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Bioprim (Trimethoprim)

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This medication is a combination of two antibiotics: sulfamethoxazole and trimethoprim. It is used to treat a wide variety of bacterial infections (such as middle ear, urine, respiratory, and intestinal infections). It is also used to prevent and treat a certain type of pneumonia (pneumocystis-type). This medication treats only certain types of infections. It will not work for viral infections (such as flu). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.

Other names for this medication:
Alfatrim, Avlotrin, Bacsul, Bactrizol, Baktar, Bioprim, Biotrim, Ciplin, Cotribene, Cotrimol, Cotrimox, Cotrix, Daiphen, Diseptyl, Editrim, Eliprim, Erphatrim, Gantrisin, Licoprima, Momentol, Novidrine, Noxaprim, Organosol, Pehatrim, Primadex, Primazol, Ribatrim, Sulfamethoxazol, Sulfametoxazol, Sulfoid, Sulphax, Sulphytrim, Triforam, Trimecor, Trimesulf, Trimexazol, Trimezol, Trisul, Tritenk, Zaxol

Similar Products:
Fasigyn, Lanoxin, Glyburide, Terramycin, Imdur, Symmetrel, Aricept, Chloromycetin

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Also known as: Trimethoprim


Bioprim is effective in a variety of upper and lower respiratory tract infections, renal and urinary tract infections, gastrointestinal tract infections, skin and wound infections, septicaemias and other infections caused by sensitive organisms.

Each Bioprim tablet contains 80 mg trimethoprim and 400 mg sulfamethoxazole.

Each Bioprim DS (double strength) tablet contains 160 mg trimethoprim and 800 mg sulfamethoxazole.


Adults: The usual adult dosage in the treatment of urinary tract infections is 1 Bioprim DS (double strength) tablet or 2 Bioprim tablets every 12 hours for 10 to 14 days. An identical daily dosage is used for 5 days in the treatment of shigellosis.

Children: The recommended dose for children with urinary tract infections or acute otitis media is 40 mg/kg sulfamethoxazole and 8 mg/kg trimethoprim per 24 hours, given in two divided doses every 12 hours for 10 days. An identical daily dosage is used for 5 days in the treatment of shigellosis.


If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe nausea/vomiting/diarrhea, severe dizziness or drowsiness, mental/mood changes.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Side effects

The most common side effects associated with Bioprim are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Generic Bioprim if you are allergic to Generic Bioprim components. Do not take Generic Bioprim if you're pregnant or you plan to have a baby, or you are a nursing mother. Generic Bioprim can harm your baby. Do not take Generic Bioprim if you have anemia. Generic Bioprim can't be given to children younger than 2 months old. Avoid exposure to sunlight, sunlamps, or tanning beds while taking Generic Bioprim. Be careful with Generic Bioprim if you have kidney or liver disease, folic acid deficiency, asthma or severe allergies, AIDS, glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency); if you are malnourished. Be careful with Generic Bioprim if you take seizure medication such as phenytoin (Dilantin); diuretic (water pill); blood thinner such as warfarin (Coumadin); methotrexate (Trexall, Rheumatrex); methotrexate (Trexall, Rheumatrex); or an ACE inhibitor such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace) or trandolapril (Mavik). It can be dangerous to stop Generic Bioprim taking suddenly.

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Protective effects of glutamine on the intestinal mucosal barrier in young rabbits under hemorrhagic shock. Developmental changes in Trichoderma viride enzymes abundant in conidia and the light-induced conidiation signalling pathway. A high number of NF-kappaB p65 positive cells were detected in the inner retina at 12 h after ischemia. Monte carlo simulations of self-assembled surfactant aggregates. Advances in treatment Herpes simplex encephalitis with acyclovir have improved outcome. CCAAT/enhancer-binding proteins alpha and beta interact with the silencer element in the promoter of glutathione S-transferase P gene during hepatocarcinogenesis. It is concluded that relatively low dietary RNA concentrations decrease food intake and growth and cause enlarged kidneys which contains many crystals composed mainly of calcium salts. Carbamylation decreases the cytotoxicity but not the drug-carrier properties of polylysines. The most frequently observed mutation is a deletion of two bases from a (CG)4 run.

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Symptoms of abscisic acid deficiency were generated in the transformants although they have even higher levels of abscisic acid than wild-type plants. Her-2 gene dosage analysis in human breast cancer by PCR with internal standard. Not only do neurons of the ventral tegmental area project to the ventral striatum, but also many of the pars compacta. In the 5-day drug free scans, no regions differed significantly from those in the haloperidol condition, despite numerical changes. Our data therefore indicate that all treatments that induce an enrichment of G1 cells also result in a sensitization of stem cells to cell killing or the induction of mutagenic damage. This study shows a suitable method to describe range of motion and activities of daily living and can serve as a starting point for developing a database on how activities of daily living are performed in a larger population and which joint angles are required to perform these tasks. It seems to be the second example appeared in medical literature. Resting oxygen uptake and oxygen pulse values were not different in the two groups. hominis organisms were isolated from the vagina throughout the course of the experiments and they were cultured also from the cervix and uterine horns.

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We found that the antiangiogenic effects of rosiglitazone were reversed by either bisphenol A diaglycidyl ether, a PPARgamma antagonist, or iberiotoxin, a maxi-K channel blocker. Antioxidant and antiproliferative activity of curcumin semicarbazone. Binding of dimeric Ss-LrpB to all three target sites is accompanied by the formation of globular complexes, in which the protein induces strong DNA deformations. Only 11 Group F patients needed morphine compared with 19 Group P patients, and mean morphine dose was significantly lower in Group F. The objective was to study the long-term effect (2 years) of different training programs in patients with rheumatoid arthritis. Characterisation and chromosomal localisation of the rat alpha- and beta-adducin-encoding genes. A critical assessment of perchloric acid (PCA) brain tissue extracts for precise identification and quantitation of brain metabolites using in vitro proton nuclear magnetic resonance (1H NMR) spectroscopy was studied.

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Bacterial lipopolysaccharide enhances cardiac dysfunction but not retroviral replication in murine AIDS: roles of macrophage infiltration and toll-like receptor 4 expression. A case report of cavitary bronchial carcinoma with intracavitary aspergillosis. ELC protrude markedly toward the lumen of the lung and are surrounded by pneumocytes, which separate ELC from the lumen by thin cytoplasmic processes. pallidum proteins develops at different rates during the time course of infection. The two homodimers (Leu323 and delta 43) were expressed without detectable formation of hybrid receptors. We found a correlation between (i) sites capable of binding both the p50/p65 heterodimer and the high-mobility-group protein HMG I(Y) and (ii) virus inducibility.

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The theory that abnormal intra-uterine fetal position may cause these deformities has gained support over previous concepts, as demonstrated by the baby born by caesarean section. The distribution of NOS-like immunoreactivity (LI) and of these other markers has been semiquantitatively summarized. Genotoxic evaluation of sodium fluoride and sodium perborate in mouse bone marrow cells. We observed a shortage of child psychiatrists and professionals, regardless of the norm used. Systemic effects of S-nitroso-glutathione in the human following intravenous infusion.

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Previous studies have suggested that infection with Helicobacter pylori is associated with an increased risk of gastric adenocarcinoma. The cytostatic effect of some antitumor antibiotics such as carminomycin, olivomycin, bruneomycin, rubomycin C and adriamycin was studied with a rapid method based on measurement of 3H-thymidine and 14C-adenine incorporation into the tumor cells of suspended primary cultures of mouse lymphadenosis NK/Ly. Reliability of the AMS inflatable prostheses in 444 consecutive cases. Further observations on the geographic distribution of multiple sclerosis in the north-central parts of Poland. All children had been removed from parental custody as a result of the maltreatment. Autosomal recessive Melnick-Needles syndrome or ter Haar syndrome?. The level of plasma viscosity associated with the diagnosis of giant cell arteritis, and its use as a replacement for the erythrocyte sedimentation rate (ESR) is examined, by reviewing the records of 59 patients undergoing temporal artery biopsy. Effects of granulocyte colony-stimulating factor on focal cerebral ischemia-reperfusion injury in rats. In a case like this, thrombus is easily formed that may cause acute myocardial infarction and unnecessary coronary angioplasty may be performed. Discounting the debtors will not make medical bankruptcy disappear.

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Hypoestrogenemia and rhabdomyelysis (myoglobinuria) in the female judoist: a new worrying phenomenon?. The use of the technique described in the literature resulted in slight overcorrection of forearm positioning in the nine children. The eIF3 complex is thought to be composed of essential core subunits required for global protein synthesis and non-essential subunits that may modulate mRNA specificity. Visualisation of morphological changes in living intact human microvessels using confocal microscopy. Where there is a clinical need for detection of small changes in analyte concentration, the reporting interval should be kept small relative to the combined variation attributable to assay precision and within-person biological variation. Further analysis of ADAM22 will provide clues to understanding the mechanisms of human diseases such as epileptic seizures and peripheral neuropathy. Person-years of life lost (or saved) were calculated using recent NZ life tables. The physiologic status of the anorectum before and after biofeedback therapy was investigated by anorectal manometry and electromyography of the external sphincter.


Multivariate regression was used for independent analysis of each group and for analysis of the two groups together. Isolation of viroid-RNA-binding proteins from an expression library with nonradioactive-labeled RNA probes. Marked increase in the histamine content of neointima after stent implantation of pig coronary artery and growth-promoting effects of histamine in cultured smooth muscle cells. However over the first 7 hr C18:1, C18:2, C20:5 and C22:6 exhibited stability whereas C16:0 altered. Retinal ischemia was induced in cats, pretreated with HES-DFO, using both the vascular ligation and the increased intraocular pressure models. The expression of IL-1b, IL-2 and IFN-g genes was low or undetectable.

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This distinction with prevalence of one peptide on the other is maintained in the different morphological and pathological conditions of the human thyroid. Clinical features of type 1 autoimmune hepatitis in elderly Italian patients. Stimulation of spinal delta-opioid receptors in mice selectively enhances the attenuation of delta-opioid receptor-mediated antinociception by antisense oligodeoxynucleotide. The C-reactive protein (CRP) in patients with long bone fractures and after arthroplasty. Class V mutations affect the splicing machinery and generate both aberrantly and correctly spliced transcripts, the levels of which vary among different patients and among different organs of the same patient. We discuss the possible etiology of the association between the aneurysm and the arachnoid cyst, and the formation mechanism for the intracystic hematoma that did not result in a subarachnoid hemorrhage. The effects of estimated blood loss and autologous donation on the rate of homologous transfusions were analyzed in 3 groups of 100 consecutive patients treated between 1983 and 1992. Although it usually improves in a few days, reversed clock phenomenon can persist longer.

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The NFHS data collected from 4276 ever-married women in the age group 13-49 years in 1992 (NFHS-I) and 4032 ever-married women in the age group 15-49 years in 1998 (NFHS-II) were analysed. The resins used were Duralay, a methacrylate-based resin, and Protemp II, a bisacrylic resin. The results suggest protection against oxidative degradation of phospholipids and possible inhibition of phospholipases A2 and C, which may result from the elevated level of alpha-tocopherol in the experimental egg yolks. The correlation between temporal changes in the SOD activity, ChL emission, and higher TBARS levels a week later were evident from the data. After the therapy ended the concentration of those values were similar to those in the control group.

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In situ gene expression of growth hormone (GH) receptor and GH binding protein in adult male rat tissues. History and overview of theories and methods of chiropractic: a counterpoint. Expression of mTert in primary murine cells links the growth-promoting effects of telomerase to transforming growth factor-beta signaling. There were two cases of metastatic squamous cell carcinoma and one of melanoma. Diagnosis and treatment of acute aortic dissection during pregnancy are discussed. Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes. In the last decade, the ultrafast dynamics of many atomic and molecular quantum systems in the gas and condensed phase have been controlled successfully.

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Animal and human studies on ferrous fumarate, an oral hematinic. In contrast, viral infection in gld mice, which lack functional FasL, resulted in an inflammation and invasion of ocular tissue without apoptosis. Determination of proliferation activity of prostate cancers by means of nuclear proliferation-associated formalin resistant Ki-S5 antigens. These results indicate that 1,2-DG generated via the phospholipase D pathway activated by tyrosine phosphorylation is a principle source for AA released in response to SCF in mast cells. In vitro studies include the search for anti-insulin antibodies and anti-insulin-receptor antibodies, the study of insulin receptors (insulin binding, tyrosine-kinase activity and gene structure) and of the post-receptor glucose metabolism. The aim of study was to compare the diagnostic efficacy of what happens if you drink alcohol on zithromax the newly introduced DIAGNOdent laser fluorescence with traditional methods for detection of molar caries, namely visual inspection and bitewing radiographs. Effect of meprobamate and emylcamate on human performance in a prolonged serial task. The current treatment of choice for atherosclerotic renal artery stenosis is balloon angioplasty and secondary stenting, whereas angioplasty alone is the treatment for renal artery stenosis secondary to fibromuscular dysplasia. The research is carried on cardiac glands region of the abomasum of the bull by both descriptive and cytochemical ultrastructure. Mouse embryonic fibroblast cells lacking MEKK1 expression are also resistant to etoposide-induced mitochondrial Smac/Diablo release.

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Attenuation of mycotoxin-induced IgA nephropathy by eicosapentaenoic acid in the mouse: dose response and relation to IL-6 expression. Phentolamine activation of glycogenolysis in rat skeletal muscle. Passive smoking causes pulmonary and cardiovascular disease in children and adults. To determine whether the effectiveness of contraceptive services for teenagers is related to the balance of service provision between general practitioners and specialist family planning services. In rare instances, tarsal coalition leads to cavovarus foot deformity, although the pathologic mechanism leading to this deformity is not clear. Hypocholesterolemic effect of amaranth seeds was studied in male wistar strain albino rats as against Bengal gram. After RNAi depletion of dynein-dynactin, we observed subtle but significant mislocalization of KLP10A and Asp, suggesting that dynein-dynactin, Asp, and KLP10A have complex interdependent functions in spindle pole focusing and centrosome attachment.

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As after-hours calls play such an important role in a health care system and are extremely costly it is suggested that education of both doctors and patients is needed to limit calls. The acquisition of Pseudomonas cepacia in patients with cystic fibrosis is associated with increasing deterioration in lung function and more frequent hospital admissions. These results should be useful in order to elaborate synthetic strategies. CNS events are associated with the quinoline and artemisinin derivatives. The process of treatment selection among previously untreated help-seeking problem drinkers.

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Common regression equations for Indians enveloping major studies from various parts of the country have been formulated. In normoinsulinemic patients, glucose plasma levels were increased whereas insulin levels were not modified by the treatments. The results that have been obtained so far by interlaboratory collaboration are very encouraging, and it is hoped that such joint efforts will be expanded in the future. Sequence analysis revealed that the fragments consist of disulfide connected peptides comprising amino acids 1331-1566 and 1331-1697 of the receptor repeats 9-12. For a leukemia with a leukemia count of greater than 10 x 10(9)/L, the immunophenotype obtained is essentially that of the leukemic clone. Exocrine pancreatic proteins what mg does provigil come in in serum during pancreatic allograft rejection.

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Toxic effects and drug interactions of antimycobacterial therapy. Sulfhemoglobinemia is relatively rare, despite the widespread use of drugs that have been reported to cause it. To respond, they must have access to information and know how to manage it effectively to improve their clinical performance and achieve better client outcomes. Counseling readiness and the problem-solving behavior of clients. Compared with that of PH, the effect of the hormone was much more pronounced than is prilosec a brand name or generic name would be expected from the relative mitogenic effect of the hormonal and surgical pre-treatments if the mitotic rate were the cause. Nearly identical results were obtained in brain cytosols from male and female, and young and adult individuals, although further quantitative analyses are needed to investigate possible sex and age relationships. PCR is safe and effective in previously treated patients with CLL. Measurements were made in a basal state 1 hour after ketanserin ingestion and expressed as a ratio of values post- to pre-ketanserin administration. Our aims were to identify objective end points in standard disease activity indices for remission and for improvement in ulcerative colitis.

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GM-CSF-stimulated upregulation of c-fos mRNA expression was not detected in immature cells but developed after 2 to 4 days with DMSO in line with a marked increase in responsiveness to stimulation with phorbol ester, showing that increased expression of c-fos is predominantly a feature of mature phagocytes. Pneumococcal infection resulted in alteration of the composition of the blood but not the bone marrow. Synergistic interaction between c-kit ligand (SCF), GM-CSF and TNF promotes optimal dendritic Langerhans cell proliferation from primitive progenitors in human bone marrow. Heat and rectal volume thresholds were measured again following unilateral and bilateral pudendal nerve block. Janusin coated onto nitrocellulose was a good substrate for attachment of cell bodies and neurite outgrowth after 21 h of culture. Thus, we argue that animal and human studies of individual differences in drug sensitivity be studied from both quantitative and molecular genetic approaches. Imaging-guided percutaneous biopsy of mediastinal lesions: different approaches and anatomic considerations. Functional results of dynamic splinting after transmetacarpal, wrist, and distal forearm replantation.

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Dietary determinants of long-term incidence of chronic nonspecific lung diseases. The lattice-Boltzmann method has shown promise in simulating multiphase flows. Meanwhile, cultures of isolate (043) from a patient treated with AZT for 2 months showed CPE in the presence of 0.1 microM AZT. The mechanism of titanocene mediated 3-exo cyclizations was investigated by a combined theoretical and experimental study. To investigate the relationship between the histologic phase and the quantitative expression of epidermal growth factor receptor (EGFR) mRNA in the endometrium of normal and leiomyomatous uteri. with melanoma cells pretreated with Polyerga in vitro or previously not treated. Polyamine neurotoxicity is antagonized by dizocilpine in cultured chick cortical neurons. Differential sensitivity to maternal cyclophosphamide treatment.

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