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Bresben (Nifedipine)

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Bresben is a calcium-channel blocker. It affects the amount of calcium found in your heart and muscle cells. This relaxes your blood vessels, which can reduce the amount of work the heart has to do. This medicine is used to treat chest pain caused by angina.

Other names for this medication:
Addos, Afeditab, Amarkor, Anpect, Antrolin, Aprical, Atanaal, Calcheck, Calcianta, Cardifen, Cardules, Cisday, Cobalat, Conetrin, Coracten, Cordaflex, Corinfar, Depicor, Depin, Duranifin, Emaberin, Fenidina, Glopir, Herlat, Hexadilat, Macorel, Menoprizin, Milfadin, Nefelid, Nelapine, Nidilat, Nidipine, Nifangin, Nifebene, Nifecap, Nifecard, Nifedel, Nifedicor, Nifedigel, Nifedipin, Nifehexal, Nifelong, Nifical, Nifin, Nipidin, Tensomax, Tensopin, Viscard, Xepalat

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Adalat OROS. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Bresben and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nifedipine dosage information

Side effects

The most common side effects associated with Bresben are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of nifedipine in the elderly. However, elderly patients are more likely to have age-related kidney, liver, or heart problems which may require caution and an adjustment in the dose for patients receiving nifedipine.

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Cortical oscillations in the beta band (13-35 Hz) are known to be modulated by the GABAergic agonist benzodiazepine. Ischemia increases neutrophil retention and worsens acute renal failure: role of oxygen metabolites and ICAM 1. A comparative descriptive study of patients admitted to a high dependency unit after major and non-major surgery. These effects are inhibited by pre-treatment with the antioxidant Vitamin C. Distal arthrogryposis IIB is characterized by contractures of the distal joints (especially of the fingers and toes) and ptosis. The aim of the study was to assess the relationship between risk of gastric cancer and consumption of salt and salt-preserved food. Effect of thyroid-stimulating hormone on ribonucleic acid synthesis in the calf thyroid in vitro in the presence of puromycin. Wallstent endoprostheses have good results and long-term patency.

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Furthermore, inhibition of VEGF function by the treatment with an Flk-1 inhibitor, SU1498, or with the VEGF neutralizing antibody resulted in the reverse of the angiogenic effect on HUVECs. The observed parallel stackings and the intermolecular spacing distances, which were less than the normal van der Waals separation between the isoalloxazine and indole rings and between the isoalloxazine and phenol rings, suggest the existence of charge-transfer interactions in their ground states. Multiple roles for FGF-3 during cranial neural development in the chicken. We critically analysed the RAD in the Yorkshire region for a one-year period. Histologically, the testicular tumor and the lymph node metastases revealed a well-differentiated chondrosarcoma.

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Identification of cytochemical reaction products by scanning x-ray emission microanalysis. Clinically and immunologically stable HIV-infected children had more frequent behavioral problems and lower developmental and cognitive scores than established childhood norms. All randomized and quasi-randomized controlled trials comparing intrarectal with intramuscular or intravenous quinine for treating people with falciparum malaria located through the following sources were included: Cochrane Infectious Diseases Group Specialized Register, CENTRAL, MEDLINE, EMBASE, LILACS and CINAHL. When the liquid medium was supplemented with polygalacturonic acid, only polygalacturonase activity was detected. A cryptococcus infection must be searched by antigen in CSF in case of myelopathy isolated or associated with meningoradiculoencephalomyelopathy, specially in patients with a cellular immunodeficience. Moreover, acetylcholine released from cholinergic neurons also modulates the release of histamine via M1 and/or M3 heteroreceptors.

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Formation of the atrioventricular valves under normal conditions is brought about after the completion of septation and envisages a sequential completion of atrioventricular fissure invagination, myocardium delamination and demuscularization of the folds. In agreement with the accepted model, p53wt delta SS indeed failed to exhibit measurable DNA binding in vitro. Mortality data were obtained from the National Statistics Institute. Suicidal ideations and suicide attempts after starting on aripiprazole, a new antipsychotic drug. Age-related response of the genioglossus muscle EMG-activity to hypoxia in humans. Costimulatory signals, which are required for optimal T-cell activation and for overcoming the induction of anergy, can be provided by the homodimeric T-cell glycoprotein CD28 through its interaction with the counterreceptors B7-1 and B7-2 on antigen-presenting cells. Sequence similarities of MRP-S9 to other members of the ribosomal S9-protein family and the phenotype of disrupted cells are consistent with an essential role of MRP-S9 is assembly and/or function of the 30s subunit of yeast mitochondrial ribosomes. Chronic neuromyotonia as a phenotypic variation associated with a new mutation in the KCNA1 gene.

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CT and MR imaging of desmoid tumors--comparison of two modalities. The correlations of surrogate markers with anti-hepatitis C virus and other disease markers. Reversal of eye preference at reading distance, associated with specific reading disability (dyslexia). Interestingly, the level of GPalpha1 protein is higher in immature organs than in mature organs. Anterior myocardial infarction produces abrupt left ventricular (LV) dysynergy and global systolic dysfunction. The manifold mechanisms of action of APC may give reasons for its application in diseases other than sepsis, which are characterized by endothelial and microcirculatory dysfunction, e.g. In consideration of possible roles for these crystals in articular cartilage, it is concluded that an opportunistic mode of formation, possibly influenced by mechanical stresses, would be most plausible.

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Key categories of opportunity to develop new or expanded nutrition policies and environmental strategies include economic incentives, food assistance and feeding programs, regulations for institutional food service operations, and nutrition services in health care. The results rather support the view that the stomach is important for calcium homeostasis through another mechanism, perhaps involving a hypothetical gastric hormone. In vitro experiments, using human proximal tubular (HK2) cells, revealed that the gene delivery of TIM44 reversed high glucose-induced metabolic and cellular abnormalities such as enhanced reactive oxygen species production, increased ATP contents, alterations in inner membrane potential, increased cell proliferation, and apoptosis. Based on this initial clinical experience we feel that EIT has great potential as a viable clinical aid in imaging the temperature changes imposed during hyperthermia. With the addition of PTX, the expression of ICAM-1 and NF-KappaB p65 was depressed, and the expression of IKappaB-alpha was elevated. These data suggest that supine bottle feeding has a significant effect on middle-ear pressure dynamics, probably caused by the aspiration of milk into the ear. These findings underscore the importance of morning report in general, and the role of attending physicians in particular, in medical education. With chronic antihypertensive treatment, CBF autoregulation may re-adapt towards normal. Prospects for substance differentiation by electron and x-ray micro-methods.

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A retrospective cohort study examined mortality among 1603 patients enrolled at 1 year price of cleocin 100 mg after diagnosis of retinoblastoma during the period 1914-1984. In addition, the relationship of these virulence regulatory systems with other signal transduction mechanisms not involved in pathogenicity is discussed. Since the CDI of plasma HVA is not likely to be confounded by NA activity, this tool may prove useful in disentangling the roles played by the DA and NA systems in schizophrenia. The exceptions to this may represent blocks in this potential regulatory sequence. Effects of methylnaltrexone on morphine-induced inhibition of contraction in isolated guinea-pig ileum and human intestine. Through this visual channel, white spiders on white flowers, and yellow spiders on yellow flowers are virtually undetectable. Specifically, children in the group with a middle score in overall cleanliness acquired severe diarrhea at 2 times the rate as those with a low score (i.e. These changes after temporary pancreatic duct obstruction are very similar to those previously noted during the early stage of diet-and caerulein-induced experimental pancreatitis and suggest colocalization of lysosomal enzymes and digestive enzymes.

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In each case the antibodies to SPf66, CT and lipid A demonstrated an IgG2a predominance. Granulosa cells from women undergoing ovarian stimulation for in vitro fertilization were cultured in defined medium with recombinant human (rh) activin-A and purified porcine follistatin. CT scans showed a small calcified mass in the left temporal lobe adjacent to the sylvian fissure with no enhancement by contrast medium. Results showed that the effect of overlearning on FOK ratings was more detectable in the within-subject design than in the between-subject design. Microbiological contamination of laboratory mice and rats in Korea from 1999 to 2003. The effect of superficial temporal artery-middle cerebral artery anastomosis on regional cerebral blood flow (rCBF) was measured on 31 patients with ischemic cerebrovascular diseases. This study reports on functional morpheme (I, D, and C) production in the spontaneous speech of five pairs of children who have undergone hemispherectomy, matching each pair for etiology and age at symptom onset, surgery, and testing. Advances in transportation technology now permit the accumulation of an export consignment from across an entire country. The glutamate (10 microM)-induced rise in intracellular calcium concentrations was strongly and dose dependently increased and prolonged by simultaneous administration of micromolar concentrations of the reference glutamate transport inhibitors, L-trans-pyrrolidine-2,4-dicarboxylate (PDC) and D- or L-threo-beta-hydroxyaspartate.

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Additionally, an increasing number of monitoring devices are available to assist in the management of patients on bypass. One recombinant clone, designated pOT865, with the smallest DNA insert (4.5 kb) could complement three independent leuB mutations in E. The adenosine agonist PIA but not adenosine itself might be a useful adjunctive therapy. Following a review of the literature and of procedures within the 22 hospitals, criteria for cleaning and disinfection were established and recommendations made. The spinal cord showed edematous and congestive swelling which was intimately related to the coagulation of blood within the epidural veins that contained innumerable fat droplets. There was a similar trend in the lactating ewe.(ABSTRACT TRUNCATED AT 250 WORDS). Gas chromatographic determination of methamphetamine and its metabolite amphetamine in human plasma and urine following conversion to N-propyl derivatives. It was assumed that the epithelial hyperplasia in areas with normal differentiation of crypt cells was an expression of a regenerative reaction. This computational approach was then applied to blood flows through a realistic carotid bifurcation and two Circle of Willis models, one using an idealized geometry and the other using an anatomical data set.

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Networks of globally coupled, noise-activated, bistable elements with connection time delays are considered. Moreover, a transcriptional corepressor N-CoR additively decreased the transcriptional activity of AR with TZF. The conclusions from this study suggest that the Vicia faba chromosomal aberration bioassay is an efficient and reliable short-term bioassay for the rapid screening of chemicals for clastogenicity. FoxN2 and FoxN3 transcripts were found during all developmental stages including early cleavage and tailbud stages. We report in this study our experience with five cases of triple hepatectomies performed for 4 colic cancers and 1 carcinoid cancer. Development of a scalar hospital-specific severity of illness measure. Criteria for the selection of these residues were their accessibility and central position on the CDR surface and the residue character. During the formation of granulation tissue in wound healing a heterogeneity of the expression of endothelial and pericyte markers is found. However, popular accounts of these differences ignore mask configuration. Hearing loss in children with brain tumors treated with cisplatin and carboplatin-based high-dose chemotherapy with autologous bone marrow rescue.

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Since the tumor discussed seems to have originated from a single cell line, the theory that carcinoids develop from neural crest cells which have migrated to embryonic gut endoderm must be regarded with considerable doubt. More cerebral edema developed in animals treated with the platelet inhibitor than in untreated animals, probably because platelet aggregates were inhibited from forming and were not available to plug leaks in the traumatized vessels. Results of the study of sero-agglutination with histamine on latex in dermatology (according to 572 determinations). The authors review some of the commoner indications and pathologies encountered in the context of general practice in which ultrasound has a role. There is no convincing evidence to suggest that the small reduction in plasma potassium levels associated with low dose thiazide and loop diuretic therapy needs to be routinely prevented by the use of potassium-sparing drugs. Although nurses are in an important position in delivering tobacco interventions and provide resources, their participation in consistent delivery of noroxin medicine an intervention is less than desirable. General changes of CCF shape due to image deterioration caused by blur, noise, and lateral sampling (pixel size) were also discussed. Cellular ATP fell during exposure of cells in air to 2-deoxy glucose or to the lactate dehydrogenase inhibitor oxamate.

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The HCEC migration facilitated by IGF-1 was inhibited with the anti-integrin antibody for beta1. Whereas Wnt3a regulates CKIepsilon kinase activity, LRP6 does not, placing CKIepsilon upstream of LRP6. Therefore, every patient is advised to stop smoking at the day before surgery, and not to smoke at all at the day of surgery. The relationship of cerebral seizures to abnormal hemoglobin patterns. In the connective tissue compartment, somatic cells do not contain vimentin, but keratin, as intermediate filament. If an encapsulated hematoma were encountered during an operation, surgeons should pay attention not to overlook the residual capsule encompassing the cavernous angioma or vascular malformation. The formation of surfactant-induced aggregates at intermediate concentrations of the positively charged CTAB is also observed and is explained in the light of electrostatic interactions between the fluorophore and the surfactant. Model estimation was conducted with half the sample, and validation analysis was conducted with the other half. We observed a dramatic and specific overexpression of class II Pgp as a function of the time in culture.

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