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Avibru (Ibuprofen)

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Over-the-counter Avibru is used to treat fevers and help with mild aches and pain, including headaches, arthritis, menstrual cramps, toothaches, and backaches. The prescription strength of this medication is used to treat moderate muscle pain, menstrual cramps, osteoarthritis, and rheumatoid arthritis.

Other names for this medication:
Actimol, Alfam, Brudex, Brutiz, Bruzen, Buftiz, Calpol, Cipgesic, Codistar, Diclospas, Dolgesic, Elbugesic, Gesic, Ibifon, Ibruvon, Ibuclin, Ibucon, Ibugin, Ibular, Ibupal, Ibuzen, Inflapen, Lumbril, Methoprofen, Methoriv, Nildol, Oxymark, Oysifen, Proxigesic, Rebufen, Somaflam, Spinach, Subdu, Tabalon, Tidifen, Tizapam, Ultraprin, Xtragesic

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Also known as: Ibuprofen


Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain, and helps to relieve symptoms of arthritis (osteoarthritis, rheumatoid arthritis, or juvenile arthritis), such as inflammation, swelling, stiffness, and joint pain. This medicine does not cure arthritis and will help you only as long as you continue to take it .

In addition, ibuprofen can be used to treat fever, menstrual cramps, and other conditions as determined by your doctor .

This medicine is available both over-the-counter (OTC) and with your doctor's prescription .


This section provides information on the proper use of a number of products that contain ibuprofen. It may not be specific to Children's Motrin. Please read with care.

For safe and effective use of this medicine, do not take more of it, do not take it more often, and do not take it for a longer time than ordered by your doctor. Taking too much of this medicine may increase the chance of unwanted effects, especially in elderly patients .

When used for severe or continuing arthritis, this medicine must be taken regularly as ordered by your doctor in order for it to help you. This medicine usually begins to work within one week, but in severe cases up to two weeks or even longer may pass before you begin to feel better. Also, several weeks may pass before you feel the full effects of this medicine .

To lessen stomach upset, you may take this medicine with food or milk .

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (tablets and suspension): For fever: Children over 2 years of age—Use and dose must be determined by your doctor. Children 6 months of age up to 2 years—Dose is based on body weight and body temperature, and must be determined by your doctor. For fever lower than 102.5 °F (39.2 °C), the dose usually is 5 milligrams (mg) per kilogram (kg) (about 2.2 mg per pound) of body weight. For higher fever, the dose usually is 10 mg per kg (about 4.5 mg per pound) of body weight. The medicine may be given every six to eight hours, as needed, up to 40 mg per kg per day. Infants younger than 6 months of age—Use and dose must be determined by your doctor . For menstrual cramps: Adults—400 milligrams (mg) every four hours, as needed. Children—Use and dose must be determined by your doctor . For mild to moderate pain: Adults and teenagers—400 milligrams (mg) every four to six hours, as needed. Children over 6 months of age—Dose is based on body weight and must be determined by your doctor. The dose usually is 10 milligrams (mg) per kilogram (kg) of body weight every six to eight hours, as needed, up to 40 mg per kg per day. Infants younger than 6 months of age—Use and dose must be determined by your doctor . For osteoarthritis and rheumatoid arthritis: Adults and teenagers—1200 milligrams (mg) up to 3200 mg per day divided into three or four equal doses. Children—Dose is based on body weight and must be determined by your doctor. The dose usually is 30 milligrams (mg) to 40 mg per kilogram (kg) of body weight per day, divided into three or four doses. Infants younger than 6 months of age—Use and dose must be determined by your doctor .


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Motrin Childrens dosage information

Side effects

The most common side effects associated with Avibru are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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The induced resistance was correlated with induction of certain secondary metabolites which may have a role in increasing tolerance in tomato plants to the pathogen. The work makes an evaluation of the benefits brought by the system to the Ambulance Service of the City of Bucharest (ASCB) as well as to those who are using it, and of the conditions that permitted the bringing into operation of the system and made possible work with this system 7 days per week, 24 hours out of 24 for over 4 years. Isolation of Trichophyton simii and Cryptococcus neoformans from soil in India. These changes in fetal adrenal weight were reflected histologically in parallel changes in the size of adrenocortical cells. In addition bills are produced at regular intervals, both for hospitals and for private patients. Obtaining Volar Tilt in Distal Radius Fixation: Use of a Screw as a Proximal Post. Individual hamsters from many of the BIO strains accept MHA skin grafts indefinitely, fail to respond to MHA cells in mixed lymphocyte reactions, and type serologically as identical to MHA. Primary intra-osseous myoepithelioma of phalanx mimicking an enchondroma. The response of MAG gene was delayed by at least 36 hr, and the level of MAG mRNA reached a maximum of approximately 48-fold over the control level on the fourth day in culture.

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The spinal cord and brain stem were treated by Nauta-Gygax method after sacrificing the animals, then the preterminal and terminal degenerations of some ascending spinal systems were analysed. We examined NIS expression in mammary tumors of 14 genetically engineered mouse models to identify genetic manipulations associated with NIS induction. Pituitary apoplexy is a rare cause of sudden and severe headache during pregnancy. Biotin and the biosynthesis of anthraquinoid pigments in Penicillium islandicum Sopp. Studies employing computer-aided, 3D reconstruction of dendritic trees, as well as analysis of a pair of ON DS and ON-OFF DS ganglion cells with overlapping dendritic trees show that the two types of DS ganglion cell partly co-stratify in the middle of sublamina b (stratum 4). Partial characterization of these enzymes revealed their close similarity to the avian smooth muscle phosphatases. Cerebral ischemic injury results in the liberation of heme from degenerating heme-containing proteins. Hapten-specific T cell responses to 4-hydroxy-3-nitrophenyl acetyl. Measuring health-related quality of life in patients with conservatively managed stage 5 chronic kidney disease: limitations of the Medical Outcomes Study Short Form 36: SF-36. Since the binding sites map to regions necessary for transcription of the three adenoviral early genes whose control regions were analyzed, it is likely that the activities play a role in their transcription.

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hematopoietic cells from normal mice with or without serum of normal mice, were conducted. After phase 2 telencephalon and brain stem were analyzed with regard to their contents of serotonin (5-hydroxytryptamine, 5-HT) and 5-hydroxyindoleacetic acid (5-HIAA), the principle metabolite of 5-HT. Pathomorphological characteristics of experimental toxemia induced by thermostable Yersinia pseudotuberculosis toxin. These SAC were found to provide accessory functions irrespective of whether they were syngeneic, semi-syngeneic, or allogeneic to the responding cells. Smoking history can influence the epigenetic and gene expression profile. The purpose of this report is to suggest the usefulness of computed tomography scanning in the evaluation of indeterminate abdominal masses such as the rectus sheath hematoma. Therefore, chymase inhibitors may be useful for preventing cardiovascular diseases and fibrosis via inhibition of angiotensin II formation and transforming growth factor-beta activation. Microfascicular double ligation and interligature heat sealing has been clinically successful in relieving neuroma pain.

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Here, we overview several optical imaging techniques in neuroscience of recent years, including brain clearing, the micro-optical sectioning tomography system, and deep tissue imaging. The studies on the renal effects of the drugs used in premedication were carried out on 27 patients. Increased phosphorylation of dynein IC IC138 correlates with decreases in flagellar microtubule sliding and phototaxis defects. and 80 mg., with respect to its effect on sodium and water excretion. Mechanism of transcription by RNA polymerase II--a molecular basis of regulated gene expression. Differential effects of galanin and neuropeptide Y on extracellular norepinephrine levels in the paraventricular hypothalamic nucleus of the rat: a microdialysis study.

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Comments on the pharmacologic interpretation of the specific and secondary clinical effects of monoamine oxidase inhibitors. Many of the skeletal malformations may be caused secondarily from musculature abnormalities, suggesting that the myotome may be particularly sensitive to the compound. The efficiency of the procedure in removing actin and other contaminating proteins from myosin was demonstrated. In negatively stained preparations purified sarcosyl cores reveal spherical subunits of 21.6-nm diameter in the electron microscope. The bz-s: 2114 (Ac) mutation retains Ac at the original site of insertion, but has lost a 789 bp upstream bz sequence adjacent to the insertion, hence the stable phenotype. Purification of an active protein and production of a monospecific antiserum against it. To avoid costly vendor-specific solutions a DICOM server was implemented in JAVA thereby enabling the data access via internet browser technology. The plasma concentrations of free fatty acids (FFA), glycerol and insulin as well as the blood glucose concentration have been followed in two groups of subjects after infusions of theophyllamine.

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This interaction is unlikely to be mediated by type I luminosity horizontal cells but may be mediated by either direct connexions between cones and rods or by an interneurone with a small receptive field. High sensitivity to autoxidation in neonatal calf erythrocytes: possible mechanism of accelerated cell aging. Fluorescent in situ hybridization of biotinylated ACHE DNA with metaphase chromosomes from human peripheral blood lymphocytes revealed prominent labeling on the 7q22 position. The hybridization of cell DNA with MMTV complementary DNA also did not show detectable amounts of virus-related sequences in the cell genome. The pharmacology of a new short-acting, non-depolarising muscle relaxant steroid (RGH-4201).

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The optimal trading of each discharger, in terms of pollutant reduction load and abatement cost, is greatly influenced by environmental and political factors such as background water quality, the location of river assessment points, and tradable discharge permits. Biochemical determinations consistently showed spontaneous secretion of catecholamines from the cultured cells in the basal state without stimulation. The recessive ataxias are a heterogeneous group of neurodegenerative disorders characterized by cerebellar ataxia associated with a number of different neurologic, ophthalmologic, or general signs. Recent advances in sequencing the human and mouse genomes and the availability of microarray technology and bioinformatic analyses have made elucidating these molecular participants and dialogs a reality. When paired shocks with short intervals were applied, the second spike fractionated at the step to reveal the A and B components. The understanding in discrepancy of alignment in different weight bearing conditions before and after HTO should be considered for the appropriate realignment of the limb. A rapid method for accurate DNA measurements in single cells in situ using a simple microfluorimeter and Hoechst 33258 as a quantitative fluorochrome. Teaching NeuroImages: Painful diplopia and Crohn disease: Think about orbital myositis. Nasal polyp fluid was extracted from 52 patients to evaluate histamine levels and compare them with the corresponding serum levels.

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This is in contrast to the results obtained during immunization by the formaldehyde treated preparation of Mouse Mammary Tumor Virus (MMTV). The onset of acute inflammation occurred 4 days after intraperitoneal injection of bleomycin and reached its peak on the 14th day post-injection. Kaplan-Meier analyses, univariate and multivariate testing were carried out. The integrated genes are arranged in multiple tandem arrays, but the extent of transgene expression does not correlate with copy number nor does it influence the expression of the endogenous neurofilament genes. We studied antigen-specific suppression in NZB and B/W mice to investigate immunoregulatory circuits associated with autoimmune disease. As MR imaging is applied further to cellular and molecular imaging (e.g., imaging of gene transfer and expression), more possibilities for brain tumor diagnosis and treatment will become evident.

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A description and explanation of an unexpected echographic appearance in a patient who had sustained an abdominal shotgun wound is presented. When compared to trypsin both chymotrypsin and carboxypeptidase elicit little relaxation. Our analysis revealed that in the highly conserved amino-terminal domain, all subtype C isolates examined had a methionine-to-leucine substitution at position 8 and most subtype C isolates had an arginine-to-lysine substitution at position 17 of the protein. Needle biopsy of the lung in diffuse parenchymal disease An analysis of 151 cases. The immunosuppressive effect of FK 506 on canine lung transplantation.

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Biochemical differentiation of the Enterobacteriaceae with the aid of lysine-iron-agar. The psychological ramifications of rhinoplasty in transsexuals are discussed. The effect of exposure to heat and cold upon rat brain catecholamine and 5-hydroxytryptamine levels. The mild clinical course of a patient with cystic fibrosis is presented who inherited the two mutations Gly551----Asp and Arg553----Stop in the cystic fibrosis transmembrane conductance regulator gene. Anginex specifically inhibits vascular endothelial cell proliferation and induces apoptosis in these cells, as shown by flow-cytometric detection of sub-diploid cells, TUNEL (terminal deoxyribonucleotidyl transferase-mediated dUTP-nick-end labelling) analysis and cell morphology. Cyclosporin-A prevents endotoxin-induced beta-adrenoceptor impairment in lymphocytes. Combined administration of gigantol and SA synergize to enhance anti-cataract efficacy.

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This study suggests that longtime exposure to high concentrations of aerial ammonia can change fat content in breast muscle, meat quality and palatability via altering expression level of genes participating in important lipid metabolism pathways. The naturally appeared cracking on the human deciduous anterior teeth. PCR primers were designed to cover all the coding regions and flanking intron sequences. Hirsutism, virilism and apparent virilism and their gonadal relationship. Protein microarrays for highly parallel detection and quantitation of specific proteins and antibodies in complex solutions. After drug administration renal venous prostaglandin E decreased in each of eight studies with a mean change from 286 to 141 pg/ml (p less than .001).

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To compare fibrin binding in vivo with that in vitro, Tc-99m-rt-PA binding to fibrin gel in vitro was also imaged. Surgery is always indicated, because benign and malignant tumours in this area cannot be differentiated radiologically. The clinical spectrum of mycosis fungoides in Tanzania, East Africa. Allergic contact dermatitis from nickel in an electrocautery plate. We have evaluated the irritant capacity of 3 different qualities of cocoamidopropylbetaine, using the following method: patch tests have been carried out with 5 different dilutions in 67 patients and the results read at 2 days by noninvasive methods (direct visualization, transepidermal water loss (TEWL), laser Doppler flowmetry (LDF)). This suggests that these mutants are defective in a step in the reaction that precedes the formation of the Holliday intermediate. The putative intracellular mediator diacylglycerol depolarizes membrane potential and causes a decrease in light scatter. After 8 weeks of implantation, the engineered tissues were removed for histological analysis. The recent demonstration that neurons for transplantation can be generated from stem cells and that the adult brain produces new neurons in response to stroke has raised hope for the development of a stem cell therapy for patients affected with this disorder. To the experimental scientist interested in the conformation of macromolecules and in the sensitive response of optical activity to conformational alteration, it offers a relatively new and powerful means of understanding the environment of chromophoric residues.

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After exposure to subinhibitory concentrations as low as one-tenth of the MIC an extended recovery period was observed. The effect of nitroimidazoles on the oxygen consumption rate and respiratory control ratio of beef heart mitochondria. A systematic prospective study of the incidence of cytomegalovirus (CMV) infection during pregnancy and contamination of the neonate was set up in a Maternity Hospital in Lyons. In this study, we studied the involvement of mevalonate derivatives in the regulation of caspase-1 activation. In this review, Erol Fikrig, Fred Kantor, Stephen Barthold and Richard Flavell focus on the use of Borrelia surface antigens as vaccine candidates for Lyme disease. Univariate and multivariate analyses were performed to identify variables associated with outcome. Purification of cellular retinaldehyde-binding protein from bovine retina and retinal pigment epithelium.

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Sequestration in Plasmodium falciparum malaria: sticky cells and sticky problems. They were generalized in the first case and localized on the legs in zyrtec liquid dosage infants the second. High resolution sequencing of HCV and monitoring of innate immune responses at multiple sites across the liver identified a uniform pattern of diversity and argues against viral compartmentalization. Conclusively, our protocol can help to characterize the physiological and pathophysiological relevance of photoreceptor specific proteins and, in principle, should also be transferable to other cell types. This was different for the discrimination between normal and neuropathic MUPs. Model Intercomparison for the Uptake of Organic Chemicals by Plants.

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The development of respiratory motoneurons provides unique data that may be generalized to other mammalian prazosin 1 mg tab motoneuron populations. However, the storage capacity of the entire network then decreases. As such, there has been a recent push to understand the global distribution of OPEs and their behaviour in biota. To examine the correlation between CheA phosphorylation and bacterial chemotaxis, cheA mutations leading to defects in chemotaxis were mapped and characterized. In femoral artery it is compared with the values of the diameter change/pressure change. Alterations of activities of cytosolic phospholipase A2 and arachidonic acid-metabolizing enzymes in di-(2-ethylhexyl)phthalate-induced testicular atrophy.

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Filling of bone defect with blood clot in resections of large cysts (a zone of 2 and more teeth) is ineffective, as it decelerates bone regeneration and leads to relapses in remote periods after surgery. We therefore examined changes in the admission rates for patients with duodenal ulcer and gastric ulcer, both emergency (for haemorrhage, perforation or severe pain) and for elective surgery, before and since the introduction of the new advances in therapy. Thus, it was possible to determine unmistakably the identity and substitution positions (sn-1 or sn-2) for both acyl groups of each PG present in the mixture. In this group we recorded one bladder injury, no cutaneous nerve injuries, and one recurrence. Study of the therapeutic use of inhibitors of AA metabolism, penicillin, and TT showed that lipoxygenase products may be more important in the pathogenesis of OM than the cyclo-oxygenase products, and that the use of a combination of penicillin and corticosteroid produces the best results. Patients were qualified for permanent stimulation when showing a reduction of at least 50 percent in incontinence episodes or days. These experiments suggest that neither acute nor chronic delta 9-THC produce specific effects on the repeated acquisition of serial position responses in pigeons. The approach also provides a framework for subsequent statistical (Bayesian or other) analysis of efficacy, cost effectiveness, and impact on clinical practice and health care delivery. These antibodies decorate in immunofluorescence microscopy arrays of bundles of intermediate sized filaments present in established epithelial cell lines growing in culture. The aim of this study was the evaluation of the effect of Okra (Abelmoscus esculentus) on blood levels of glucose in diabetes.

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The distribution of the target antigens, therefore, fits the known distribution of the products of HLA-D. The critical period for developmental plasticity of descending spinal axons extends to postnatal day 26, although axons which grow through the lesion site become fewer in number and more restricted as to origin with increasing age. We review the relevance of autophagy to the diagnosis and clinical management of esophageal diseases with the following questions in mind. The in vitro folding pathway of bovine pancreatic trypsin inhibitor (BPTI) has been described previously in terms of the disulfide-bonded intermediates that accumulate during folding of the protein. DNase I footprinting shows that the TFOs we designed can form a sequence-specific triplex with the target. Anaphylactic, anaphylactoid, and related forms of shock are true medical emergencies characterized by bronchial reactivity, airway edema, and hypovolemia. To determine the role of the GPI anchor in cell activation, we transfected EL-4 murine thymoma cells with cDNA encoding either DAF or a transmembrane form of DAF (DAF-TM). The research presented here examines the adjuvant activity of LCP. 125I-labelled asialofetuin injected intravenously into chars (Salmo alpinus L.) was cleared from the blood with a half-time of approx.

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Melanin content and telomerase activity were phenotypically not related to invasiveness in these three mouse melanoma cell lines. The effect of lactulose and lactitol administration on fecal fat excretion in patients with liver cirrhosis. We report a study of sodium/potassium-adenosine triphosphatase in erythrocyte membranes of 59 patients with pregnancy-induced hypertension and 48 normotensive pregnant controls. Proband 1, a type II PC defect, harbored a compound heterozygous mutation, p.Arg194Cys/Gly324Ser in the PROC gene, underwent two thromboembolic events. The uptake of 67Ga by tumor cells was dependent upon the concentration of transferrin in the medium, which apparently plays a role as one of the pathways of tumor accumulation of 67Ga. Reduction of myocardial infarct size in rats by a selective 5-lipoxygenase inhibitor (AA-861). Their vasoconstrictor activities were found to be about 80 times less than that of ANG I, and were not altered by the CEI enalaprilat, indicating that tonin-like enzymes do not play a role in the generation of ANG II by the arterial wall. Reaction of striated fibers of human skeletal muscles to long-term anti-orthostatic hypokinesia. During a maxolon dose 3-week period the structure of the thylakoid system did not perceivably change, with the exception that large plastoglobules formed in the stroma.

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A prospective, randomized trial of early versus late benicar reviews administration of a single dose of surfactant-TA. This peptide caused only a moderate inhibition in visceral muscle assays. The increase in cytoplasmic RNA content in the principal cells of the ipsi- and contralateral parts of this nucleus relative to the stimulated ear in the case of monaural stimulation and the increase in RNA content in response to binaural stimulation suggests a uniform distribution of bilaterally converging connections from the lower nuclei of the auditory system on the principal cells. Simultaneous technetium-99 MAG(3), iodine-131-orthoiodohippurate and iodine-125 iothalamate clearance and biodistribution after bolus injection in rats. Clinical experiences with ampicillin-cloxacillin combination for oral use (Viccillin S Meiji). 1966.-Earlier studies demonstrating that staphylococcal alpha-toxin and streptolysin S have the capacity to lyse protoplasts and spheroplasts of certain species of bacteria and Mycoplasma have been extended to encompass additional kinds of wall-less bacteria including L forms. In these patients GAT intervention improve their clinical outcome and the efficiency of hospital admission. The study suggests that zimelidine has a favourable effect on mild, moderate, and even in some severe phobic conditions. Three lysosomotropic agents NH4Cl, chloroquine and methylamine which were previously demonstrated to inhibit the degradation of the hormone-receptor complex after its internalization (down-regulation) did not prevent the initiation of casein synthesis, of lactose synthetase activity and of DNA synthesis.

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Modulation of the immune response by plasma protease inhibitors. Comprehensive diagnostic approaches to tumor metastases in the skeleton. Within the department of restorative dentistry the phantom-course seems to be especially suited to make use of these didactic means. Variegated aneuploidy related to premature centromere division (PCD) is expressed in vivo and is how often can you take zofran 4 mg while pregnant a cancer-prone disease. In 1998, the International Breast Cancer Screening Network (IBSN) sponsored an assessment of quality assurance policies and practices to define their scope for population-based screening mammography programmes across IBSN countries.

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