosage form (drops): Adults and teenagers—At first, 0.25 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day. For oral dosage form (solution): Adults and teenagers—At first, 0.25 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day.

For calcifediol To treat diseases in which calcium is not used properly by the body or to treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage form (capsules): Adults, teenagers, and children over 10 years of age—At first, 300 to 350 micrograms (mcg) a week, taken in divided doses either once a day or every other day. Your doctor may change your dose if needed. Children 2 to 10 years of age—50 mcg a day. Children up to 2 years of age—20 to 50 mcg a day. To treat diseases in which calcium is not used properly by the body or to treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage forms (capsules and solution): Adults, teenagers, and children—At first, 0.25 micrograms (mcg) a day. Your doctor may change your dose if needed. For parenteral dosage forms (injection): Adults and teenagers—At first, 0.5 mcg injected into a vein three times a week. Your doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.

For dihydrotachysterol To treat diseases in which calcium is not used properly by the body: For oral dosage forms (capsules, solution, or tablets): Adults and teenagers—At first, 100 micrograms (mcg) to 2.5 milligrams (mg) a day. Your doctor may change your dose if needed. Children—At first, 1 to 5 mg a day. Your doctor may change your dose if needed.

For doxercalciferol To treat an overactive parathyroid gland in patients with kidney failure: For oral dosage form (capsules): Adults—10 micrograms (mcg) three times weekly at dialysis. The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.

For ergocalciferol The amount of vitamin D to meet normal daily recommended intakes will be different for different individuals. The following information includes only the average amounts of vitamin D. To prevent deficiency, the amount taken by mouth is based on normal daily recommended intakes: For oral dosage form (capsules): For the U.S. Adults and teenagers—5 to 10 micrograms (mcg) (200 to 400 Units) per day. Pregnant and breast-feeding females—10 mcg (400 Units) per day. Children 4 to 10 years of age—10 mcg (400 Units) per day. Children birth to 3 years of age—7.5 to 10 mcg (300 to 400 Units) per day. For Canada Adults and teenagers—2.5 to 5 mcg (100 to 200 Units) per day. Pregnant and breast-feeding females—5 to 7.5 mcg (200 to 300 Units) per day. Children 7 to 10 years of age—2.5 to 5 mcg (100 to 200 Units) per day. Children 4 to 6 years of age—5 mcg (200 Units) per day. Children birth to 3 years of age—5 to 10 mcg (200 to 400 Units) per day. To treat deficiency: Adults, teenagers, and children—Treatment dose is determined by prescriber for each individual based on severity of deficiency. To treat diseases in which calcium and phosphate are not used properly by the body: Adults and teenagers—At first, 1000 to 500,000 Units a day. The doctor may change your dose if needed. Children—At first, 1000 to 200,000 Units a day. The doctor may change your dose if needed.

For paricalcitol To treat an overactive parathyroid gland in patients with kidney failure: For oral dosage form (capsules): Adults—1 to 2 micrograms (mcg) one time per day or 2 to 4 mcg three times a week (not more often than every other day). The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor. For parenteral dosage form (injection): Adults—0.04 to 0.1 micrograms (mcg) per kg no more than every other day during dialysis. The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.


If you overdose Generic Calcigra and you don't feel good you should visit your doctor or health care provider immediately.


Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Side effects

The most common side effects associated with Calcigra are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Generic Calcigra if you are allergic to Generic Calcigra components. Do not take Generic Calcigra if you are pregnant, planning to become pregnant, or are breast-feeding. It is not known if this medication appears in breast milk. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Be careful with Generic Calcigra if you have heart disease, kidney disease or kidney stones, coronary artery disease (hardening of the arteries). Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. It can be dangerous to stop Generic Calcigra taking suddenly.

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Atrial natriuretic factor in essential hypertension: echocardiographic and humoral correlates. The role of puerperal endometritis in intrauterine adhesion formation was studied by hysterography in 171 women who had cesarean sections. Analogs of the hormonal form of vitamin D and their possible use in leukemia. Partially purified delta 5-3-ketosteroid isomerase (KSI) from Pseudomonas testosteroni was studied kinetically after solubilization in reverse micelles of aerosol OT (AOT) in isooctane and water, as regards its application to biotechnology. The significance of these results is discussed in terms of the possible changes in membrane lipid metabolism involved in mast cell activation. A range of recent developments that promise a new era in mental health are reviewed, and some old stumbling blocks to the full realization of their potential are considered. The probability of the latter mechanism is suggested by the local increase of radioactivity after the injection of 125I-fibrinogen. Response characteristics of lateral geniculate neurons to flicker stimulation. Such differences may be relevant to viral pathogenesis and provide utility in retroviral vector design.

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Critical aspects of analysis of Micrococcus luteus, Neisseria cinerea, and Pseudomonas fluorescens by means of capillary electrophoresis. lepraemurium to B.663 and delay in development of resistance to isoniazid. Vasomotor reversal was noted with both drugs in the presence of alpha-receptor blockade. It also indicated gaps in the knowledge about chlamydia prevalence in certain subgroups such as men and the general population. Enhanced histamine release from lung mast cells of guinea pigs exposed to sulfuric acid aerosols. Compared to VC, TBI Veterans endorsed significantly greater levels of cognitive and physical fatigue. Overall, the judgement comes clearly in favour of the alternative methods, needless to say in a field where most animal experimentation occurs.

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The most common type of sustained arrhythmia presenting in pregnancy is a supraventricular tachycardia (SVT). The ability of various agents to modify heat induced cytotoxicity and development of thermotolerance is reviewed in light of this model. The use of PCR to help quantify the protection provided by impregnated bednets. Since nearly all planted canola acres in Western Canada and, historically, a majority of planted oilseed acres in the EU, use seed treatments, it is worth examining whether broad use of insecticidal seed treatments (IST) is compatible with principles of integrated pest management (IPM). Minilaparotomy was performed by a conventional technique and the self-retaining abdominal wall retractor (Dexterity Protractor) was placed for the duration of the open surgery. Ketotifen causes a significantly weaker inhibition without inducing histamine release and DSCG is not at all active in this model. He also bequeathed to the Church the basis for an abolutism on sexual issues. 5.The biliary effects of sodium taurodexoycholate in the rat and in the dog are contrasted with its effects in the rabbit, and the differences between the three species are discussed.

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Functional desensitization of the isolated beta-adrenergic receptor by the beta-adrenergic receptor kinase: potential role of an analog of the retinal protein arrestin (48-kDa protein). During a 5-year period (between 1994 and 1999), 126 iliac angioplasties with stent placement (144 stents) were performed in 88 women. Myocardial gene expression is also altered in the adult in response to pathological stimuli and this is thought to contribute to the altered contractile characteristics of the diseased heart. Presumably, previous reports describing detection of DNA in normal plasma were based on the measurement of non-DNAase-sensitive interfering substance. Meperidine and its principle metabolite, normeperidine, were given intravenously to four non-human primates prior to cesarean delivery in an equivalent dose for human parturients. It was found that the presence of 3AB did not increase the repair patch size nor the rate of removal of methylation products from the DNA, which is assumed to equal the rate of repair. This paper will present three hypotheses developed from clinical observations which encourage a re-examination of traditional group perspectives. The location and synthesis of transferrin in mouse embryos and teratocarcinoma cells. Salmeterol, a long acting bronchodilator, in the treatment of asthma.

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Mutagenic effectiveness increased slightly for deuterium and helium ions. Major histocompatibility complex haplotypes and complement C4 alleles in systemic lupus erythematosus. Substitution and internal deletion mutants of T that contain structural alterations in a ten residue, transformation-controlling domain failed to complex with p110-114. A comparison of remedial, failure, and successful secondary school students across self-perception and past and present school performance variables. Infertility patients with endometriosis should be counselled for intensive infertility treatment.

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Analytical performance of the ion-selective electrodes used in the Hitachi 705. Antifungal activity and pharmacokinetics of posaconazole (SCH 56592) in treatment and prevention of experimental invasive pulmonary aspergillosis: correlation with galactomannan antigenemia. High-intensity, pulsed application reduces temporally averaged energy deposition, resulting in mechanical effects, including reversible, localized BBB disruption, which enhances neurotherapeutic agent delivery. 1 mg of BAL administered 1 h prior to 20 microCi of 111In-bleomycin resulted in 2:1 tumor loading and 3:1 liver loading of 111In-bleomycin over controls (p less than or equal to 0.05 at the 2- to 3-hour interval). Conversely, miR-200 was up-regulated during in vitro decidualization of human endometrial stromal cells. Our findings did not corroborate the concept of medullomyoblastoma as a separate nosological entity. Proceedings of the 13th European Meeting on Bacterial Transformation and 5th European Meeting on the Molecular Biology of the Pneumococcus. Other uncommon features observed were early maturation of epiphyseal centres of ossification of phalanges and metatarsals, syndactyly, polydactyly, brachydactyly and symphalangism. Although the total proportion of alpha beta T cells in each organ remained constant, the staining patterns of TCR-alpha beta as shown by immunofluorescence profiles varied.

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These findings suggest that treatment strategies that target both bacteria and oxidative stress will significantly benefit patients with influenza-complicated S. The Notch genes encode a conserved family of receptors that influence developmental fate in many species. Expression of recA-gene dependent SOS functions in Salmonella typhimurium. The remaining infant who preoperatively had significant truncal valve regurgitation was doing fairly well 2 1/2 years after repair. Throughout the past how long after drinking alcohol can you take flagyl five years, 43 cases of noses that lack tip projection have been treated by us with the use of the shield graft technique. A risk of inaccuracy in biochemical analysis of urinary stone-forming salts.

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Selective depletion of human natural killer cells on monolayers of target cells. Aspirations to immortality re-emerge in disguised form in the search for life elsewhere in the universe. Standardization of the bromsulphalein test with respect to body composition. Our new method to produce human impetigo-like blister in Cy-treated adult mice may contribute to disclosing the mechanisms of blister formation in epidermis by S. Analgesic efficacy of oral firocoxib in ovariohysterectomized cats. We then compare it to the jargon and the aphasic productions of the standard neuropsychological examination. The enzymatic acetylation of chloramphenicol by extracts of R factor-resistant Escherichia coli. sumycin 500 mg uses in hindi 36 patients (12 male, 24 female) mean age 8.2 years, (range 1.7-58.3), mean weight 25.5 kg (range 11-67.8 kg). No clear relationship between weevil susceptibility and kernel hardness could be detected, although there was an indication that differences associated with kernel size varied depending on kernel hardness.

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These data indicate the presence of a CNS-targeted antigen-driven response in MS plaques. This finding confirms that the sequence of repolarization is from the epicardium to the endocardium with the middle layers having an intermediate time. Varicella can be prevented when necessary by patient isolation and passive prophylaxis with varicella-zoster immune globulin. Effects of neonatal hypoglycaemia on the nervous system: a pathological study. In the present studies we evaluated the hypothesis that excitatory amino acids, acting at the N-methyl-D-aspartate (NMDA) receptor, contribute to secondary tissue damage following traumatic spinal cord injury. Subareolar mastectomy as a supplementary in the management of carcinoma of the prostate. A young man developed severe epistaxis following trauma that resulted max dose of altace in a Le Fort III fracture of the maxilla.

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To calculate W at a given alveolar ventilation (VA), anatomical dead space (VDanat), pulmonary resistance (RL), and dynamic compliance were measured simultaneously, breath lopressor 100 mg by breath, during various breathing maneuvers. Binding of cellular proteins to the regulatory region of BK virus DNA. Rates of protein synthesis in explanted embryonic chick lens epithelia: differential stimulation of delta-crystallin synthesis. Determination of the structures of both TF components specific for PPD was accomplished by evaluating their activity after incubation with various endonucleases, exonucleases, phosphatases, peptidases and a protease. Preferential loss of 5S and 28S rDNA genes in human adipose tissue during ageing. We describe the facile two-step synthesis of nanotubes that form pure, well-defined, nanostructured materials.

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osteogenesis imperfecta and osteopetroses), the analysis of individuals or families with extreme osteoporotic phenotypes (e.g. Provocative water cystometry failed to demonstrate signs of unstable detrusor but all patients presented a continuous, steep rise of detrusor pressure at the end phase of filling. These results ruled out familial syndromes and suggested that the VHL mutation and the loss of maternal allele on chromosome 11 could have contributed to tumor development. Analysis of Galpha protein recognition profiles of angiotensin II receptors using chimeric Galpha proteins. Earlier studies indicated that the direct DNA oxidant is a derivative of hydrogen peroxide whose formation is dependent on cell metabolism. A short survey is given of the use of ultrasound examinations in neurology. The extent of the effects brought about by silica earth testify that it may be recommended as a reference standard for evaluating the potential health hazard from industrial exposure to dusts containing SiO2. Can medical schools remain the optimal site for the conduct of clinical investigation?.

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