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Aplenzin (Bupropion)

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Aplenzin is an antidepressant medication used to treat major depressive disorder and seasonal affective disorder. The Zyban brand of Aplenzin is used to help people stop smoking by reducing cravings and other withdrawal effects.

Other names for this medication:
Aplenzin, Budeprion, Bupdep, Bupraset, Bupron, Bupropion, Ession, Nicotex, Smoquit, Unidep, Zyban

Similar Products:
Sildigra, Chloromycetin, Dostinex, Elocon, Atarax, Singulair, Thorazine, Coreg, Differin

Also known as: Bupropion


Wellbutrin SR is an antidepressant used to treat major depressive disorder and seasonal affective disorder. The Zyban brand of bupropion is used to help people stop smoking by reducing cravings and other withdrawal effects.


Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Too much of this medicine can increase your risk of a seizure.

You may take Wellbutrin SR with or without food.

Swallow the extended-release tablet whole and do not crush, chew, or break it.

You should not change your dose or stop using Wellbutrin SR suddenly, unless you have a seizure while taking this medicine. Stopping suddenly can cause unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.

If you take Zyban to help you stop smoking, you may continue to smoke for about 1 week after you start the medicine. Set a date to quit smoking during the first 2 weeks of treatment. Talk to your doctor if you have trouble quitting after taking Zyban for 7 to 12 weeks.

Your doctor may prescribe a nicotine replacement product (such as patches or gum) to help you stop smoking. Start using the nicotine replacement product on the same day you stop (quit) smoking or using tobacco products.

Some people taking Wellbutrin SR (Wellbutrin or Zyban) have had high blood pressure that is severe, especially when also using a nicotine replacement product (patch or gum). Your blood pressure may need to be checked before and during treatment with this medicine.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

You may have nicotine withdrawal symptoms when you stop smoking, including: increased appetite, weight gain, trouble sleeping, trouble concentrating, slower heart rate, having the urge to smoke, and feeling anxious, restless, depressed, angry, frustrated, or irritated. These symptoms may occur with or without using medication such as Zyban.

Smoking cessation may also cause new or worsening mental health problems, such as depression.

This medicine may affect a drug-screening urine test and you may have false results. Tell the laboratory staff that you use Wellbutrin SR.

Store at room temperature away from moisture, heat, and light.

Detailed Wellbutrin SR dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of bupropion can be fatal. Overdose symptoms may include muscle stiffness, hallucinations, fast or uneven heartbeat, shallow breathing, or fainting.


Store at room temperature between 15 and 30 degrees C (59 to 86 degrees F) away from moisture and heat. Protect from light. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Aplenzin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Wellbutrin XL if you are allergic to it, or if you have:

a seizure disorder; an eating disorder such as anorexia or bulimia; or if you have suddenly stopped using alcohol, seizure medication, or a sedative (such as Xanax, Valium, Fiorinal, Klonopin, and others).

Do not use an MAO inhibitor within 14 days before or 14 days after you take Wellbutrin XL. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Do not take Wellbutrin XL to treat more than one condition at a time. If you take this medicine for depression, do not also take Wellbutrin XL to quit smoking.

Wellbutrin XL may cause seizures, especially if you have certain medical conditions or use certain drugs. Tell your doctor about all of your medical conditions and the drugs you use.

Tell your doctor if you have ever had:

a head injury, seizures, or brain or spinal cord tumor; narrow-angle glaucoma; heart disease, high blood pressure, or a heart attack; diabetes; kidney or liver disease (especially cirrhosis); depression, bipolar disorder, or other mental illness; or if you drink alcohol.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor will need to check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Ask your doctor about taking this medicine if you are pregnant. It is not known whether Wellbutrin XL will harm an unborn baby. However, you may have a relapse of depression if you stop taking your antidepressant. Tell your doctor right away if you become pregnant. Do not start or stop taking this medicine without your doctor's advice.

If you are pregnant, your name may be listed on a pregnancy registry to track the effects of bupropion on the baby.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

Wellbutrin XL is not approved for use by anyone younger than 18 years old.

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Ethical, legal, and social implications of incorporating genomic information into electronic health records. CRISPR-Cas gene-editing reveals RsmA and RsmC act through FlhDC to repress the SdhE flavinylation factor and control motility and prodigiosin production in Serratia. AUTONOMIC CHANGES PRODUCED BY NOXIOUS AND INNOCUOUS STIMULATION. Comparative influence of D-tubocuranine on the neuroadrenal junction and on the ganglionic synapses. Responsible conduct of research (RCR) education is now common throughout the United States, primarily in response to federal requirements beginning with the National Institutes of Health in 1989. Quiz page November 2013: an unusual cause of nephrotic syndrome: minimal change disease (MCD).

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Genes involved in innate immunity associated with asbestos-related fibrotic changes. This is the first study to compare the outcomes of retrorectus self-adhering mesh and transfascially sutured mesh in abdominal wall reconstruction. Comparison of Nelson-Mayer test with classical serologic methods. We sought to imitate angiographic cerebral circulation time (CCT) and create a similar index from baseline CT perfusion (CTP) to better predict vasospasm in patients with subarachnoid hemorrhage (SAH). The phenomenon gets it name because only transcriptionally active rRNA genes give rise to a nucleolus, the site of ribosome assembly. Describe the seizure-related manifestations of guanidinoacetate methyltransferase (GAMT) deficiency in two new cases and compare these to the related literature. The purpose of this study was to clarify how illness impacts the normative development of adolescent survivors of brain tumors by comparing them to healthy adolescents in terms of resilience and how it is affected by various health problems. Mepyramine pretreatment abolished both immediate headache and delayed migraine attacks. Underlay or retrorectus mesh placement is associated with lower recurrence rates.

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