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Atroact (Atorvastatin)
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Atroact

Atroact belongs to a group of drugs called HMG CoA reductase inhibitors, or "statins." Atroact is used to treat high cholesterol, and to lower the risk of stroke, heart attack, or other heart complications in people with type 2 diabetes, coronary heart disease, or other risk factors.

Other names for this medication:
Anzitor, Ateroz, Atocor, Atorin, Atoris, Atorsan, Atorva, Atorvastatina, Atorvin, Atorvox, Atova, Atroact, Avascare, Biger, Biostatina, Cardyl, Cardyn, Danelip, Delipost, Divastin, Finlipol, Larus, Lipicon, Lipitaksin, Lipivastin, Lipobi, Liponorm, Liporest, Lipostop, Liprimar, Locol, Lorvaten, Sortis, Stator, Tarimyl, Taven, Torvacard, Torvazin, Totalip, Tulip, Vasolip, Vastatin, Vastina, Voredanin, Zarator, Zoamco

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Also known as: Atorvastatin

Description

Lipitor (atorvastatin) belongs to a group of drugs called HMG CoA reductase inhibitors, or "statins."

Lipitor is used together with diet to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL), to increase levels of "good" cholesterol (high-density lipoprotein, or HDL), and to lower triglycerides (a type of fat in the blood).

Lipitor is used to treat high cholesterol, and to lower the risk of stroke, heart attack, or other heart complications in people with type 2 diabetes, coronary heart disease, or other risk factors such as genetically high cholesterol.

Lipitor is for use in adults and children who are at least 10 years old.

Dosage

Take Lipitor exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Lipitor is usually taken once a day, with or without food. Take the medicine at the same time each day.

Do not break an Lipitor tablet before taking it, unless your doctor has told you to.

You may need to stop using this medicine for a short time if you have:

uncontrolled seizures; an electrolyte imbalance (such as high or low potassium levels in your blood); severely low blood pressure; a severe infection or illness; or surgery or a medical emergency.

It may take up to 2 weeks before your cholesterol levels improve, and you may need frequent blood test. Even if you have no symptoms, tests can help your doctor determine if Lipitor is effective.

Lipitor is only part of a complete treatment program that may also include diet, exercise, and weight control. Follow your doctor's instructions very closely.

Store at room temperature away from moisture, heat, and light.

Detailed Lipitor dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 20 to 25 degrees C (68 to 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Atroact are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Lipitor if you are allergic to atorvastatin, or if you have:

liver disease; or if you are pregnant or breastfeeding.

Atorvastatin can harm an unborn baby or cause birth defects. Do not use if you are pregnant. Stop taking Lipitor and tell your doctor right away if you become pregnant. Use effective birth control to prevent pregnancy while you are taking this medicine.

Atorvastatin may pass into breast milk and could harm a nursing baby. Do not breastfeed while you are taking Lipitor.

To make sure this medicine is safe for you, tell your doctor if you have ever had:

liver problems; muscle pain or weakness; kidney disease; diabetes; a thyroid disorder; or if you drink more than 2 alcoholic beverages daily.

Lipitor can cause the breakdown of muscle tissue, which can lead to kidney failure. This happens more often in women, in older adults, or people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid).

Atorvastatin is not approved for use by anyone younger than 10 years old.

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Clinical effectiveness and tolerance of loratadine versus cetirizine in the treatment of seasonal allergic rhinitis. The authors can conclude that the checklist can be a valuable tool in a review process that culminates in review by an experienced clinician. Nutrition assistance programs for the elderly should reexamine their effectiveness in preventing nutritional deficits in older disabled women. Third, peaking at approximately 520 ms, evaluative differentiation of ingroup and outgroup members occurred, with greater ingroup bias displayed by those with higher levels of prejudice on an explicit measure. This antibiotic had a disruptive effect on membrane permeability as evidenced by the loss of intracellular potassium immediately after exposure to the drug. CABG as compared with PCI was associated with better 10-year survival in patients with multivessel coronary artery disease.

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Cold adaptation changed the mitochondrial response to short-term hypothermia and subsequent warming up. Informed consent in oral and maxillofacial surgery: a study of its efficacy. The study suggests that this effect can be maintained with repeated injections for up to at least three treatment cycles, with duration of effect per cycle of between 12 and 20 weeks. Whenever arrhythmias had started they continued as long as noradrenaline was infused. Role of beta blockers as the only therapy for preparing the hyperthyroid patient for surgery. Both methods are specific when used to determine CPIB levels in normal sera from laboratory animals or humans treated with clofibrate (Atromid-S). Excitability and depolarization-release characteristics of excitatory nerve terminals in a tail muscle of spiny lobster. gorilla NA and comparisons of antibody titres of human sera with EBNA, H. After four weeks of active treatment and a second two-week washout period, patients received the alternative antihypertensive agent under the same procedure and time schedule as in the first treatment phase. The study demonstrated the role of wild murine rodents in selection of different strains of tick-borne encephalitis and Powassan viruses, determined their ecological characteristics reflected in the epidemiological features of tick-borne encephalitis and Powassan encephalitis in southern Far East.

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Immunocytochemical localization of enkephalin and substance P in retina and eyestalk neurones of lobster. LEU3 of Saccharomyces cerevisiae encodes a factor for control of RNA levels of a group of leucine-specific genes. They also have a distinct pattern of distribution, both in the brain and the gastrointestinal tract, compatible with a role mediating, with CRF, the response to stress. This study assesses associations between HL measures (word recognition, numeracy, and conceptual knowledge) and signs of periodontal disease. The early results from this study were better than a previously treated historical control series and justify evaluation of adjuvant chemotherapy with MTX in a prospectively randomized trial. In contrast, inhaled CO (50, 250, and 500 ppm) had no effect on U-46619-induced pulmonary vasoconstriction before or during administration of BAY 41-2272. Bone formation starts not from implanted embryonic fragments, but in intact periosteum and endosteum containing cambial cells of the osteodifferon.

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Effect of intestinal resection in dogs on different digestive parameters. Norepinephrine (NE) increased in hypothalamus at the 1st day, the 2nd day and the 7th day after noise exposure, and increased in striatum at the 7th day after noise exposure, in cortex at the 4th day and the 7th day after exposure. Using the Constant score preoperatively and 6 months after surgery the functional status of the treated shoulder was evaluated. These cortices form a caudomedial promontory that is located between the posterior cingulate and prestriate areas. Superoxide anion release was suppressed at days 5 and 7 after treatment, but returned to control levels by day 14. In the present study, we observed that the HBx and HBc genes significantly down-regulated MICA expression. Distribution of injury and microdosimetry of ozone in the ventilatory unit of the rat. pylori infection in gastric cancer and was also strongly correlated with positive vascular invasion, which was an independent prognostic factor for poorer survival in this study. To extract Gd from tissues and facilitate its release, chelation therapy should be both safe and effective.

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Furthermore, in contrast to the heparin-released proteoglycan, the detergent-extracted proteoglycan is able to bind detergent micelles, shows affinity for the hydrophobic gel octyl-Sepharose, and can be inserted into liposomes. These findings underscore the specificity of capsaicin treatment for substance P containing nerves. In addition to standard full anticoagulation with heparin, the Cardial inferior vena cava filter was introduced percutaneously under local anaesthesia through the unaffected contralateral femoral vein and positioned in the inferior cava below the renal veins. These were prepared by chemically modifying amylose or cellulose before dyeing, to increase solubility. Use of this test for determination of GBS colonization during labor is highly sensitive and specific and may lead to a further reduction in rates of neonatal GBS disease.

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The main findings in the acute stage after SAH were represented by a marked increase of c-AMP and 5 HIAA values, whereas HVA levels were only slightly higher. Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance. Flat adenomas identified in the National Polyp Study cohort at baseline were not associated with a higher risk for high-grade dysplasia initially, or for advanced adenomas at surveillance. Progression of the disease ceased in 27 patients for varying periods, with a mean of two years. In the former group unilateral resection was done, whilst the latter group had bilateral resection of the thyroid gland. Worsening fluid retention in a patient with hereditary angioedema and end-stage renal disease.

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And during the follow-up period of 5 or 6 years, both patients acquired full recovery without clinical complications. The regional effects of two mutants in Drosophila analyzed by means of mosaics. The disadvantages of epidural anesthesia in patients with coronary artery disease are also well known, however, rarely reported. The effects of substance P (SP) in rat spinal cord on the humoral immune response to sheep red blood cells (SRBC) were investigated by the hemolytic plaque-forming cell (PFC) technique. In COPD patients, the results of isolated low-to-moderate intensity cycle ergometer training are not comparable to effects of multimodality and high-intensity training programs. These groups are modified during the postsynthetic modification of acid phosphatase and are probably connected with the process of bonding and splitting of mannose 6-phosphate and N-acetylglucosamine, in agreement with previous biochemical models for the intracellular transport of newly synthesized lysosomal hydrolases to lysosomes. An in vitro study of the peroxyl and hydroxyl radical scavenging capacity of the calcium antagonist amlodipine. Computer-assisted 3-dimensional modelling of polyetheretherketone (PEEK) was recently introduced for cranial reconstruction. From 1950s to 1980s, the average age at the detection of silicosis increased from 41.3 to 52.7 and the average survival time of silicosis patients prolonged from 2.0 to 12.2 years.

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This suggests that hourly changes in Ang II concentrations and/or in Ang II receptor density after short-term administration of the angiotensin-converting enzyme (ACE) inhibitor cilazapril does not significantly affect renal vascular reactivity. Lithium and the converting enzyme inhibitor: a dangerous combination. Patients with poorly differentiated malignancies showed impaired monocyte chemotactic responsiveness and low numbers of tumor-infiltrating macrophages. Demographic processes and the role of medical science and public health in improving the demographic composition. Sex Hormone-Binding Globulin (SHBG), the plasma carrier for both estradiol and androgens, inhibits the estradiol-induced growth of MCF-7 cells (estrogen-dependent breast cancer cells), through its membrane receptor (SHBG-R), cAMP and PKA. Additional BALB/c mouse brains were also positive at 8, 12, and 17 months after infection. Using a previously developed probabilistic formulation of additive clustering, the Bayesian Information Criterion is proposed for this role, and its application demonstrated. Results show data collected for points in lakes and rivers in the northeast of Brazil. It appears that the postoperative intraocular conditions and functional results are better when drainage is not performed. Bidirectional effects of chronic treatment with agonists and inverse agonists at the benzodiazepine receptor.

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Association of a structured transthyretin denaturation intermediate is sufficient for amyloid fibril formation in vitro. Optimal turning of critically ill patients is not well established. In the present study, we further characterized the ERK signaling pathway in pancreatic tumor cell lines in order to determine whether the ERK pathway is subject to a compensatory downregulation. None of the measured parameters corresponded with clinical effect. The median follow-up period was 36 months (range, 12-48 months). Acetylcholinesterase and aminopeptidase assays produced multiple peaks of activity. Amylase secretion by infusions of pilocarpine and parasympathetic nerve stimulation was low, but regularly higher in response to pilocarpine than to parasympathetic nerve stimulation. XII: Requirement of mRNA (AUG codon) for Met-tRNA Met f binding to 40S ribosomes.

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The systematic evaluation and management of chronic and recurrent pain in children with juvenile rheumatoid arthritis (JRA) is only in the beginning stages of empirical development. This effect seems to be related to increased synthesis of prostaglandins, for it disappears partially after pretreatment with acetylsalicylic acid, which alone has no effect on the spontaneous activity of mice. Fusarium infection initially presented with pyomyositis in one patient and with embolic skin lesions in another following T cell-depleted BMT. In vitro, IFN-gamma also reduced endothelial barrier (monolayer electrical resistance, increased albumin permeability) and reduced tight junction (occludin) expression and staining. Gene analysis of genomic DNA from stored serum by polymerase chain reaction: identification of three missense mutations in patients with cholinesterasemia and ABO genotyping.

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The antibodies were directed against four major protein antigens of M. Her consciousness improved by intravenous administration of high-dose methylprednisolone together with other combination therapies. DNA analysis of hepatocellular carcinoma and clinicopathologic implications. Hospitals have seen a tremendous increase in the number of surgical procedures performed in the outpatient setting. The highest mortality (55-70 per cent) is observed in the tetanuses of the third group. the initial dye concentration and the addition of sodium carbonate and sodium chloride. Paraffin-embedded clinical specimens from five pathologic stages of breast tumorigenesis and from normal breast tissue were used.

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Our study was aimed at investigation of electrocardiographic abnormalities in chronic pulmonary obstructive disease and asthma and to assess the relationship of the extent of airway obstruction to the frequency of ECG changes. Biosynthesis of the ethyl side chain of stigmasterol derivatives by the slime mould Dictyostelium discoideum. The proportion of job applications containing at least one application from established principals, proportion of principals appointed as new partners, incentives and disincentives to changing partnership. Hybridization showed that the three clones each contained one single region which is complementary to U2 RNA. The projection of the retina onto the optic tectum of the pigeon has been investigated using elavil pill images silver impregnation methods for degenerating axons and terminals, autoradiographic tracing, and the Golgi methods. Fifteen patients with evidence of excessive systemic vasoconstriction following cardiac operations were studied. simulans mosaic females (heterozygous for Mos) were crossed with non-mosaic males, two distinct classes of mosaic offspring occurred, one resulting from a maternal effect in which the non-Mos offspring were nevertheless mosaic. Twenty-four refrigeration trials at temperatures ranging from minus 13 degrees C to minus 195.8 degrees C were carried out on trichinous porcine meat samples ranging in size from 120 gm to 11 kg. The patient was treated by surgical excision and showed no signs of recurrence over a follow-up period of 12 months. Under these circumstances the animals produce both anti-DNP-PLL antibodies and antibodies directed against the conveyor albumin.

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This is the first time that a membrane-integrated carotenogenic enzyme has been purified and finally obtained in an active state. Replication of the picornaviruses is thus entirely dependent upon the proteolysis of viral precursor proteins. A three-dimensional representation of linear growth and skeletal maturation. Four primer pairs derived from gag and one from pol were used in amplification of reverse-transcribed total RNA prepared from peripheral blood mononuclear cells of seven blood donors. Blastic reaction in the regional lymph nodes evoked by xenogeneic second-set grafts.

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Isolation of a Bacillus subtilis transformant producing thermostable alpha-amylase by DNA from a thermophilic bacterium. In examining this protein we found that the putative caspase 9 interaction domain is a surprisingly weak inhibitor and is also conformationally unstable. The report is expected to contribute towards the establishment of a rational, efficient and standardized fumigation programme for SPF animal facilities, under increasing constraints of safety and environmental considerations concerning pollution with toxic and corrosive agents. In this study, we report the expression of the Ke 6 protein in normal male reproductive tissues by immunofluorescent staining. As main criteria of the maturation the RNA-content and the activity of PPase has been tested. Distribution of labeled cells was plotted using a drawing apparatus.

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This article addresses a specific adjuvant approach to immunotherapy in which highly active immunostimulatory phosphorothioate oligodeoxyribonucleotide moieties are linked to the principal allergenic moiety of a relevant aeroallergen. A method was devised to study the bond strength of direct-bonding orthodontic adhesives. Expression of CD45RA was significantly reduced in both frequency and intensity in LPL, and LPL had significantly reduced percentages of CD11a/CD18 and CD29 positive cells compared with PBL. While exogenous SCF induced clonogenic growth of all primary AML samples clozapine agranulocytosis dose dependent investigated, TNF-alpha failed to stimulate leukemic cells to proliferate. In general, the data collected during the first and second trial were used for exploratory and confirmatory analysis, respectively. To describe the glycaemic status (assessed by an oral glucose tolerance test (OGTT)) and associated comorbidities in a cohort of Australian children and adolescents at risk of insulin resistance and impaired glucose homeostasis (IGH). Prospective observational and interventional trials are required to better define perioperative management. In several sww mutants, a portion of the bcd mRNA population becomes concentrated at the posterior pole of the oocyte during late oogenesis. The role of peripheral catecholaminergic system in the mechanism of stress-protective effects of neuropeptides is discussed. 6) It was argued that the relation between S-32 uptake by the matrix of the osteoid and chondrocytes as functional cells should be studied in relation to the role played by cartilage tissue in the mechanism of ossification.

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The analysis favors a so-called R2 or more extensive resection for cancers invading beyond the submucosa. Two mg/kg of morphine (or 10 or 20 mg/kg given orall) was recognized as saline. Experimental cerebral vasospasm in cats: modification by a new synthetic vasodilator YC-93. Atropine, tripelennamine, and propranolol did not alter the vasodilation. The interrelationship between the activity of proteolytic enzymes (BAPAases) from buckwheat and rye seeds hydrolyzing Nalpha-benzoyl-DL-arginine-p-nitroanilide (BAPA) and the amount of the antiserum to these enzymes necessary to obtain a certain inhibition level has been studied at different stages of seed germination. The assay involves the oxidation of thioguanine with potassium permanganate to a fluorescent product.

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The internal thoracic artery and its branches after coronary artery anastomoses in pediatric patients. Modified hemoglobin solution as possible perfusate relevant to organ transplantation. Open trial of a sleep health promotion program for college students. Tumours induced by DMH in the colonic mucosa increased in size during the experiment. Adenovirus-mediated gene delivery to cells of the magnocellular hypothalamo-neurohypophyseal system. The roles of macrophages and the complement system as potential host defence mechanisms in mice against campylobacter infection were studied in vivo, by depleting the murine serum-complement or the phagocytic cells. It is concluded that oxidation products of sodium sorbate that possess genotoxic and cell-transforming properties are formed under conditions of heating, sonication and storage. A gene encoding a protein kinase was identified by homology-based PCR amplification in Encephalitozoon intestinalis, a microsporidian parasite pathogenic to humans, and its orthologue has been identified by database mining in the genome of the related species E. Based on the LHH for the pooled analysis at week 1, droxidopa is 7.8 times more likely than placebo to show a clinical benefit than result in discontinuation because of an AE. Effect of the protease inhibitor contrical on oxidative phosphorylation and proteolysis in kidney under thermal ischemia.

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Studies on the origin and evolution of life provide a reasonable explanation for the prominent presence of this unruly class of chemical reactions. In the present contemporaneous cohort of BC patients with BMs, the NTX response at 3 months was strongly associated with survival. Development of a mutant of Dictyostelium discoideum, HG403, is described whose cells spread strongly on a substratum. In addition, ligation of alphavbeta3 resulted in a significant increase in cell surface-associated plasmin levels, which coincided with a 2- to 3-fold increase in cell invasion as measured in the Matrigel invasion assay. In contrast, for the gut, net uptake of SDMA was found, which was lower in LPS rats.

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Previous studies on stamen development mainly focused on single gene functions by genetic methods or gene expression changes using comparative transcriptomic approaches, especially in model plants such as Arabidopsis thaliana However, studies on Arabidopsis anther protein expression and post-translational modifications are still lacking. A significant increase in the baseline concentration of SP-LIR and beta E-LIR was seen in BAL of allergic subjects. Therapeutic gap when it comes to behavioral symptoms and psychoses among the elderly. The mechanisms that determine whether a precursor cell re-enters the cell cycle or exits and differentiates are crucial in determining the types and numbers of cells that constitute a particular organ. The predicted amino acid sequence of the ltdh gene product has significant similarities to a family of short-chain dehydrogenases, enzymes that are involved in several oxido-reduction reactions in a wide range of organisms. The first enzyme of creatine biosynthesis, L-arginine:glycine amidinotransferase, occurs in the kidney and produces guanidinoacetate, which is released into the renal vein. Extensive sequence divergence between the reference genomes of two elite indica rice varieties Zhenshan 97 and Minghui 63. A stable tendency to a lower seroquel xr quetiapine 50 mg reproduction of population during the studied period has been detected in Tatarstan, both for the entire Republic and for the urban and rural population separately. In this report we discuss the diagnostic and therapeutic management of a patient in whom the parasitic nature of cholangitis was underestimated due to the small size and site of the cyst, and to the misleading concomitant presence of cholelithiasis.

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Localization of a repressive sequence contributing to B-cell specificity in the immunoglobulin heavy-chain enhancer. The des-amino ethidium analog exhibits fluorescence quenching upon binding, consistent with less efficient quenching of the chromophore through interactions with solvent than within the intercalation site. Although the febrile response was smaller in aged female rabbits, there was no decline in CRP or leukocyte responses, an observation that was not predicted. noroxin medication coli enables this organism to convert the cis-diol intermediate to catechol. We propose that such distinct distributions of each IF protein reflect functional differences during early development. Plateletpheresis using the same machines and techniques but without HES was the control. All of these damages combined with an additional metabolically induced decreased convulsive threshold could provoke convulsions. This salt-habituated form can be restored to a near-normal growth rate by adding yeast extract, RNA or RNA-hydrolysates, but not by DNA or its hydrolysate.

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Virus-induced interferon alone (25,000 U/day) delayed tumor development and increased survival time noroxin tabletas 400 mg . The profiles of histamine release in sites challenged with compound 48/80 were significantly different in the groups with CIU and CIUR. These methods supplement each other to enable long-term monitoring of physiological effects and of effects with special local characteristics. An open-label, non-randomized, two-period, sequential clinical trial was conducted as follows: during Period I (Reference), each volunteer received a single oral dose of 25 mg atomoxetine, whilst during Period II (Test), a combination of 25 mg atomoxetine and 300 mg bupropion was administered to all volunteers, after a pretreatment regimen with bupropion for 7 days. coli pangenome remains unexplored and the relative importance of mutation and selection acting on core genes and strain-specific genes is unknown. The regulation of this experimentaly induced autoantibody was studied by examining the ability of male and female (NZB x NZW)F1 mice to generate antigen-specific suppressor cells. The appearance of these plasmids in the population requires intact insA and insB reading frames, but not insC. Treatment of infected tibial fractures and pseudarthrosis using an external fixator. Movement of calcium ions and release of histamine from rat mast cells.

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