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Bactricid

Bactricid is a combination of two synthetic (man-made) antibiotics, sulfamethoxazole and trimethoprim. Both drugs reduce the ability of some bacteria to utilize folic acid for growing. Sulfamethoxazole is an anti-bacterial sulfonamide, a sulfa drug.

Other names for this medication:
Adrenol, Assepium, Bactipront, Bactron, Balkatrin, Ciplin, Colizole, Cotribene, Cotrimstada, Cozole, Daiphen, Deprim, Editrim, Epitrim, Esbesul, Escoprim, Fisat, Gentrim, Globaxol, Ifitrim, Ikaprim, Kaftrim, Meprim, Methoxasol, Momentol, Noxaprim, Ribatrim, Roxtrim, Sepmax, Septra, Servitrim, Sitrim, Spectrem, Sulfa, Sulfamethoxazole, Sulfametoxazol, Sulotrim, Sulphax, Sulprim, Sumetoprin, Sumetrolim, Suprim, Suprimass, Trimecor, Trimesulf, Trimosul, Trisolvat, Vanasulf

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Also known as: Trimethoprim

Description

Generic Bactricid is taken to fight against ear infections, urinary tract infections, bronchitis, traveler's diarrhea, Pneumocystis carinii pneumonia. Generic Bactricid works by killing or slowing the growth of sensitive bacteria. Generic Bactricid can't be given to children younger than 2 months old. Bactricid is also known as Co-trimoxazole, Septra, Ciplin, Septrin. Generic names of Generic Bactricid are Sulfamethoxazole, Trimethoprim. Brand names of Generic Bactricid are Bactricid, Bactricid DS, Septra, Septra DS, Sulfatrim Pediatric.

Dosage

This section provides information on the proper use of a number of products that contain sulfamethoxazole and trimethoprim. It may not be specific to Bactrim DS. Please read with care.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

Sulfamethoxazole and trimethoprim combination is best taken with a full glass (8 ounces) of water. Several additional glasses of water should be taken every day, unless otherwise directed by your doctor. Drinking extra water will help to prevent some unwanted effects (eg, crystals in the urine). .

For patients taking the oral liquid, use a specially marked measuring spoon or other device to measure each dose accurately. The average household teaspoon may not hold the right amount of liquid.

To help clear up your infection completely, keep using this medicine for the full time of treatment, even if you begin to feel better after a few days. If you stop taking this medicine too soon, your symptoms may return.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (liquid or tablets): For treatment of bacterial infections: Adults—1 tablet (DS tablet) of 800 milligrams (mg) of sulfamethoxazole and 160 mg of trimethoprim, 2 tablets of 400 mg of sulfamethoxazole and 80 mg of trimethoprim, or 4 teaspoonfuls or 20 milliliters (mL) of oral liquid every 12 hours for 10 to 14 days. Your doctor may adjust this dose if needed. Children 2 months of age and older—Dose is based on body weight and must be determined by your doctor. The usual dose is 40 milligrams (mg) per kilogram of body weight of sulfamethoxazole and 8 milligrams (mg) per kilogram of body weight of trimethoprim, given in two divided doses every 12 hours for 10 days. Weighing 40 kilograms (kg)—4 teaspoonfuls (20 mL) of oral liquid or 2 tablets (or 1 DS tablet) 2 times a day for 10 days. Weighing 30 kg—3 teaspoonfuls (15 mL) of oral liquid or 1 ½ tablet 2 times a day for 10 days. Weighing 20 kg—2 teaspoonfuls (10 mL) of oral liquid or 1 tablet 2 times a day for 10 days. Weighing 10 kg—1 teaspoonful (5 mL) of oral liquid 2 times a day for 10 days. Children younger than 2 months of age—Use is not recommended. For treatment of bronchitis: Adults—1 tablet (DS tablet) of 800 milligrams (mg) of sulfamethoxazole and 160 mg of trimethoprim, 2 tablets of 400 mg of sulfamethoxazole and 80 mg of trimethoprim, or 4 teaspoonfuls or 20 milliliters (mL) of oral liquid every 12 hours for 14 days. Children 2 months of age and older—Use and dose must be determined by your doctor. Children younger than 2 months of age—Use is not recommended. For treatment of Pneumocystis jiroveci pneumonia or Pneumocystis carinii pneumonia (PCP): Adults and children 2 months of age and older—Dose is based on body weight and must be determined by your doctor. The usual dose is 75 to 100 milligrams (mg) per kilogram of body weight of sulfamethoxazole and 15 to 20 milligrams (mg) per kilogram of body weight of trimethoprim each day, given in equally divided doses every 6 hours for 14 to 21 days. Weighing 80 kilograms (kg)—10 teaspoonfuls (50 milliliters (mL)) or 5 tablets (or 2 ½ DS tablets) 4 times a day for 14 to 21 days. Weighing 64 kg—8 teaspoonfuls (40 mL) or 4 tablets (or 2 DS tablets) 4 times a day for 14 to 21 days. Weighing 48 kg—6 teaspoonfuls (30 mL) or 3 tablets (or 1 ½ DS tablets) 4 times a day for 14 to 21 days. Weighing 40 kg—5 teaspoonfuls (25 mL) or 2 ½ tablets 4 times a day for 14 to 21 days. Weighing 32 kg—4 teaspoonfuls (20 mL) or 2 tablets (or 1 DS tablet) 4 times a day for 14 to 21 days. Weighing 24 kg—3 teaspoonfuls (15 mL) or 1 ½ tablets 4 times a day for 14 to 21 days. Weighing 16 kg—2 teaspoonfuls (10 mL) or 1 tablet 4 times a day for 14 to 21 days. Weighing 8 kg—1 teaspoonful (5 mL) 4 times a day for 14 to 21 days. Children younger than 2 months of age—Use is not recommended. For prevention of Pneumocystis jiroveci pneumonia or Pneumocystis carinii pneumonia (PCP): Adults—800 milligrams (mg) of sulfamethoxazole and 160 mg of trimethoprim once a day. Children 2 months of age and older—Dose is based on body size and must be determined by your doctor. The usual dose is 750 mg of sulfamethoxazole and 150 mg of trimethoprim per square meter (m[2]) of body surface each day. This is given in equally divided doses two times a day for 3 days a week on consecutive days (eg, Monday, Tuesday, Wednesday). However, the dose is usually not more than 1600 mg of sulfamethoxazole and 320 mg of trimethoprim per day. Children younger than 2 months of age—Use is not recommended. For treatment of traveler's diarrhea: Adults—1 tablet (DS tablet) of 800 milligrams (mg) of sulfamethoxazole and 160 mg of trimethoprim, 2 tablets of 400 mg of sulfamethoxazole and 80 mg of trimethoprim, or 4 teaspoonfuls or 20 milliliters (mL) of oral liquid every 12 hours for 5 days. Children 2 months of age and older—Use and dose must be determined by your doctor. Children younger than 2 months of age—Use is not recommended.

Overdose

If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe nausea/vomiting/diarrhea, severe dizziness or drowsiness, mental/mood changes.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Side effects

The most common side effects associated with Bactricid are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Bactricid is contraindicated in patients with a known hypersensitivity to trimethoprim or sulfonamides, in patients with a history of drug-induced immune thrombocytopenia with use of trimethoprim and/or sulfonamides, and in patients with documented megaloblastic anemia due to folate deficiency.

Bactricid is contraindicated in pediatric patients less than 2 months of age. Bactricid is also contraindicated in patients with marked hepatic damage or with severe renal insufficiency when renal function status cannot be monitored.

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Transient leukemia with trisomy 21: description of a case and review of the literature. Surgical treatment and course of pulmonary pseudotumor (plasma cell granuloma). Distal movement of the canines was carried out by use of a calibrated sectional archwire exerting an initial retraction force of 200 g. Structures of the N-linked oligosaccharides of the membrane glycoproteins from three lepidopteran cell lines (Sf-21, IZD-Mb-0503, Bm-N). Although body weight was not affected by uranium at any dose, there was a significant (not dose-related) decrease in the pregnancy rate. The chimeric construct is biotinylated by yeast cells in vivo and represents the only biotinylated protein in yeast membranes. The cyanobacterium Synechocystis 6803 was tagged by chromosomal integration of the firefly luciferase gene, luc, resulting in the modified strain Synechocystis 6803-luc. One reason for this difficulty may result from the intricate convergence of both transcriptional and mRNA turnover events which, together, directly influence steady-state mRNA levels. Actinomycosis complicating fibula flap mandible reconstruction: a report of two cases.

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The elimination of theolair drug information activated T cells is important to maintain homeostasis and avoid immunopathology. The binding to Ng-CAM and N-CAM was saturable and in each case Scatchard plots indicated a high affinity binding site with a dissociation constant of approximately 1 nM. Radioimmunolocalization of tumours by external scintigraphy after administration of 131I antibody to human chorionic gonadotrophin: preliminary communication. Activity of the L-arginine/nitric oxide pathway and endothelin-1 in experimental heart failure. We have shown that they can adhere to endothelial cell monolayers, open interendothelial cell junctions, and migrate to the abluminal side when stimulated by a chemoattractant. All cases of histologically proven epithelial malignancy, namely SCC, VC and EQ, were reviewed to confirm the presence of neoplastic changes and ascertain the degree of SCC differentiation. A 2.5-year-old girl with no known medical problems had a witnessed sudden collapse and died.

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The trustworthiness of the stories of elder abuse narrated by district nurses. In the EGF group, total amount of protein was maintained throughout the experimental period, but the HGF groups could not keep the amount of protein of day 1 till day 5. Instead, the human locus syntenic to mouse Dpy19l2 contains a pseudogene, DPY19L2P1. To determine if routine radiological screening is necessary, and if there is a group of children that can safely be managed expectantly. Disruption of mitochondrial calcium homeostasis following chronic doxorubicin administration. Chest pain is moduretic generic name one of the most common presentations in emergency medicine.

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The Id HLH motif is responsible for the inhibitory activity, whereas not much is known about the role of the N- and C-termini. The mouse has become the de facto model for the majority of atherosclerosis studies. Trichomonas vaginalis, an ancient protist, colonizes the vaginal mucosa causing trichomonosis, a vaginitis that sometimes leads to severe health complications. Virtual reality scores were also a combination score derived from summation of various computer-calculated measures of time and accuracy in undertaking two standardized exercises. Anatomical mapping of human herpesvirus reservoirs of infection. Prospective, longitudinal analysis (Canadian Task Force classification II-3). In patients with specific at-risk variants of 2 genes in the leukotriene pathway, DG-031 led to significant and dose-dependent suppression of biomarkers that are associated with increased risk of MI events. Glucose-6-phosphatase activity in the liver of rats on low protein diet. Furthermore, a tentative causal relationship between these two signalling pathways has been indirectly implied derived through the use of inhibitors of tyrosine kinases. Potentials resulting from sacculo-collic reflexes are recorded on the surface of the neck muscles.

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An increase in platelet microparticles was associated with a decrease in the amount of protamine needed to reach the baseline ACT in blood samples removed from the circuit at various bactrim dose based on weight time points during recirculation. To test the efficiency of a microarray chip as a diagnostic tool in a cohort of northwestern European patients with Leber congenital amaurosis (LCA) and to perform a genotype-phenotype analysis in patients in whom pathologic mutations were identified. Diagnostic pitfalls and treatment delays in these patients are discussed. A 26-year-old male presented with increasing dyspnoea and exertional palpitations of 2 months duration. Resolving fetal hyperechogenic lung lesions: an unresolved issue. Successful extracorporeal resuscitation of a probable perioperative anaphylactic shock due to atracurium. The positive correlation to jugular bulb oxygen saturation is somewhat unexpected as rSO2 evaluates regional while SJO2 measures global oxygen content. Some physical and physiological factors controlling the fate of inhaled substances.

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Harmaline was equipotent with harmine but more easily reversible. Using antibodies against variant CD44 (CD44v) sequences, we have examined the expression of variant CD44 glycoproteins on human lymphoid cells and tissues and in colorectal neoplasia. In preparation for human application, the authors determined whether human fetal retinal pigment epithelium (RPE) grafts have a photoreceptor rescue effect in RCS dystrophic rat retinas. After oral administration of SMEDDS capsules and the conventional tablet to fasted Beagle dogs, the Cmax from SMEDDS was greater than that of the conventional tablet. The dynamic characteristics of the rat gracilis anticus muscle at 17.5 degrees C have been determined by isotonic and isometric loading. The dose of cisplatin was not proven to be of significant importance. Thorough examination and investigation of patients with pulsatile tinnitus is stressed. Vaccination of sheep against Schistosoma japonicum with either glutathione S-transferase, keyhole limpet haemocyanin or the freeze/thaw schistosomula/BCG vaccine.

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