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Avanafil

Avanafil is used to treat erectile dysfunction (ED: impotence; inability to get or keep an erection in men). Avanafil is in a class of medications called phosphodiesterase (PDE) inhibitors. It works by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection.

Other names for this medication:
Avanafil, Spedra, Stendra

Similar Products:
Ativan, Risperdal, Strattera, Atarax, Aldactone, Revia, Priligy, Alprostadil

Description

Avanafil is FDA-approved anti-impotence drug manufactured by Sunrise Remedies. The active ingredient of Avanafil is Avanafilfil, which is classified as PDE5 inhibitor and is aimed to treat male sexual dysfunction. Other well-known agents share a similar mechanism of action as Avanafilfil: Tadalafil (Cialis), Sildenafil (Viagra) and Vardenafil (Levitra). Once a drug is absorbed into the bloodstream, Avanafilfil expands muscles in the walls of blood vessels, thereby increases blood flow into the penis and provides a strong erection. The effect of medication starts in 15-30 minutes after taking and can last up to 6 hours, allowing you to choose the most appropriate time for you and your partner. Avanafilfil helps to achieve an erection when sexual stimulation occurs. Avanafil doesn't protect you and your partner from sexually transmitted diseases (including HIV) and from pregnancy. Avanafil is not intended for the treatment in women and children.

Dosage

Take one pill orally with a full glass of water 15-30 minutes before sexual activity. It may be taken with or without food. Start with 50 mg, if you are undergoing stable alpha-blocker therapy or have other health issues. You should not take the medication more than once a day or more than a recommended dose.

Overdose

If an overdose occurs and you are not feeling well, you should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Avanafil are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Avanafil if you are allergic to Avanafil's components. Do not take Avanafil if you are also using organic nitrates, nitrate drug for chest pain or heart condition (e.g., nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate), nitrates as amyl nitrate or nitrite ("poppers"). Do not take Avanafil if you take other medication to treat erectile dysfunction, pulmonary arterial hypertension, such as riociguat (Adempas). Do not take Avanafil in case you are taking erythromycin, medicines called alpha-blockers, ketoconazole, itraconazole (Sporanox or Nizoral), ritonavir (Norvir) or indinavir (Crixivan). Try not to consume alcohol while using Avanafil, as it can lower your blood pressure, causing dizziness and rapid heart rate (tachycardia). Do not drive or operate machinery while taking the medication. Contact you doctor or health care professional right away if the erection lasts longer than 4 hours or if it becomes painful. Avanafil does not protect you and your partner from sexually transmitted diseases and pregnancy. Avanafil can be dangerous for children and women.

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Contribution to the histological and histochemical study of seborrheic verruca (basocellular papilloma). Healthy monozygous twins do not recognize identical T cell epitopes on the myelin basic protein autoantigen. To address this question, PAM-3, a soluble bifunctional protein, was modified by addition of the KDEL endoplasmic reticulum (ER) retention/retrieval signal to its COOH terminus. The movement disorders were produced in rats by intraperitoneal administration of iminodipropionitrile (IDPN) in the dose of 100 mg/kg per day for 12 days. Airway assessment was performed independently by a resident and a licensed anesthesiologist or certified anesthetist with the modified Mallampati Score. The results showed that adding Etanidazole to conventional RT produced no global benefit for patients who had advanced head and neck carcinomas. However, sensitivity and specificity are suboptimal, especially at the intermediate levels between 4.1 and 10.0 ng/ml (monoclonal). The surgical causes for the development of retinal detachment in experimental vitrectomy. All tested rickettsial SFG Armenian isolates from Dermacentor marginatus were identified as R. The diagnosis of the malformations was performed by computerized tomography (CT) in a few patients and by magnetic resonance (MR) in most cases.

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The quantitative histochemistry of supramedullary neurons of puffer fishes. The role of the capsaicin receptor TRPV1 and acid-sensing ion channels (ASICS) in proton sensitivity of subpopulations of primary nociceptive neurons in rats and mice. Dogs may recover from clinical rabies and may then intermittently excrete virus in the saliva. For fibre isolation, low-temperature incineration of lung tissue was used. Direct characterization of the folded, unfolded and urea-denatured states of the C-terminal domain of the ribosomal protein L9.

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