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Budeprion (Bupropion)

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Budeprion is an atypical antidepressant primarily used to treat major depressive disorder and to support smoking cessation. Budeprion is an effective antidepressant on its own, but it is also popular as an add-on medication in the cases of incomplete response to the first-line selective serotonin reuptake inhibitor (SSRI) antidepressant.

Other names for this medication:
Aplenzin, Budeprion, Bupdep, Bupraset, Bupron, Bupropion, Ession, Nicotex, Smoquit, Unidep, Zyban

Similar Products:
Daklinza, Lodine, Feldene, Detrol, Risperdal, Motrin, Rocaltrol, Terramycin

Also known as: Bupropion


Wellbutrin XL is an antidepressant used to treat major depressive disorder and seasonal affective disorder. The Zyban brand of bupropion is used to help people stop smoking by reducing cravings and other withdrawal effects.


Take Wellbutrin exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. Too much of this medicine can increase your risk of a seizure.

Do not crush, chew, or break an extended-release tablet. Swallow it whole.

You should not change your dose or stop using Wellbutrin suddenly, unless you have a seizure while taking this medicine. Stopping suddenly can cause unpleasant withdrawal symptoms.

Do not stop using Wellbutrin suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.

Some people taking Wellbutrin have had high blood pressure that is severe, especially when also using a nicotine replacement product (patch or gum). Your blood pressure may need to be checked before and during treatment with bupropion.

This medicine can cause you to have a false positive drug screening test. If you provide a urine sample for drug screening, tell the laboratory staff that you are taking bupropion.

Store at room temperature away from moisture and heat.

Detailed Wellbutrin dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of bupropion can be fatal. Overdose symptoms may include muscle stiffness, hallucinations, fast or uneven heartbeat, shallow breathing, or fainting.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F), and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Budeprion are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not use Wellbutrin if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

You should not take Wellbutrin if you are allergic to bupropion, or if you have:

a seizure disorder; an eating disorder such as anorexia or bulimia; or if you have suddenly stopped using alcohol, seizure medications, or a sedative (such as Xanax, Valium, Fiorinal, Klonopin, and others).

Do not use an MAO inhibitor within 14 days before or 14 days after you take bupropion. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Do not take Wellbutrin to treat more than one condition at a time. If you take bupropion for depression, do not also take this medicine to quit smoking.

Wellbutrin may cause seizures, especially if you have certain medical conditions or use certain drugs. Tell your doctor about all of your medical conditions and the drugs you use.

To make sure this medicine is safe for you, tell your doctor if you have ever had:

a head injury, seizures, or brain or spinal cord tumor; narrow-angle glaucoma; heart disease, high blood pressure, or a heart attack; diabetes; kidney or liver disease (especially cirrhosis); or depression, bipolar disorder or other mental illness; or if you drink alcohol.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor will need to check your progress at regular visits while you are using Wellbutrin. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Ask your doctor about taking Wellbutrin if you are pregnant. It is not known whether bupropion will harm an unborn baby. However, you may have a relapse of depression if you stop taking your antidepressant. Tell your doctor right away if you become pregnant. Do not start or stop taking bupropion without your doctor's advice.

If you are pregnant, your name may be listed on a pregnancy registry to track the effects of bupropion on the baby.

It may not be safe to breastfeed while using Wellbutrin. Ask your doctor about any risk.

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Conventional content analysis was used to identify and group the common themes that emerged from the focus group discussions. Our patient has been treated over the years with mild topical corticosteroids, usually with favorable results. HIV protease inhibitors have been suggested to have a direct role in modulating adipocyte differentiation. Assessed value of high-sensitivity cardiac troponin T for cardiovascular disease among CKD patients. Last March, in a single issue New England Journal of Medicine published 3 studies that evaluated the efficacy of endovascular treatment for ischemic stroke, leading to a heated controversy between neurologists and interventional neuroradiologists. However, recent genome-wide association studies on CAD have not proven these associations. Age standardised smoking prevalence rates were calculated by gender, ethnicity and socioeconomic deprivation using the WHO Population Standard. Heritability estimates for size were moderate to high from 13 to 19 months of age, ranging from 0.36 to 0.50, and lower from 21 months to spawning at 24 months, ranging from 0.17 to 0.32. The resulting delineation contains both mass and shape information. Cutaneous gnathostomiasis with recurrent migratory nodule and persistent eosinophilia: a case report from China.

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The primary structure of transition protein 4 (TP4) from boar late spermatid nuclei was determined by automated Edman degradation of S-pyridylethylated protein and of peptides generated by cleavage with Staphylococcus aureus V8 protease, lysyl endopeptidase and CNBr. The presence of epilepsy, although benign, in childhood is associated with adaptive problems of the child. Stimuli affecting the migration of the microfilariae of Dirofilaria aethiops, D. However, the studies showing this association have been relatively small. Second, accurate artificial neural network (ANN) models were built to predict drug release profiles for fifteen polymers located outside the initial design space. Preparation and characterization of monoclonal antibodies directed against four structural components of canine distemper virus.

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In this contemporary cohort of children born extremely premature and evaluated at school age, boys had higher prevalence of cognitive, neurologic, and behavioral deficits than girls. Combat experience and interpersonal violence were consistently cited as leading causes of PTSD and related symptoms. This finding has given opportunities for pursuing promising applications. Technique to displace bowel loops in MRI-guided high-intensity focused ultrasound ablation of fibroids in the anteverted or anteflexed uterus. The comparative transcriptome analysis from three culture conditions revealed the landscape of gene-altered expressions responsible for lipid accumulation. Malformations of cranial base structures and pituitary gland in prenatal Meckel syndrome. Passage of an isolate of pathotype 3, originally from an Australian grasshopper (Praxibulus sp.), through a North America grasshopper resulted in no differences in the resultant RAPD fragment patterns. Using a radiolabelled peptidyl chloromethane inhibitor of rat liver proteasomes we have directly identified RC7 as a catalytic component. This study used a previously validated large animal model of polymicrobial infection to assess the patency and infectious resistance of a novel, antibiotic-impregnated graft material compared with PTFE and Dacron.

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To determine the rates of relapse of acne vulgaris and retrial of isotretinoin after high cumulative-dose treatment and the changes to the adverse effect profile. The selection of breast cancer patients as candidates for nipple-sparing mastectomy (NSM) is dependent on the preoperative detection of neoplastic involvement of the nipple-areola complex (NAC). Comparative evaluation of galactomannan optical density indices and culture results in bronchoscopic specimens obtained from neutropenic and non-neutropenic patients. To evaluate surgical complications, patterns of lymph node metastases, and calcitonin response to compartment-oriented lymphadenectomy in patients with primary or recurrent medullary thyroid carcinoma (MTC). Seasonal changes in the circadian dynamics of the peripheral blood composition in golden hamsters. Calcified subdural hematomas in childhood: report of two cases. Male concussed athletes were significantly impaired in recognizing negative emotions and needed more emotional intensity to correctly identify these emotions, compared to same-sex controls. Basal bodies across eukaryotes series: basal bodies in the freshwater planarian Schmidtea mediterranea. Patients prescribed psychotropic medications within primary care are at risk of suboptimal monitoring. Role of response variables in recognition and identification of complex visual forms.

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In patients with a cancer-free but dysfunctional larynx, both surgical and nonsurgical treatment options, including hyperbaric oxygen, are available for attempted salvage. In the presence of pokeweed mitogen (PWM), human LAK cells induced DNA fragmentation of two leukemic cell lines (U937 cells and Raji cells) and two solid tumor cell lines (SW1116 cells and Hep-2 cells), a hallmark of apoptosis. Characterization of a Salmonella typhimurium mutant defective in phosphoribosylpyrophosphate synthetase. REFLEX PULMONARY VASOCONSTRICTION DUE TO STIMULATION OF THE AORTIC BODY BY NICOTINE. Potential pollution of sediments was evaluated using potential load index, modified degree of contamination, and potential ecological risk index. ARFI method with specific VTI features could be a very useful tool in the differentiation of malignant microcalcifications in thyroid nodules. We have produced and purified the FGF-8 protein, and shown that it will substitute for the AER in maintaining limb bud outgrowth in mouse embryos from which the AER has been surgically removed. Despite recent modifications, the clinical definition of the acute respiratory distress syndrome (ARDS) remains non-specific, leading to under-diagnosis and under-treatment. The featured model can provide individualized estimates of the risks of postoperative complications based on preoperative conditions and can potentially be used as an adjunct in decision making in cerebrovascular neurosurgery.

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Responsiveness was assessed by change in questionnaires following treatment for an acute respiratory exacerbation. Parents of children with holoprosencephaly often have been told that their children will die within days or weeks. Unconditional respect conceptualized as an attitude suggests that unconditional respect and conditional respect are additive, whereas unconditional respect conceptualized as a personality trait suggests that people who are high on unconditional respect afford equal respect to all humans regardless of their merits. To evaluate the effectiveness of exercise interventions on the rate of falls and number of fallers in care facilities. Type 1 showed a diffusely high activity of the tracer in the whole skeleton especially in the skull: secondary hyperparathyroidism pattern. Experimental study of coronary reactive hyperemia--effects of hypothermia and potassium cardioplegia.

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Our results may have implications in the design of therapeutic strategies in cancers driven by these oncogenes. There are several tests to diagnose paracoccidioidomycosis, but they have many limitations such as low sensitivity, high cost, and a cross-reacting problem. In vitro capacitation of boar ejaculated spermatozoa: effect of conditioned media prepared from preincubated sperm suspension. The clinical significance of FL is incompletely understood at present. Here, we show atenolol 50 mg tab picture using immunohistochemistry and immunofluorescence that cells positive for ANGPTL4 are scattered along the epithelial layer in the human small and large intestine. Results of the nationwide Pertussis Epidemiology Study implemented by Department of Epidemiology NIPH-NIH in 2009-2011 showed a high proportion of cases of whooping cough in adults whose only symptom of Bordetella pertussis infection was long lasting cough.

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By 3-4 months following MPTP treatment the animals had largely recovered from their akinesia, but the caudate nucleus and putamen dopamine, HVA and DOPAC content remained low. The resulting gradients in tissue stress are measured in terms of interstitial fluid pressure using a servo-null system. The recently cloned murine (p235) and Schizosaccharomyces pombe FAB1 homologues both restored basal PtdIns(3,5)P(2) synthesis in Deltafab1 cells and made PtdIns(3,5)P(2) in vitro. Despite this decrease in activity, the inhibitory tyrosine phosphorylation of p34cdc2 was decreased, suggesting that other factors are responsible for the decreased kinase activity. The compounds were evaluated for their effects on the respiratory burst of human whole blood and isolated human polymorphonuclear leukocytes (PMNs) using luminol- and lucigenin-based chemiluminescence (CL) assays, and their effect on chemotactic migration of PMNs was assessed using the Boyden chamber technique. Peptic ulcer disease, Helicobacter pylori, and the surgeon: changing of the guard. Histological studies on lymphatic apparatus in human adipose tissue. Most amputees experience referred sensations, known as a phantom hand map, on the residual forearm, where touch on specific areas is perceived as touch on the amputated hand. Our results (1) indicate that recurrent spontaneous seizures have an adverse effect on global white matter growth and (2) show that individual whole brain white matter volume can be accurately determined using a combination of multiparametric MRI and supervised segmentation models, offering a powerful tool to assess white matter volume changes in preclinical studies of neurological disease. Safety assessment of genetically modified milk containing human beta-defensin-3 on rats by a 90-day feeding study.

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Of the 2 patients who underwent a laparotomy, one patient did not have any symptoms or signs that correlated with the intra-operative findings. Four weeks after AMI, patch closure of VSP through right ventricular approach and MAP through trans-atrial approach and also aorto-coronary bypass to left anterior descending artery were performed. The objective of this study was to evaluate any pharmacokinetic interactions between pelubiprofen and eperisone hydrochloride in healthy Korean male volunteers. Population genetics of the STRs vWA, D3S1358 and FGA in the Pomerania-Kujawy region of Poland. Our results uncover important differences in intracellular versus extracellular initiated S100A8 and S100A9 signaling cascades and their effects on mammary epithelial upper gi bleed protonix dosing growth. During 1980-1987 a total of 332 subjects in the study population had their first subarachnoid haemorrhage. Relation of growth of hair on digits to the severity of ischemia. The comet assay is more sensitive than standard DNA flow cytometry to detect early DNA fragmentation events occurring during apoptosis.

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Oral proliferative verrucous leukoplakia: A case report with an update. The low calcium affinity and failure of the model ParvCD site to bind magnesium may be due to higher enthalpic costs of chelation by the -X glutamate. To investigate the growth inhibition effect, cytotoxicity and apoptotic induction of harringtonine (HT) in human acute promyelocytic leukemia (APL) NB4 cells,and the related mechanism. OFL was assessed by measuring psychophysical tuning curves using a forward-masking paradigm. To study the pollen flow of cacao, we estimated the degree of self-pollination and pollen dispersal distances as well as gene flow between wild and cultivated cacao (Theobroma cacao L.). The ADHD group showed a significant increase in glutamate in the ACC compared to controls, no significant differences in metabolites were observed in the DLPFC. Strikingly, in some instances which-way information becomes erased by introducing classical uncertainty in the internal degree of freedom. Hepatitis B is a disease of public health importance in Solomon Islands and emphasize the need for integrated preventative interventions for its control. We conducted a quasi-experimental study using a 2-way (state and year) fixed-effect method.

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New Raffaelea species (Ophiostomatales) from the USA and Taiwan associated with ambrosia beetles and plant hosts. Computed tomography scanning with intravenous contrast is maybe the most accurate modality for diagnosis of intussusceptions in adults, and treatment is usually surgical resection without reduction, since most of the colonic lesions are malignant. The kinase mTOR modulates the antibody response to provide cross-protective immunity to lethal infection with influenza virus. Here, we asked whether an immune challenge causes oxidative stress in free-ranging bats, measuring two oxidative stress markers. It is harmful to human beings and animals, and causes irritation of the skin, eyes and respiratory tract. Finally, our data suggest that when possible, observers inhibit regions of color space rather than individuating specific colors and adjusting the level of inhibition for a particular color accordingly. Induction of protective immunity against Schistosoma mansoni by a nonliving vaccine is dependent on the method of antigen presentation. Adopting this new method may improve the timely collection of cases in other countries. Oxidation of methionine residues of recombinant human interleukin 2 in aqueous solutions. Malignant lymphoma of the gastrointestinal tract: roentgenographic considerations.

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