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Arpicin (Aripiprazole)

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Arpicin is a medication that works in the brain to treat schizophrenia. It is also known as a second generation antipsychotic (SGA) or atypical antipsychotic. Arpicin rebalances dopamine and serotonin to improve thinking, mood, and behavior.

Other names for this medication:
Apicord, Aridus, Arifril, Arilan, Arinex, Aripat, Aripicon, Aripiprazole, Aripra, Arpicin, Asprito, Biliff, Elrip, Pipra, Rizotal, Schizopra

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Also known as: Aripiprazole


The Abilify Maintena brand of aripiprazole is used to treat schizophrenia and bipolar I disorder (manic depression) in adults. The Aristada brand of Abilify Maintena is for use only in treating schizophrenia in adults.


This section provides information on the proper use of a number of products that contain aripiprazole. It may not be specific to Abilify Discmelt. Please read with care.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not open the blister pack that contains the tablet until you are ready to take it. Remove the tablet from the blister pack by peeling back the foil, then taking the tablet out. Do not push the tablet through the foil. Do not break or split the tablet. Place the tablet in your mouth. It should melt quickly. After the tablet has melted, you may swallow or take a sip of water.

Swallow the tablets whole. Do not break, crush, or chew them.

Abilify Mycite® has a sensor in the tablet, which helps track it inside the stomach or bowels. The Abilify Mycite® System comes with a patch (wearable sensor), a smartphone application (app), and a web-based portal. Follow your doctor's instructions on how to use the medicine.

The Abilify Mycite® tablet is usually detected within 30 minutes after you take it, but there may be a delay of more than 2 hours for the smartphone app and web portal to detect that you have taken the medicine, and sometimes it might not be detected at all.

To apply the Abilify Mycite® patch:

The app will tell you when to apply or remove the patch. It should be changed weekly or sooner as needed. Place the patch to the left side of your body just above the lower edge of your rib cage. Do not put the patch in areas where the skin is scraped, cracked, inflamed, or irritated, or near the area where you had removed the previous patch. The app will help you place the patch in the correct location. You may keep the patch on when showering, swimming, or exercising.

Aripiprazole may be taken with or without food. If your doctor tells you to take it a certain way, follow your doctor's instructions.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (tablets and orally disintegrating tablets): For bipolar mania: Abilify® and Abilify Discmelt®: Adults—At first, 15 milligrams (mg) once a day. When it is given with lithium or valproate, the starting dose is 10 to 15 mg once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 30 mg per day. Children 10 years of age and older—At first, 2 mg once a day. The dose will be gradually increased to 10 mg once a day. Your doctor may adjust your dose again as needed. However, the dose is usually not more than 30 mg per day. Children younger than 10 years of age—Use and dose must be determined by your doctor. Abilify Mycite®: Adults—At first, 15 milligrams (mg) once a day. When it is given with lithium or valproate, the starting dose is 10 to 15 mg once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 30 mg per day. Children—Use and dose must be determined by your doctor. For depression: Adults—At first, 2 to 5 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 15 mg per day. Children—Use and dose must be determined by your doctor. For irritability in children with autistic disorder: Children 6 to 17 years of age—At first, 2 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 15 mg per day. Children younger than 6 years of age—Use and dose must be determined by your doctor. For schizophrenia: Abilify® and Abilify Discmelt®: Adults—At first, 10 to 15 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 30 mg per day. Children 13 to 17 years of age—At first, 2 mg once a day. The dose will be gradually increased to 10 mg once a day. Your doctor may adjust your dose again as needed. However, the dose is usually not more than 30 mg per day. Children younger than 13 years of age—Use and dose must be determined by your doctor. Abilify Mycite®: Adults—At first, 10 to 15 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 30 mg per day. Children—Use and dose must be determined by your doctor. For Tourette's disorder: Children 6 to 18 years of age—At first, 2 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 20 mg per day. Children younger than 6 years of age—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include drowsiness, vomiting, aggression, confusion, tremors, fast or slow heart rate, seizure (convulsions), weak or shallow breathing, fainting, or coma.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Abilify MyCite dosage information

Side effects

The most common side effects associated with Arpicin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Increased numbers of cytoplasmic filaments adjacent to the plasma membranes at the invading pole of these cells were also observed. Further screening of suspected CF patients revealed a novel mutation that converted leucine at position 346 to proline (L346P) in two unrelated families. A study of the excretion of thymidine and beta-aminoisobutyric acid (BAIBA) in rats as a function of the administered dose of thymidine and DNA. Somatic cell hybrid DNA which contains chromosome 6 or chromosome 22 was restricted with either Notl or Mlul. The purification of activated Hageman factor (activated factor XII). those who spent more time outdoors because of occupational activities) need to be surveyed and protected against possible adverse health effects. Individual-level characteristics have failed to account for such gradients.

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This study was conducted to clarify the effects of patient health beliefs and satisfaction on compliance behavior. Processes that seem to facilitate identification include active encoding, active retrieval, and spontaneous use of verbal mediators. Oculogyric dystonic reaction to escitalopram with features of anaphylaxis including response to epinephrine. A questionnaire designed to assess depressive symptoms, the CES-D, was given to all patients consulting throughout the study period. The scientific community must weigh the risks and benefits of using biocides in clinical and community environments, to determine whether additional precautions are needed to guide biocide development and use.

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This article discusses the fundamentals of sexual functioning and describes the elements of a comprehensive, developmentally relevant sexual health assessment. Comparison to a sample of methadone maintenance clients from the same geographic area reveals that on average the community sample began heroin use later, attained a higher level of education, and were most likely to have had a significant cohabitation relationship. Targeting of endocytosis and secretion to the rhizoid cortex contributes to membrane asymmetry. 5) Animals in group II and III survived significantly longer than those in the other group. Exposure to fractionated UVA was followed by an increased rate of cell death compared to single dose exposure, when intervals between fractions where short (10-120 min).

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The study showed that subcultured dental pulp cells actively differentiate into odontoblast-like cells and induce calcification in an alginate scaffold. In this report, we show that GH and EPO induce the tyrosine phosphorylation of cellular proteins with molecular masses of 93 kDa and of 91 and 84 kDa, respectively, and that these proteins form DNA-binding complexes which recognize an enhancer that has features in common with several rapidly induced genes such as c-fos. The intraclass correlation coefficient (ICC) for inter-observer reliability of the sigma system was 0.89, with 73 of the 82 casts graded at the same level of photoageing by the two observers. Because expression of several mRNAs encoding ribosomal proteins was found strongly altered during colorectal carcinogenesis, sequence of these transcripts, not previously described in human, was completed and their expression analyzed. Patients reporting symptoms of bronchospasm were treated with prophylactic beta-agonist aerosol before subsequent AP treatment. Cavernous hemangioma, a rare vascular hamartoma, in the cavernous sinus is described in this report. Cathepsin H was purified by a single-step affinity chromatographic method from crude human kidney extract. In conclusion these three results taken together--the single-unit data, the Gerstein and Mandelbrot model, and the modeled collection of neurons--suggest that the analysis of the temporal dynamics of neural systems can be furthered by the application of nonlinear dynamical theory. Clinical significance of simultaneous investigation of blood escape curves of 198Au and of bengal red 131-I. When occupations were ranked according to PMRs from these diseases, striking differences were found.

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Although corticosteroids may produce depressive symptoms as a side effect, corticosteroid exposures are not associated with an elevated risk of clinically diagnosed depressive disorders in hospitalized patients. In each instance in which contrast-enhanced LN was identified with US, a corresponding SLN was detected by lymphoscintigraphy. At baseline, bronchoalveolar lavage fluid (BALF) ascorbic acid concentrations were lower in RAO-affected horses than healthy controls. Vaccines comprising combinations of diphtheria, tetanus and pertussis (DTP) components with Haemophilus influenzae b polysaccharide--protein conjugates (DTP-Hib) are now available. These data further extend observations that body weight is associated with both definite and bilateral knee OA in both sexes, and support a stronger contribution of mechanical as opposed to systemic factors to explain this association. NMR characterization of guanine DNA site alkylated by kapurimycin A3, an antitumour antibiotic from Streptomyces sp. Clinical treatment of neuropathic pain can be achieved with a number of different drugs, some of which interact with all members of the voltage-gated sodium channel (NaV1) family. The present result supported the notion that loss of the immunohistochemical reaction for CK-BB which has been observed by light microscopy after cerebral ischemia, was at least partly due to dispersion of this enzyme caused by disintegration of microtubules and extracellular leakage of this enzyme, although other processes, including degradation of CK-BB per se, were also possible. These data shed light on the HCV core residues involved in SPP cleavage and suggest that this cleavage is essential for HCV assembly. The superficial cells (SP cells) were desquamated after 12-O-tetradecanoylphorbol-13-acetate (TPA)-treatment, and the morphological changes of the regenerating epithelium were investigated by scanning and transmission electron microscopy.

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The relevance of such somatic hybrid material for the study of nucleocytoplasmic interrelationship is discussed, as well as the use of these fraction 1 protein isoelectric focusing patterns for the analysis of taxonomic relationships in Petunia. Nonmodifiable risk factors for surgical-site infection in spine trauma include age, medical comorbidities, and neurologic status. Oesophagostomum dentatum: population dynamics and synthesis of prostanoids by histotropic stages cultured in vitro. Even under reserpine, PGO waves occur with a definite rhythmic character having a basic rhythm of approximately 30-35 min, which is similar to the normal sleep EEG cycle in cats. Mifepristone appears to be a useful intervention for psychotic depression, leading to significant improvements even after a 1-week course of administration. It then pushes forward a bit, rotates ventrally during forebrain flexing, and gives rise to the chiasmatic ridge and anterior hypothalamus.

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The anatomical distribution of substance P-like immunoreactivity across the subnuclear divisions of the nucleus of the solitary tract has been examined in the human medulla oblongata. The high-dose feed groups showed more tendency to swim in the outer annulus or to swim very close to the walls of the tank (thigmotaxic behavior). Biodistribution studies were carried out in mice after intravenous administration of the labeled conjugate. Monoclonal antibodies for Streptomyces lividans and their use for immunomagnetic capture of spores from soil. Low doses of dapsone reduce toxic effects, but at the expense of some loss of efficacy. Hologram quantitative structure-activity relationship (HQSAR) studies were conducted on a series of potent FXR activators originated from natural product-like libraries. Irrespective of clamping level, the platelet count, clot retraction and prothrombin consumption do not undergo significant changes. Effect of isradipine on renal haemodynamics and systemic blood pressure changes induced by intravenous infusion of endothelin in healthy humans. The results show that while they were aware of lifts recommended by the RCN and by other researchers, they reported that they frequently used lifts not recommended by the above sources during their medical placement.

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Thirteen of the 28 patients treated for recurrence were alive and disease free at five years. The present study has shown a strong association of betel quid chewing (including tobacco as an ingredient) with the causation of OSMF. Fluconazole concentrations in saliva from AIDS patients with oropharyngeal candidosis refractory to treatment with fluconazole. Insulin-like growth factor binding protein 1 response to acute insulin induced hypoglycaemia in type 1 diabetes. Just such a case is described along with an appropriate recording technique. Cimetidine was replaced with mycostatin and after four weeks of treatment, the ulcers healed completely in four patients. A logical diagnostic approach to the patient should be based on clues obtained from careful history taking, physical examination, and review of routine laboratory cozaar 50 mg photo studies. Traumatic aneurysm of the superior mesenteric artery as the cause of massive upper gastrointestinal hemorrhage. In unactivated oocytes, no aster forms and the antigen remains unchanged. Continuous in vitro evolution of bacteriophage RNA polymerase promoters.

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Insight into the nature of these genetic factors is provided by evolutionary studies, notably the disposable soma theory, which suggests a central role of energy metabolism in determining life-span. This paper describes the roles and responsibilities of the associate director for medical tenormin medication education at the Primary Care Resource Center (PCRC), School of Medicine and Biomedical Sciences, State University of New York at Buffalo (UB). Magnetic resonance imaging: extensive malformation of cortical development in the left hemisphere. Limited acetylation of rACT with acetic anhydride led to loss of DNA binding and, conversely, DNA protected rACT from acetylation. This is because the maxillary bone is thin and more easily penetrated, and not because of a difference in biological behavior. Atrial natriuretic peptide and skeletal alpha-actin mRNAs were detected by in situ hybridization with specific sulfur-35 uridine triphosphate-labeled RNA probes in the serial sections.

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We have studied the adsorption of a number of organic molecules consisting of methyl, benzyl, and carboxylic groups on the rutile TiO2 (110) surface using both ab initio and atomistic simulation techniques. It can replace the traditional frozen section and be used as an alternate. Assay of lysergic acid diethylamide and its passage from blood into the perfused cerebral ventricles. In the former case, the auxin level is lower in veins than in the surrounding tissue, while in the latter, the auxin is present in greater abundance in veins. Does propofol or caffeic acid phenethyl ester prevent lung injury after hindlimb ischaemia-reperfusion in ventilated rats?. Confirmation of the safety of autologous blood donation by patients awaiting heart or lung transplantation. Synthesis and antipancreatitis activities of novel N-(2-sulfonylamino-5-trifluoromethyl-3-pyridyl)carboxamide derivatives as phospholipase A2 inhibitors.

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Epidemic of acute infectious lymphocytosis in school children in Strzelno. Since vernalization requirement and photoperiod sensitivity are ancestral traits in Triticeae species we suggest that wheat was initially a SD-LD plant and that strong selection pressures during domestication and breeding resulted in the modification of this tenormin dosage range dual regulation. SSSV appears unique to simple retroviruses by not harboring sequences in the Atlantic salmon genome. A simple method for direct quantitation of non-transferrin-bound iron (NTBI) in serum is introduced. Electrotonic transmission between two nerve cells in leech ganglion. Thus, the alpha-glucosidase inhibitor acarbose may have the potential to delay or possibly prevent the development of diabetic complications.

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On the contrary, PCL tear should never be isolated and always associated with peripheral ligament injuries. Pathogenetic implication of some laboratory parameters in the development of toxicohypoxic encephalopathy in acute poisoning by psychopharmacological agents. Twenty consecutive patients who underwent total hip or knee arthroplasty received a simple dressing--blue gauze and Tegaderm. A four-fold increase in transplant size, and greater cell and fiber densities were observed in NGF-treated compared with NGF-untreated transplants. The developmental and tissue-specific regulation of the hs response is discussed. These data suggest that plasma lipids are also related to CHD in the elderly and that, even if at present we are not able to consider them as predictors of longevity, some lipoprotein features may contribute to select subgroups of subjects in which other factors play a further role in life expectancy. In addition, eating habits formed during childhood have a potential lifelong effect on serum lipid levels, and thus, indirectly, on adult coronary heart disease risk. Chromosome typing in lymphangioleiomyomatosis of the lung with and without tuberous sclerosis. The ventral prefrontal cortex (PFC), the hippocampus, and the entorhinal cortex were selected.

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Odor discrimination and recognition memory as a function of familiarization. In waking, immobilized male newts, neurophysiological effects of AVT and CORT were studied in neurons in the rostral medulla due to the probable role of these neurons in the control of clasping. To explore potential effects of different genotypes on plasma lipid patterns, the lipoproteins of two families with hypobetalipoproteinemia were compared using zonal ultracentrifugation and chemical analyses. Systemic LPS injection was followed by a massive influx of macrophages into the retina. The anatomical connections between the midline cerebellum and the pontine parabrachial nucleus (PBN) were investigated in the rabbit using anterograde and retrograde axonal transport techniques.

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Long-term administration of misoprostol to cirrhotic rats restored to normal the responsiveness to NaNP, whereas long-term administration of aspirin to healthy rats resulted in a hyporesponsiveness of the gastric microcirculation to NaNP similar to that seen in cirrhotic rats. Finally, murine PKR activity and endogenous levels of eIF-2 alpha phosphorylation were reduced in the p58-expressing cell lines compared with neurontin 300 mg sirve para dormir control cells. Cryptococcus neoformans is a basidiomycetous human fungal pathogen that causes fatal disease in immunocompromised hosts. Drug treatment seems to be more cost effective than hyperthermia for BPH treatment. Since O6-MeGua is not excised from DNA by Mex- cells, it represents a novel type of processing of the methylated base that may be involved in its cytotoxicity. Since median eminence TRH-Gly levels were very low compared with other proTRH-derived peptides it is unlikely that alpha-amidation is a rate-limiting step in hypothalamic TRH synthesis. People aged 9 to 16 years were interviewed and also tested for filarial antigenaemia. Changes in insulin receptor tyrosine kinase activity associated with metformin treatment of type 2 diabetes. Long term treatment with nifedipine and nitrendipine, but not verapamil and diltiazem, may reduce plasma potassium levels in hypertensive patients. In the long term, an integrated, automated way to track individual patients across the continuum of care from the physician, to the hospital, and to home care is needed.

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