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Calcigard

Calcigard is a calcium-channel blocker. It affects the amount of calcium found in your heart and muscle cells. This relaxes your blood vessels, which can reduce the amount of work the heart has to do. This medicine is used to treat chest pain caused by angina.

Other names for this medication:
Antrolin, Atenerate, Belnif, Calcibloc, Cardipin, Conducil, Cordaflex, Ficard, Marivolon, Nidilat, Nifatenol, Nifcal, Nifebene, Nifecap, Nifecard, Nifeclair, Nifediac, Nifedical, Nifedipina, Nifedipine, Niften, Nipidin, Pabalat, Pressolat, Tenif, Viscard, Zenusin

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Also known as: Nifedipine

Description

Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Adalat PA 10. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Calcigard and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nifedipine dosage information

Side effects

The most common side effects associated with Calcigard are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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Nonviral HVJ (hemagglutinating virus of Japan) liposome-mediated retrograde gene transfer of human hepatocyte growth factor into rat nervous system promotes functional and histological recovery of the crushed nerve. Drugs or vehicles were administered SC 30 min prior to the sample trial. H pylori and HAV infection were identified by the presence of serum antibodies. The intraoperative findings had supposed a primary disease of the retroperitoneal space. ostreatus, because this activity was also produced in the absence of RBBR. Differences in the type of injury according to the cause (explosive or aerosol) can be demonstrated: aerosol burns had less severe consequences. In the lower esophagus, distension above a threshold volume of 5 (3-10) ml (median evista generic usa and interquartile range) induced a traction force together with contractile activity proximal to the balloon and quiescence distally. Moreover, anti-CII antibody levels decreased in the sera of these mice. A double-membraned outer envelope appears to be present outside the chloroplasts of the Phaeophyta and Euglenophyta, but seems to be absent in the other groups of algae.

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To understand endocrine function and to determine which endocrine systems are likely to be affected, 6 patients with mitochondrial encephalomyopathies were studied. A system based on the ability of cells to oxidize very long-chain fatty acids (VLCFA) was developed to select in vitro normal human fibroblasts from fibroblasts of patients suffering from peroxisomal disorders with multienzymatic deficiencies: Zellweger syndrome, neonatal adrenoleukodystrophy, infantile Refsum disease (IRD). The occurrence of fatal and nonfatal cardiovascular events was evaluated in 1088 uncomplicated mild hypertension patients, 626 with low BP variability (SD of daytime systolic BP below the mean of the study population) and 462 with high BP variability (SD of daytime systolic BP above the mean of the study population). Comparative analysis of noninvasive cardiac parameters in the detection and evaluation of adriamycin cardiotoxicity. By virtue of their continual presence and role in the NICU, nurses are in a unique position to support family-centered care. Brainstem auditory evoked potentials (BAEPs) were abnormal in two cases presenting with signs of brainstem dysfunction. These findings suggest that ellipticine interacts directly with topoisomerase II cleocin tablet and that the enzyme dictates the ionic state of the drug in the ternary complex.

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pneumoniae membrane yielded molecules structurally related to LPS which bind to LPS membrane receptors in the absence of serum. Immunohistochemical analysis showed intimal cells to be proliferating smooth muscle cells with surrounding extracellular collagen Type IV. As of 2002, 43 randomized trials of spinal manipulation for low back pain had been published with 30 showing more improvement than with the comparison treatment, and none showing it to be less effective. Means for decreasing emboligenic complications and ischemic damage to the kidneys in the surgical treatment of abdominal aortic aneurysms. In this study, metaphase and array comparative genomic hybridization showed good correlation of aberration profiles in lung adenocarcinoma cell lines from patients with different tobacco exposure. Melphalan-prednisone therapy was interrupted after at least 8 courses in responding patients who achieved a plateau phase, and it was reinstituted at time of relapse.

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These findings suggest that the N-domain of CEA plays an important role in the cell adhesion, and that the domain III is also involved in the binding. Allergen-induced hyperresponsiveness is associated with airway inflammation and appears to involve bradykinin and PAF acutely and growth of airway smooth muscle chronically. Comparison of oxidative phosphorylation of brain and myocardium homogenates of hibernating and homothermic animals in the presence of succinate. And there are essential genes for sperm formation on the Y chromosome. It is interesting that lipid hydroperoxidase activity, which is a measure of hydroperoxide lyase plus allene oxide synthase plus possibly other lipid hydroperoxide-metabolizing activities, was not changed by methyl jasmonate treatment. A geometrical interpretation of the experimental data explains why a bcc bead array is well suited to act as a template for an additional layer of microspheres. Defects were selected by means of two-dimensional transoesophageal echocardiography (2D TOE). These results suggest that proteolytic processing of TIMP-2 plays a role in the regulation of gelatinase A activity in the extracellular matrix. This requires evaluation of the biopharmaceutical properties of the proposed drug from a profile compiled from a set of dissolution tests under different experimental conditions. Asthma prevalence among Chinese immigrant children is poorly understood and attempts to screen these children have produced varied outcomes.

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This enzyme is strongly inhibited by ammonium molybdate, sodium vanadate and cupric ion. Transverse and longitudinal sections, treated for immunohistofluorescent detection of NPY and then processed for NO synthase-related NADPH diaphorase histochemistry, were examined. The advantages and limitations of itraconazole as single drug therapy are outlined. Geographic factors contributing to a high seroprevalence of West Nile virus-specific antibodies in humans following an epidemic. Allograft survival time was prolonged in three BLAD cattle (28, 30, and 72 days) compared to six healthy controls (12-14 days). Fungal community structure was assessed by a molecular approach, fungal automated ribosomal intergenic spacer analysis (FARISA), while fungal biomass was estimated by measuring soil ergosterol content. On the day after parturition, mice recovered faster from morphine-induced hypothermia than controls. Between 2 and 16 weeks, urothelial regeneration and ingrowth of granulation tissue caused a luminal stenosis or occlusion followed by transformation into scar tissue. Dilutions of wine were much more effective in decreasing colony counts than were similar dilutions of bismuth salicylate.

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