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Bacfen (Baclofen)

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Bacfen is a muscle relaxant. It works on the brain and spinal cord to relieve muscle stiffness or spasm maintaining the strength of the muscles. This relieves pain and improves movement of muscles.

Other names for this medication:
Bacfen, Baclof, Baclofen, Bacmax, Chinofen, Liofen, Parafon, Riclofen, Spinofen, Spinospas, Tefsole

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Also known as: Baclofen


Intrathecal baclofen is used to help relax certain muscles in your body. It relieves the spasms, cramping, and tightness of muscles caused by medical problems such as multiple sclerosis, cerebral palsy, or certain injuries to the spine. Intrathecal baclofen does not cure these problems, but it may allow other treatment, such as physical therapy, to be more helpful in improving your condition.

Intrathecal baclofen acts on the central nervous system (CNS) to produce its muscle relaxant effects. Its actions on the CNS may also cause some of the medicine's side effects.

This medicine is delivered by a drug pump directly into the spinal fluid of your back. A doctor will surgically place the pump and monitor the dose of the medication that is delivered by the pump. The dose of intrathecal baclofen will be different for different patients and will depend on the type of muscle tightness that you have.

Intrathecal baclofen is given only by or under the direct supervision of a doctor.


This section provides information on the proper use of a number of products that contain baclofen. It may not be specific to Lioresal. Please read with care.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, or do not take it longer than your doctor ordered.

Measure the oral liquid with a marked measuring spoon, oral syringe, or medicine cup.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For muscle relaxation: For oral dosage form (solution): Adults and children 12 years of age and older—At first, 5 milliliters (mL) three times a day for 3 days. Your doctor may increase your dose by 5 mL every 3 days as needed and tolerated. However, the dose is usually not more than 80 milligrams (mg) per day (20 mg four times a day). Children younger than 12 years of age—Use and dose must be determined by your doctor. For oral dosage form (tablets): Adults and teenagers—At first, 5 milligrams (mg) three times a day. Your doctor may increase your dose by 5 mg every 3 days until the desired response is reached. However, the dose is not more than 80 mg per day. Children—Use and dose must be determined by your doctor.


If you overdose Generic Bacfen and you don't feel good you should visit your doctor or health care provider immediately.


Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Store the oral liquid in the refrigerator. Do not freeze.

Detailed Lioresal dosage information

Side effects

The most common side effects associated with Bacfen are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Development of an in vitro assay for the detection of Botulinum Neurotoxin. Sexual activity during late pregnancy and risk of preterm delivery. Pharmacologic therapy for portal hypertension is effective in the treatment and prevention of hemorrhage from esophagogastric varices. In 10 such flaps performed, one partial necrosis occurred in a patient who was extremely obese and had had a previous laparotomy that may have interfered with the integrity of the underlying blood supply to the rectus abdominis muscle. Post-menopausal women had higher serum PTH and lower bone density of spine and femoral neck than premenopausal women. Expansion of the boundary integral near the locus of traveling instability in a standard reaction-diffusion model proves that the bifurcation is supercritical whenever the spot is stable to splitting.

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Crystal structure of the hydrated strontium salt of methotrexate: two independent molecules with different conformations. Radiation-induced hearing impairment--a pilot study in patients treated for malignant parotid tumours. Rapid determination of urea nitrogen in serum or plasma without deproteinization. Complications following duodenopancreatectomy in chronic pancreatitis. The effects of reduced oxygen concentrations in the gas phase over the culture medium on colony formation and cell proliferation were investigated in high and low cell density primary and secondary cultures of amniotic fluid cells. BYPASS1 negatively regulates a root-derived signal that controls benicar max dosing plant architecture. Community trail development is an emerging strategy to increase physical activity (PA) among community residents. Sarcocystis infections of animals are commonplace and of worldwide distribution. Benchmarking clinical practice quality: an audit of ipsilateral breast tumor recurrence in patients managed for T1/T2 breast carcinoma.

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Tissue factor activity in human monocytes is regulated by plasma: implications for the high and low responder phenomenon. Proceedings: On the role of the beta-hydroxy group of atropine for specificity and duration of the antimuscarinic action. Gut Microbiota Profiling: Metabolomics Based Approach to Unravel Compounds Affecting Human Health. This result was corroborated by experiments in which eye and arm were found to jump always to the same target in the condition that two different targets were presented simultaneously. The microsomal enzyme is inactivated by pre-incubation at 37 degree C, but not a 4 degree C, has an apparent pH optimum of approximately 7.6, and has Km and V values of 270 (microM) and 33.3 (nmol HMG/10 per mg protein), respectively, at 37 degree C. GenomeMixer is a cross-platform application that simulates meiotic recombination events for large and complex multigenerational genetic crosses among sexually reproducing diploid species and outputs simulated progeny to several standard mapping programs. brucei genome, as illustrated by the conservation of syntenic groups of genes in the two stocks, and the polymorphic nature of the genomic regions involved in antigenic variation. The cells mediating this suppression are hapten-specific, H-2-restricted, and possess properties typical of CTL. Intraspinal abnormalities are present in approximately one third of patients with congenital spine deformities. The blood glucose responses to glucagon administration were less than normal in patients with HCC and hypoglycemia and within normal limits in patients with insulinoma.

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Comparative study of the antihyperazotemic activity of the phytopreparations nephroton, canephron and lespenephril. Implanted osmotic minipumps were used to administer submaximal doses of either caerulein or saline to normal rats for up to 4 days. Recent experience suggests that because of the high morbidity associated with these conditions, a very aggressive surgical and medical treatment program is indicated. Seventy-seven pregnancies (79 infants) complicated by hyperthyroidism were seen at three Dublin Maternity Hospitals during a 25 year period. sra5 mutations in Saccharomyces cerevisiae were previously shown to suppress the inefficient growth of ras2 strains on nonfermentable carbon sources and to result in deficient low-Km cyclic AMP (cAMP) phosphodiesterase activity. This article will cover recent developments in preparative SFC for the separation of enantiomers, reviewing several aspects such as instrumentation, chiral stationary phases, mobile phases or purely preparative considerations including overloading, productivity or large scale chromatography. Numerous literature reports describe clinical efficacy of intramuscular vaccinia immune globulin (VIG) for complications of smallpox vaccination, prophylaxis of individuals with contraindications to vaccination, and prevention of smallpox among close contacts of patients with smallpox. The public should be constantly reminded to refrain from consuming raw and inadequately cooked bivalve molluscs all the time, and not just during rocaltrol capsule generic epidemics. Microbiological study of microbial projections during high speed and conventional drilling.

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Induction of transplantation tolerance by allogeneic thymus grafts. Advances in experiences have shifted the choice of anesthesia from general to local anesthesia and sedation for these zithromax z-pak 250 mg tablet patients. The glycosylphosphatidylinositol (GPI)-anchored protein CD59 and the ganglioside GM1 are present on lipid rafts that can be isolated in a detergent-insoluble membrane (DIM) fraction. The practical implication of this study is that recommendations regarding ergonomics for dental professionals may include the use of prismatic glasses, both as primary and secondary prevention of work-related neck pain. Our case illustrates that functional MR cholangiography images can be successfully acquired by using a post-mangafodipir fat-suppressed GRE technique and that bile duct leaks can be detected.

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The results reinforce the usefulness of the multiple causes approach to improve information on mortality and demonstrate important associations, such as hypertension and cerebrovascular diseases, obesity and diabetes or ischemic heart diseases, allowing to plan, prioritize, and reevaluate health actions. OXC (dosage range, 300-1,200 mg/day) was used in monotherapy mometasone topical storage in all of them except for one patient. Since no single histopathological feature is sufficient to discern between a benign and a malignant CLI, the overall balance of clinical, histopathological, immunophenotypic, and molecular features should be considered carefully to establish a diagnosis. Measurement of glycerol turnover by infusion of nonisotopic glycerol in normal and injured subjects. We conclude that the median effective dose from a whole body 18FDG PET/CT in our patients was significantly low. We compared baseline characteristics and outcomes of the AYA population to older patients. This study aimed to examine the involvement of oxidative damage in amphotericin B (AmB) activity against Candida albicans using the superoxide (O2-) generator paraquat (PQ).

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The present goal is to define the cellular basis of autoimmunity through continued immunologic and genetic analysis of this important animal model of human autoimmune disease. However, biopsies taken at various intervals after transplantation showed abundant hybridization with HCMV immediate-early and late gene probes. These abnormalities are features of an insulin resistant-hyperinsulinemic state resulting from abdominal obesity. Some hospitals had no staff members certified to carry out cardiopulmonary resuscitation (CPR). Study of the activity of the nucleolus organizer segments in the chromosomes of normal, leukemic and neoplastic human cells by silver nitrate staining.

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