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Since the effect of noradrenaline is mediated by cyclic AMP and cyclic AMP-dependent protein kinase, we tested the effect of the purified catalytic subunit of this enzyme on insulin receptors purified by wheat-germ agglutinin chromatography. Twenty-three cats had complete resolution of diarrhea a median of 9 months after onset. Clinical and biochemical study of three patients with tyrosyluria. The attenuated strain of measles viruses, Schwarz, CAM-70, or subacute sclerosing panencephalitis (SSPE) virus of measles viruses, Halle, Mantooth was good interferon inducer, but the virulent strain, Edmonston, Toyoshima induced few amount of interferon or not. Draft and final guidelines were compared to identify changes influenced by the sugar industry and public health organizations.
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A 44-year old man with very severe head trauma had pronounced global aphasia and dyslogia for months. The mechanisms of this neurotoxicity may include decreased neuronal production of autostimulating neurite promoting factors. Characteristics of performing extensive combined pulmonectomies in lung cancer and the surgical results. Clinical implementation of this technique should allow for a reduction of treatment margins, thus sparing more normal tissues and facilitating dose escalation. The aim of the study was to compare the effectiveness of standard information versus a nurse-led tailored intervention designed to promote uptake of colonoscopy screening by siblings of CRC or CAP patients. This hypothesis was supported by an experiment in which entry into M-phase was blocked in fertilized eggs by inhibiting protein synthesis. Sustained virologic response by direct antiviral agents reduces the incidence of hepatocellular carcinoma in patients with HCV infection. In the transhiatal group, excessive bleeding and tumor perforation as a result of blunt dissection each occurred in seven patients (18 percent). The reasons for ordering, usefulness and appropriateness of use were defined prior to analysis.
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The micro-tourniquet method is designed as a substitute and/or supporting technique for obliterating aneurysms that are difficult to operate on using the conventional clipping technique. Patterns of resistance mutations to antiretroviral drugs in extensively treated HIV-1-infected patients with failure of highly active antiretroviral therapy. The method is applied to a simulated data set and the gene tree presented in Verrelli et al. In 47 guinea-pigs, atropine at doses 5 and 10 times higher than the acetylcholine blocking one did not alter the direct bronchial response to histamine (P greater than 0.5). Social class and ischaemic heart disease: use of the male:female ratio to identify possible occupational hazards.
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The evolution of drug-activated nuclear receptors: one ancestral gene diverged into two xenosensor genes in mammals. Nonparametric procedures for simultaneous identification of the minimum effective dose in each of several groups. Cholera toxin B subunit (CTB) mature protein was stably expressed in transgenic tobacco plants under the control of the CaMV 35S promoter and TMV Omega fragment. 11 different, non-cross-reacting antigenic determinants were identified on the vesicular stomatitis virus G protein. Data on age, sex, race, location, clinical appearance, duration, recurrence, and clinical diagnosis are reviewed. Depending on the quantitative ratio of eicosanoids, platelet-activating factor produced various effects on phagocytic functions of heterogeneous macrophage populations.
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Altered ion transport in aortic smooth muscle during deoxycorticosterone acetate hypertension in the rat. No correlation was found between GGT activity and the abilities of different cell lines or GGT-deficient cell strains of TuWi, a human nephroblastoma-derived line high in GGT, to accumulate azaserine. In contrast to gamma-glutamyl transpeptidase and glutathione S-transferase-7.7, whose expression appeared to correlate with the early steps of liver carcinogenesis, Pgp expression was higher in the large hyperplastic nodules and in hepatocellular carcinomas than in the early microscopic lesions. Histopathologically, the tumor was an intraosseous cavernous hemangioma. Three polypeptides of 29,000, 27,000, and about 10,000 molecular weight, determined by IS3411, were identified in minicells. Three neonates were born alive and died within 2 to 12 hours after birth. Antiviral and anticellular activity of human leukocytic and fibroblastic interferons in homo- and heterologous cells. The purpose of this report is to describe the events that occurred immediately before and during the first weeks of the Ebola virus epicemic in the Democratic Republic of the Congo (formerly Zaire) in September and October 1976.
The frequencies of postoperative complications were small in both groups and without any difference between groups. Animals receiving two prior injections of antigen-positive transfected cells and then challenged with an injection of viable ASL-1 cells survived longer than animals in the unprotected control group or in the group receiving immunizations with LM(TK-) cells transfected with plasmid only (p less than 0.01). Hazards of barbiturates in the treatment of asthma, bronchitis, and obstructive pulmonary disease. Complementary hydrolysis of the isopeptides by these digestive enzymes suggests that covalent attachment of oligo(amino acid)s to food proteins may improve their nutritional value. The failure of phosphatidyl choline and sphingomyelin to bind divalent cations may be due to formation of an intramolecular salt between the negatively charged phosphate group and the positively charged nitrogen.
short-term mortality in pts with cardiogenic shock was significantly lower in IABP-treated group, hemodynamic parameters improved after IABP, survivors from cardiogenic shock had higher SVI, SWI, BPd, and lower CVP than non-survivors, patients with VSP and MR had worse prognosis in spite of IABP. Treatment of eosinophils with MalNEt after stimulation had no effect on the NADPH oxidase activity. Vasomotor nerves may lead to flushing as a result of events at both peripheral and central sites. Stepwise molecular evolution of bacterial photosynthetic energy conversion. A river water quality management model for optimising regional wastewater treatment using a genetic algorithm. Passive protection tests using concentrated IgG and IgM antibodies with equivalent neutralization titers showed that IgG antibody gave total protection when given 24 hr before the infection, while it was almost totally ineffective in reducing the mortality when given 2 days or more after infection. Retinoid X Receptor alpha (RXRalpha), a member of the steroid-thyroid hormone receptor super family, is phosphorylated in vitro by protein kinase A (PKA) and this phosphorylation is inhibited in presence of PKA inhibitory peptide. In the rural areas in southern Shaanxi Province, anemia in infants aged 6-12 months is still a serious public health problem.
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All the eyes, except one eye from the dead flight mouse, were examined histologically. We now wanted to see whether similar results could be obtained with lymphoblastoid cell lines (LCLs) and whether such permanent cells are suitable as a model for the investigation of mechanisms involved in mutagen sensitivity. Low vs high dose pre-operative radiation for carcinoma of the larynx remains a valid question. The model, according to the criterion of work rate minimization (both positive and positive plus negative), is able to predict the natural stride frequency as a function of the average progression speed. The effect of chemotherapy combined with recombination mutant human tumor necrosis factor on advanced cancer. Recently, remarkable progress has been made both in the direct differentiation of human ESCs and iPSCs into renal cells and in the generation of tissue- and patient-specific iPSCs, offering a powerful tool to investigate DN mechanisms and to identify the ideal candidate cell for future clinical application. The geographical structure of 15 natural populations of the flat oyster (Ostrea edulis L.) was assessed by single-strand conformation polymorphism (SSCP) of a 313-base-pair (bp) fragment of the mitochondrial 12S-rRNA gene.
A pair of universal primers was designed according to its flanking conservative sequence, and a set of probes specially targeting to eight species of infant pathogenic bacteria, including staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumoniae, Streptococcus faecalis, Hemophilus influenzae, Enterobacter cloacae, Escherichia coli, and Acinetobacter baumannii,according to the variable sequences. The metabolism of 3alpha, 7alpha, 12alpha-trihydorxy-5beta-cholestan-26-oic acid in two siblings with cholestasis due to intrahepatic bile duct anomalies. Hormonal modulation of alpha-fetoprotein gene expression in newborn rat livers. This finding suggests that the antiarrhythmic action of lidocaine in the late stage of myocardial infarction is due to inhibition of the fast inward, sodium current. The fractional clearance of injected radioactive triacylglycerols was less in tumor-bearing rats than in controls, but the turnover (mg/min) was probably not decreased in the tumor-bearing rats because of their expanded plasma pool. Following an intracisternal injection of 1-4 mg 5-HT there was either a fall, or a fall followed by a rise, but in a few experiments the effect consisted mainly of a rise in temperature.4. While these changes seem likely to be artefacts of fixation, their temporal correlation with elastin deposition and their demonstration in other tissue cells engaged in elastin production suggest that the factors responsible for these appearances may be related to elastin synthesis. The innovators had better intraobserver agreement than the other 2 groups. An electromyographic study on the optomotor effect in esotropia under general anaesthesia. Thus, we concluded that TACE is the protease responsible for M-CSFR shedding and down-modulation in mononuclear phagocytes undergoing activation.