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Local application of botulinum toxin Type A, which results in muscle inactivity but not in tissue degeneration, however, did not induce tenascin expression 12 h to 12 days post-injection. Dexamethasone inhibits the release of TSH from the rat anterior pituitary gland in vitro by mechanisms dependent on de novo protein synthesis and lipocortin 1. RARE-sequences help to shorten investigation time, particularly in cases involving the skeleton. With recent improvements in sequencing and immunoblotting technology, detection of significantly smaller amounts of protein has become necessary. Phylloplanins of tobacco are defensive proteins deployed on aerial surfaces by short glandular trichomes.
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As part of a study of the psychosocial impact of HIV infection in women, 23 HIV seropositive and 23 seronegative women were asked about their experience of being tested for HIV. The diagnosis of haemoglobinopathies is of growing importance in Norway because of increasing immigration from countries where haemoglobinopathies are prevalent conditions. Studies designed to investigate the ultrastructure of the connective tissue matrix have historically relied on chemical fixatives to stabilize tissue microarchitecture. Postoperative depression of cellular immunity, assayed by the lymphocyte blastogenic response to phytohemagglutinin, was significantly correlated with the amount of surgical trauma and did not correlate with blood transfusions and corticosteroid administrations, nor with the duration of anesthesia. Experimental study on measles virus 6th report: fundamental investigation for practical application of vaccine manufactured by the mouse-fixed measles virus. This study attempted to develop and test a method of rapid assessment of coverage by using the existing resources of the program. Abundant NPFFir cells and fibers were demonstrated in the spinal cord. To investigate a local production of IgE in intestine, we analysed the levels of transcripts for epsilon germ-line (epsilonGT), and potential regulators of IgE production, IL-4, IL-13, IFN-gamma, IL-4Ralpha, STAT6 and FcepsilonRIalpha in intestinal mucosa of adult patients with FA. 14-3-3epsilon is consistently found to be upregulated in the sun-protected dermis of aged skin, by Western blotting and immunohistochemical staining.
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Early and intensive treatment of lupus nephritis with pulse cyclophosphamide. This article proposes clear lens extraction and intraocular lens (IOL) implantation for the correction of high hyperopia. Paper chromatographic separation of thiocyanate is the first step in determining non-bound thiocyanate in homogenized animal and vegetable foods and in human serum. Antagonism of the nitric oxide synthase inhibitor, L-NAME, of the effects of phencyclidine on latent inhibition in taste aversion conditioning. To assess the feasibility of a study design that may determine whether subcutaneous administration of the interleukin-2 receptor antibody daclizumab can safely reduce the dependence on standard systemic corticosteroids or other immunosuppressive regimens in patients with sight-threatening, noninfectious intermediate uveitis, posterior uveitis, or panuveitis. Evaluation of the prognostic value of pepsinogen C was performed retrospectively in corresponding patients by multivariate analysis that took into account conventional prognostic factors. We evaluated GAPDH gene expression by real time RT PCR in breast (MCF-7 and T47D) and prostate (PC3 and DU-145) cancer cell lines treated with amino and non-amino bisphosphonates. Lability of regulatory systems as a component of mobilizational readiness in sports. As expected, perceived balance capabilities were more strongly related to current behavior (frequency of doing specific activities) than to past experience (fall history). Four dogs previously had been diagnosed and treated (three with intramuscular DOCP, one with oral fludrocortisone acetate).
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Initial symptoms are similar to acute pharyngitis or laryngitis but could end in fulminant course that could be life threatening. This study examines the role of digital subtraction magnetic resonance imaging (MRI) of the breast in the interpretation of the morphology and characteristics of breast disease. They have various cardiac and vascular protective effects, but the relevant mechanisms of action in these areas remain to be fully understood. To evaluate the importance of the position of the halogen atom in iodinated DNA-binding bibenzimidazoles, with respect to sensitization of UV-A-induced DNA breakage. Neoplastic cells in Antoni A type areas sometimes showed cord-like outgrowths or a neurofibromatous pattern. On the dynamics of epiletic seizures in tumors of the cerebral hemispheres. Characterization and isolation of the chloroplast protein import machinery.
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Cycloheximide and actinomycin D pretreatment did not prevent ECM-induced down-regulation of PSA mRNA, while actinomycin D-treated cells on plastic maintained stable PSA mRNA levels. An unusual complication of intra-osseous infusion during paediatric resuscitation. Gamma interferon (IFN-gamma), a macrophage-activating cytokine, modulates gene expression through the activity of a transcription factor designated IFN-gamma activation factor (GAF). Postoperative computed tomography scans clearly show that the position of implants is sometimes far from ideal. Significance of discharge from the nipple in nonpuerperal mammary conditions. Intestinal parasitism in a group of mental patients during seven years of observation. Rickettsia felis, the agent of an emerging infectious disease: Report of a new case in Mexico. Here we report that IL-6 stimulated different patterns of tyrosine phosphorylation of JAK-TYK kinases in IL-6-responsive murine (B9E and T10D) and human (ANBL-6 and OCI-My4) plasma cell tumor lines.
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Inhibition of in vitro diphenylhydantoin hydroxylation by different anticonvulsant drug combinations: a kinetic analysis. Fibrosis was seen as a reaction to the iron followed by severe atrophy of affected structures. Soluble receptors for VEGF were employed as competitive inhibitors to determine the contribution of the growth factor to the hypoxia-stimulated mitogen production. Exogenous stable expression of CD30 in Rat-1 cells constitutively activated NF-kappaB. These results point to a new approach for noninvasive diagnostic monitoring through quantitation of fluorescent lifetime, tau, when the lifetime of the fluorophore is comparable with photon migration times. Level of modernization may be a useful concept for understanding differences in rates of depression in different parts of the world. After the termination of the stress procedure, hippocampal glutamate concentrations continued to rise in the aged rats, reaching a level approximately five times higher than the young rats, and remained elevated for at least 2 h after termination of the stress. Antioxidant activity of reduced plastoquinone in chloroplast thylakoid membranes.
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The analysis of the pregnancy and mode of delivery, development of disease, diagnostic and therapeutic method. MAO inhibition and control of anxiety following amitriptyline therapy. The discovery and characterization of the RANKL/RANK/OPG signaling pathway and the identification of its role in the pathogenesis of bone loss have provided the rationale for the development of drugs with the ability to modulate RANK-induced osteoclastogenesis. A significant elevation of GAP-43 mRNA level was observed 2 weeks after the transection in dexamethasone treated animals. The set of antigens was shown to be almost identical in the causative agents of glanders, melioidosis, as well as in B. These findings confirm and extend recent reports that the inferior frontal gyrus is vital for mediating response inhibition. At the fine structural level, microperoxisomes measured 150-175 nm in diameter in controls and in group 1 and 2. The effects on the contents of norepinephrine (NE), dopamine (DA) and serotonin (5-HT) in the brain and on the levels of their metabolites both in the brain and urine were also assessed.
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In light of the current status of research, several priorities are identified that include expanding the range of research questions asked about treatment, evaluating a broader range of treatments, examining long-term treatment effects, bridging research and practice, extending treatment further to underserved and understudied populations, and integrating developmental theory and research into child treatment research. These observations suggest that protein introns may perform a function for their host, rather than being just selfish elements. These results are important for the use of the poliovirus replicons as a recombinant vaccine vector. The effects of hormonal changes during the menstrual cycle and of oral contraceptives on the EEG, heart-rate and a number of performance tasks were investigated in 16 female subjects (Ss). Chronic instability of the ulnar collateral ligament of the metacarpophalangeal joint of the thumb can cause significant functional disability due to pain and weakness of pinch and grasp. The amino acid composition of the diet ingested by reference and cafeteria diet-fed rats has been analyzed in Wistar rats from day 30 to 60 after birth. Mutations in the GDD1 gene cause gnathodiaphyseal dysplasia, a rare human skeletal syndrome with autosomal dominant inheritance. Two of these three patients are alive (31 and 49 months, respectively) and well at this report, with one of them being repeatedly experiencing disease remission with the use of simple salvage chemotherapeutic regimens. The plasma levels of heparin did not differ whether given concomitantly with DHE or not.
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Timescales of population rarity and commonness in random environments. CM-ext (200 or 500 mg/kg, p.o.) inhibited an increase in vascular permeability in mice induced by acetic acid, and reduced acute paw edema in rats induced by compound 48/80 or carrageenin. In normal rats, NPSF demonstrated weak intrinsic activity but sub-effective doses of the peptide significantly increased the magnitude and duration of spinal morphine anti-nociception in both tests. This enhancement was observed for both disulfide- and nondisulfide-bonded proteins. We conclude from these data: 1) Intrapreoptically applied beta-END inhibits LH release only in the absence of steroids. These 5 family physicians performed a similar number of obstetric procedures compared with their Obstetrics and Gynecology resident counterparts, and they performed as well as their family medicine resident counterparts on national in-service examinations. The binomial distribution and the evidence for independent action of ion channels. The results demonstrate that these polyclonal antisera also recognize epitopes shared with other proteins synthesized in culture by skin fibroblasts. As a side issue, we observed that a cysteine point mutant designed for X-ray analysis crystallized mainly as a symmetric dimer around an intermolecular disulfide bridge formed by the newly introduced cysteine. Recent studies showed that nonnucleoside reverse transcriptase inhibitors (NNRTIs) have variable effects on dimerization of p66 and p51 subunits of HIV-1 reverse transcriptase (RT).
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Optical maps are assembled to cover the whole genome, and the accuracy of assembly is critical. On the basis of evidence collected from the literature, we propose a general model by which protein kinase (PK) A and the different PKC isoforms can inversely affect cell growth. Serotypes of salmonella at Ibadan, Nigeria, with special note of the new serotypes isolated in Nigeria. The diagnosis was suspected by echo-Doppler and confirmed by arteriography, allowing percutaneous embolization in the same session. Thus, the effect of host immune surveillance on surface residues is similar. The data also suggest that terminal differentiation of epidermal cells might be a specialized form of apoptosis.