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Calasto (Calcitriol)

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Calasto is used to treat and prevent low levels of calcium and bone disease in patients whose kidneys or parathyroid glands are not working normally. It is also used to treat secondary hyperparathyroidism (a condition in which the body produces too much parathyroid hormone and metabolic bone disease in people with kidney disease.

Other names for this medication:
Alfacalcirol, Alfacip, Arcium, Bonestat, Calbovic, Calcicare, Calcikind, Calcirol, Caldix, Calgel, Caltin, Coecoral, Duracal, Fovit, Koncal, Laretol, Lctrol, Minroset, Nutribone, Primacal, Qpcal, Refirm, Ritoca, Romical, Sunmic, Trolec

Similar Products:
Pyridium, Colospa, Sildigra, Eulexin, Neoral, Rhinocort, Prilosec

Also known as: Calcitriol


Generic Calasto is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Calasto are intestine and bone. Generic Calasto receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Calasto may also act on the kidney and the parathyroid glands. Generic Calasto is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Calasto has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Calasto, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Calasto in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Calasto produces other independent beneficial effects. Calasto is also known as Calcitriol. Generic Calasto treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Calasto is Calcitriol. Brand name of Generic Calasto is Calasto.


Generic Calasto is available in capsules (0.25 mcg) and liquid form. Capsules must be swallowed whole. Do not crush or chew them. If you are prescribed the liquid form, use as directed. Follow dosing instructions closely. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. If you want to achieve most effective results do not stop taking Generic Calasto suddenly.


If you overdose Generic Calasto and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Calasto are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Problems in children have not been reported with intake of normal daily recommended amounts. Some studies have shown that infants who are totally breast-fed, especially with dark-skinned mothers, and have little exposure to sunlight may be at risk of vitamin D deficiency. Your health care professional may prescribe a vitamin/mineral supplement that contains vitamin D. Some infants may be sensitive to even small amounts of alfacalcidol, calcifediol, calcitriol, dihydrotachysterol, or ergocalciferol. Also, children may show slowed growth when receiving large doses of alfacalcidol, calcifediol, calcitriol, dihydrotachysterol, or ergocalciferol for a long time.

Studies on doxercalciferol or paricalcitol have been done only in adult patients, and there is no specific information comparing the use of doxercalciferol or paricalcitol in children with use in other age groups.

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Overexpression of a novel zinc-finger protein induces apoptosis in NIH3T3 fibroblasts. Novel functions of smooth muscle cells (SMCs) in the hypertensive pulmonary artery, such as increased motility and proliferation, are supported by the actin cytoskeleton. Serum lactic dehydrogenase: a tumor marker of ovarian dysgerminoma in a female pseudohermaphrodite. It is usually the desire of the researcher to demonstrate a difference in the comparisons made. The incorporation of 131-I by the thyroid glands of acetazolamide-injected embryos was analyzed radioautographically and quantitated on the same 6 mu-paraffin sections, with a thin window Geiger counter.

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In particular, at least three different epitopes present in the 74-kDa protein (presumed to by PDH-E2) are also present in the 51-kDa protein (probably PDH-X), and two in the 52-kDa peptide (possibly BCKDH-E2). inoculation of trinitrobenzene sulfonate (TNBS) hapten-coupled cells. This was a retrospective analysis of 74 consecutive files opened by a malpractice insurer between 1995 and 2000. The associations between WHtR and cardiometabolic outcomes measures were assessed with fractional polynomial regression and logistic regression models. In addition, augmenting peritoneal populations of macrophages with cultured RAW264.7 cells partially protected mice from disease, increasing the survival rate in a dose dependent relationship. In this situation, laparoscopic transhepatic segmental venography or portography may help. In myopathies associated with mutations of the genes encoding the calcium channel RyR1, the extracellular matrix protein collagen VI or the sarcolemmal protein dystrophin (Duchenne Muscular Dystrophy), OxS has been identified as a relevant secondary pathophysiological mechanism. Forty-eight children undergoing endoscopic sinus surgery for chronic sinusitis.

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Facilitation tended to disappear when the same response was not required for the two dimensions, and when competing responses were required, interference appeared with redundant dimensions (negatively correlated stimulus sets). In all species, a fraction of the triose was recycled through fructose phosphates to glucose 6-phosphate. The structures of these compounds were elucidated by physicochemical data and spectral analyses, and found to be new compounds. This is the first report of an avian babesoid on this continent. Malignant lymphoreticular neoplasias of the digestive tract (lymphosarcoma, reticulosarcoma, reticulohistiocytic lymphoangioblastoma, etc.). Age-dependent injury tolerance exemplified by fatal pedestrian accidents. The plasma concentration pattern of active constituents of Shosaiko-to extract granule varied with the time of administration, but there was no significant difference in the maximum plasma concentration or AUC of active constituents depending on the administration.

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The current analyses suggested that acceleration to 6 daily fractions per week could significantly improve the progression-free rate for NPC without excessive late toxicity. In vivo studies were performed to determine if alpha-adrenergic coronary vascular constriction is enhanced in the presence of atherosclerosis. In those patients with fluid detected by both techniques, estimated size of the effusion tended to be somewhat larger by NMR. The effects of the specific N-methyl-D-aspartic acid (NMDA) receptor antagonist MK-801 (dizocilpine, 0.075 mg/kg, i.p.) on swim-stress-induced analgesia (SSIA) were studied in control (C) mice and in mice selectively bred for high (HA) or low (LA) SSIA. Positive fibrinogen binding was detected in seven of the strains. As previously described, the most D proximal VH genes are also used most frequently. We show that these functional consequences of the differences in dendritic geometries can be explained quantitatively using simple anatomical measures of dendritic branching patterns, which are captured in a reduced model of dendritic geometry. Given the increasing availability of autoantibody testing, this review explores the phenotypes associated with different autoantibodies in juvenile-onset myositis and the potential clinical utility of autoantibody testing. Pseudomyxoma peritonei: possible prevention of mucinous ascites by peritoneal lavage. Clinical studies on surgical treatment of renal hyperparathyroidism.

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Management of a traumatically avulsed skin-flap on the dorsum of the foot. DNA topological labeling can be done both in solution and, for longer templates, within the agarose gel plug. The approach of the study was prospective, but because of the large amount of retrospectively included patients, the design of the study is overall retrospective. Two-dimensional gel electrophoresis and peptide map analysis demonstrate that the A-like antigens of rat are distinct from the E-like antigens. Ethylnitrosourea was used as a model mutagen to determine the time at which the most mutants and chromosomal aberrations could be detected. A rare case of CPA tumor causing contralateral trigeminal neuralgia was encountered in our hospital. The human platelet-derived growth factor (PDGF) A-chain locus was characterized by restriction endonuclease analysis, and the nucleotide sequence of its exons was determined. Negative priming from masked words: retrospective prime clarification of center-surround inhibition?. Many approaches to percutaneous ureteral occlusion have been used with variable success, including coils and gelatin sponge, isobutyl-2-cyanoacrylate, detachable balloons, radiofrequency electrocautery, ureteral clipping, and solid and soft polymer agents.

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To demonstrate the benefits of a noninvasive method of treatment for an ingrowing nail using gutter splint and formable acrylics and to present a current understanding of the disease pathophysiology. The PVS should be reserved for patients with disabling, truly refractory ascites. Fractional contrasts and minimum detectability for air, several concentrations of Renografin-60, and aluminum were studied using phantoms of various thicknesses. These results provided strong evidence that the large increase in surface areas of the drug nanoparticles could overcome the narrow absorption window and lead to rapid in vivo dissolution, fast absorption, and increased bioavailability. Cisplatin-GG adducts are preferentially recognized by mismatch repair proteins and some damage-recognition proteins, and this differential recognition of cisplatin- and oxaliplatin-GG adducts is thought to contribute to the differences in cytotoxicity and tumor range of cisplatin and oxaliplatin.

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Glucose metabolism in fat cells stimulated by insulin and dependent on sodium. Pittard, James (School of Microbiology, University of Melbourne, Victoria, Australia), and B. 2004) dealt with one of the issues that a sub-group of athletes need to consider before deciding to take supplements - the risk of a positive drug test if the product contains substances banned by the anti-doping codes under which their sport is conducted. In adult rats under urethane anesthesia, a vast majority of spontaneously active neurons in the frontoparietal cortex undergo a prolonged depression of their firing rate upon microiontophoretic application of 5-HT. Surface IgG was detected on a small proportion of the cells, and they were distinguished from the Fcgamma receptor-bearing cells in the metrial gland of deciduomata of pseudopregnancy. Humoral and cellular immune responses to laryngeal carcinomas suggest the presence of tumor-associated antigens on the surface of larynx carcinoma cells. In vitro release experiments were conducted using slices of hypothalami obtained from male rats whereas the in vivo release of these peptides was assessed in push-pull perfusates of the arcuate-median eminence (ARC-ME) region of the medial basal hypothalamus of chloral hydrate-anaesthetized male rats. In situ characterization of such T cell clonotypes revealed that within the early stages of T cell activation, i. EEG Analysis During Active and Assisted Repetitive Movements: Evidence for Differences in Neural Engagement.

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Changes in the forehead and sole deep temperature during cardiopulmonary bypass for congenital heart diseases. The specific binding of vasoactive intestinal peptide (VIP) to its specific receptors as well as the stimulatory effect of the neuropeptide on cyclic AMP accumulation were studied in jejuno-ileal epithelial cells from 14-, 20- and 60-day-old rats. The method of polycardiography can thus not be recommended for exact intraindividual differentiation of left vetricular functional ability. Thus, heterogeneity of dopamine decrease appears to be closely related to the structure of microvasculature. NB/70K does not appear to contain normal serum, normal ovary, normal lung, or carcinoembryonic antigen-like cross-reacting antigenic determinants as measured by radioimmunoassay. However, signals in subrabasal cells were detected more frequently with biotin- than with 35S-labeled probes. Invaginations of the nuclear membrane of the Purkinje cells in the adult rat.

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Emotional labor, defined as the process of regulating feelings and expressions as part of the work role, is a major characteristic in call centers. We sought to objectively assess the internal and external validity of patient-derived xenograft (PDX) models as a platform in pre-clinical research into colorectal cancer (CRC). When the migratory cell traverses approximately half of its length through the endothelial cell, actin appears prominent in the caudal region of the cell. Racial differences in cancer of the male breast--15 year experience in the Detroit metropolitan area. In evaluating the damage and recovery extent after accidental irradiation, we consider it expedient to complement the biological dosimetry with the indices studied work including the determination of DNA and RNA concentrations in blood of irradiated human beings. The use of sonography and amniocentesis when AFP levels are abnormally high, and the risks to mothers and fetuses, are described. Of these 29 mutants, 9 have single base substitutions, 1 has a small duplication, 17 have simple deletions, 1 has a deletion with additional bases inserted at the deletion site, and 1 has no change in the gpt coding sequence. A note on developmental trends in the symbolic play of hospitalized profoundly retarded children. The use of recombinant allergens for the diagnosis and immunotherapy of allergy may offer several advantages over allergen extracts. The Plant-Derived Bauhinia bauhinioides Kallikrein Proteinase Inhibitor (rBbKI) Attenuates Elastase-Induced Emphysema in Mice.

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We used statistical analysis of published HIV-1 genomic sequences to examine the role of natural selection in between-host evolution of CTL epitopes. However, these receptors serve complementary roles, such that double-knockout MIGIRKO mice displayed a marked reduction in muscle mass that was linked to increases in proteasomal and autophagy-lysosomal degradation, accompanied by a high-protein-turnover state. Improvement of the radioallergosorbent test (RAST) sensitivity by using an antibody specific for the determinant D epsilon 2. Refs 4,5), these aspects have been largely ignored for the human filarial parasite provigil mg Loa loa. Both events occur before the decline in mRNA abundance, and polyribosome association is rapidly reversible if plants are re-illuminated. The dual infections may produce alterations in the immunoregulatory system that would lead to depletion of T suppressor cells.

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112:589-602), they are localized predominantly in the trans-Golgi cisternae and the trans-Golgi network in epidermal and peripheral root cap cells. Prevalence of cryoglobulinemia in hepatitis C virus (HCV) positive patients with and without human immunodeficiency virus (HIV) coinfection. We revised the clinical histories of the infants diagnosed with bacteremia and classified them into two groups: a) those with vertically transmitted bacteremias, according to the recommendations of the Castrillo Group, and b) those with suspected early onset neonatal sepsis in whom blood culture was positive and analytical data suggested bacterial infection but who showed no clinical symptoms of vertically transmitted sepsis. Data were collected on study characteristics, and the modality, timing, and findings of thoracic imaging. In vivo platelet hyperactivity and factor VIII related antigen increase long after myocardial infarction. Habituation: a model phenomenon for the study of neuronal substrates of behavior. The C3435T polymorphism was found to correlate with the activity of P-glycoprotein. Recently, coronary artery bypass graft without cardiopulmonary bypass, which is named minimally invasive coronary artery bypass, has received attention from cardiac surgeons.

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However, substantial problems remain before serious considerations of attempting gene transfer in humans can be made. A sequence with 37-of-38-bp homology to the inverted repeated sequences of Tn21 and an open reading frame with strong homology to the MerR regulatory protein was identified outside of the region required for mobilization. There was only a partial correlation between the results of both test systems. Flail Tricuspid Valve in an Adult Patient with Congenitally Corrected Transposition of the Great Arteries. Sketches of otohistory part 4: a cell by any other name: cochlear eponyms. Because protein kinase A, protein kinase C, and calcium influx in the rat adrenal medulla are all stimulated following splanchnic nerve stimulation, the differential regulation of neurotensin and substance P biosynthesis following stimulation of these three pathways was examined in bovine chromaffin cells in vitro. Nine baseline co-variables were robust: painDETECT score, intensity of burning and painful attacks, SF36 Health Survey score (MCS, PCS), EuroQol-5, Hospital Anxiety/Depression Scale. Clinical trial patients are highly motivated but may encounter difficulty in taking study medication regularly when treatment burden is substantial. There was a significant increase in residence times in the case of lesion of the mucosae themselves. Various lesions on OCT suggestive of activity correlated with changes in the vascular structure of OCTA to confirm suspicion of clinical activity.

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Disturbances of lipid metabolism play an important role in the course of demyelination. Thus, Hsp70SSA1 and YDJ1p interact functionally in the execution of Hsp70SSA1 chaperone activities in the eukaryotic cell. The influence of memory for prior instances on performance in a conflict detection task. Association of bidirectional ventricular tachycardia with familial sudden death syndrome. The study confirmed the screening value of TCD among the sporanox tablet general population in urban China. The Sexual Health Inventory for Men (SHIM) was also administered at these times.

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Newer knowledge concerning a protective antigen of Erysipelothrix rhusiopathia. The experimental class III antiarrhythmic drug, L-768673, prolongs the refractory period of cardiac myocytes by selectively blocking the slow-activating delayed rectifying potassium (I(Ks)) channel. Authors, editors, and readers in the brave new (electronic) world. This article describes the general principles of use for endovascular devices and details the features and results for the devices in current use. Circulating activities during constant infusion of heparin or a low molecular weight derivative (enoxaparine): failure to demonstrate any circadian variations. Prophylaxis and treatment of thromboembolisms in surgery and obstetrics.

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In Experiment 2, intracerebral microdialysis was used to examine whether alterations in dopamine (DA) or monoamine metabolites in the nucleus accumbens or caudate-putamen accompanied the lesion-induced changes in locomotion. Monoclonal anti-idiotypes induce neutralizing antibodies to enterovirus 70 conformational epitopes. At the ultrastructural level the effect of advanced nuclei on the less advanced ones was evident with respect to chromosome condensation and nuclear envelope breakdown. Human endometrium and early pregnancy decidua harbor a considerable and diverse population of antigen-presenting cells (APC). The amount of noradrenaline released per nerve impulse from renal sympathetic nerves can be modulated through specific prejunctional receptors. This study opens up new avenues for using curcumin, in combination with other antioxidants, as a component in storage solutions. PCNA was levaquin daily dosage expressed in the vascular endothelium as well as in the corneal cells. The antagonist had no effect on pressor responses to phenylephrine (PE). Myocarditis and dilated cardiomyopathy: different stages of the same disease?. Each selected ram was then exposed to approximately 30 estrus-synchronized ewes for a 9-d period.

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Histologically, this neoplasm heterogeniously consisted of poroma-like, sebaceous and follicular epithelial components. Immunohistochemical Expression of B Cell Lymphoma2 with Clinicopathological Correlation in Triple Negative Breast Cancers in Northern Pakistan. This report is the first systematic evaluation of the effects of prolonged weightlessness on the bipedal postural control processes during self-generated perturbations produced by voluntary upper limb movements. Typically, Chlamydia trachomatis causes a sterile but inflammatory oligoarthritis. The technique has the advantage that the need for mandibular resection may be avoided, although this procedure is still available if the primary treatment fails. More efforts are needed to improve national survival rates in future. Our results confirm that the previously described alanine 113 to proline substitution is responsible for the altered properties of TBG-M. Interaction potential of Carmegliptin with P-glycoprotein (Pgp) transporter in healthy volunteers. Hence, the genes responsible for hereditary lymphedema are of great interest due to the potential for providing insights into the mechanisms of lymphatic development, the diagnosis, prevention and treatment of lymphedema, and lymphangiogenesis during tumor growth.

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Our results, along with other recent studies, demonstrate that predictions of molecular effects capture some important aspects of disease. In the diabetic group, the relaxation responses of corpus cavernosal strips to omeprazole were comparable with those of the control group, whereas the relaxation responses to electrical field stimulation and carbachol were impaired. Selenium effectively prevented BP after 7 days exposure to toxic levels of methyl mercury chloride. Platelets in tumor metastasis: generation of adenosine diphosphate by tumor cells is specific but unrelated to metastatic potential. In the barn owl (Tyto alba), the posterior nucleus of the ventral lateral lemniscus (VLVp) is the first site of binaural convergence in the pathway that processes interaural level difference (ILD), an important sound-localization cue. Although the precise biochemical mechanisms responsible for this remain to be fully defined, there is now evidence accumulating from a number of laboratories that functional receptors for these bacterial products do exist and may contribute to the initial triggering event. Condition of the skin and capillaroscopic picture of the ungual folds in workers at petroleum distribution centers.

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Comparison of the results of vegetological studies by the electrophoretic method according to Baraboje and modified by the reaction according to Manoilova. Asymptomatic nerve hypertrophy in lepromatous leprosy: a clinical, electrophysiological and morphological study. Moreover, it was concerned not with antibody against mumps virus antigens but with alpha-interferon (IFN-alpha) produced in the mixture of human PBML and Pc-10/MpV cells, since this cellular cytotoxicity was suppressed by anti-human IFN-alpha rabbit serum. IgG-mediated intravascular hemolysis and nonoliguric acute renal failure complicating discontinuous rifampicin administration. Hazards of antibiotics in patients with impaired kidney function. These quantitative differences in motoneuron dimensions may in turn be reflected by differences in the electrotonic properties of motoneurons in different motoneuron nuclei. Reviewed available studies of the impact of fetal cocaine exposure on child medical and developmental outcome, as well as the current status of clinical psychological interventions and research strategies.

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Comparative studies on microbial and chemical modifications of trichothecene mycotoxins. Electrical properties of the rabbit urinary bladder assessed using gramicidin D. Even when guided by SPECT/CT planning of nodal resection in the head-and-neck area is challenging due to the many critical anatomical structures present within the surgical field. Due to the size of the tumor, endoscopic mucosal resection alone was not feasible and consequently a combination of endoscopic resection with polypectomy snare and argon plasma coagulation was applied. These results show that the apparatus is useful in estimating working memory in mice with little effort. theophylline 100mg er tablets

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