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Biclar (Clarithromycin)
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Biclar

Biclar belongs to a group of medicine called macrolide antibiotics derived from Saccharopolyspora erythraea (originally called Streptomyces erythreus), used to treat a wide range of bacterial infections including chest infections such as bronchitis and pneumonia, skin problems such as cellulitis (potentially serious bacterial skin infection.

Other names for this medication:
Abbotic, Aeroxina, Bicrolid, Binoclar, Biotclarcin, Bremon, Cidoclar, Clabact, Clacee, Clacina, Clacine, Clarimac, Clarimax, Claripen, Clariston, Claritab, Clarithromycin, Clariwin, Claromycin, Claron, Clarosip, Clathrocyn, Clonocid, Eliben, Emimycin, Eracid, Euromicina, Geromycin, Glartin, Heliclar, Helozym, Infex, Italclar, Kailasa, Kalixocin, Klabet, Klarifor, Klarith, Klaritpharma, Kofron, Larizin, Laromin, Macromicina, Onexid, Quedox, Rocin, Rodizim, Rolicytin, Zeclaren

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Also known as: Clarithromycin

Description

Clarithromycin is used to treat bacterial infections in many different parts of the body. It is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori. This medicine is also used to prevent and treat Mycobacterium avium complex (MAC) infection.

Clarithromycin belongs to the class of medicines, known as macrolide antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.

Dosage

The recommended daily dosage is 15 mg/kg/day divided every 12 hours for 10 days (up to the adult dose). Refer to dosage regimens for mycobacterial infections in pediatric patients for additional dosage information.

For the treatment of disseminated infection due to Mycobacterium avium complex (MAC), Biclar Filmtab and Biclar Granules are recommended as the primary agents. Biclar Filmtab and Biclar Granules should be used in combination with other antimycobacterial drugs (e.g. ethambutol) that have shown in vitro activity against MAC or clinical benefit in MAC treatment.

For treatment and prophylaxis of mycobacterial infections in adults, the recommended dose of Biclar is 500 mg every 12 hours.

For treatment and prophylaxis of mycobacterial infections in pediatric patients, the recommended dose is 7.5 mg/kg every 12 hours up to 500 mg every 12 hours.

Biclar therapy should continue if clinical response is observed. Biclar can be discontinued when the patient is considered at low risk of disseminated infection.

Overdose

Overdose symptoms may include severe stomach pain, nausea, vomiting, or diarrhea.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not refrigerate or freeze the oral liquid. Throw away any unused mixed medicine after 14 days.

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The most common side effects associated with Biclar are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Discontinue immediately if hepatitis or severe hypersensitivity reactions occurs. Severe renal impairment. Proarrhythmic conditions (eg, hypokalemia, hypomagnesemia, bradycardia); avoid. Myasthenia gravis. History of porphyria; avoid concomitant ranitidine bismuth citrate. Elderly. Pregnancy (Cat.C): usually not recommended. Nursing mothers.

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The percutaneous rotary lithotrite: a new approach to the treatment of symptomatic cholecystolithiasis. Cultured RA and type B synoviocytes can perform some of the functions of professional antigen-presenting cells. These equivalent responses may be related to the relatively small output of proximally induced accommodation believed to be present under closed-loop conditions. The Food and Drug Administration (FDA) is a section of the Department of Health and Human Services of the United States Government, and its primary responsibility is to control the distribution of food, drugs, and medical devices within the country while ensuring public safety. A novel mouse Smad4 mutation reduces protein stability and wild-type protein levels.

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