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Buconif (Nifedipine)

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Buconif is a dihydropyridine calcium channel blocker. Buconif is used to: treat high blood pressure (hypertension), prevent chronic stable angina (chest pain). Buconif was the first calcium channel blocker to be shown to significantly reduce the development of new overt heart failure in patients with coronary artery disease. Excellent blood-pressure control in recent clinical trials has been shown to result in significant protection against stroke. Buconif works by opening up blood vessels in the body to lower blood pressure and improve the supply of blood and oxygen to the heart. Calcium channel blockers do not change the amount of calcium in your blood or bones.

Other names for this medication:
Addos, Adefin, Afeditab, Amarkor, Belnif, Calcheck, Calcibloc, Calcigard, Cardules, Casanmil, Citilat, Conducil, Coracten, Cordafen, Cordaflex, Depin, Duranifin, Epilat, Hexadilat, Jutadilat, Lemar, Menoprizin, Nedipin, Nefelid, Nifangin, Nifecap, Nifecard, Nifecardia, Nifeclair, Nifed, Nifedalat, Nifediac, Nifedical, Nifedip, Nifedipina, Nifedipine, Nifedipress, Nifeslow, Nifin, Niften, Nilol, Nipidin, Noviken, Nyefax, Oxcord, Pabalat

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Adalat. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Buconif and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Adalat dosage information

Side effects

The most common side effects associated with Buconif are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of nifedipine in the elderly. However, elderly patients are more likely to have age-related kidney, liver, or heart problems which may require caution and an adjustment in the dose for patients receiving nifedipine.

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Biomicroscopy of the ciliary margin of the eyelid in normal conditions and in nonspecific blepharitis. Given the rapid pace of research in this field, it will likely be incorrect or incomplete in at least some respects by the time of publication. In this review, we will discuss detection-oriented derivatization as well as the application of mobile phase additives to enhance the sensitivity of detection in liquid chromatograph/atmospheric ionization/mass spectrometry (LC/API/MS), focusing in particular on the applications involving small molecules in bio-matrices. Women with phenylketonuria differed from their acquaintances and diabetic women in many respects, suggesting that special programs are needed. Rupture of the renal artery after cutting balloon angioplasty in a young woman with fibromuscular dysplasia. Effect of x-ray tube potential on image quality and patient dose for lumbar spine computed radiography examinations. Filtering plasma to remove the heparin in may produce a nonaggregating negative control channel. Changes in intraosseous pressure at the distal femoral epiphysis induced by variations in knee-joint position and intracapsular saline infusion. In this study, we cloned, expressed, and tested functional effects of a naturally occurring splice variant of human IL-4, called IL-4 delta 2. Pharmacokinetics of ranitidine and nizatidine in very elderly patients.

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Intrinsic analgesic activity of human beta lipotropin in rats: comparison with other opioid peptides. The phenomenon of in vitro activation of the classical complement pathway at low temperatures (4-21 degrees C) is known as cold activation, and has been suggested to be associated with non-A, non-B hepatitis. In this study, pentobarbital/d5-pentobarbital is used as the exemplar analyte/deuterated analog pair to illustrate the ion selection and evaluation procedures. Antibody response was the basis for diagnosis, although polymerase chain reaction testing has been useful in research settings. A case of mycobacterial lymphadenitis due to Mycobacterium malmoense was recently diagnosed in a 5-year-old girl. Here we have studied the dendritic morphology of the same motoneuron pool after nerve-crush at maturity in order to correlate the observed alterations in morphology with physiological findings. Reservoirs are only occasionally useful but shunts are frequently lifesaving despite complications. Two patients have been successfully treated by an operation which comprised the removal of the fistula and an intra-thoracic esophago-jejunal anastomosis. The benefit-cost equation acknowledges that many parameters of cost and probability are not definitive to date yet illustrated major points for discussion. These results have shown that the administration of exogenous NGF may be essential for inducing functionally significant regenerative mechanisms in diabetic neuropathy through maintaining the permeability of the barrier properties of the peripheral nerve.

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Evaluation of an alternative method of blood sampling from arterial cannulae. Management of malignant pleural effusions with pleuroperitoneal shunting. For lesions located in critical cortical areas, cerebral teleangiography under stereotactic conditions provided the coordinates of the vascular elements related to the structures and adjacent to the lesion without X-ray distortion. Personality changes in tuberculosis (Preliminary report on an attempt, by means of psychodiagnostic methods, to arrive at objective conclusions). A two-week course, designed to involve mid-level officers from at least six government ministries in the planning and implementation of such projects, has been tested in Ghana, the United Republic of Tanzania, and Zimbabwe. These results demonstrate the heterogeneous nature of the pp72 and that p72syk is activated after Fc epsilon RI aggregation. The use of allogeneic bone in scoliosis surgery is justified in view of the acceptable pseudarthrosis rate and the low incidence of infection. More importantly, the semi-empirical parameter, F, introduced in the PCH model for one-photon excitation to correct for the non-Gaussian shape of the observation volume, shows small variations with different bin times. Normal secretion and action of the gut incretin hormones glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in young men with low birth weight.

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The effect of augmented sensory feedback on the control of salivation. Breast lymphoma: favorable prognosis after treatment with standard combination chemotherapy. One thousand and six alive newborns born after normal single pregnancy, and without severe neonatal diseases were included. The influence of protein-calorie malnutrition on the pattern of pre-school childhood diseases. In this cancer-oriented study, we detail an SNP mining strategy based on the analysis of expressed sequence tags among publicly available databases.

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Interview with Moncef Zouali: What is going to happen tomorrow in the field of lupus anti-DNA antibodies?. Pesticide transformations: production of chloroazobenzenes from chloroanilines. We tested the hypothesis that human donor liver may be predisposed to ischemia reperfusion injury, and graft dysfunction subsequent to ongoing inflammatory processes during donor hospitalization. The urokinase values of prostate cancer confined to the organ, with extraprostatic spread and with metastatic disease did not differ and showed no significant difference in comparison with benign prostatic hyperplasia. Clinicians report that chronic cannabis users seem to have symptoms, such as mental confusion and memory problems when entering treatment. A bacteriophage random hexapeptide library was used to define the epitope of a monoclonal anti-keratin antibody. Structure and regulation of a complex locus: the cut gene of Drosophila. Progesterone receptors and oestrogen receptor alpha were present in endometrial stroma and in myometrial smooth muscle cells during whole pregnancy. In an attempt to investigate various pathways that might be involved in estrogen-regulated uterine leiomyoma growth as well as to identify any novel effector genes, microarray studies comparing estrogen-treated uterine leiomyoma cells (UtLM) and normal myometrial cells to untreated cells were performed.

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Dissecting the mechanism of protein disulfide isomerase: catalysis of disulfide bond formation in a model peptide. In view of the known mutagenicity of AP-sites our findings might be of some importance in relation to the mechanisms involved in chromate carcinogenicity. Norepinephrine stimulated cAMP production only one third as much as epinephrine and isoproterenol, but more than double the level of dopamine, dobutamine, and dopexamine. Loss of left lung function was probably compensated by the uninfected right lung, even in a late stage of the disease. False positive values of PAP and PSA in complicated and non-complicated benign prostatic hypertrophy.

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Round-table discussion: Acute bacterial infections in the newborn. Preparation of nucleosides via isopropylidene sugar derivatives. The role of Schwann cell differentiation in perineural invasion of adenoid cystic and mucoepidermoid carcinoma of the salivary glands. During their follow-up period of 2 to 10 years, all 4 patients were well, without evidence of recurrence. Twenty-seven human immunodeficiency virus-infected children aged 1 to 13 years who were treated between 1987 and 1992. Most nasal glands were negative for both AB and periodic acid-Schiff (PAS) staining. Such fractures can be due to head traumas, direct injuries of the tympanic membrane or barotraumas. In case of fever and hypereosinophilia without liver dysfunction, DTIC may be continued together with symptomatic treatment.

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Expression of two mucin genes, MUC2 and MUC5AC, and their protein products (mucins), is modulated in certain disease states. Identification, separation and degradation of mycostatin in hydro-alcoholic drinks in relation to time, reaction of the medium, natural components of wine and sulfurous anhydride. Anti-human CD59 antibodies block this activity of SCIP-1 and in addition, upon binding to intact parasites, render them vulnerable to killing by human and guinea pig C. Paroxysmal MEG activity in obsessive compulsive patients without SSRIs therapy. In order to obtain data about the arterial tissue concentration of type IV and V collagen in diabetic and non-diabetic patients, aortas from 21 patients with diabetes (9 with Type 1 (insulin-dependent) diabetes and 12 with Type 2 (non-insulin-dependent) diabetes), were collected at autopsy together with aortas from groups of sex- and age-matched patients. We probed the conformation of the nucleotide pocket by measuring the solvent accessibility of bound mant-nucleotides.

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A network of antigenic relationships was revealed by reactions between the OLCV mAbs and other whitefly-transmitted geminiviruses from six plant species in 12 countries. cAMP-dependent phosphorylation of a arcoxia etoricoxib 90 mg 29-kDa axonemal polypeptide (p29) increases the swimming speed of permeabilized Paramecium and in vitro translocation velocity of bovine brain microtubules over 22S dynein extracted from Paramecium axonemes. To evaluate the clinical significance of prostatic-specific antigen (PSA) levels in patients with benign prostatic hyperplasia (BPH) complicated by low urinary tract syndrome( LUTS). The etiology of paralytic ileus and acute dilatation of the stomach: studies of plasma 17-hydroxycorticoid levels. Left ventricular volume in thrombolysed patients with acute anterior myocardial infarction: the effect of captopril and xamoterol.

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The consensus opinion was that there are currently insufficient data to justify a preference for either the preincubation or plate-incorporation methodologies as the initial test. At the medullary level, a topographic arrangement of fastigioreticular projection was observed. On the syntactic structure and redundancy distribution of the genetic code. This review identifies issues related to measurement methods used to determine compliance with standards, describes current and future measurement methods and their limitations, and determines the extent to which existing technology can meet short-term and long-term needs for measuring compliance. Evolution of the hooking apparatus of the tube in certain Lepidoptera.

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Moreover, all three fractions were found to increase the expression of IL-1-alpha mRNA while PH-I C showed the most potent activating effect on the expression of IL-1-beta mRNA. Sequences of this fragment are specific for each Rickettsia species. To evaluate the mechanism of spontaneous resolution of foveal detachments and idiopathic macular breaks. A clinical grading scale for intracerebral hemorrhage (ICH), formally ICH score, was recently developed showing to predict 30-day mortality in a simple and reliable manner. Artificial neural networks apply non is xanax ok when breastfeeding -linear statistics to pattern recognition problems. Crystallization and preliminary X-ray diffraction analysis of importin-alpha complexed with NLS peptidomimetics.

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The relation between response rates and reinforcement rates in a multiple schedule. Mitochondrial depletion syndrome (MDS) refers to a heterogeneous group of mitochondrial disorders characterized by a reduction of the mtDNA copy number in affected tissues. To assess the effect of preservation of the bladder neck and other factors on the rate of postoperative urinary continence and cancer control after radical prostatectomy. The goldfish visual pathway displays a remarkable capacity for continued what is an alternative drug to protonix development and plasticity. To assess the prevalence of oral mucosa lesions (OL) in a group of kidney transplant (KT) patients, and analyze possible OL associations with one another and with drugs use and relevant clinical and laboratory variables. However, the role of IFNs in the management of chronic lymphocytic leukaemia and myelofibrosis with myeloid metaplasia is still controversial. In the in vitro experiments, screening for nematocidal activity on the T.

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The SwePep database is a relational database developed using MySql and Java. These results show that chemical (capsaicin) activation of trigeminal nerves leads to vasodilatation of feline arteries in situ. There are multiple clinical, mechanistic, and safety questions requiring answers, and these will be forthcoming only if the design of clinical trials is carefully tailored to answer specific questions. The Moloney leukemia retroviral long terminal repeat trans-activates AP-1-inducible genes and AP-1 transcription factor binding. The aim of the study was to evaluate the effects of endoscopic sinus surgery for chronic maxillary usual dose of xeloda sinusitis in children by investigating ultrastructure element changes in the sinus mucosa and nasal mucociliary clearance before and after operation. Our studies suggest that failure of degranulation may not be a necessary part of this functional leukocyte abnormality. We indeed obtained a number of substrates with the kinetic constants in the desired range. The hydrophobic parameters (log kw) were determined for all tripeptides.

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