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Aricep (Donepezil)

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Aricep is indicated for the treatment of dementia of the Alzheimer's type. Efficacy has been demonstrated in patients with mild, moderate, and severe Alzheimer's disease. Alzheimer's disease is a form of dementia. It is a progressive, neurodegenerative disease characterized by loss of cognitive function such as memory and language.

Other names for this medication:
Alzil, Aricep, Demenza, Depzil, Donasure, Donaz, Donecept, Donep, Donepezil, Dopezil, Dorent, Nepzil, Nozil, Pezil

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Also known as: Donepezil


Aricept ODT is used to help improve mental function in people with Alzheimer's disease.

Aricept ODT does not work the same in all people. Some people taking Aricept ODT have improved mental function, while others may have unchanged or even worsening mental function.

Aricept ODT is not a cure for Alzheimer's disease. This condition will progress over time, even in people who take this medicine.

Aricept ODT may also be used for other purposes not listed in this medication guide.


Usual Adult Dose for Alzheimer's Disease:

Initial dose: 5 mg orally once a day, in the evening prior to retiring Mild to moderate Alzheimer's disease: -Maintenance dose: 10 mg orally once a day, after the patient has been on an initial dose of 5 mg once a day for 4 to 6 weeks Moderate to severe Alzheimer's disease: -Maintenance dose: 23 mg orally once a day, after the patient has been on a dose of 10 mg once a day for at least 3 months Comments: A higher dose of 10 mg may or may not provide a statistically significantly greater clinical benefit than a 5 mg dose. Prescriber and patient's preference should be considered. Uses: For mild, moderate, and severe Alzheimer's type dementia

Detailed Aricept dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include severe nausea, vomiting, drooling, sweating, blurred vision, feeling light-headed, slow heartbeat, shallow breathing, muscle weakness, fainting, or seizure (convulsions).


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of reach of children.

Side effects

The most common side effects associated with Aricep are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Aricept if you are allergic to donepezil or certain other drugs. Tell your doctor if you are allergic to any medicines.

To make sure Aricept is safe for you, tell your doctor if you have:

a heart rhythm disorder; a history of stomach ulcers; an enlarged prostate or urination problems; liver or kidney disease; epilepsy or other seizure disorder; trouble swallowing; or asthma, chronic obstructive pulmonary disease (COPD), or other breathing disorder.

It is not known whether Aricept will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.

It is not known whether donepezil passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

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Nostril capsaicin application as a model of trigeminal primary sensory neuronal activation. Molecular cloning, nucleotide sequence, and expression of the gene encoding a trypsin-like protease from Streptomyces erythraeus. Young subjects spent more time in contact with their mothers but showed no changes in social grooming. These coagulation changes range from minor, single parameter abnormalities to multicomponent, critical value derangements. According our results the low-risk patients of early stage endometrial adenocarcinoma had excellent survival with minimal intervention. The Siemens disk picture storer, a new magnetic single picture storer and its importance in the field of roentgenographic and fluoroscopic technic. Key research findings relative to the question of whether maternal use of folic acid before and during pregnancy reduces the chance that offspring will be born with a congenital heart defect or an orofacial cleft are reviewed in this paper. Lower doses of these agents are now being investigated, but the weight of evidence is against agents that operate primarily through phosphodiesterase inhibition. We produced a panel of monoclonal antibodies (mAbs) directed against the extracellular domain of the human receptor.

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This indicates that water in Neubecks Ck is toxic to biota, but that sediment is able to support aquatic biota in clean water. It also addresses how rethinking clinical documentation and IT together may improve the entire healthcare process by promoting a more integrated and patient-centered healthcare information paradigm. Here the most common types of infections, or infecting organisms, are described together with reported successful therapies. Ethnic differences in blood pressure control among men at Veterans Affairs clinics and other health care sites. Event-related brain potentials elicited by semantic and syntactic anomalies during auditory sentence processing.

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Complexes of tissue kallikrein with protein C inhibitor in human semen and urine. Recent cloning of an inducible human NO synthase reveals new perspectives. Recent legislation coming into force on 1 January 1995 has established the European Medicines Evaluation Agency and introduced revised systems for approving pharmaceutical products, including blood products. Thapsigargin and di-tert-butylhydroquinone induce synergistic stimulation of DNA synthesis with phorbol ester and bombesin in Swiss 3T3 cells. In vitro binding analyses using glutathione-S-transferase fusion proteins of various deletion mutants of domain E narrowed down the sequence necessary for the ZO-1/ZO-2 association into the domain E358/504. HLA DNA preorgan retrieval donor typing in renal transplantation. The authors suggest that such computer models can be useful tools for systematic analysis of potential impacts in land use planning. The mitochondrial membrane potential was altered and cytochrome c and Smac were released from mitochondria to the cytoplasm upon justicidin A treatment.

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Radical lymphadenectomy in the primary carcinoma of the fallopian tube. Nucleotide sequence analysis of region B revealed two open reading frames, which encode proteins with molecular masses of 45.1 and 48.7 kDa. biflexa serovar patoc strain Patoc I, extracted by the method of SiO2-high concentration salt solution (8 mol/L GuHCl) absorption, with the 16S rRNA gene primers of Leptospira interrogans by reverse transcription-polymerase chain reaction (RT-PCR). Because of the high risk, thoracic aortic surgery was not performed. Effects of exogenous adenosine on myocardial recovery after acute hemorrhage. Human replication protein A can suppress the intrinsic in vitro mutator phenotype of human DNA polymerase lambda.

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Clinical and experimental observations of buzhong yiqi decoction in the treatment of chronic hepatitis B. Ultrasound biomicroscopy findings of 25 G Transconjuctival Sutureless (TSV) and conventional (20G) pars plana sclerotomy in the same patient. An improved method for the quantitative biological determination of the calcinosis factor. Cerebral hypoperfusion on single photon emission computed tomography is the main criterion for selection of patients for cerebral revascularization. Adrenocortical carcinoma in children: clinical aspects and prognosis. To investigate the possible involvement of E2F in hematopoietic malignancies, we isolated genomic clones encompassing the human E2F1 gene. Radiation therapy of primary malignant tumors of the nasal fossa. The presence of the Ro protein was detected with a molecular weight of 60 kD during all phases of the cell cycle, except at the M phase, where it was increased to 65 kD. (Apropos of 25 cases observed at the Sanatorium des Neiges at Briancon).

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Integrating sexual and reproductive rights into the medical curriculum. Studies on the therapeutic effect of monomycin on white mice infected with Mycobacterium leprae murium. These results indicate that FR234938 has potential anti-inflammatory activity. Improvement in integrative processes is the basis for raising the quality of radiodiagnosis in a general hospital. Quality improvement implementation, in turn, was positively associated with greater perceived patient outcomes and human resource development. The use of upper gastrointestinal (GI) fiberoptic endoscopy has spread at different times and rates in Japan than in the United States.

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An understanding of these cytokine networks may suggest novel treatment strategies for HIV-seropositive persons. To test the hypothesis that local proliferation contributes significantly to the hyperplasia of rheumatoid synovium. Non-H-2-linked genetic control of resistance to BALB/c fibrosarcoma Meth-A. Mitochondrial network complexity and pathological decrease in complex I activity are tightly correlated in isolated human complex I deficiency. Favorable development of ability to function in patients during admission in a geriatric unit of a psychiatric hospital. The similarity between the two alternatives was varied systematically in order to achieve a parametric variation of decisional effort. Autoantibodies to nuclear lamins and to intermediate filament proteins. Here we present in vitro studies of yeast homolog Hst2 that shed light on the mechanism of Sir2 proteins. Release from Entex PSE was more consistent and more gradual than that from some of the comparison products. The effect of graded ascorbic acid intake on the activity of GSH-Px in the liver of female guinea pigs.

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Herpes zoster and quality of life: a self-limited disease with severe impact. Of all methods evaluated to date the judicious combination of surgery and radiation seems to hold the most promise for producing permanent local control of a significant percentage of canine and feline sarcomas. The Rex proteins of the delta-retroviruses act to facilitate the export of intron-containing viral RNAs. The coronary angiography strategy also led to lower mortality when vascular surgery was particularly risky. Southern blots of NotI-, NaeI-, KspI- and BamHI-digested DNA from early-feathering (EF) and LF White Leghorns, that had been hybridized with a probe that flanks ev21, indicated a 180 kb duplication of an unoccupied repeat in the LF genotype of White Leghorns. However, no significant alterations in gene expressions were detected after cyclic stretching of ligament cells derived from non-OPLL patients. With simulations we show that an artifact can be reproduced by applying filtered backprojection (without corrections for attenuation) of attenuated and blurred projections. Pushing in the expulsive phase of labour can be forced or follow the spontaneous urge to bear down. In short term sedation, propofol, despite its generally higher acquisition costs, has the potential to reduce overall medical costs if patients are able to be extubated and discharged from the ICU sooner.

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Standard nourished patients (7/14) received a 30 Kcal/kg/day support, the undernourished ones (6 low, 1 moderate malnutrition) received a 35-40 Kcal/kg/day support. Modified low-potassium dextran solution in heart-lung transplantation. The individual ceases to interact with the world because the lack of executive control makes such interaction difficult. GMBF increased significantly more with amoxil infant dose dopexamine-norepinephrine than with epinephrine between T1 and T3 (median values 106, 137, 133, and 165 versus 76, 91, 90, and 125 units of relative flux at T0, T1, T2 and T3, respectively). Estrogen and progesterone receptor analysis in pregnancy-associated melanoma: absence of immunohistochemically detectable hormone receptors.

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Although three factors affected sleep independently, ADL has an interactive effect on sleep with dementia and with PVL. Since there is minimal redistribution of sestamibi over time, it may overestimate nonviable myocardium in patients with left ventricular dysfunction, in whom blood flow may be reduced at rest. To explain the action of glycerol in reducing the thermal stress and preventing the ice fracture, a further study on ice crystal formation and growth of ice in these solutions was undertaken using cryomicroscopy. Synthesis and cytogenetic studies of structure--biological activity relationship of esters of Hecogenin and aza-homo-Hecogenin with N,N-bis(2-chloroethyl)aminocinnamic acid isomers. It is also shown that the kinetics of apoptotic cell death induced by gamma-irradiation correlated with the rapidity of exit from gamma-ray-induced G2 arrest for all the different hematopoietic cell types indicated above. Increasing walking for exercise, without making other changes, can improve body mass index, anthropometric measures, and attitudes, which are associated with improved quality of life and reduced risk of cancer recurrence. Evaluation of the programmes demonstrates the value of emphasizing the immediate effects of smoking, and the need to give children the ability to cope with social pressures before they reach secondary schools.

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Data were collected prospectively over 18 months on psychiatric symptoms and service use. This study compares the sensitivity and specificity of CAP with that of modified RAST in the detection of specific immunoglobulin E, and it assesses the correlation of the individual class scores of CAP and modified RAST with end points obtained from skin-dilutional end-point titration. Contextual effects in judgment as a function of restrictions in response-language. The cytoplasmic receptor sequences required for the transcriptional control via the IL-6 response element (IL-6RE) and motrin dosing peds the hematopoietin receptor response element (HRRE) in hepatoma cells were defined by transient expression of wild-type and mutant granulocyte-colony stimulating factor receptor-gp130 chimeric receptors. Two new alleles (A and E) of the bovine MUC locus which encodes PAS-1 protein, a glycoprotein of the milk fat globule membrane, are reported. Core curriculum for training in behavioral neurology and neuropsychiatry. This finding did not, however, explain the concentration of T-cell recognition on this part of the molecule.

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Coffee phagia and iron-deficiency anaemia: a possible association with Helicobacter pylori. Research on spontaneous and experimental masculinization of the submaxillary glands in the female mouse. Involvement of protein kinase C in proliferative response of osteoblastic cell lines stimulated with prostaglandin E2. The paper describes a case of prenatally diagnosed congenital brain tumor of an extremely rare histological type--oligodendrocytoma. Event-driven time-optimal control for a class of discontinuous bioreactors. It remains to be elucidated how these changes in the hatchling might be linked to the observed long-term consequences during posthatch life of the chicken. The value of routine serologic tests for syphilis on hospital admission. The behavior of these epithelioid sarcomas in children is similar to that seen in adults, the prognosis being dependent on radical tumor surgery preventing recurrent disease. In four patients, the MCS devices were implanted in the interhemispheric fissure to reduce lower-extremity pain. Analysis of peripheral blood actos generic form lymphocytes from specific pathogen free cats suggested that failure to react with the vpg39 antibody was an inherited trait.

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Principles of the construction of the therapeutic diagram in syphilis therapy (prepared plan of revised instructions for treatment of patients with syphilis). Should ACE inhibitors be administered to all patients with acute myocardial infarction?. However, the CNTF receptor complex also includes a CNTF-specific component known as CNTF receptor alpha (CNTFR alpha). To determine the effect of aging on functionality, doenjang fermented for 3, 6, and 24 mo were evaluated. Another conspicuous angiographic finding was a berry aneurysm associated with a daughter aneurysm at th basilar top. In shunt nephritis, circulating immune complexes are formed which contain antigen from bacteria of low virulence. Constitutive repression and nuclear factor I-dependent hormone activation of the mouse mammary tumor virus promoter in Saccharomyces cerevisiae. Androgens were not confirmed to participate in these changes in bone metabolism, but the reduction in serum levels of estradiol, as a major factor, and the reduction in serum levels of estrone, as a participating factor, were assumed to result in an increase in bone resorption in excess of bone formation.

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Pneumatosis cystoides intestinalis associated with Steinert disease. Virilizing adrenal carcinoma in a woman of reproductive age: a case presentation and literature review. fMRI studies of sensitivity and habituation effects within the auditory cortex at 1.5 T and 3 T. A total of 62 patients: 47 with primary kidney disease and 15 with diabetic nephropathy. Rehabilitation of schizophrenic patients through community mental health activities. In contrast to hBD2, hBD3 expression was NOD1-independent but EGFR and ERK pathway-dependent. There is a growing body of low-resolution structural data that can be utilized to devise structural models for large RNAs and ribonucleoproteins. This technique is a practical option in salvage operations for failed ACF.

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