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A stochastic simulation describing the reproductive cycle of first-parity cows was done, in which true breeding values for conception rate were created. We have shown that PCNA and the cell-cycle regulator p21WAF1 interact in vivo, and that this interaction requires the central loop of PCNA and an eight amino-acid motif from the carboxyl terminus of p21WAF1.(ABSTRACT TRUNCATED AT 250 WORDS). Histological outcome in patients with chronic hepatitis C given a 60-week interferon alfa-2b treatment course. The GP64-pseudotyped vector was stable in the presence of human or mouse complement. The synthesis of angustmycin A (decoyinine) and related unsaturated nucleosides. In macrophage-differentiated LSTRA cells, the inflammatory cytokine interferon-gamma was found to be a potent inducer of nitric oxide production. PTH is in clinical use for the treatment of osteoporosis and is under intensive investigation for its potential in applications of tissue engineering, fracture healing, and implant integration. Whereas no differences were found among the rat pups in thresholds for movements accompanying stimulation, epileptic afterdischarges demonstrated a lower threshold in 18-day-old in comparison with 25-day-old animals. We demonstrate that PDGF-stimulated smooth muscle cells activate the STAT (signal transducers and activators of transcription) family of proteins in addition to other signaling pathways (e.g., RAS-RAF-MAP Kinase).
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However, the combination of both techniques may provide additional accuracy. The serum level of HRP was reduced significantly in capsaicin-administered rats compared to control rats along the time course with quantitative analysis of the enzyme immunoassay. A complementarity principle between MCD and CD spectra of transition metal complexes is discussed. The mean time from resection to study was 14 months (range, 4 to 49 months). The islet-acinar axis of the pancreas: is there a role for glucagon or a glucagon-like peptide?. This cell organelle may therefore be considered as a target for drugs directed against tumor cells of advanced cancer. An unusual case of acute abdomen as a distinct manifestation of severe preeclampsia is described. Our findings suggest that ethylene can regulate the magnitude and blend of induced volatile emissions during pathogen infection. Insufficient bonding of juxtaposed bone to an orthopedic/dental implant could be caused by material surface properties that do not support new bone growth. To study the association of increased serum group II phospholipase A2 concentrations to C-reactive protein concentrations in the sera of critically ill surgical patients.
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Head-down tilt results in elevation of plasma ANP in healthy pregnant women, while the same manoeuvre induces down-regulation of the reninangiotensin-aldosterone system in non-pregnant women and patients suffering from pre-eclampsia. Because these jets are of unclear clinical significance, we sought to determine if urologists and radiologists nationally agree on the clinical utility of ureteral jets. Practicability of cataract surgery at university hospitals: searching for an economic model. The Vmax of MCA and ACA in the affected side were lower than the healthy and normal side. Aarskog syndrome: report of a family with review and discussion of nosology. A variety of international organizations, professional groups and individuals are promoting evidence-informed obstetric care in China. This tension thinning appears to follow the power law with respect to the elongation rate, i.e., eta approximately epsilon(b), where the exponent b is shown to be approximately -0.4 for eta1 and eta2. gingivalis to study the metabolism of radiolabelled testosterone by these periodontal pathogens. Articles that reported on pregnancy in patients with the Marfan syndrome or that discussed potentially relevant aspects of the syndrome.
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It is now clear that the great majority of individuals who develop Type 1A diabetes show both immunologic and metabolic abnormalities before the development of overt diabetes. Clinico-functional data concerning chronic asthmatic bronchitis patients treated wih guacetisal. A point mutation in the cytoplasmic domain of Fas (a single base change from T to A at base 786), replacing isoleucine with asparagine, abolishes the signal transducing property of Fas. SDF-1alpha/CXCL12 did not induce tyrosine phosphorylation of Cbl or Cbl-b in Lck-deficient T cell line J.CaM1.6 or CD45-deficient T cell line J45.01. Wilcoxon paired tests revealed significant differences between DSA, DUS and measurements on histological specimens. Our results show that algal growth exhibited pronounced differences in axenic treatments and when bacteria were present.
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This pattern is consistent with modern theories of synthesis, transfer, and export of extracellular macromolecules. Receiver-operating characteristic (ROC) curves provide a cutoff-independent method for the evaluation of continuous or ordinal tests used in clinical pathology laboratories. We suggest that the decline of micronuclei was due to repopulation of lymphocytes and acquired drug resistance. These are groups where socio-economic differences in mortality based on occupation can be difficult to interpret. Information is given about documentation, one- and twodimensional statistics, estimation of diagnostic validity and multivariate analyses. PSM-R: Revised Optimism-Pessimism Scale for the MMPI-2 and MMPI. Recurrent attacks of subarachnoid haemorrhage in presence of a cerebral angioma and an intraventricular oligodendroglioma. Proliferating cell nuclear antigen (PCNA) is a nuclear protein synthesized in G1/S-phase of the cell cycle and therefore is related to cell proliferative activity. The present study was undertaken to clarify whether such assays can detect mutations induced after treatment of male germ cells in mouse with isopropyl methanesulfonate (iPMS), ethylnitrosourea (ENU) or X-ray irradiation. Use of a standardized-patient-based clinical performance examination as an outcome measure to evaluate medical school curricula.
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They can be a manifestation of epilepsy, brain stem tumors, and a variety of other conditions. When placed on a heterologous synthetic promoter, the binding site functions as a wild-type p53 response element in either orientation. The analysis examines the impact of socioeconomic, familial, demographic, and household dynamic factors on the three child maltreatment outcomes, and compares the differential impact of these factors across the three types of child maltreatment. The agarose infiltration permitted easy handling of the lung tissue, and maintained lung architecture during cryoprotection. Procedures for HPLC peptide map analysis of recombinant human granulocyte colony stimulating factor include reduction and S-carboxymethylation of the denatured protein, as well as protease digestion with Staphylococcus aureus endoproteinase Glu-C followed by reverse-phase liquid chromatographic separations. A recombinant soluble form of the alpha subunit of the human high-affinity receptor for IgE (rsFc epsilon RI alpha), one of the potent IgE-binding molecules, was tested for its ability to regulate IL-4-induced IgE synthesis by human lymphocytes.
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Overall, the data suggest that an evaluation of the most appropriate correction factor should be applied to each laboratory using their own data collected by their own method in their particular strain of dog. These results suggest that the accumulation of both cathepsins E and D in the regions of selective neuronal vulnerability may be associated with the postischemic development of intense gliosis and also probably neurodegenerative responses. Plasma catecholamine contents were determined and haemodynamic changes were recorded for the detection and quantification of sympathoadrenal responses to the typical points of stimulation (intubation, skin incision, sternotomy). Development of DARPP-32-positive parts of fetal pig ganglionic eminence and ventral mesencephalon in organotypic slice co-cultures. In contrast, eosinophil and neutrophil involvement in urticarial dermographism was minimal. We have previously shown that secretion of TNF protein occurred 2-4 h following incubation of monocytes with L-MTP-PE and that this stimulation of TNF production was associated with an increase in TNF mRNA. Treatment decisions for patients with clinical low volume Stage II NSGCT may be based on cost/benefit and risk/benefit considerations, including relative toxicity, long term cure rate, and individual patient preference. Activin-A binds follistatin and type II receptors through overlapping binding sites: generation of mutants with isolated binding activities. Asymmetric and broad distributions of binding energies were found, with a maximum population peaking at low energy.
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Oxidation of the Birch product yielded the corresponding 17-oxo steroid, which gave the title compound by diborane reduction. Histidine decarboxylase, DOPA decarboxylase, and vesicular monoamine transporter 2 expression in neuroendocrine tumors: immunohistochemical study and gene expression analysis. The low-affinity type-IIb IgG Fc-binding receptors (Fc gamma RIIb) are expressed on B cells. The United States is engaged in comprehensive revisions of the National Primary Drinking Water Regulations. The effects of furosemide on action potentials and responses to several neurotransmitters have been studied in the neurons of Aplysia. Seventy-two patients with a variety of neurologic and ophthalmologic conditions underwent confrontation visual field testing and automated perimetry as a part of their evaluation. No mutation in any of the three MTS1/CDKN2 exons was detected in the other three cell lines by single strand conformational polymorphism analysis. Maximal exercise tests (MET) were performed at the end of each 1-week period, while rest radionuclide ventriculography (RVG) was obtained during 240 mg D and corresponding crossover P.