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Biger (Atorvastatin)
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Biger

Biger is a lipid-lowering drug included in the statin class of medications. By inhibiting the endogenous production of cholesterol in the liver, statins lower abnormal cholesterol and lipid levels, and ultimately reduce the risk of cardiovascular disease. More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase, which catalyzes the conversion of HMG-CoA to mevalonic acid.

Other names for this medication:
Anvistat, Atacor, Atorsan, Atorva, Atorvastatina, Atova, Atroact, Aztor, Biger, Danelip, Delipost, Holisten, Hypolip, Larus, Lipicon, Lipigan, Lipivastin, Lipovast, Liprimar, Liptor, Locol, Lowlipen, Tarimyl, Torvazin, Vastina, Voredanin, Xelitor

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Also known as: Atorvastatin

Description

Generic Biger is made by highly educated specialists to combat high cholesterol diseases (heart attack, stroke). Target of Generic Biger is to control and decrease level of cholesterol. Generic Biger acts as an anti-high cholesterol remedy. Generic Biger operates by reducing decrease level of cholesterol. Biger is also known as Atorvastatin, Atorbest, Agitor, Attor, Atorlip, Lipvas, Sortis, Torvast, Torvacard, Totalip, Tulip. Generic Biger is HMG-CoA reductase inhibitor (statin). Generic name of Generic Biger is Atorvastatin. Brand name of Generic Biger is Biger.

Dosage

Take Lipitor exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Lipitor is usually taken once a day, with or without food. Take the medicine at the same time each day.

Do not break an Lipitor tablet before taking it, unless your doctor has told you to.

You may need to stop using this medicine for a short time if you have:

uncontrolled seizures; an electrolyte imbalance (such as high or low potassium levels in your blood); severely low blood pressure; a severe infection or illness; or surgery or a medical emergency.

It may take up to 2 weeks before your cholesterol levels improve, and you may need frequent blood test. Even if you have no symptoms, tests can help your doctor determine if Lipitor is effective.

Lipitor is only part of a complete treatment program that may also include diet, exercise, and weight control. Follow your doctor's instructions very closely.

Store at room temperature away from moisture, heat, and light.

Detailed Lipitor dosage information

Overdose

If you overdose Generic Biger and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 20 to 25 degrees C (68 to 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Biger are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Lipitor if you are allergic to atorvastatin, or if you have:

liver disease; or if you are pregnant or breastfeeding.

Atorvastatin can harm an unborn baby or cause birth defects. Do not use if you are pregnant. Stop taking Lipitor and tell your doctor right away if you become pregnant. Use effective birth control to prevent pregnancy while you are taking this medicine.

Atorvastatin may pass into breast milk and could harm a nursing baby. Do not breastfeed while you are taking Lipitor.

To make sure this medicine is safe for you, tell your doctor if you have ever had:

liver problems; muscle pain or weakness; kidney disease; diabetes; a thyroid disorder; or if you drink more than 2 alcoholic beverages daily.

Lipitor can cause the breakdown of muscle tissue, which can lead to kidney failure. This happens more often in women, in older adults, or people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid).

Atorvastatin is not approved for use by anyone younger than 10 years old.

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The conditions used for alkaline treatment were previously reported for cleavage of the covalent linkage between bikunin and H3 inside pre-alpha-trypsin inhibitor (Enghild et al. The first utilized comparative hybridization to rodent-human hybrid cell DNA samples containing all or known portions of the human X, while the second was based on hybridization dosage to DNA samples from human cell lines differing in the number of X chromosomes or X chromosome segments. Effective extraction and purification of beta-xylosidase from Trichoderma koningii fermentation culture by aqueous two-phase partitioning. Lack of cytoplasmic detail in ethanol-cryofractographs has been due more to the nature of the fracturing of the tissue and to the obscuring effects of the metal coating than to structural deformation at the fracture edge or to limitations in resolving power of the scanning electron microscope used. Using the yeast two-hybrid method and a mouse brain cDNA library, we have identified an interaction between a partial cDNA encoding the globular domain IV of laminin chain beta1 and the amino acids 240-503 of mouse AChE.

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In light of the difficulty in reaching an early etiologic diagnosis in respiratory infections, it is essential to invest in the development of a compact diagnostic kit for the early stages of the disease, which could change reality in this important area of medicine. Both of ECR-1 and ECR-6 probes could be applied for the taxonomy, epidemiological and microecological studies, and clinical diagnosis for pathogenic Escherichia coli strains. Cross-sectional echocardiography showed a sigmoid-shaped interventricular septum markedly protruding into the left ventricle, concentric left ventricular hypertrophy, systolic anterior motion of the mitral valve, and a resultant left ventricular outflow tract obstruction with a pressure gradient of 121.8 mmHg. Determination of the number of ion-binding sites and their position in the gramicidin channel. These scores provide researchers with externally validated and clinically relevant cut-off scores in designing trials in the management of older depressed community residents. This information can be useful to anticipate the growth of wildfires through the landscape with an associated probability of occurrence. Choose beverages and foods to moderate your intake of sugars: measurement requires quantification. Alternatively, we also show that when two species are distributed according to the IFD, the corresponding population equilibrium can be unstable.

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Assessing the impact of general practitioner team service on perceived quality of care among patients with non-communicable diseases in China: a natural experimental study. Isolation of alpha 1-protease inhibitor from human normal and malignant ovarian tissue. This study sought to determine whether apoptosis of T cells is actively inhibited in patients with uveitis and by what pathways this may occur. The effect of O3 exposure (3 ppm, 1 h) on the in vivo and in vitro airway responsiveness, as well as the changes in cell contents in bronchoalveolar lavage (BAL) fluid, were evaluated 16-18 h after O3 exposure in sensitized and nonsensitized male guinea pigs. plus (Leitz Texture Analyzer System) and a programme devised by the authors in the TASIC language. Activating effect of nasal air flow on epileptic electrographic abnormalities in the human EEG. Relative concentrations of polyaromatic primary amines and azaarenes in mutagenically active nitrogen fractions from a coal liquid.

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RNAase 1 inhibits DNA synthesis and increases degradation of RNA in granulation-tissue fibroblasts but RNAase 2 at the same concentration does not have these effects. Pyrimidinone compounds 2-amino-5-bromo-6-methyl-4-pyrimidinone (ABMP), 2-amino-5-brome-6-phenyl-4-pyrimidinone (ABPP), and 2-amino-5-iodo-6-phenyl-4-pyrimidinone (AIPP) were studied for their activities against artificial lung metastases of the weakly immunogenic spontaneous fibrosarcoma NFSa, the moderately immunogenic spontaneous mammary carcinoma MCa-K, and the strongly immunogenic 3-methylcholanthrene-induced fibrosarcoma FSa syngeneic to inbred C3Hf/Kam mice. Recent papers showing how PGCs migrate when cultured in vitro on cellular monolayers are reviewed. Effects of sodium salicylate, aminopyrine and chlorpromazine on behavioral temperature regulation. These data suggested that after selenite injection, calpain II was activated by elevated free calcium in the nucleus, and that calpain II-induced proteolysis of nuclear proteins was an important mechanism in selenite cataract. Clonal cell lines were derived by selection for a marker gene coding for G418 resistance in the absence or presence of the hematopoietic growth factor IL-3.

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Ribonucleotide pairs including uridylic acid are less active, but 3 ribonucleotide combinations are highly effective, even in the presence of uridylic acid. Regulation of expression of the early growth response gene-1 (EGR-1) in malignant and benign cells of the prostate. These data indicate that DNA ploidy is a strong and independent prognostic factor in patients with non-small cell lung carcinoma. Visible mutations induced by P-M hybrid dysgenesis in Drosophila melanogaster result predominantly from P element insertions. To evaluate the diagnostic performance of superb microvascular imaging (SMI) in breast lesions, comparing with contrast-enhanced ultrasonographic microvascular imaging (MVI). According to a number of their properties, mdg elements are quite similar to endogenous pro-retroviruses. They achieved results comparable to those obtained with similar patients and methods by psychologists and psychiatrists. A better understanding of the expression frequency and prognostic value of mesothelin in TNBC will be essential to identifying a novel therapeutic target. Newer therapies hold great promise for the future treatment of allergic respiratory diseases, but clinical trials are necessary to accurately evaluate risk-benefit ratios of IgE immunomodulators.

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Beta-adrenergic receptor function was assessed in cultured skin fibroblasts obtained from bipolar patients and normal volunteers by measurement of the cyclic adenosine monophosphate (cAMP) response to isoproterenol. Preliminary in vivo tumor assay also indicated that these compounds were active against Walker 256 carcinosarcoma in rats and were inactive against both L1210 lymphoid leukemia and Ehrlich ascites carcinoma in mice. Five novel metabolites of 5-oxo-ETE were identified including 5,18-diHETE, 5,19-diHETE, 5-oxo-19-HETrE, 5-oxo-18-HETrE, and 5,19-diHETrE. coli and coliforms, respectively, is recommended for testing samples of surface water according to the EC guidelines for bathing waters (no. Serotyping of Escherichia coli is useful, but complex, with 173 O antigens, 80 K antigens, and 56 H antigens, which can all be subdivided into partial antigens.

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The epitope of 9O12 was mapped by phage display, along with molecular modeling of human GPVI, which allowed the identification of residues within GPVI potentially involved in ligand recognition. Confirmation for this second epitope was provided by peptide walking analysis. No stones were found in the sham and proximal gastric vagotomy groups. Continuous exposure of the chick embryo to l-alpha-noracetylmethadol does not alter brain protein or nucleic acid content. A primary cell culture system was used to obtain differentiated rainbow trout (Oncorhynchus mykiss) macrophages that were stimulated with Escherichia coli lipopolysaccharide (LPS-10 microg/ml) for 12 h in vitro. Any nucleic acid components which were formed on the primitive earth would tend to hydrolyze by a number of pathways. It is particularly useful for the detection of gallstones and the diagnosis of acute cholecystitis.

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To investigate the effect of insulin-like growth factor 1 (IGF1) on the release of collagen, and the production and expression of matrix metalloproteinases (MMPs) induced by the proinflammatory cytokine interleukin 1alpha (IL1alpha) in combination with oncostatin M (OSM) from bovine nasal cartilage and primary human articular chondrocytes. Sixteen health professionals and two women from the community were interviewed, and the labor and delivery records from 1985 to 1990 were reviewed for parity, child spacing, and health status of the women and newborns. Hormone receptor-coupling factor-adenylate cyclase interaction: theoretical considerations. According to their staining pattern astrocytes were classified into 4 cell types: Type I cells were seen during the non-proliferating period, Type II cells during the low-proliferating period, Type III cells during the moderate-proliferating period and Type IV cells during the high-proliferating period. U-73122, an aminosteroid phospholipase C antagonist, noncompetitively inhibits thyrotropin-releasing hormone effects in GH3 rat pituitary cells. Behavior and significance of urinary excretion of alpha-glucosidase, gamma-glutamyltransferase, lysozyme and beta 2 microglobulin. Some interrelations between ascorbic acid and adreno-cortical function. Measurement of absorbed fractions for photon sources distributed uniformly in various organs of a heterogeneous phantom. The follicular phase was associated with a significant P180 latency asymmetry under baseline or placebo conditions. The mean Se intake of the population, calculated on the basis of food consumption statistics and from the data of urinary Se excretion, as well as the average serum Se concentration of both urban and rural people increased also during the same period.

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Similar motor effects of 5-HT and TRH in rats following chronic spinal transection and 5.7-dihydroxytryptamine injection. Overall survival is increased among stage III pancreatic adenocarcinoma patients receiving neoadjuvant chemotherapy compared to surgery first and adjuvant chemotherapy: An intention to treat analysis of the National Cancer Database. Chronic cold stress reduces the spontaneous activity of ventral tegmental dopamine neurons. Predictive factors for regression of gastric MALT lymphoma after anti-Helicobacter pylori treatment. Minimal diffuse staining over most cellular components was observed with the LH antiserum.

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The authors discuss the practical and heuristic implications of these observations and suggest further consideration of therapy directed toward enhancement of cholinergic activity in the central nervous system. We retrospectively reviewed the records of 56 cases in 47 patients who had undergone THA with short metaphyseal loading femoral stem from April 2010 to December 2011. Heterotopic autotransplantation of cryobanked human ovarian tissue as a strategy to restore ovarian function. Consistent with its role in innate immunity, MMP-7 is induced by microbial products and also, unexpectedly, by hypoxia. Determination of 3-phenyl-2-thiohydantoin-amino acids by means of in situ quantitation of thin-layer chromatograms.

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Induction of calcitonin receptors by 1 alpha, 25-dihydroxyvitamin D3 in osteoclast-like multinucleated cells formed from mouse bone marrow cells. The effect of insulin on glucose uptake in soleus muscle during hemorrhagic shock. Changes in intracellular calpastatin localization are mediated by reversible phosphorylation. Effects of mepartricin on the growth of hypertrophic prostatic tissue in primary culture. In the future, innovative biotechnologies may offer new routes to reduced emissions pathways especially when applied to the vast unconventional heavy oil resources formed, paradoxically, from microbial activities in the geological past. However, there are no clear subfamilies of the channels, unlike the situation with potassium and calcium channels.

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Evidence for glucocorticoid receptor transport on microtubules by dynein. The impact of microsurgery and the ability to teach it to successive generations of neurosurgeons during the last 25 years are surely the material from which the future history of neurosurgery will be written. The subjects consisted of 1 case of DPB and 3 cases of bronchiectasis. Juvenile hormone regulation of the E75 nuclear receptor is conserved in Diptera and Lepidoptera. Higher negative symptom scores (total SANS) and greater functional impairment (lower GAF) were reported in subjects who reported a later age at menarche. Kaplan-Meier curves and Cox proportional hazards regression model were used to assess the association of TLR9 and NFKBIA with clinical outcomes of patients. Studies using BMI, rather than weight alone, can provide information about whether body composition is related to contraceptive effectiveness. We related their blood pressure to patterns of fetal growth, as measured by body proportions at birth. Blood and urine radioactivity measurements were performed at selected intervals. Diuretic effects of triamterene combined with hydrochlorothiazide.

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Efforts to reduce costs will require attention to supply-sensitive services (the frequency of hospital stays, physician visits, specialist consultations, diagnostic tests, and minor procedures) and should include a focus on the longitudinal efficiency of hospitals and medical staffs. In all other respects however, the double mutant exhibits the am phenotype. Tacrolimus (FK506), which is isolated from Streptomyces tsukubaensis, is a new potent immunosuppressant. Measurement of urinary methoxyphenols and their use for biological monitoring of wood smoke exposure. Dysfunction of natural killer cells in multiple sclerosis: a possible pathogenetic factor.

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We demonstrate that TGGE is an effective method for analysis of TCR gene rearrangement in the evaluation of nodal and extranodal lymphoid lesions. The project carried out a pre- and post-implementation audit procedure using the Joanna Briggs Institute Practical Application of Clinical Evidence System and Getting Research into Practice programs. TNF-alpha and IL-1beta-mediated regulation of MMP-9 and TIMP-1 in renal proximal tubular cells. Areas 3b and 1 contained parallel mirror-image representations of cutaneous receptors and a parallel representation in area 2 was probable. maculipennis was first recorded for Tadjikistan and should be included into the list of malaria mosquitoes of the republic. The proteins which proved to be upregulated or downregulated in 2-DE gel were digested with trypsin and identified with matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF) and electrospray ionization quadrupole (ESI-Q) TOF-mass spectrometry. Neurochemical changes in the rat brain after intraventricular administration of tryptamine-4,5-dione. Characteristics of the antigenic composition of influenza A (H3N2) virus hemagglutinins isolated 1979-1080. A single-dose metyrapone test, performed to confirm the diagnosis of adrenal insufficiency, gave unexpectedly normal results. Clusters of responses with similar time courses which often occurred together in series of 100 responses were detected using a microcomputer program.

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Use of paracetamol-phenylbutazone combination in rheumatic diseases of professional motorists. Our chemomechanical modeling reveals the mechanical confinement effects in lithiated a-Si nanotubes with and without SiOx coatings. To assess the activity of chemotherapy with cisplatin, vindesine and mitomycin-C (PVM) in advanced non-small-cell lung cancer (NSCLC) and to test the feasibility of preemptive therapy with PVM. The increased mutation rate of Mutator stocks of maize has been shown to be the result of transposition of Mu elements. GaAs nanowires with oxidation-proof arsenic capping for the growth of an epitaxial shell. Oxygen delivery, oxygen consumption and hemoglobin-oxygen affinity in acute myocardial infarction. Temperature-sensitive albino gene TCD5, encoding a monooxygenase, affects chloroplast development at low temperatures. In the presence of phentolamine, stimulation of zithromax z pak azithromycin dosage the cat splanchnic nerve decreased the resistance of the superior mesenteric arterial bed. By limited proteolysis, plasma kallikrein cleaves high Mr kininogen to liberate kinin and gives a molecule containing two disulfide-linked polypeptide chains. The results showed that microscopical acanthosis is related to an increase of the germinative population, while the increased epidermal turnover is associated with increased numbers of cycling cells.

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