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Betrol (Glibenclamide)

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Betrol is an oral diabetes medicine that helps control blood sugar levels. Betrol is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.

Other names for this medication:
Afdiex, Benformin, Betanase, Betrol, Bionil, Combidos, Daocon, Daonil, Diabnil, Diolin, Euglucon, Giclamide, Glibact, Glibenclamide, Glime, Glitrac, Glucomin, Gluconil, Glucored, Glucosil, Glunil, Glutowin, Glybonil, Glybovin, Glymep, Melitus, Monomet, Pionorm, Sugatrol, Sugnl, Symet, Triglycomet

Similar Products:
Effexor, Imuran, Glucotrol, Avelox, Persantine, Compazine, Lamisil

Also known as: Glibenclamide


This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For type 2 diabetes:
    • For oral dosage form (tablets):
      • Adults—At first, 2.5 to 5 milligrams (mg) once a day taken with breakfast or the first main meal. Your doctor may adjust your dose if needed. However, the dose is usually not more than 20 mg per day.
      • Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can cause severe hypoglycemia or lactic acidosis.


Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach.

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website ( for more information if you do not have access to a take-back program.

Side effects

The most common side effects associated with Betrol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of glyburide in the pediatric population. Safety and efficacy have not been established.

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Genetic influences on differentiation, mitosis, and dystrophies of the corneal endothelium. Water-loss, according to Peter-Passmore formula, and urinary sodium and potassium excretion were measured at 4-hours intervals. The thoracolumbar spine is inherently unstable, and early operative intervention improves mobilization and rehabilitation. A new application area in the practical usage of magnetic resonance imaging (MRI) has been identified as a methodology of stereotactic operation. A wide range of CTLpF against all three groups of targets was found in both the primigravid and multiparous women, reflecting the wide range of frequencies found in random populations. In one patient, the SPECT abnormality was more extensive than the associated abnormalities on CT and MRI. Emotional ailments, help seeking behaviors and care expectancies in a marginal-urban community. In the majority of patients orthodontic treatment will be required before this space can be restored satisfactorily.

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Comparison of organic and cultural-familial retardates on two visual-motor tasks. She also complained about a persistent headache and depressed mood that began shortly after the accident. In 19 patients with different supraventricular tachycardias the antiarrhythmic drug AWD-G256 was studied to investigate the effects on hemodynamic parameters. In 1991 2 studies were published in which patients with mild and moderate heart failure were included. Our strategy was to use this property of LNA to inhibit undesired PCR amplification (e.g.,from contaminating genomic DNA) in a cDNA-based assay. Immunoblot studies were carried out to determine the nature of reactive determinants. Normal development of the hyaloid and retinal vessels in the rat. beta 1-4 N-acetylglucosaminyltransferase (GnT-III) catalyzes the formation of bisecting N-acetylglucosamine (GlcNAc) in the biosynthesis of N-linked oligosaccharides. Changes in regional cerebral blood flow during auditory cognitive tasks--a PET activation study with odd-ball paradigm. Superoxide formation and lipid peroxidation by the mitochondrial electron-transfer chain.

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Efficacy of Cymelarsan in the treatment of natural chronic Trypanosoma evansi infection in camels in the Sudan. We found that, in men, 10 min infusion of 120 micrograms/kg/min adenosine increased the arterial flow and to some extent venous resistance, resulting in full erection or tumescence. Postvitrectomy bacterial endophthalmitis caused by organisms other than coagulase-negative staphylococci has a poor visual prognosis. Patients can act as experts during the process of questionnaire construction. Among various additives, bile salts such as Na-GC and Na-DC were the most effective for increasing the cytotoxicity of MMC against L1210 cells. The reduction in metabolism preceded any change in thyroid hormone concentrations, and infusions of epinephrine did not restore reduced metabolism to normal levels. New strategies for therapy of IPF followed, including anti-fibrotic agents and interferon gamma treatment. Evaluation of body composition by dual energy x-ray absorptiometry and two different software packages. Needs of occupational exposure sampling strategies for compliance and epidemiology. subtilis NBRC 16183) inoculated onto a stainless steel Petri dish and treated at nine levels of water activity (a(w)) for 2 days were inactivated by infrared radiation heating (IRH) using three kinds of infrared heaters with different radiation spectra.

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We have shown in this small exploratory study that the anti-angiogenic effect of irradiation has a predictive value of the success of radiotherapy in locally advanced OPCC and can be used to select a radioresistant patient population which might require a more aggressive protocol. Effect of splinting on reflex inhibition and sensorimotor stimulation in treatment of spasticity. Immunohistochemistry and immunocytochemistry xanax bars blue mg demonstrated that BmColIV was present in the basement membrane and in the secretory granules of granular cells, respectively. However, few research efforts have addressed the issue of multistep vector pattern recognition. A breast ductus carcinoma, a cervical neuroblastoma, and an apoduma of unknown origin, were the primary neoplasms. Four hundred and thirty consecutive children with serologically confirmed congenital toxoplasmosis were included in this study. Eight-week-old mice born to infected and noninfected mothers were infected with 200 S. In this prospective, randomized, double-blind clinical trial, we gave gabapentin 1200 mg or placebo two hours prior to induction of anesthesia to patients undergoing elective thyroidectomy.

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Using various, previous published in vitro immunization protocols with and without antigen, we were able to show that IgM antibody production was not induced by the antigen. We propose a model for an invertase-mediated unloading process during early seed development and the regulation of trileptal mg amounts cotyledonary sucrose metabolism. Although these results support the idea that c-fos plays a role in proliferation of uterine epithelial cells, they also invite reassessment of the role played by c-fos in both epithelial and nonepithelial uterine cell types. One member of the family, PADI4, plays an important role in immune cell differentiation and cell death. The current compounds are structurally related to previous substrates that we have evaluated, but offer additional three dimensional aspects compared to the series of compounds previously utilized to define the original models. First-order isostructural Mott transition in highly compressed MnO.

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Can a baseline prostate specific antigen level identify men who will have lower urinary tract symptoms later in life?. We use this measurement to compare surfaces that exhibit a clear difference in their solubility properties, namely, a) the solvent accessible surfaces for a set of homo-dimers and the surfaces buried in their interfaces and b) for a set of monomers the surfaces of fragments of secondary structure which are solvent accessible/inaccessible. Local anaesthetics and antiarrhythmic agents produced changes in responses of rabbit platelets to ADP and thrombin that varied with the agent and its concentration. Finally, a brief summary comparing the different techniques is given. However, harmful effects have been associated also with the use of dipivefrin and here we report of a case of corneal vascularization during long-term use of dipivefrin. The importance of using a morphologically derived differential diagnosis to guide the selection and interpretation of immunohistochemical studies is emphasized, and the varying utility (specificity) of the individual immunohistochemical markers within each setting is addressed. The method is demonstrated by in vivo imaging of NAA in human brain at 1.5 T with 10 slices of 16 x 16 pixels spectroscopic images acquired in a total scan time of 17 min.

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Gas chromatographic separation of isomeric 16- and 17-oxosteroids. The observation that RIIbeta(-/-) mice are more sensitive to the effects of repeated ethanol administration suggests that normal protein kinase A signaling limits, or is protective against, the stimulant effects of ethanol and the plastic alterations that underlie behavioral sensitization. Expression of proteins with or without signal peptides was examined and compared in E. Expression of some hepatocyte-like functional properties of WRL-68 cells in culture. Physical activity and the risk of ovarian cancer: a case-control study in Canada. Radiation pneumonitis in rats and its modification by the angiotensin-converting enzyme inhibitor captopril evaluated by high-resolution computed tomography. Sensitivity and specificity data from four reports on two bipolar screening instruments (the Mood Disorders Questionnaire and the Bipolar Spectrum Diagnostic Scale) were used to calculate positive and negative predictive values at varying prevalence levels. Acute administration of sustained-release isosorbide-5-nitrate significantly reduces the size of exercise-induced perfusion defects as assessed using quantitative Tc-99m-MIBI-SPECT.

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The origin of actinomycetes and, except for bifidobacteria, the order by which the main sublines evolved, cannot yet be determined with certainty. The ameloblasts at the stage of enamel maturation were divided into two groups with respect to their distal cell borders: ruffle-ended (RA) and smooth-ended ameloblasts (SA). To determine the costs of health services and the financial consequences of changes in the epidemiological profile of chronic imovane 7 5 mg diseases in Latin America. Cerebroventricular propranolol elevates cerebrospinal fluid norepinephrine and lowers blood pressure. Alpha-interferon seems to be an effective agent for the treatment of MC. Central administration of angiotensin I or II induced significantly smaller increases in blood pressure and drinking in captopril-treated rats and the rats removed from therapy compared with control rats. Selected patients underwent a biopsy, with appropriate additional therapy.

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The purpose of the study here reported was to measure the IFP in human melanoma xenografts and to search for possible correlations between tumor IFP and fractional tumor water content, tumor wet weight, or tumor volume-doubling time. The C-ELISA was evaluated for specificity and sensitivity in naturally and experimentally BLS infected and uninfected broiler and layer breeds of domestic fowl. The equations of motion for a standing human reveal three mechanisms for balance. The interleukin-10-deficient (IL-10-/-) mice maintained in specific-pathogen-free (SPF) conditions develop typhlocolitis when experimentally infected with Helicobacter species. coli harboring appY plasmids produced 2.8 mg lycopene/g dry cell weight (DCW), the same amount obtained with dxs despite the fact that appY is not directly involved in the lycopene synthesis pathway. With both methods, we found a rapid eulexin dosing decrease of pain down to one-half of the preoperative value. Radioisotope renography in the assessment of renal function in the newborn. Furthermore, platelet aggregation was significantly slowed down, whereas ATP release significantly increased in the HHES group. First experience with intra-renal fenoldopam in a patient with heart failure.

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Acute rheumatic fever at first glance, Brucella with a glance in depth. Our studies assign an outgroup position to Neotropical cichlids in relation to African cichlids, provide evidence for a sister-group relationship of tilapiines to the haplochromines, group Cyphotilapia frontosa with the lamprologines of Lake Tanganyika, place Astatoreochromis alluaudi to an outgroup position with respect to other haplochromines of Lakes Victoria and Malawi, and provide additional support for the monophyly of the remaining Lake Victoria haplochromines and the Lake Malawi haplochromines. Rate of over-diagnosis of breast cancer (in situ and invasive), calculated as incidence in the invited and control groups, during period of randomised design (period 1), during period after randomised design ended (period 2), and at end of follow-up. The clinical manifestations of AIDS-related microsporidiosis range from mild or asymptomatic infections to debilitating illness involving the gastrointestinal, respiratory, or urogenital tracts or the eyes. Heat-inducible proteins that react with antibodies to chaperonin60 are localized in the nucleus of a fish cell line. On the other hand, in the SRPC group cellular density was greater.

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