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Biostatik (Roxithromycin)
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Biostatik

Biostatik is indicated for the treatment of the following mild to moderately severe infections in children caused by or likely to be caused by susceptible micro-organisms: acute pharyngitis, acute tonsillitis and impetigo.

Other names for this medication:
Acevor, Asmetic, Assoral, Azuril, Bazuctril, Biaxsig, Bicofen, Biostatik, Cadithro, Delos, Erybros, Klomicina, Ladlid, Macrolid, Macrosil, Makrodex, Monobac, Odonticina, Pedrox, Ramivan, Redotrin, Remora, Renicin, Ritosin, Rokithrid, Roksolit, Romyk, Roxacine, Roxithromycine, Roxithromycinum, Roxitromicina, Rulid

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Terramycin, Benemid, Duricef, Tricor, Panadol, Micardis, Sovaldi, Albenza, Motrin

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Also known as: Roxithromycin

Description

Generic Biostatik belongs to macrolides group of antibiotics which are prescribed for treating serious bacterial infections such as acute pharyngitis (sore throat and discomfort when swallowing), tonsillitis, sinusitis, acute bronchitis (infection of the bronchi causing coughing), pneumonia (lung infection characterised by fever, malaise, headache), skin and soft tissue infections, non gonoccocal urethritis, impetigo (bacterial infection causing sores on the skin). It acts on the bacteria which causes the above mention bacterial infections caused by the bacteria. It kills completely or slows the growth of these sensitive bacteria in our body. Generic name of Generic Biostatik is Roxithromycin. Biostatik is also known as Roxithromycin, Roximycin, Biaxsig, Roxar, Surlid. Brand name of Generic Biostatik is Biostatik.

Dosage

Take Generic Biostatik by mouth with food. If you have trouble swallowing the tablet whole, it may be crushed or chewed with a little water. Swallow Generic Biostatik tablets whole with a glass of water. Generic Biostatik should be taken at least 15 minutes before food or on an empty stomach (i.e. more than 3 hours after a meal). Generic Biostatik works best if you take it on an empty stomach. For treating bacterial infections, Generic Biostatik is usually taken for 5 to 10 days. If you want to achieve most effective results do not stop taking Generic Biostatik suddenly.

Overdose

Immediately telephone your doctor or pharmacist. Do this even if there are no signs of discomfort or poisoning.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Do not store in the bathroom. Keep in a tight, light-resistant container. Keep out of the reach of children.

Side effects

The most common side effects associated with Biostatik are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

The safety of roxithromycin has not been demonstrated in patients with impaired hepatic or renal function. Caution should be exercised if roxithromycin is administered to patients with impaired hepatic or renal function. If administered to patients with severe impaired hepatic function (eg. hepatic cirrhosis with jaundice and/or ascites), consideration should be given to reducing the daily dosage to half the usual dosage.

Prolonged or repeated use of antibiotics including roxithromycin may result in superinfection by resistant organisms. In the event of superinfection, roxithromycin should be discontinued and appropriate therapy instituted.

When indicated, incision, drainage or other appropriate surgical procedures should be performed in conjunction with antibiotic therapy.

Antibiotic associated pseudomembranous colitis has been reported with many antibiotics. A toxin produced by Clostridium difficile appears to be the primary cause. The severity of the colitis may range from mild to life threatening. It is important to consider this diagnosis in patients who develop diarrhoea or colitis in association with antibiotic use (this may occur up to several weeks after cessation of antibiotic therapy). Mild cases usually respond to drug discontinuation alone. However, in moderate to severe cases, appropriate therapy with a suitable oral antibacterial agent effective against Clostridium difficile should be considered. Fluids, electrolytes and protein replacement therapy should be provided when indicated.

Roxithromycin, like erythromycin, has been shown in vitro to elicit a concentration - dependent lengthening in cardiac action potential duration. Such an effect is manifested only at supra – therapeutic concentrations. Accordingly, the recommended doses should not be exceeded. In certain conditions macrolides, including roxithromycin, have the potential to prolong the QT interval. Therefore roxithromycin should be used with caution in patients with congenital prolongation of the QT interval, with ongoing proarrhythmic conditions (ie uncorrected hypokalemia or hypomagnesaemia, clinically significant bradycardia), and in patients receiving Class IA and III antiarrhythmic agents.

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Cloning of the restriction-modification genes of Bacillus centrosporus in Escherichia coli. The association between schizophrenia and being unmarried was higher in urban than in rural areas. The duration of symptoms at the time of last examination varied from 5 to 58 years. Using the Affymetrix Human Gene 1.0 ST platform, microarray analysis revealed that an association between EHD1 and epithelial-mesenchymal transition (EMT), supported by downregulation of mesenchymal markers and upregulation of epithelial markers following knockdown of EHD1 in cell lines. Though at a low rate, caldariellaquinone, a unique and sole benzothiophenequinone in the genus Sulfolobus, was also reduced by the enzyme, suggesting that the enzyme is a possible member of the respiratory chain of the thermoacidophilic archaebacterium. The scans were superimposed, radial measurements calculated, and the changes illustrated by two separate colour scales. Time-series analysis of the effects of barbiturates on the electroencephalograms of psychotic and nonpsychotic men. Total plasma tryptophan was also determined in blood samples taken simultaneously at the time of lumbar puncture. We report 2 patients, a 42-year-old woman and a 59-year-old man, with chronic HCV hepatitis. Heterologous expression and biophysical characterization of soluble oligosaccharyl transferase subunits.

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