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We report on 19 patients with high stage seminoma who have been treated with platinum, vinblastine and bleomycin (14 patients) or platinum, vinblastine, bleomycin and doxorubicin hydrochloride (5 patients). Fetoscopic laser ablation is a safe and effective form of treatment in the management of severe twin-to-twin transfusion syndrome. A 3.6-mg depot of goserelin monthly subcutaneously or oral danazol 200 mg three times a day administered for 24 weeks. The transcription factor-like nuclear regulator (TFNR) contains a novel 55-amino-acid motif repeated nine times and maps closely to SMN1. Location of the sulfhydryl groups involved in disulfide interaction between the neighboring proteins L6 and L29 in mammalian ribosomes.
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Management of malignant ventricular arrhythmia--experience with lorcainide. However, the NT concentration in the MBH of TP-treated rats was almost twice the amount detected in oil-treated rats and with this peptide no significant changes were detected in the MPOA. The plant flavonoid pathway controls key reproductive and defense-related traits and responds to selection and environmental stressors, allowing for hypotheses about phenotypic divergence across environmental gradients. The effect on growth of the parasite, replication of DNA, mitochondrial membrane potential and level of reactive oxygen species after exposure to electric fields demonstrate that the parasite is biologically able to respond to stimuli from DC electric fields involving calcium signaling pathways. Generation of suppressor cells in the autologous mixed lymphocyte reaction. Serum beta 2--microglobulin and carcinoembryonic antigen in patients with gastric disorders. Stimulation by macrophages under activation by phagocytosis, lymphocyte factors, bacterial products or other inflammatory stimuli.
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TRH increases the pressor response to acetylcholine through an increment in muscarinic receptors. In the present study this has been achieved by experimentally reducing, through gestational treatment with methylazoxymethanol acetate (MAM), the population of cholinergic neurons of the medial habenula which projects to the interpeduncular nucleus. ORF65 protein was shown to be phosphorylated by casein kinase II. The quick-freezing and deep-etching method could be used to clarify the three-dimensional association between the cytoskeleton and membrane-bound organelles in hepatocytes. Treatment of the mild and moderate stages of the disease, although not yet proved to reduce mortality and morbidity, would appear to be justified since pressure control is readily achieved with the relatively non-toxic drugs currently available. The diagnosis of these lesions presents difficulties, the differential diagnosis including MS and its variants, neoplastic, infectious and vascular processes. Luminescent spectral study of the routes of terminal oxidation during changes in the functional activity of a single muscle cell. There was a significant difference (P less than 0.05) between 2 observers measuring the same records, but there was no significant difference between the two observers in the variance of the closing variability in the same subject, it may be necessary to perform several closing volume maneuvers in each subject to establish his or her range before changes in the closing volume can be interpreted. To this end, we tested the binding of appropriate monoclonal antibodies to a panel of cell lines and tumor sections.
We sought to evaluate the potential benefits of a computer-aided detection (CAD) system for detecting lung nodules in multidetector row CT (MDCT) scans. Future research would benefit particularly from studying the role of sports and physical activity mode as well as the psychological and social context in which it may produce beneficial psychosocial outcomes. Prostaglandin E2 is a potent endogenous molecule that binds to four different G-protein-coupled receptors: EP1-4. Preparation and some properties of maleimido acids and maleoyl derivatives of peptides. To investigate how prostatectomy for patients with benign prostate hyperplasia (BPH) affected the serum prostate-specific antigen (PSA) levels.
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The measurement of beclomethasone dipropionate entrapment in liposomes: a comparison of a microscope and an HPLC method. The levels of serum cobalamin, UTC I, UTC III, UBBC, alanine and aspartate aminotransferases, and bilirubin were raised in both hepatoma and viral hepatitis patients. A probe was synthesized by polymerase chain reaction with oligonucleotide primers based on the known amino acid sequences of two regions of the mature protein and first-strand cDNA as template. The most recent articles have suggested that open reduction through a posterior approach and internal fixation is the best way to treat this problem initially. Efficacy of single serum cortisol reading obtained between 9 AM and 10 AM as an index of adrenal function in children treated with glucocorticoids or synthetic adrenocorticotropic hormone. IgG subclasses with anti-NEP activity were determined by western blotting. The region 650 bp upstream of exon 1 was predicted to contain putative binding sites for SP1 and nuclear factor kappaB (NF-kappaB), but no sterol response elements (SREs) or retinoid X receptor (RXR) binding sites.
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Pathogenic bacteria must withstand diverse host environments during infection. An analysis and generalized experience of work done by the Soviet and foreign optical departments formed a background for working out a technology of assembling corrective spectacles and for drawing up a list of the equipment with due consideration for the output of the optical aids determined by the numerical strength of the population to be serviced. Perforation of a metastatic bronchogenic carcinoma to the jejunum. Detection of noncovalent complexes in the gas phase suggests that further use of conventional biochemical approaches to provide a qualitative, and in some cases even quantitative, characterization of equilibria of noncovalent complexes in solution is possible. Our results suggest that higher-connectance food webs tend to host fewer invaders and exert stronger biotic resistance compared to low-connectance webs. Electron density of mitochondria in sensory nerve endings have increased and its cristae have disappeared.
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Shifts in the hydrophobicity of the membrane DBH were also apparent. While IN-inoculated CsA-treated animals expressed higher virus infectivity titer in their lungs compared to oil-treated controls, this difference was not seen in the IP-inoculated groups. The array data suggested, and direct microscopic observation of cells expressing a derivative of green fluorescent protein with a peroxisomal matrix-targeting signal confirmed, that respiratory deficiency dramatically induces peroxisome biogenesis. However, these primary neurons can be rescued by transfection of a b-raf expression plasmid. Both Ucn 2 and Ucn 3 suppressed food intake in freely-fed rats, but not immediately after injection. The analysis for the most recent 9-year data (Lancet 361 (2003) 1686) employed conventional linear regression models. Mechanism of hypersensitivity to histamine of rats treated with Bordetella pertussis vaccine. In this paper we show the redesign of a therapeutically interesting trimeric all-beta-sheet protein, the cytokine TRAIL (tumor necrosis factor-related apoptosis-inducing ligand), yielding variants with improved thermal stability. S-layer-mediated association of Aeromonas salmonicida with murine macrophages.
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Their littermates without cleft lip rarely have a septal defect. We report the difference in activation volumes of wall-motion and nucleation processes in Co/Pd multilayers. Subjects are equipped with a finger-spanning device to continuously rate and log their perceived pain during fMRI data collection. The development of tolerance was determined to some extent by fixed-ratio size, a result similar to earlier findings with cocaine. Allergic inflammation as a hypothesis for the expulsion of worms from tissues. Using the heated thermocouple principle to monitor blood flow-rate in the choroid of the anesthetized cat and Rhesus monkey revealed that elevation of ocular pressure reduces blood flow-rate in the choroidal circulation. The inhibitory activity of 10 tryptic peptides of the coat protein of 2 strains of tobacco mosaic virus (TMV) was demonstrated by inhibition of ELISA and verified by inhibition of complement fixation tests. Detection of galactomannan antigenemia in patients receiving piperacillin-tazobactam and correlations between in vitro, in vivo, and clinical properties of the drug-antigen interaction.
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Intraliposomal ADP decreases and intraliposomal ATP increases the Km for cytochrome c when measured by the photometric assay under uncoupled conditions. Two lymphokines, lymphocyte-derived chemotactic factor (LDCF) and immune interferon, were assayed in supernatants of milk and blood lymphocyte cultures obtained from women 2 to 6 days postpartum. The maximum pressure is determined by the surface free energy of the liquid, the advancing contact angle of the liquid on the hydrophobic regions, and the channel depth. On the basis of these results along with our earlier observation regarding the action of hydroxyurea on thymidine kinase activity in 7-day-old cerebellum (1), we conclude that the inhibitory action of hydroxyurea on thymidine kinase activity is dependent on the proliferative stage of cells under study. Regarding hemodynamic, the role of increased venous pressure is more and more accepted as demonstrated by the increase in abdominal pressure.
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Antiallergic activity of a disaccharide isolated from Sanguisorba officinalis. The sexual maturation in the male house musk shrew, Suncus murinus, was investigated by weighing gonads, accessory sexual organs and various other organs, and measuring testosterone concentrations in the plasma from birth to 50 days of age. Connections of the small bipolar cells with the photoreceptors in the turtle. A reciprocal type of IFN produced in human PBML was absolutely dependent on the presence or absence of M phi. Initial results show that 3-D dynamic images can be obtained from these patients with minimal invasiveness and that these images may provide useful diagnostic information. Chromatin was in close association to the nuclear membrane and showed a punched-out appearance. Furthermore, the apparent persistence of the embryonic ganglioside GD3 in sg/sg mice results from an early-onset reactive gliosis, together with a partial retardation in granule cell maturation. Step 2 (early detection/case finding): pharmacists are often the first point of contact between the patient and the healthcare system and can therefore play an important role in the early identification of patients with COPD. The findings indicate that, in normal humans, an acute increase in irANF within or slightly above the physiological range, which modified natriuresis and diuresis, did not alter circulating plasma insulin.
Characterization of the endocannabinoid system in early human pregnancy. A comprehensive study of the postnatal changes in the concentration of the lipids of developing rat brain. However, the higher rate of TNFI discontinuation under the top-down approach requires further examination. Dual-specificity mitogen-activated protein kinase (MAPK) phosphatases (DUSPs or MKPs) are key regulators of pathway activity and may also localize ERK to distinct subcellular locations. It was difficult to control the heart rate with beta-blockers during AFL, which resulted in the deterioration of right-sided heart failure. Medium and high water content lenses produced good results without affecting the recipient cornea, whereas thick or low water content materials extruded or produced severe anterior segment inflammation. Localisation and characterisation of egg shell porphyrins in several avian species. New genes composed of the mouse metallothionein I promoter-regulator and the rat or human growth hormone structural gene have been introduced into mice. alpha-Fetoprotein and albumin were detected in one case, and alpha 1-antitrypsin and alpha-fetoprotein in the other. To determine whether genetic differences could contribute to the pharmacological sensitivity of lithium chloride (LiCl) to reverse amphetamine-associated changes in behavior C57BL/6nCrlBR and C3H/HenCrlBR male mice were tested for the ability of an acute dose of LiCl to reverse the locomotor enhancing effects of an acute dose of amphetamine.