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Ativan (Lorazepam)

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Lorazepam, sold under the brand name Ativan among others, is a benzodiazepine medication. It is used to treat anxiety disorders, trouble sleeping, active seizures including status epilepticus, alcohol withdrawal, and chemotherapy induced nausea and vomiting, as well as for surgery to interfere with memory formation and to sedate those who are being mechanically ventilated. While it can be used for severe agitation, midazolam is usually preferred. It is also used, along with other treatments, for acute coronary syndrome due to cocaine use. It can be given by mouth or as an injection into a muscle or vein. When given by injection onset of effects is between one and thirty minutes and effects last for up to a day.

Other names for this medication:
Almazine, Anxilor, Anxionil, Anxipose, Atipam, Biokalm, Biolar, Calmese, Dulozep, Larosh, Larpose, Lopam, Lopez, Loracalm, Lorakar, Loralite, Lorazam, Lorazepam, Lorazine, Loricon, Loripam, Lorivan, Lorpam, Lorvin, Lotweet, Nexlor, Norpose, Olraz, Trapex, Urpam, Zelor, Zepatrac, Zepnap

Similar Products:
Zyloprim, Zofran, Provera, Thorazine, Ambien, Xalatan

Also known as: Lorazepam


Ativan tablets should be taken in the way your doctor prescribed them. Don’t take more or less Ativan than prescribed without first talking with your doctor.


Ativan is usually taken two or three times daily. These doses are usually spread out at equal intervals. However, when Ativan is used for insomnia, it’s usually taken just once at bedtime.

Taking Ativan with food

You can take Ativan with or without food. If it upsets your stomach, try taking it with food to help decrease this side effect.

Can Ativan be crushed?

Yes, Ativan can be crushed. Some Ativan tablets may also be split. If you’d like to split your tablets, ask your pharmacist if it’s safe to do so.


Take Ativan exactly as it was prescribed for you. Follow all directions on your prescription label. Never use Ativan in larger amounts, or for longer than prescribed. Tell your doctor if the medicine seems to stop working as well in treating your symptoms.

Lorazepam may be habit-forming. Never share Ativan with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.

Misuse of habit-forming medicine can cause addiction, overdose, or death. Selling or giving away Ativan is against the law. Ativan should be used for only a short time. Do not take this medicine for longer than your doctor recommends.

Do not stop using Ativan suddenly or you could have unpleasant withdrawal symptoms, including a seizure (convulsions). Ask your doctor how to safely stop using this medicine. Call your doctor if this medicine seems to stop working as well in treating your anxiety symptoms.


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Ativan can be fatal. Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, fainting, or coma.


Store Ativan at room temperature away from moisture, heat, and light.

Keep track of the amount of medicine used from each new bottle. Ativan is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Side effects

The most common side effects associated with Ativan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Ativan if you have:

narrow-angle glaucoma; or a history of allergic reaction to any benzodiazepine (lorazepam, alprazolam, diazepam, Ativan, Klonopin, Restoril, Tranxene, Valium, Versed, Xanax, and others).

To make sure Ativan is safe for you, tell your doctor if you have::

breathing problems such as COPD (chronic obstructive pulmonary disease) or sleep apnea (breathing that stops during sleep); drug or alcohol addiction; depression, mood problems, or suicidal thoughts or behavior; kidney or liver disease; seizures; or glaucoma.

Tell your doctor if you are pregnant or plan to become pregnant. Lorazepam may harm an unborn baby. Avoid taking this medicine during the first trimester of pregnancy.

If you use Ativan while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

If you are breastfeeding, tell your doctor if you notice drowsiness or fussiness in the nursing baby.

Ativan is not approved for use by anyone younger than 12 years old.

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HRCT is superior to chest radiography as an indicator for the risk of infection in these patients. Stone analysis is not useful in the routine investigation of renal stone disease. The pharmacognostical identification of Panax quinquefolius was carried out. Errors were classified according to proximal cause and underlying systems failure by multidisciplinary teams of physicians, nurses, pharmacists, and systems analysts. Successful steroid pulse treatment in childhood acquired haemophilia with nephrotic syndrome. Effect of neptazane on intra-ocular pressure in relation to its systemic action and its clinical application. The patient returned 1 week later with spontaneous expulsion of the ectopic pregnancy associated with profuse hemorrhage.

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These results demonstrate that asbestos and H2O2 activate AP-1-dependent gene transcription. This paper describes a patient with malignant limb-girdle muscular dystrophy with complete deficiency of adhalin (50 kDa dystrophin-associated glycoprotein (DAG)) in skeletal muscle. In the case of fused silica test mass, instabilities can be minimized but not eliminated. Baseline PAEE predicts a change in FM in younger adults, who as a group gained weight in this study. Third, the MPD technology is essentially linear over six to seven orders of magnitude, i.e., it is possible to accurately quantify radiolabeled proteins over a range from at least 60 zeptomoles to 60 femtomoles. Lepechinia urbaniana was investigated with respect to abietane diterpenes. There was no significant difference between the Jiang component-treated and the Infected group. Furthermore, the analysis demonstrated that whether the twins were monozygotic or dizygotic had no impact on the results. Cervical anastomoses have a higher leak rate than thoracic anastomoses, but leaks from thoracic anastomoses are more morbid.

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In VLBWI, expression of TLR4 surface protein, detected by flow cytometry, and TLR4-specific mRNA, quantified by real time-PCR, were significantly reduced in comparison to mature infants and to adults. This case is one of the few in which disseminated histoplasmosis occurred as the first manifestation of AIDS in a patient in a nonendemic area. The personnel of the Zadar Veterinary Stations were not able to provide information since blood samples from the suspected animals were not taken. Long-term result of lumbar disk chemonucleolysis (a 8-12 years follow-up). Regulation of non-hepatocyte acute phase phenomena has not been delineated as thoroughly, but clearly involves a number of inflammation-associated cytokines.

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An implantable radiation dosimeter has been developed to monitor dose delivered at depth in patients undergoing external beam therapy. Altered vascular reactivity of rats with adrenal-regeneration hypertension. Chiral N-salicylidene vanadyl carboxylate-catalyzed enantioselective aerobic oxidation of alpha-hydroxy esters and amides. Bilateral carotid angiograms revealed extravasation in the extradural spaces. Predominant expression of human zic in cerebellar granule cell lineage and medulloblastoma. In the identification of proteins using peptide mass fingerprinting, samples are enzymatically digested and resolved into a number of peptides, whose masses are determined and matched with a sequence data-base. Rheological parameters, which reflect the behavior of red blood cells (RBC), were correlated with the alteration in PE/PS ratio in these cells. SLE patients with a high IFNalpha score had a significantly higher prevalence of renal disease, a greater number of American College of Rheumatology criteria for SLE, and a higher Systemic Lupus International Collaborating Clinics damage index (SDI) score than did SLE patients with low IFNalpha scores.

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This may prevent unnecessary surgery with attendant morbidity and mortality. We describe the use of a gene-targeted random epitope library for the mapping of antigenic determinants. This approach allows the joint study of multiple markers within a gene by considering haplotypes and grouping them in nested clades. In addition, we found that the microbiological contamination of mice and rats in conventional facilities was severe. There were too few women using OCs containing gestodene or norgestimate to draw substantial conclusions. Intrapleural topical application of cisplatin with the surgical carrier Vivostat increases the local drug concentration in an immune-competent rat model with malignant pleuromesothelioma.

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The inhibitory action of paraquat could be antagonized by superoxide dismutase but not by catalase and indomethacin. Ventilatory responses to exercise in adults after repair of tetralogy of Fallot. The lower size limit of detectability of an isolated egg bed is about 0.5 m with a 400-kHz sidescan sonar used with a 50-m range when towed at 3 knots. campestris, the adaptative capacity of the organism to vinasse was demonstrated. Midazolam, propofol, and clonidine for sedation and control of autonomic dysfunction in severe generalized tetanus. The results strongly suggested the formation of such hydroperoxide even in biological Maillard reaction termed as glycation, and implied its contribution in pathogenesis and oxidative lesions associated with hyperglycemia. Among patients who had had diabetes for more than 4.5 years (the shortest duration at which microvascular complications were noted), 82 of 169 had joint limitation. Tetracycline eye ointment or lid rotation was applied according to trachoma grade. PTHrP produces the same effect on renal and osteoblast membrane in vitro and on calcium and inorganic phosphate fluxes in vivo as human PTH.

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This study examined the seasonal variation in plasma concentrations of T(4) in juvenile American alligators (Alligator mississippiensis) from three populations in central Florida, USA. Tobacco smoking and blood coagulation: acute effect on plasma stypven time. The kinetics, proliferative and differentiative potential of stem hemopoietic cells (CFUs) and productivity of hemopoietic tissues were significantly influenced by dose rate, absorbed dose and degree of suppresssion of bone marrow functions. All ESTR studies to date have shown untargeted mutations that occur at much higher frequencies than predicted. The early diagnosis of kidney failure in diabetic patients and the new developments in its treatment. The purpose of this study was to elucidate the clinical and histopathologic features of this distinctive lesion. Mesenchymal tissue labelled mainly for type I and III interstitial collagen and fibronectin.

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Adverse reactions in blood donors with a history of seizures or epilepsy. The best crystals diffract strongly to 4.8 A Bragg spacings, which is the maximum resolution to which we can measure data with the detectors available, suggesting that useful diffraction extends well beyond this. The upstream region of the SP-B gene: intrinsic promoter activity and glucocorticoid responsiveness related to a new DNA-binding protein. Phosphorylation of the tumor suppressor protein p53 by mitogen-activated protein kinases. Our results indicate the potential of gene expression profile analysis for elucidating mechanism of action of genotoxic agents. These ulcers resemble human gastric ulcers that penetrate the muscularis mucosa. These men were extensively screened for cardiovascular risk factors in the period 1972-1974. Identification of a major gene responsible for type 1 diabetes in the Komeda diabetes-prone rat. With adequate rehabilitation, most patients can return to enjoyable, productive lives.

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In response to membrane depolarization, voltage-gated ion channels undergo a structural rearrangement that moves charges or dipoles in the membrane electric field and opens the channel-conducting pathway. Because expression of PSA is under direct hormonal influence, however, ADT can decrease the serum PSA value independent of antitumorigenic activity. Experimental teratoid of the tests of white mice induced by testosterone and copper sulfate. These pK values reflect the ionization properties of a catalytically essential group, which is tentatively considered to be either the H2O/OH- ligand binding to the catalytic zinc atom or a histidine residue. Effect of vasoactive drugs on gastric blood flow measured by a cross thermocouple method in rats. Since the use of PD98059 reduced the frequency and amplitude of bladder contractions, ERK inhibitors may provide a new therapeutic approach to the treatment of bladder overactivity after spinal injuries. Prenatal alcohol exposure had a significant negative impact on several developmental indices, including grip strength and negative geotaxis. We found a marked decrease in receptor number in placentas corresponding to small for gestational age infants (S.G.A.) in relation to preterm and full-term adequate for gestational age (A.G.A.).

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Evidence for two types of firing pattern during the sleep-waking cycle in the reticular thalamic nucleus of the cat. On a method of rapid staining of preparations obtained with the freezing microtome. Calphostin C is a potent and specific inhibitor of protein kinase C (PKC). The goal of this work was to provide an in vitro model to mimic the in vivo response of astrocytes to nerve injury and to find ways to modulate this response and create a milieu that favors astrocyte migration and repopulation of the injury site. The amino-terminal extremity of the human immunodeficiency virus type 1 transmembrane protein (gp41) is thought to play a pivotal role in the fusion of virus membranes with the plasma membrane of the target cell and in syncytium formation. A personal case, subsequently controlled neroptically and histologically, is then described. Eleven cases were associated with cerebral arterial infarction, nine with cerebral haemorrhage and one with venous infarction. Converging studies suggest it requires cytoplasmic dynein, cell polarity genes, and microtubule-associated proteins that coordinate microtubule remodeling.

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Fifteen days after initiating of dialysis subfebrile fever was developed, followed within 2 days with a left hemiparesis. An elevated level of maternal serum alpha-fetoprotein was found in the case with normal karyotype. However, the correct diagnosis can be made by standard ECG methods. Further research is needed to establish the effects of larger and longer lasting interventions. Antagonism of the intracellular action of botulinum neurotoxin type A with monoclonal antibodies that map to light-chain epitopes. Susceptibility of baboon (Papio doguera) kidney cells to human enteroviruses. The experimental setup accomplishes the coherent summation of two orthogonally polarized TEM01 and TEM10 beams that are obtained from the transformation of a TEM00 beam by use of a simple binary diffractive optical element. State of sensitivity of some pathogenic and potentially pathogenic bacterial species to antibiotics in Czechoslovakia. We present here microwave-based modifications of standard protein assays that dramatically reduce the time required to determine protein concentrations. To facilitate diagnosis during the early stages of disease, when often not all clinical symptoms are manifest, a good serological marker is needed.

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DNA repair and apoptosis are increasingly recognized as important processes involved in resistance to chemotherapy. The study cohort consisted of 2 groups: 19 patients who were randomly assigned to receive LT4 therapy, titrated to maintain a normal serum thyrotropin level (main group), and 14 patients who did not receive any LT4 replacement therapy (control group). Statistical analysis was conducted with the use of chi2, population-attributable risk, and logistic regression. The effects observed are similar to those found for liposomes modified with linear poly(ethylene glycol). Study of the sorption capacity of red blood cell membranes for the assessment of the pattern of endogenous intoxication in dermatoses. The exact number of genes involved could not be determined, because different genetic models could be proposed for each location and no common genetic solution could be given. Eight patients had achieved full erections and vaginal penetrations without noteworthy complications during the follow-up period. Protein kinase X (PrKX), karyotypically located on the human X chromosome, is a type I cAMP-dependent protein kinase.

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The Bax/Bcl-2 ratios supported the finding and time course of apoptosis, whereas TUNEL staining of cardiac tissue sections identified sporadic apoptotic ventricular cells. Perceptions of a medical microbiology service: a survey of laboratory users. The measurements are done with a conductive atomic force microscope (AFM) using various techniques. The careful selection of patients with an appropriate indication for the procedure is a preferred alternative to its improper and indiscriminate use. Arm crank exercise with static leg FNS in persons with spinal cord injury.

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The discovery of novel regulatory mechanisms for AC5 and AC6 and their potential role in crucial physiological processes provide new avenues for research into therapeutic interventions targeting the cyclic AMP pathway. Attempts are made to analyze the functional form of the phase boundaries in order to understand the transition mechanism between different phases. This test for characterizing the MDR1 expression offers high sensitivity and specificity and is therefore of great clinical relevance. Work over the past decade has shown that they are part of an evolutionarily conserved PAR-aPKC system involved avanafil tablets in cell polarity in various biological contexts. Reduced cell spreading and motility could not be accounted for by preferential association of beta 1B with a given integrin alpha subunit.

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Using bisulfite modification and a methylation-specific PCR, we examined the methylation status of the COX-2 promoter in primary tumors from 110 breast cancer patients. Theoretically, transmyocardial laser revascularization allows direct perfusion of the ischemic area as ventricular blood flows through the channels to the myocardium. In this review, we first summarise how the yeast homologs were identified and characterised. The mobile phase is composed of an aqueous solution containing 35 g/l of sodium sulphate, 1 g/l of sodium 1-octanesulfonate, 14 ml/l of tetrahydrofuran (THF) and 50 ml/l of 0.2 M phosphate buffer pH 3.0. glabrata isolates during treatment of a critically ill liver transplant recipient. Effect of unilateral nephrectomy on elimination of gentamicin in rabbits.

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Similar trends were observed for red blood cells and the hematocrit values. Randomized multi-institutional trials are needed to verify the encouraging results of recent phase 2 trials. This is a case report of chylous ascites caused by performing para-aortic lymph node dissection for a patient with cervical cancer. Excellent physical characteristics of technetium and vantin antibiotic class slow washout of Tc-99m sestamibi made possible clear delineation of mediastinal parathyroid adenomas by Tc-99m sestamibi imaging. The level of serum zinc was determined before and after treatment.

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Desmin sequence elements regulating skeletal muscle-specific expression in transgenic mice. Dairy farm effluent effects on urine patch nitrous oxide and carbon dioxide emissions. 3D spectrum imaging of multi-wall carbon nanotube coupled pi-surface modes utilising electron energy-loss spectra acquired using a STEM/Enfina system. Significant activation of caspase-12, -3 and -7 contributed to cell apoptosis and severe ischemic injury was shown after 7 h of preservation by UW solution with insulin. A lentivirus/VSV pseudotyped virus, which does not require replicating cells for integration of its genome, efficiently transduced a high proportion of human PBLs with chTCRs against CEA. Tumorigenicity and immune response to syngeneic rat cells transformed with virions and isolated transforming fragment of adenovirus 12 DNA. No significant abnormalities were observed in the test animals and in particular no EMS-like conditions. Effect of lung inflation on levator veli palatini muscle altace 5 mg activity. Six patients with Japanese encephalitis, four males and two females whose age ranged between 2 and 47 years, were subjected to neurophysiological and radiological studies. Mean lobar Qs/Qt, calculated using blood samples from lobar veins at thoracotomy on day 3, was markedly increased in the pneumonia lobe (0.69) compared with the contralateral lower lobe (0.08), and alveolar ventilation of that lobe approached zero.

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A novel, high-sensitivity diagnostic x-ray spectrometry (DXS) method was used for the fast, noninvasive analysis of Pt in external tissues of patients with cancer treated with courses of cDDP. The diagnostic proficiency of nuclear medicine professionals and the accuracy of equipment may be tested with phantoms. In renal arteries, LPS also induces mRNA expression of all chemokines and cytokines investigated with the exception of IL-6. Because human HDACs are targets for cancer therapy, these findings have significant implications in cancer treatment. Candida species are considered as the most important fungal human pathogens, causing a variety of clinical entities, ranging from superficial, noroxin brand name cutaneous-mucosal to deep-seated and disseminated infections. The identification and binding characteristics of endothelin-1 and endothelin-3 and their ETA and ETB receptor subtypes in cultured adult rat cardiac fibroblasts represented study objectives. The rigid layer (peptidoglycan) of the wall of the chemolithotroph Ferrobacillus ferrooxidans was isolated after various chemical treatments.

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Plasma levels of 1,3,5(10)-estratriene-3,17-beta-diol and 3,17-beta-dihydroxy-delta 1,3,5(10)-estratriene-16-one. Radiographs showed a destructive osteoblastic tumor of the mandible that was proven by biopsy to be osteosarcoma. Supraspinous ligament also indicated to resist in extension slightly, whereas the facet capsules did not. Clinical features and radiological, anatomopathological and therapeutic characteristics of the tumors were retrospectively studied. fastidiosa genome that contains a 28-nucleotide insertion, and single base changes that distinguish CVC and grape X.

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Two phantoms were immersed in normal saline and examined with the same technique to evaluate the thickness of the sonographic interface between water and phantoms. Dose adjustment was done in TCI group whereas the other groups received standard doses. Changes in the amino acid sequence of the coat protein readthrough domain of potato leafroll luteovirus affect the formation of an epitope and aphid transmission. The formal equivalence of high ionic strength and high electrolyte dielectric constant is demonstrated. Molecular diagnostic techniques have led to the recent identification of several new coronaviruses and a respiratory parvovirus. Indeed, they produced an inhibition of cell proliferation and arrested the cell cycle specifically in the G2/M phase. After they can i take zyrtec d while breastfeeding were killed, four-millimeter-wide strips of bone taken from the anterior, medial, posterior, and lateral quadrants of the central femoral diaphysis were subjected to four-point bending tests to failure. They discuss the effects of a secondary bone graft consisting of a compact bone. Activated human T cells express class II molecules, but their capacity to present soluble antigens and stimulate T cells has been repeatedly questioned.

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The Yae antibody recognized in vitro-synthesized ITF-1, a third E2A (Pan) gene product also produced by the mechanism of alternative RNA splicing, but did not recognize the related HLH proteins, ITF-2, REB alpha, or REB beta. All published controlled studies concerning SLIT-swallow were analysed to evaluate AE rates. Rhamnolipid biosurfactant is shown to be approximately 9 times more effective than the structurally similar synthetic anionic surfactant ABS in solubilizing hydrocarbon into the aqueous phase. The proposed approaches are applied to two microarray datasets and compared to other well-known gene selection methods using codes available from the second author. Luciferase expression was decreased exponentially over a 24-day period after which point luciferase activity could no longer be detected. Moreover, both agents can be combined in a single inhaler, and provide patients with a more convenient and effective way in which to deliver treatment to the endobronchial tree. A potent human interleukin-4 antagonist stimulates the proliferation of murine cells expressing the human interleukin-4 binding chain. Since dirithromycin is at least as well tolerated as erythromycin, with its convenient administration schedule and pharmacokinetic profile it is a useful alternative to erythromycin in the treatment of appropriate community-acquired infections. The prevalence of allergic rhinitis is increasing in many countries. We describe a modification of the biceps femoris myocutaneous flap for reconstruction of ischial pressure ulcer defects.

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Generation and characterization of a novel hematopoietic progenitor cell line with DC differentiation potential. Large differences in the sex ratio of mortality exist among the studied populations. The first part describes methods of determination of serum and urine concentrations. Moreover, cells expressing activated mutant Mpl receptors were tumorigenic in transplanted mice. typhimurium TA100 for alpha-dicarbonyl compounds as a proof of the mutagenic mechanism. Conflicting data have been reported regarding the expression of galectin-3 during carcinogenesis in the colon. The first is what is the maximum daily dose of glyburide antigen specific and is mediated by the interaction between the T-cell receptor (TCR) and antigen bound to the major histocompatibility complex (MHC).

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