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Aripat (Aripiprazole)
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Aripat

Aripat is an antipsychotic medicine used to treat schizophrenia, bipolar disorder, Tourette syndrome and irritability associated with autism. It may be used in combination with an antidepressant to treat depression.

Other names for this medication:
Apicord, Aridus, Arifril, Arilan, Arinex, Aripat, Aripicon, Aripiprazole, Aripra, Arpicin, Asprito, Biliff, Elrip, Pipra, Rizotal, Schizopra

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Also known as: Aripiprazole

Description

The Abilify Maintena brand of aripiprazole is used to treat schizophrenia and bipolar I disorder (manic depression) in adults. The Aristada brand of Abilify Maintena is for use only in treating schizophrenia in adults.

Dosage

This section provides information on the proper use of a number of products that contain aripiprazole. It may not be specific to Abilify Mycite. Please read with care.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not open the blister pack that contains the tablet until you are ready to take it. Remove the tablet from the blister pack by peeling back the foil, then taking the tablet out. Do not push the tablet through the foil. Do not break or split the tablet. Place the tablet in your mouth. It should melt quickly. After the tablet has melted, you may swallow or take a sip of water.

Swallow the tablets whole. Do not break, crush, or chew them.

Abilify Mycite® has a sensor in the tablet, which helps track it inside the stomach or bowels. The Abilify Mycite® System comes with a patch (wearable sensor), a smartphone application (app), and a web-based portal. Follow your doctor's instructions on how to use the medicine.

The Abilify Mycite® tablet is usually detected within 30 minutes after you take it, but there may be a delay of more than 2 hours for the smartphone app and web portal to detect that you have taken the medicine, and sometimes it might not be detected at all.

To apply the Abilify Mycite® patch:

The app will tell you when to apply or remove the patch. It should be changed weekly or sooner as needed. Place the patch to the left side of your body just above the lower edge of your rib cage. Do not put the patch in areas where the skin is scraped, cracked, inflamed, or irritated, or near the area where you had removed the previous patch. The app will help you place the patch in the correct location. You may keep the patch on when showering, swimming, or exercising.

Aripiprazole may be taken with or without food. If your doctor tells you to take it a certain way, follow your doctor's instructions.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (tablets and orally disintegrating tablets): For bipolar mania: Abilify® and Abilify Discmelt®: Adults—At first, 15 milligrams (mg) once a day. When it is given with lithium or valproate, the starting dose is 10 to 15 mg once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 30 mg per day. Children 10 years of age and older—At first, 2 mg once a day. The dose will be gradually increased to 10 mg once a day. Your doctor may adjust your dose again as needed. However, the dose is usually not more than 30 mg per day. Children younger than 10 years of age—Use and dose must be determined by your doctor. Abilify Mycite®: Adults—At first, 15 milligrams (mg) once a day. When it is given with lithium or valproate, the starting dose is 10 to 15 mg once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 30 mg per day. Children—Use and dose must be determined by your doctor. For depression: Adults—At first, 2 to 5 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 15 mg per day. Children—Use and dose must be determined by your doctor. For irritability in children with autistic disorder: Children 6 to 17 years of age—At first, 2 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 15 mg per day. Children younger than 6 years of age—Use and dose must be determined by your doctor. For schizophrenia: Abilify® and Abilify Discmelt®: Adults—At first, 10 to 15 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 30 mg per day. Children 13 to 17 years of age—At first, 2 mg once a day. The dose will be gradually increased to 10 mg once a day. Your doctor may adjust your dose again as needed. However, the dose is usually not more than 30 mg per day. Children younger than 13 years of age—Use and dose must be determined by your doctor. Abilify Mycite®: Adults—At first, 10 to 15 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 30 mg per day. Children—Use and dose must be determined by your doctor. For Tourette's disorder: Children 6 to 18 years of age—At first, 2 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 20 mg per day. Children younger than 6 years of age—Use and dose must be determined by your doctor.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include drowsiness, vomiting, aggression, confusion, tremors, fast or slow heart rate, seizure (convulsions), weak or shallow breathing, fainting, or coma.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Abilify Discmelt dosage information

Side effects

The most common side effects associated with Aripat are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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Mutations in StAR are now shown to cause Congenital Lipoid Adrenal Hyperplasia, the last unsolved form of CAH. The data of 476 patients with a carcinoma in the lower third of the rectum who underwent primary treatment for stage I-III disease by low anterior resection, abdomino-peranal (intersphincteric) resection or abdominoperineal excision between 1985 and 2001 were analysed. Eccrine syringofibroadenoma of clear cell variant: an immunohistochemical study. Evidence of acute infection is unusual even with widespread disease. parvum in the host is the intestinal epithelial cell, resulting in diarrhea, sometimes profuse and persistent, although it may also infect other organs such as the gall bladder and lungs.

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AIDS and families: cultural, psychosocial, biaxin ear infection and functional impacts. CFTR and calcium-activated chloride currents in pancreatic duct cells of a transgenic CF mouse. Multiple regression was used to determine significant variables in predicting fire injuries in a given census tract over a nine-year period and interaction effects between two of these variables-age of housing and income. Identification of novel mutations of the human N-acetylglutamate synthase gene and their functional investigation by expression studies. Sphingosine 1-phosphate (SPP) actually induced expression of these oncogenes and activated AP-1. The mucopolysaccharidoses, first described at the beginning of this century, are still subject of research. The deficit in SCID mice is in a factor that is required for both of these pathways.

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ERPs were measured time-locked to cue onset, and time-locked to probe stimulus onset. Vascular endothelial growth factor (VEGF) is a heparin-binding, endothelial cell-specific mitogen. Advantages of the stress imaging modalities in comparison with standard exercise electrocardiography include greater accuracy when the resting electrocardiogram shows abnormal findings, higher sensitivity, ability to localize and characterize the extent of myocardial ischemia, and direct measurement of other variables such as left ventricular function. Mean amplitude of the waves (10 to 50 muV) noroxin generic showed an inverse exponential relationship with frequency. The article analyzes these as the ideological equivalents of immunosuppressant drugs, designed to inhibit cultural rejection of transplantation and its view of the body. These relaxation responses were inhibited by NG-nitro-L-arginine, hemoglobin, and methylene blue and were considered to be associated with the production and/or release of endothelium-derived relaxing factor-nitric oxide (EDRF-NO). A simple and comfortable technique for replacing ureteric stents in patients with strictured uretero-intestinal anastomosis or strictures at the vesico-ureteric junction. Patients were randomly assigned to one of two groups, to receive GM at a dose of 600 mg/24 hr (treated group: 8 patients) or a physiological solution (control group: 8 patients) by continuous intravenous infusion.

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Messenger RNA levels of genes involved in dysregulation of postprandial lipoproteins in type 2 diabetes: the role of Niemann-Pick C1-like 1, ATP-binding cassette, transporters G5 and G8, and of microsomal triglyceride transfer protein. Further studies in solid phase synthesis of oligodeoxyribonucleotides through phosphotriester intermediates. Therefore, in the San Antonio Heart Study, a population-based study with worsening obesity, we examined the metabolic syndrome and its effect on incident cardiovascular disease (CVD). This chapter presents experimental methods to measure in vivo uteroplacental nutrient substrate uptake, transfer to the fetus, and metabolism by the uteroplacental unit. Prevention and managed care: opportunities for managed care organizations, purchasers of health care, and public health agencies. The steroid effect on critically ill patients remains controversial. Some effective conventional psoriasis treatments alter IL-12 levels. In spite of the apparent lack of viral receptor CD21, these benicar reviews comments nonlymphoid cells appeared susceptible to EBV penetration and infection through fusion with the plasma membrane at the surface of the cells. Comparative and functional genomic analyses of the pathogenicity of phytopathogen Xanthomonas campestris pv.

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Mycobacterium avium complex pulmonary disease (MAC-PD) is associated with substantial morbidity, and standard daily multidrug therapy is difficult to tolerate. On the influence of X-ray irradiation and photochemotherapy with 8-methoxypsoralen on the sebaceous gland of the Syrian hamster ear. Schizophrenia might appear to be an obstacle to the initiation of and especially compliance with antiretroviral therapy for HIV-infected patients. This seems to be an argument for the effectiveness of higher dosed aprotinin application in preventing scu-PA activation. As an in vivo model of encephalitis, wild-type or TLR3(-/-) mice were injected intracerebroventricularly with poly(I:C) or LPS, and microglial activation was assessed by cell surface marker or phospho-MAPK immunofluorescence. Conjunctival impression cytology as an indicator of vitamin A status in lactating Indonesian women. Further investigations should provide a simple and optimal indicator of abdominal obesity which should correlate with the amount of viscelar fat and the risk. The rural/urban variation in causation of death is discussed and the study results compared with other community based studies internationally. 16 male hypertensive patients who could be compared according to the behaviour of blood pressure and the heart frequency in the psychophysiological experiment, according to age the characteristic signs of the profession underwent a long-term therapy with propranolol. NAAs have generally low toxicity in laboratory animals (e.g., the LD50 of NBBA was more than 3,000 mg/kg, i.v.

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Activation of the hedgehog pathway in human hepatocellular carcinomas. At 11 years, she could walk with support, but could not stand up without assistance. Phase II trial of mitomycin-C in squamous cell carcinoma of the uterine cervix: a Gynecologic Oncology Group study. Succinic acid, 5-azacytidine, daunomycin, and hemin showed a positive effect. Six patients remained totally dependent while two became independent in daily activities. This finding was in agreement with the recently proposed role of GSH as a mechanism for quenching reactive aldehydes generated during the catabolism of these compounds (M. FOG-1 expression was higher in the beta-chain-negative hematopoietic progenitor cell line Ba/F3 than in the beta-chain-positive mast cell line PT18. While social stimuli automatically elicit responses via bottom-up processes, responses to the same stimuli can be modulated by explicit instructions via top-down processes. Quantitative analysis of metamorphosis induced by L-glutamine in embryos of the sea urchin, Hemicentrotus pulcherrimus.

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It is closely related to Arabidopsis thaliana, but shows considerably higher salt tolerance. Acquisition of meiotic competence by denuded mouse oocytes: participation of somatic-cell product(s) and cAMP. Sample plasma was deproteinized with a fourfold volume of methanol. Here, we review the role of animal lectins in the migrating phenotype of neoplastic cells and normal cells such as T-lymphocytes. mpk1Delta MAPK mutant strains exhibited fludioxonil hypersensitivity, indicating that this pathway also contributes to drug resistance. In its C-terminal half, PilA has extensive homology with the 54 kDa protein of the eukaryotic signal-recognition particle which is involved in protein secretion. Coronary blood flow (CBF) and blood pressure (BP) did not change significantly in any treatment group.

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The most commonly recognized bands in both groups were 18 and 98 kDa antigens for IgG1 and 18, 45, 66, 98, 130 and 180 kDa for IgG4. The cleft children had the lip, soft palate, and posterior part of the hard palate repaired at 4 months of age. Function of the quadriceps femoris muscle under the full range of forces and differing contraction velocities of concentric work. To compare selected characteristics (age, sex, age of onset for depression, impairment, severity of depression, somatic comorbidity, and treatment status) of adolescents with currently comorbid and singulair 5 mg coupon non-comorbid depression. Preparatory training of primary health care nurses for handling health education regarding prophylaxis of circulatory disorders. Characterization of Cryptocaryon irritans isolates from marine fishes in Mainland China by ITS ribosomal DNA sequences. The rfb locus from Pseudomonas aeruginosa strain PA103 promotes the expression of O antigen by both LPS-rough and LPS-smooth isolates from cystic fibrosis patients. Sleep pattern was significantly associated with migraine and tension-type headache in both univariate and multivariate analyses. Detection of schistosome ova by dark field fluorescence microscopy. Treatment of the neurogranin peptide with protein kinase C eliminated its inhibition on nitric oxide synthase activation.

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Radiofrequency energy was effectively delivered for 30 seconds with a stable ablation catheter position, and termination of rapid pacing resulted in sinus rhythm. Experiences with choriogonin therapy of female sterility associated with the absence of ovulation or insufficiency of the corpus luteum. Growing bacteria are sensitive to various beta-lactam derivatives due to their interference with peptidoglycan biosynthesis. We present an alternative method of administering these agents to provide pain relief in the orthopedic patient. Antigenic variation of pilin regulates adhesion of Neisseria meningitidis to human epithelial cells. Some aspects of the blood in infantile diabetes (proteins, glycoproteins, lipoproteins, cholesterol).

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This paper is based on experiences in developing a dental program for homeless persons in Boston. Three years later, progression of the disease has ceased, and the involved bone is slowly remineralizing. Dephosphorylation of the small heat shock protein Hsp27 in vivo by protein phosphatase 2A. In clinically achievable concentrations, the combination of estramustine and colchicine was cytotoxic to both the Dunning rat prostate adenocarcinoma cell line MAT-LyLu (MLL) and human prostate cancer cells (PC-3). For non-responders of the drug, the synergism seems to be stronger, showing no deaggregatory pattern. Cerebral angiography is the main diagnostic procedure which confirms the diagnosis of moyamoya disease. Alternatively, the assay may be used to study the effect of recombinant gene expression on parasite invasion and development. To review the overall performance of a neonatal screening program for cystic fibrosis (CF) from 1981 to 1994, and to compare two strategies of case detection. Isodose curves for certain radium applicators used in the treatment of uterine cervical cancer. Our studies support that trophoblastic fusion in placental morphogenesis depends on the regulation of GCMa activity by HAT and HDAC.

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Accordingly, we diagnosed this patient with AFP- and DCP-producing adenocarcinoma of the stomach together with liver metastasis. Antigen presentation by a mouse duodenal epithelial cell line (MODE-K). The secretion of somatostatin-14 was suppressed by insulin in the presence of 5 and 10 mM glucose and was stimulated by glucagon in the presence of high (10 mM) glucose. No significant differences in the time-course of clinical observations or plasma concentrations of the biomarkers of infection were observed between the two treatments. Immunoreactive gold particles of hCG are preferentially localized in the distal portion of the Golgi complexes, Golgi-derived secretory granules 200-300 nm in diameter, and large electron dense bodies 500-1,000 nm in diameter. Homeopathy might require both local and non-local mechanisms to describe fully its mode of action. In addition, the matrix proteins of all field strains isolated after 1977 showed slower electrophoretic mobility of 42 K than 39 K of the Edmonston and Toyoshima strains.

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