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Biotrim (Trimethoprim)

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Biotrim is an effective combination antibiotic; however, it may not be suitable for those with kidney or liver disease or folate deficiency. The risk of side effects may be higher in the elderly.

Other names for this medication:
Adrenol, Bacterol, Bactipront, Bactoprim, Bactramin, Bactrimel, Baktar, Balsoprim, Biseptrin, Broncoflam, Cotrimoxazol, Cotrix, Epitrim, Escoprim, Eusaprim, Exazol, Groprim, Novotrim, Noxaprim, Octrim, Onetrim, Primadex, Primazole, Septra, Sulbron, Sulmetrim, Sulprim, Suprasulf, Supreme, Sutrim, Theraprim, Trimecor, Trimoks, Trimosazol, Trimoxsul, Vanasulf

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Also known as: Trimethoprim


This medication is a combination of two antibiotics: sulfamethoxazole and trimethoprim. It is used to treat a wide variety of bacterial infections (such as middle ear, urine, respiratory, and intestinal infections). It is also used to prevent and treat a certain type of pneumonia (pneumocystis-type). This medication should not be used in children less than 2 months of age due to the risk of serious side effects. This medication treats only certain types of infections. It will not work for viral infections (such as flu). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.


Take Bactrim exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.

Drink plenty of fluids to prevent kidney stones while you are using this medicine.

Sulfamethoxazole and trimethoprim doses are based on weight in children. Use only the recommended dose when giving this medicine to a child.

Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. This medicine will not treat a viral infection such as the flu or a common cold.

You may need frequent medical tests.

This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using Bactrim.

Store at room temperature away from moisture, heat, and light.

Detailed Bactrim dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include loss of appetite, vomiting, fever, blood in your urine, yellowing of your skin or eyes, confusion, or loss of consciousness.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Side effects

The most common side effects associated with Biotrim are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Generic Biotrim if you are allergic to Generic Biotrim components. Do not take Generic Biotrim if you're pregnant or you plan to have a baby, or you are a nursing mother. Generic Biotrim can harm your baby. Do not take Generic Biotrim if you have anemia. Generic Biotrim can't be given to children younger than 2 months old. Avoid exposure to sunlight, sunlamps, or tanning beds while taking Generic Biotrim. Be careful with Generic Biotrim if you have kidney or liver disease, folic acid deficiency, asthma or severe allergies, AIDS, glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency); if you are malnourished. Be careful with Generic Biotrim if you take seizure medication such as phenytoin (Dilantin); diuretic (water pill); blood thinner such as warfarin (Coumadin); methotrexate (Trexall, Rheumatrex); methotrexate (Trexall, Rheumatrex); or an ACE inhibitor such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace) or trandolapril (Mavik). It can be dangerous to stop Generic Biotrim taking suddenly.

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The introduction of procedures from other industries has brought a new level of standardization and quality control to the fabrication of prostheses. In the short-term infusion group, spasticity of the hindlimbs developed during infusion at 0.5 nmol/h or more of AMPA, tremors at 50 nmol/h or more, and flaccidity at 65 nmol/h or more. Abstracts of the 46th Spring Meeting of the German Society for Experimental and Clinical Pharmacology and Toxicology. EST libraries are used in various biological studies, from microarray experiments to proteomic and genetic screens. Drug Insight: from disturbed motility to disordered movement--a review of the clinical benefits and medicolegal risks of metoclopramide. These lesions seem to be likely focal fatty infiltration or perfusion defect due to venous supply variation or both. In the proposed algorithm, the LR frames are adaptively weighted according to their reliability and the regularization parameter is simultaneously estimated. IL10 and IL12B polymorphisms each influence IL-12p70 secretion by dendritic cells in response to LPS.

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Prevention of adhesion formation/reformation with the Gore-Tex Surgical Membrane. Then, hemodynamic studies were performed using radioactive microspheres. A medical practice without any clinical examination of the patient is contrary to medical ethics. Those who develop IDDM may exhibit less genetic heterogeneity than their ICA-positive or ICA-negative relatives. Doppler ultrasound and angiography of the vasculature of the liver in children after orthotopic liver transplantation: a prospective study. The method of thread-dragging through fistula in treating simple low and high anorectal fistula can shorten the course of the disease, save the hospitalization expenses, improve the life quality of the patients, and protect the anal sphincter function. Here, we address the question whether the ectopic co-expression of ovule identity proteins is sufficient to induce the homeotic conversion of vegetative leaves into carpel-like structures bearing ovules. No case of coarse renal scarring due to recurrent urinary tract infections was reported. In primary human diffuse astrocytomas, PAX5 expression inversely correlated with p53 expression. (a) A retrospective case-control study and (b) a prospective study of consecutive liver transplant recipients.

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Forensic experts have focused more on the psychological profile of a serial killer rather than on the pronounced effects on the community at large. Lectin-gold labeling shows that these cross-links contain sialic acid residues. Among group C isolates only two of the six amplicons, designated as A and G, were effective in discriminating ET15 from non-ET15 isolates. Inspection of the overlap regions between ORF1a and ORF1b of the SARS-CoV genome revealed that, similar to all coronaviruses, a programmed -1 ribosomal frameshift could be used by the virus to produce a fusion protein. Four phases in the folding were detected by rapid-reaction kinetic measurements of the intrinsic fluorescence of both wild type and barnase mutants. More than half of the patients whose response could be assessed had some symptomatic relief from the radiotherapy treatment. Strategies for both cost saving and effective implementation are however required for mass cervical screening in developing countries. Our results show in vivo stability for the three methods during a period extending from 3 to 41 months.

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GAP31 (gelonium anti-HIV protein of 31 kDa) is an anti-HIV protein which we have identified and purified from a medicinal plant, Gelonium multiflorum. Direct sequencing of the CAPN3 gene revealed compound heterozygous state for two mutations previously described in association with limb girdle muscular dystrophy, proving pathogenicity. A panel of monoclonal and polyconal antibodies to cytokeratins, vimentin, and collagen was used to label cells and collagen types I, III, and IV. Interestingly, many imprinted genes appear to control cell proliferation and growth in both groups of organisms although imprinting in plants may also be involved in the cellular differentiation of the two pairs of gametes involved in double fertilization. Special attention is paid to how chronic invaginations, as a result of their varied, unremarkable symptomatology, often involve mistaken or late diagnosis. If necessary, at a second stage plastic reconstructive operations are performed with a view to improve the biomechanics of the foot. Preparation goes a long way in overcoming some of the obstacles to seamless patient care. The impact of early use of prescription contraceptives on reducing premarital teenage pregnancies. This study tests the hypothesis that the activators of peroxisome proliferator-activated receptors (PPARs) and 9-cis-retinoic acid receptor (RXR) regulate human semaphorin 6B (Sema6B) gene expression.

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On the role of hereditary factors in the pathogenesis of peptic ulcer of the stomach and duodenum. Inferences are performed by using a stochastic simulation algorithm called Gibbs sampling. Two ORFs present high similarity to known proteins: NO345 with the hexose transporter family, and NO351 with the yeast chorismate mutase/prephenate dehydratase enzyme encoded by PHA2. Vasodilating actions of cromakalim in resting and contracting states of carotid arteries from spontaneously hypertensive rats. It is important that nurses work to promote the health of all patients, including those with apparent terminal diagnoses. Its reactivity was similar to but weaker than that of two other well-characterized mAbs to DAF, IA10 (seeing an epitope within SCR1) and 1C6 (seeing an epitope within SCR3). While this technique is widely used to visualize white matter pathways, the associated uncertainty in fiber orientation and artifacts have, to date, not been visualized in conjunction with the trajectory data. The UHFER of rat thymocytes caused similar changes in Acridine orange binding to cellular DNA, light scatter parameters of thymocytes, their own UV fluorescence and partition in two phase systems as X irradiation.

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The authors have considered external irradiation, inhalation and ingestion of dust and inhalation of radon and radon daughters as the main occupational exposure routes. Isoaspartyl dipeptidase (IAD) is a member of the amidohydrolase superfamily and catalyzes the hydrolytic cleavage of beta-aspartyl dipeptides. We show here that when the tobacco Tnt1 retrotransposon is expressed, its RNA is not a unique sequence but a population of different but closely related sequences. Most tumors are quite large by presentation and are easily detected by imaging studies. The team together sets standards, which provide targets appropriate to the context and towards which the service should aim. Ornithine decarboxylase gene expression is aberrantly regulated via the cAMP signal transduction pathway in malignant H-ras transformed cell lines. Joint stress of chlorimuron-ethyl and cadmium on wheat Triticum aestivum at biochemical levels.

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Correlation of DNA ploidy and S-phase fraction with chemotherapeutic response and survival in a randomized study of disseminated malignant melanoma. In search of the socio-cultural factors contributing to the development of neurotic reactions in Persian women, the author has examined the records of two hundred and eighty five (285) patients from his private practice in Tehran. In addition, PROBE was performed in either the occipital cortex (gray matter) or the parietal cortex (white matter) or, more rarely, within the confines of a focal lesion identified on MRI, using a GE Signa 1.5 T whole-body scanner, in 112 patients undergoing routine brain MRI. Age-dependent decrease in endothelium-dependent hyperpolarizations to endothelin-3 in the rat mesenteric artery. Results have been as good as for transplantation from cadaveric donors. Helicobacter pylori cag-type IV secretion system facilitates corpus colonization to induce precancerous conditions in Mongolian gerbils. Ten consecutive dogs were studied to investigate the effects of brain death on hemodynamic, metabolic, and hormonal function. Body surface distribution of significant changes in QRST time-integral values after radiofrequency catheter ablation in patients with Wolff-Parkinson-White syndrome. When the oscillation is stopped, the two fluids remain separated by a very thin air film, which drains very slowly (approximately 30 min).

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The gene expression signature in PVNS is similar to that of activated macrophages and is consistent with the local destructive course of the disease. The protein activated by GH is antigenically similar to p91, a protein common to several transcription complexes that are activated by interferons and other cytokines. This case documents the progression of untreated vulvar intraepithelial neoplasia to invasion in a young woman over a four and a half year period. Subjective reactions to rapid and normal pace adversive smoking. The area under the curve decreased significantly at steady state, regardless of renal function. To our knowledge, symptomatic radiation-induced valvular dysfunction in the aortic position has been reported infrequently, with only eleven reported cases.

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Nerve growth factor amplifies cyclic AMP production in the HT4 neuronal cell line. Block of nicotinic acetylcholine-activated channels of cultured mouse myotubes by isoflurane. These results suggest that the clinical application of antiandrogen therapy for human hepatocellular carcinoma might be possible in the future. A further experimental study of a response-interference versus a drive-facilitation theory of the effect of anxiety upon learning. Excision of ultraviolet-induced photoproducts of 5-methylcytosine from DNA.

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Using Southern blotting, polymerase chain reaction/single-strand conformation polymorphism (PCR-SSCP) analysis and direct sequencing, no germline mutations were found. It would therefore be expected that loss of the endothelium during arterial injury would lead to vasospasm and thrombosis but instead, the neointima formed after injury has a nonthrombogenic surface and a maintained vascular patency. Despite previous suggestions that the legal standards might form a hierarchy of rigorousness, the data did not support this hypothesis. In addition, we developed a heterologous double antibody sandwich assay able to identify circulating CL-5/5A antigens in pre-treatment sera of patients with SCLC. The cytokine milieu at the implantation site plays a role in human pregnancy. Organochlorine pesticides in agricultural soil and vegetables from Tianjin, China. A girl with green complexion and iron deficiency: chlorosis revisited. The results of our study have shown that routine ureteral stent insertion has no impact on the rate of vesicoureteral leakage or obstruction in live-donor renal transplantation, whereas it is significantly associated with an increased incidence of urinary tract infection. vitamin E and selenium have been observed to enhance the functions of bovine mammary gland macrophages and peripheral blood lymphocytes.

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Improved gene delivery to intestinal mucosa by adenoviral vectors bearing subgroup B and d fibers. Characterization of constitutive human serum amyloid A protein (SAA4) as an apolipoprotein. Further, a resolution of nearly 1000 can be obtained for the fragment products, due to the cooling effects of the buffer gas in the trap before analysis by the reTOF. Multivariate models were used to assess the effects of age and comorbidity (as measured by the International Classification of Diseases, Ninth Edition, codes recorded on Medicare claims) on initial treatment approach while adjusting for stage of disease, race, residential location, marital status, and year of diagnosis. However, orangutan sequences group together in both kinds of C4d sequence dendrograms and seem to have arisen from an ancestor different from that of chimpanzee, gorilla and man C4d sequences. A multitude of in vivo variables can influence systemic drug absorption after intake of an oral formulation. In the hippocampal formation, both Kv1.1 and Lgi1 are coassembled with Kv1.4 and Kvbeta1 in axonal terminals. We investigated the effects of intraplantar ( administration of L-arginine and NG-nitro-L-arginine methyl ester (L-NAME) on formalin-induced behavioural nociception in the mouse. The children had been exposed in utero to a mean total dose of 186.6 mg DEX.

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Three-dimensional Fourier synthesis of horse oxyhaemoglobin at 2.8 A remeron 15 mg uses resolution: the atomic model. The intracellular signal was observed by pre-treatment of the cells with antioxidant pyrrolidine dithiocarbamate, NADPH oxidase inhibitor apocynin or p38 phosphorylation inhibitor SB203580. The predominant techniques rely on either physical separation of the T cell (binding to erythrocytes, lectins, centrifugation) or reaction with monoclonal antibodies (immunomagnetic, panning, complement-mediated cytotoxicity, immunotoxins). Polymerase chain reactions carried out using this primer pair and untreated cells of all strains of C. In keeping with theoretical expectations theresults showed that when the different inverted and reversed feedback conditions could be performed, the response to the inverted feedback condition wasthe poorest, while that to the reversed condition was the most effective. Transient ipsilateral innervation of the cerebellum by developing olivocerebellar neurons.

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Crystal form I grows in space group P3(1) or P3(2), whereas crystal form II grows in space group C222(1). B cell antigen receptor is composed of immunoglobulin and associated MB-1 and B29. These low-shear vessels also make three-dimensional cellular co-cultures possible and thus allow to study the gravisensitivity of radioresponse in a context that better mimics cell-to-cell communication and hence in vivo cellular behavior. The method was applied to incidence and mortality data for selected malignant neoplasms in 26 administrative health areas in Sweden. Information and health education are important aspects of holistic care.

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41 postpartum (8 weeks) patients attending a family planning clinic had Lippes Loop D insertion. Modulation of the activity and assessment of the receptor selectivity in a series of new RGD-containing peptides. Molecular species of circulating interferon in mice injected with Newcastle disease virus. Synthesis of 2-imidazolidinylidene propanedinitrile derivatives as stimulators of gastrointestinal motility--II. This article describes a simple, quick, and inexpensive solution to a difficult problem.

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On the optimality of the genetic code, with the consideration of coevolution theory by comparison of prominent cost measure matrices. The biochemical, morphological, and pathogenic characteristics of this microorganism are discussed. A 5MHz linear-scanner and a 3.5 MHz convex-scanner (76 degrees) turned out to be suitable. Here we review and discuss traditional strategies and novel approaches based on tandem mass spectrometry for the identification of the key active site residues in glycosidases. In the three patients who had tuberculous spondylitis, contrast MR images showed geographic and/or ring-like enhancement of the vertebral body. Diagnosis depends on light-microscopic detection of oocysts in stool smears stained with acid-fast stains. We also found that the absolute difference in age between parent and adolescent significantly smaller in the at-risk group as compared to the control group. Clinical and phonocardiographical analysis of systolic murmurs in arteriosclerotic cardiopathy. Transfection of the fucosyltransferases Fuc-TIII, Fuc-TIV, and Fuc-TV mediates cell surface expression of sialyl-Le(x) in many cell lines.

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Toward an increase in reading efficiency utilizing specific suggestions: a preliminary approach. Responses of maxillary chemoreceptors in the larva of the silkworm, Bombyx mori, to stimulation by carbohydrates. Domestic and international arrivals of NOBOB (no ballast on board) vessels to lower Chesapeake Bay. Invasive hyphal growth: an F-actin depleted zone is associated with invasive hyphae of the oomycetes Achlya bisexualis and Phytophthora cinnamomi. As reproductive factors, particularly parity, are risk factors for ovarian cancer, we investigated possible relationships between reproductive history and survival from ovarian cancer. The initial CT and MR features of pilocytic astrocytoma are unreliable for predicting which lesions will behave in a zithromax 250 mg side effects more aggressive manner clinically and have a poor prognosis.

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Suppression of alcohol drinking with brain aldehyde dehydrogenase inhibition. In the first phase of a collaborative study by the International Programme on Chemical Safety (IPCS), four coded chemicals, i.e. This combined analysis suggests that terazosin can be safely administered to both normotensive and hypertensive patients with symptomatic BPH. The comparison in terms of early complications of a new technique and percutaneous method for the placement of CAPD catheters. Since the wall of the middle cerebral artery aneurysm showed granulomatous changes with infiltration of many inflammatory cells, the aneurysmal enlargement is considered to have resulted from chronic inflammation of the wall.

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The efficacy of simultaneous operation of aortic valve and pacemaker implantation was emphasized. Others respond to only one of the two modalities, but show greatly enhanced or depressed responses when stimulated simultaneously in the second modality. Research is needed to identify other factors that may impact on quality of life, and to establish the extent to which inpatient and home-based care meets the needs of both the patient with terminal cancer and their family. Actinic reticuloid is a polymorphous dermatosis resulting from a photosensitivity to long wavelength ultraviolet light and occasionally also to visible light, often with clinical and histological resemblance to lymphoma. Increasing evidence suggests that somatosensory information is modulated cortically for task-specific sensory inflow: Several studies report short-term adaptation of representational maps in primary somatosensory cortex (SI) due to attention or induced by task-related motor activity such as handwriting. Moreover, treatment of cultured fibroblasts with antibodies that inhibit fibronectin assembly significantly inhibit fibulin-1 incorporation into the matrix.

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A presumptive Y-autosome translocation in a boy with congenital malformations. We used a graded bioassay described by logistic function and executed by computer program (ALLFIT) to evaluate changes in infarct volume after increasing durations of ischemia maxolon dose children . For many applications, not all of k-space needs to be updated each frame, and nonuniform k-space sampling can be used to exploit this rapid imaging strategy by allowing variable update rates for different spatial frequencies. Oestradiol administration increased IP3 level at 1 and 6 h after treatment, whereas activated MAPK p44/42 level was unchanged. The present model of established infection of normal C57BL/6 mice is more relevant than the model of early infection for a stringent evaluation of drugs. However, there is no online tool to facilitate this interpretation, for example, by automatically attaching taxonomic information to the nodes of a tree, or by interactively colouring the branches of a tree according to any combination of taxonomic divisions. These results indicate that the decrease of superoxide dismutase may be involved in the increase of oxidative stress in brain of SAMP8 at younger stages. Current use of Enteryx requires fluoroscopy for accurate placement into the deep esophageal wall (ie, the deep submucosa or muscularis propria). The evidence that allergens produce the cutaneous changes in atopic dermatitis is flimsy, and neurodermatitis would be a more appropriate term since the entity falls into that pattern of skin changes.

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Transforming growth factor-beta: a down-regulator does drinking alcohol affect lexapro of the parathyroid hormone-related protein receptor in renal epithelial cells. Based on (1) the in vivo response expected on quantitative BoNT-antitoxin systems and (2) the actual and the hypothetical antigenic makeup of BoNT subtypes, a comprehensive method for BoNTs typing is proposed. To critically examine the expression of aFGF by RPE cells, we studied the density dependence of steady-state levels of mRNA and protein expression in vitro. Statistical analyses of the two groups of patients showed a significant correlation between differentiation and age above 40 years, extrathyroid tumor extension and low ratio of regional nodal involvement at the onset of disease. The TFN- mutant containing the exp10-phoA fusion produced activator, a small extracellular polypeptide that induces competence, and the expression of rec was induced in response to activator. Junction of cancerous epithelium and stroma in the uterine cervix: electron microscope studies. Close evolutionary relatedness among functionally distantly related members of the (alpha/beta)8-barrel glycosyl hydrolases suggested by the similarity of their fifth conserved sequence region. An outbreak of tuberculosis involving foreign workers from South America.

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