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Bolodol (Tramadol)

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Bolodol is a pain medicine similar to an opioid. It acts in the central nervous system (CNS) to relieve pain. Bolodol is used to treat moderate to severe pain in adults. The extended-release form of Bolodol is for around-the-clock treatment of pain. This form of Bolodol is not for use on an as-needed basis for pain.

Other names for this medication:
Adamon, Avdol, Axedol, Bramadol, Cemadol, Contradoc, Cradol, Damadol, Dolocet, Hyperdol, Mandol, Meridol, Nobligan, Nomadol, Nosdol, Opigesic, Orchidol, Ospidol, Ramcet, Sedate, Simol, Taxidol, Tramadol, Tramaflam, Tramataur, Tramdop, Transic, Ultrazac, Vardol, Veeradol

Similar Products:
Lexapro, Allegra, Dulcolax, Cytoxan, Remeron, Claritin, Alprostadil, Levothroid, Colcrys

Also known as: Tramadol


Ultram (tramadol) is a pain medicine similar to an opioid. It acts in the central nervous system (CNS) to relieve pain.

Ultram is used to treat moderate to severe pain in adults.

The extended-release form of tramadol (Ultram ER) is for around-the-clock treatment of pain. Ultram ER is not for use on an as-needed basis for pain.


Follow the directions on your prescription label and read all medication guides. Never use Ultram ER in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to take more of Ultram ER.

Never share Ultram ER with another person, especially someone with a history of drug addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medicine where others cannot get to it. Selling or giving away this medicine is against the law.

Stop taking all other opioid medications when you start taking Ultram ER.

Ultram ER can be taken with or without food, but take it the same way each time.

Swallow the capsule or tablet whole to avoid exposure to a potentially fatal overdose. Do not crush, chew, break, open, or dissolve.

Measure liquid medicine with the supplied syringe or a dose-measuring device (not a kitchen spoon).

Never crush or break a Ultram ER pill to inhale the powder or mix it into a liquid to inject the drug into your vein. This practice has resulted in death.

You may have withdrawal symptoms if you stop using Ultram ER suddenly. Ask your doctor before stopping the medicine.

Store at room temperature away from moisture and heat. Keep track of your medicine. You should be aware if anyone is using it improperly or without a prescription.

Do not keep leftover Ultram ER. Just one dose can cause death in someone using it accidentally or improperly. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, mix the leftover medicine with cat litter or coffee grounds in a sealed plastic bag throw the bag in the trash.

Detailed Ultram ER dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.


Store at room temperature below 25 degrees C (77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Bolodol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Ultram if you are allergic to tramadol, or if you have:

severe asthma or breathing problems; a stomach or bowel obstruction (including paralytic ileus); if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications; or if you have used an MAO inhibitor in the past 14 days (such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine).

Ultram should not be given to a child younger than 12 years old. Ultram ER should not be given to anyone younger than 18 years old.

Do not give Ultram to anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids.

Seizures have occurred in some people taking Ultram. Your seizure risk may be higher if you have ever had:

a head injury, epilepsy or other seizure disorder; drug or alcohol addiction; or a metabolic disorder.

To make sure Ultram is safe for you, tell your doctor if you have ever had:

breathing problems, sleep apnea; liver or kidney disease; urination problems; problems with your gallbladder, pancreas, or thyroid; a stomach disorder; or mental illness, or suicide attempt.

If you use tramadol during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.

Ask a doctor before using tramadol if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.

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The intraosseous pressure in the femur and tibia near the knee and in the internal saphenous vein at knee level was measured in fifty-three patients with suspected knee lesions. The pharmacokinetic profile suggested that the nanoparticles act as a depot in the blood stream during the first hours before being cleared. This article reviews the current state of knowledge regarding the diagnosis, frequency, pathophysiology and management of cramps. the categories were developed from the quality triad proposed by Donabedian: structure, process and outcome. This review may provide new insights and research direction for brain disorders. Idiotype-like determinants on human T lymphocytes alloactivated in mixed lymphocyte culture. Chlorpropamide, a sulfonylurea compound used in the treatment of diabetes mellitus, type II, has been implicated as the cause of untoward reactions involving the hematopoietic, cutaneous, and gastrointestinal systems. Methodology to estimate malaria incidence rates from a commonly occurring form of interval-censored longitudinal parasitological data-specifically, 2-wave panel data-was first proposed 40 years ago based on the theory of continuous-time homogeneous Markov Chains.

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The library was evaluated in vitro, a ninefold potency increase was achieved and the preference for ortho substitution of moderate steric bulk of the fourth, phenyl ring was identified. In contrast to the substitution of these drugs for PTZ, in rats trained to detect the stimulus properties of fentanyl, no substitution of PTZ for the fentanyl stimulus occurred. Evidence for nonporphyrin products as potential inhibitors of uroporphyrinogen decarboxylase. Photocoagulation was successful in obliterating the neovascular tissue. Hippocampal SPR-LI was detected only on the somata and dendrites of GABA-immunopositive interneurons. Here, we describe the details of our sequencing data and the ultra-low input library preparation methodologies.

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This paper aims to answer the question: What competencies do professional nurses need to provide spiritual care?. Hydrostatic pulmonary edema is a common complication of congestive heart failure, resulting in substantial morbidity and mortality. Its general pharmacology resembles the reference agents morphine and pentazocine, but with several differences. However, we selected TBLB instead of SLB because of their general condition and the risk such as prolonged pneumothorax after TBLB. Management of diabetes in French prisons: a cross-sectional study. Contribution to the study of temporary surgical fixation of the total prosthesis. Phosphorylation of residue Y505 in Lck by COOH-terminal Src kinase (Csk), which negatively regulates Lck, is essential for the inhibitory effect of cAMP on zeta chain phosphorylation. What controls the rate and efficiency of charge transfer and charge separation is an important question, as it determines the overall power conversion efficiency (PCE) of these systems.

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The integration patterns of human papillomavirus (HPV) type 16 in the cellular DNA of six cervical carcinoma samples were analyzed by the Southern blot procedure. Semi-automatic analysis of unit channel conductance from voltage ramp records. Obesity and gastro-esophageal acid reflux: physiopathological mechanisms and role of gastric bariatric surgery. These assessments were made within the context of several theoretical models (social cognitive theory and theory of gender and power). Prevalence of sleep apnea syndrome among patients with essential hypertension. An antibody directed against an intracellular, cerebellar IP3 receptor recognizes a protein with a molecular weight similar to the mammalian receptor in the ORNs. Antigen localized within the node can promote the selective entry into the node of T lymphocytes specific for the challenge antigen. Left ventricular mass was assessed by cross-sectional echocardiography in the apical two and four chamber view. Modern insight into the degenerative process of the low back supports this concept.

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Sharp-wave ripple (SWR) events in the hippocampus replay millisecond-timescale patterns of place cell activity related to the past experience of an animal. However, the polycondensation rates in the LB films are considerably slower when compared with those in the monolayers on the water surface kept at the optimum area or surface pressure, because the molecules in the LB films deposited under high compression are packed more closely than the optimum condition. Right ventricular echocardiographic, vectorcardiographic and electrocardiographic study in cor pulmonale. A sympathomimetic administered orally (pseudoephedrine or phenylephrine) may be sufficient, or an antihistamine alone may be helpful in allergic rhinitis. Although OC43 and NCDCV share antigenic determinants, they possessed several different biological properties, including plaque morphology by the infectious centre assay, agglutination of 1-day-old chick erythrocytes and resistance of haemagglutinin to physical and chemical treatments. Immunocytochemistry using polyclonal anti-mDia1 antibody revealed specific immunofluorescence localized to the mitotic spindle. We probe the tissue-level impact of the phenomenon, asking whether layering of cells can magnify the influence of cholesterol, to modulate hypoxia in relation to capillary proximity. Pneumocystis carinii pneumonitis associated with idiopathic immunocyte depletion syndrome.

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These results suggested that this drug would be useful for treatment of shock state. To compare the efficacy and safety of high dose oxytocin in the augmentation of labor. During the 2-year study period, 34 clients in the case-managed and 43 clients in the regular-care group died. Alkylation of DNA therefore appears to occur primarily by a bimolecular reaction not involving free alkyl cations. CTGF mRNA overexpression by parietal epithelial cells preceded the periglomerular appearance of alpha-smooth muscle actin-positive fibroblasts. None of the three subjects with a history of myocardial infarction displayed any ECG abnormalities during the exercise.

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From this complex the terminal DNA fragments can be liberated after pronase treatment. An investigation in man into the relative potency of lignocaine, bupivacaine and etidocaine. Future dietary pattern studies may shed light on the origin of the heterogeneity across populations. This does not mean, however, that the problems posed by unwanted pregnancies and unwanted births have been completely overcome. Among the ligands of type II GPCRs, the calcitonin family peptides including calcitonin, alpha-calcitonin gene-related peptide (alphaCGRP), betaCGRP, adrenomedullin, and amylin are among the best studied hormones, and the founding member, calcitonin, was originally identified and isolated from teleosts. Using enzyme-linked immunosorbent assays and immunoblotting, this study shows that the reduction in expression of OPG after incubation of the dental follicle cells in either CSF-1 or PTHrP also results in a reduction in its secretion. Twenty-five per cent of the patients in the study group, however, had measurements that fell within the normal range. Isradipine in the treatment of peripheral occlusive vascular disease of the lower limbs: a pilot study. This study was undertaken to explain differences in the pathogenesis of periodontitis and peri-implantitis.

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General practice consultation rates for psychiatric disorders in patients aged 65 and over: prospective cohort study. The clinical picture was secondary to a tethered spinal cord syndrome associated to the lipomeningocele. AFP was demonstrated in mononuclear embryonal tumor cells within embryonal carcinoma in a narrow sense, frequently in association with yolk sac tumor. Using immunofluorescence, an affinity-purified anti-annexin-1 polyclonal antibody showed both cytoplasmic and nuclear staining, whereas antibodies against annexins 2, 5 and 6 labelled almost exclusively the cytoplasm of cultured endothelial cells. European register of babies born to mothers with antiphospholipid syndrome. Antibodies directed against the mammalian receptor for low-density lipoprotein showed cross-reactivity with the chicken oocyte VTG receptor, raising the possibility that lipoprotein receptors in birds are structurally related to those in mammalian species. There have been no complications of this approach with its use in over 50 patients undergoing anterior lumbar interbody fusion. Also, our simulation results reveal that the QNT method is effective under a variety of data conditions. To our knowledge, this is the first example of using an enzyme-peptide mimic conjugate to detect a nonpeptide analyte. Electronic data processing in intra-departmental food cost accounting.

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There was a non-significant trend towards more T-lymphocytes in varicose vein. Management strategies include psychological and sexual therapy, pharmacotherapy, and penile vibratory stimulation. Platelet endothelial cell adhesion molecule-1 and vascular endothelial cadherin cooperatively albenza dose regulate fibroblast growth factor-induced modulations of adherens junction functions. Reverse transcriptase-polymerase chain reaction/Southern blotting revealed that both amphioxus TTF-1 and TPO genes are expressed mainly in the adult endostyle. Allodynia in rats infected with varicella zoster virus--a small animal model for post-herpetic neuralgia.

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The cytochemical and isoserological methods employed showed some structural disturbances in the state of erythrocyte, glycocalyx and its modification in the course of treatment. These properties show that the intermediate is a normal on-pathway form that contains, in addition, adventitious misfolding errors that transiently block its forward progress. Bone changes in the course of a gastrointestinal malabsorption syndrome. Visceral oxygen delivery was 4.8-fold greater compared with controls. Effects of local application of antiserum on the development of tuberculous lesions in the lung of the guinea pig.

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A feature of primary paravesical tumor, which is derived from connective tissue, is that it manifests no symptoms or signs until the tumor attains considerable size. The donor twin had no visible bladder, but the amniotic fluid volume had normalized after amniocentesis. Spectrophotometric method of determining the concentration of phenols in the blood. Frequency and resolution dependence of the anisotropic impedance estimation in cortical bone using time-resolved scanning acoustic microscopy. G6PDH and IDH activity in the kidney is influenced to a much lower viramune medication degree by food intake. Acceleration of the hemoglobin switch in cultures in neonate erythroid precursors by adult cells.

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Glutamic acid diethyl ester (GDEE) (400 micrograms), injected into the dorsal hippocampus, had qualitative effects similar to those obtained with scopolamine, but, quantitatively, they were less pronounced. Placement of Denver PVS for the treatment of malignant ascites appears to be a safe and useful procedure. We have proposed a structural model of beta-AR which is similar to that elucidated for rhodopsin. The results obtained were as follows: After white noise exposure of 95 dB (A), the locomotor activities of rat increased. Cognitive Behavioral Therapy for Insomnia in Breast Cancer Survivors: A Review of the Literature. Here, we developed a biotechnology method for the rapid screening of microbial ester biosynthesis.

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In this article, we address two issues regarding the admixture approach. All calcified atherosclerotic plaques contained Ca and almost all Br and Sr. However, modification of pH, redox potential, electrical conductivity, dissolved oxygen and alkalinity correlated with the concentrations of heavy is there penicillin in flagyl metals. To study the main prognostic factors and significance of facial nerve decompression of facial paralysis in temporal bone fracture, the main relative prognostic factors of 64 patients with facial paralysis were analyzed. Omentopexy is the usual countermeasure to prevent or overcome the ischemia of the airway but this is frequently not sufficient.

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In summary, we found that RSV Gag shows no preference for membrane order, while proteins with reported membrane-penetrating domains show preference for disordered membranes. Erratum to: Criteria for ultrasound diagnosis of deep venous thrombosis of lower extremities. Both the flagellar beat frequency and the axonemal ATPase activity are nearly wild-type. T-cell production of eosinophil-active cytokines (IL-5, IL-3, GM-CSF) is thought to be fundamental to asthma pathogenesis. A conventional diet was administered at random to 21 patients, and a commercial enteral diet to the remaining 28. Coupled with a suitable virus concentration and purification system, ICC/strand-specific RT-PCR will provide a novel and rapid method for detection of infectious HAV in clinical, environmental and food samples. Maternal smoking and caffeine use during pregnancy were not significantly related to infant size at 8 months, although nicotine use had been highly related to the birth size in this sample. These experiments show that the protective effect of estradiol and IGF-I against apoptosis depends on unperturbed progression through the cell cycle. In addition, the C-terminal residues of the protein, some of which are disordered in the absence of DNA, appear to contribute to the binding. Effect of digoxin, strophanthin and isolanid on oxygen absorption, oxidative phosphorylation and the amount of cytochromes in the myocardial mitochondria and their ATPase activity.

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We conclude that 17beta-estradiol and progesterone do not influence the cytokine-production capacity of LPS-stimulated monocytes in humans. The Mr approximately equal to 115,000 protein is lexapro a psychotropic medication was released from the membranes and did not react with an antibody to the carboxyl-terminal (cytoplasmic) domain of the apoB,E(LDL) receptors. Mechanisms of onset and termination of abnormal cardiac rhythm studied by constant monitoring. The simultaneous analysis of carbon monoxide and suspended particulate matter produced by cigarette smoking. The asymptotic relative proportions of individuals of the different types is studied in the neutral case. There was recurrence in only two patients, both treated with cecopexy. Sensitive assays were used to detect soluble paraprotein either in serum or in supernatants from cultures of peripheral blood mononuclear cells (PBMC) and bone marrow cells. Increasing numbers of young people have risk factors for type 2 diabetes, particularly obesity, indicating the need for effective type 2 diabetes prevention strategies. By taking full advantage of all the information presented in the course of training in the differentiator, we demonstrate a powerful adaptive system capable of learning continuously changing patterns. The uppermost layer consists of parallel tubules structurally similar to those of the axoneme.

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A progressive atrophy of the hair bulbs and follicles is the basis for the absence of hairs after the first pelage. No evidence exists that cases of vCJD are related to the use of vaccines, and no cases of vCJD have been reported in the United States. Recognition of a tetranucleotide loop of signal recognition particle RNA by protein SRP19. These results address an outstanding difference in the serological interpretation of H-2, where these types of public reactions have been well established, from HLA, where they have been poorly characterized. Observations of the ranges of flexion of the lumbar interbody joints under standardized loading have been made before and after isolated floating fusions were performed. This work presents derivation, implementation, and the first applications of the restricted-unrestricted approach based on restricted Kohn-Sham formalism for evaluation of hyperfine coupling constants. New technologies have led to tremendous progress in understanding what today we call bipolar disorders, whose clinical diagnosis has been refined continuously since Kraepelin first described them.

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A pars plana approach allows insertion of the vitrophage into the eye with minimal surgical manipulation. These 2 groups of patients with VATS (V) or without VATS (O) were studied for their progress in hospital and the final outcome. Multifunctional transcription factor (TF) gene EWS/EWSR1 is involved in various cellular processes such as transcription regulation, noncoding RNA regulation, splicing regulation, genotoxic stress response, and cancer generation. During osteogenesis, mesenchymal tissues function to form fibrous matrix which changes into bone by ossification. We show here that, on the basis of molecular weight measurements and of amino acid composition determinations, svp-1 and RSV-V are indeed the same protein. This effect of insulin utilizes the FOXO-dependent regulation of the thor gene, which encodes the Drosophila homologue of the eif-4e binding protein (4eBP). The reagents employed do not require plasma congenitally deficient in factor VIII. After the 10 day treatment all the mice were sacrificed, and the cecal contents were collected for quantitative analysis of the intestinal bacterial flora. p53 is a 53-kDa nuclear protein that is associated with malignant transformation in several tumor model systems.

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High levels of spectacle independence with low levels of photic phenomenon were achieved, resulting in excellent patient satisfaction. Unanesthetized animals were bled continuously through jugular vein cannulae for an initial 1 1/2 h control period. The correlation between in vitro binding in the presence of 100 mM sodium and analgesic potency was not as good AS THAT as that found in the absence of sodium. The biometric analysis conducted on the parental, F1 hybrid and backcross populations indicates very clearly that the effects of morphine are genetically determined. However, owing to their structural complexity and some redundancy in terms of structures that elicit a function, the therapeutic potential of complex glycans has not been well exploited, with a few notable exceptions. Furthermore, elimination of the 26- and 27-carbons decreases biological activity by 100-fold. If a positive correlation between the in vitro and in vivo findings would exist, these tests can act as a pre-screening before new reagents are tested in vivo.

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We review how the SVZ is perturbed following various animal TBI models with regards to cell proliferation, emigration, survival, and differentiation, and we review specific molecules involved in these processes. Analytical characterization of urinary proteins by sodium dodecyl sulphate-polyacrylamide gel electrophoresis in renal disease. Tandem repeats are associated with disease genes, play an important role in evolution and are important in genomic organization and function. Spondylosis deformans (SD) must be considered as an important differential diagnosis which in humans, unlike DISH, is always accompanied by degenerative disc disease. Moreover, the suppression of CO2 estimates by carvone was reflected in a corresponding suppression of the CSERP amplitudes. Bathydraco marri Norman is a cold-adapted Antarctic teleost (Family: Bathydraconidae), living preferably at depths between 400 and 1200 m. In most of the cases fetal loss is due to habitual abortions, intrauterine death and premature labors.

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